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Predisposing Pathophysiology of Angina Pectoris Precipitating factor:

Factor:
Blockage of coronary
Age artery
Gender Coronary artery
spasm
Heredity
Obesity
Race
Hypertension
Coronary vessels are not efficient Sedentary lifestyle
Increase serum
cholesterol level
Vessels become lined and eventually
occluded with atherosclerotic plaque Cigarette smoking
and thrombi

Vessels can no longer dilate properly

Collateral vessels develop to provide


myocardium with needed arterial
blood

Signs and symptoms: Blood supply throughout vessels or


oxygen content of blood not
 Pain radiating to left
adequate to meet metabolic demands
shoulder and arm
 Dyspnea
 Pallor
 Sweating
 Faintness Myocardial ischemia
 Palpitations
 Dizziness
 Digestive disturbances
Pumping of the heart is reduced

Deprives ischemic cells of needed


oxygen and glucose

Cells converts to anaerobic


metabolism which leaves lactic acid as
a waste product

Lactic acid accumulates Pain in retrosternal area


radiating to the arms

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