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Author Topic:DMSODimethylsulphoxide(Read167934times)
JAKSUN Re:DMSO
Guest Dimethylsulphoxide
Reply#150on:August12,2010,
06:57:05AM
Quotefrom:GuardianonAugust12,2010,05:57:42AM
Iorderedminethroughthe"ValhomaCorporation"in
Oklahoma.Theyactuallyspecializeinhighqualityproductsfor
our2Dfriends...butIthoughttheirpriceswereprettygood,
andItrusttheirquality.Ihavefamilythathavebeenbuying
horsestufffromthemfor30+years.
http://www.dmso.com/
Checkouttheirprices...perhapsitmightbeworthitforallthe
Aussiestogettogetherandmakeabulkorderifyoucan'tget
DMSOlocally?
Theydon'tshipoverseas...butyawlcouldhaveitshippedfrom
thecompanyinOKtome,thenI'llreshipittoyawl,andyou
cansplityourorderupfromthere?
Justanidea?
Quotefrom:Bobo08onAugust12,2010,06:42:39AM
Igotminefromthis:
_http://www.horsesuppliesdirect.com.au/category63_1.htm
It'sthecheapestsourceofDMSOinOzthatIcouldfind
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1/3/2016 DMSODimethylsulphoxide
althoughit'sstillconsiderablymoreexpensivethanthoseinthe
US.
Thanksteam
Igotaquickreplyfromhttp://www.nikitanaturals.com/andhave
orderedfromthere.
Guardian,thatisagreatideathanksfortheofferforhelp. iam
notsureabouthowwewouldgetitthroughcustomsbut.
Bobo88,yesthatisanalternativeOnthatnote,Ireceivedthis
replyfromMalcolmR.HooperatHyperMEDNeuroRecovery
Australia.
Quote
wedonotsellDMSOdirectduetothefactthatAustTGAhas
notapproved[it]forhumanuse!Howeveryoucanalsobuy
DMSOmedicalgradequality99%inarollonformatatyou
localHorselandorStockandFeedoutlet!!DMSOiscommonly
usedasatopicalantiinflammatoryonanimals.
IthinkthatIwillgetmyDMSOonewayorother.Mypendulum
attunedtomyhigherSTOselfadvisesmethatIreallyneedthisstuff
inmywaragainstpersistantHCVinfection.Weshallwinthiswar,
onebattleatatime!
Thereisthisnoteonthehttp://www.nikitanaturals.com/site:
Quote
DMSO500ml(99.9%pure)70%+30%DoublePurifiedWater
R.T.U.inaamberglassbottle.
Whyaglassbottle?
DidyouknowDMSOisactuallyclassedasasolvent?However,
thisDMSOisnotIndustrialgrade,itisaPremium
Pharmaceuticalgrade.
AsDMSOisalsoaverypowerfulpenetrant/carrierIdon'twant
toriskcontaminationfromanyplasticsforeithertheuserorthe
recipient.
EventhoughDMSOisanontoxicproductmadefrom
leftoversofthepapermanufacturingprocess&theDMSO
ismadefromexactlythesameproduct,IdonotofferDMSO
forHumanUse.WhatyouchoosetouseDMSOforisentirely
yourchoice.
PS:DidyouknowthatDMSOcanalsobeusedtohelpstrike
yourgardenplantcuttingstoo?Didyoualsoknowthatwateris
asolventtoo?
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1/3/2016 DMSODimethylsulphoxide
LastEdit:August12,2010,07:06:25AMbyignite Logged
Guardian Re:DMSO
NoPMs Dimethylsulphoxide
Reply#151on:August12,2010,
05:09:50PM
Quotefrom:igniteonAugust12,2010,06:57:05AM
Thanksteam
Igotaquickreplyfromhttp://www.nikitanaturals.com/and
Posts:5,259
haveorderedfromthere.
Guardian,thatisagreatideathanksfortheofferforhelp.
iamnotsureabouthowwewouldgetitthroughcustomsbut.
Doyouknowalocalveterinarianwhowouldaccepttheshipmentfor
you?IdoubtCustomswouldquestionacaseof"horseliniment"
goingtoavet?
Justanideathatmighthelpagrouppurchaseinthefuture.Glad
youfoundasourcelocally
Logged
"Thisisnotatypicalchatordebateforum.Itisaresearchforumandthemembers
voluntarilyengageinspecificactivities,inspecificwaysforspecificpurposes."
Bud
ProdigalSon Re:DMSO
TheLivingForce Dimethylsulphoxide
Reply#152on:August14,2010,
01:08:52PM
Just5daysafterordering,aspromised,a16flozbottleof99.9%
DMSOanda5oztubof70%DMSO/30%AloeVeragelarrivedtoday
fromDMSO.net.Excellentservice.
Posts:2,603 Logged
'Youliterallypossesswithinyourconsciousnessprofileallthepowerthatexistswithinallof
creation!?!...Allyouneedtodoislearnhowtouseit,...(C's)
'...achallengethatprovokesfearfulresistanceinmeistheonethatImostneedtotake.'
(PepperFritz)
'learningisfun'(C's)
Niall Re:DMSO
SuperModerator Dimethylsulphoxide
Reply#153on:August14,2010,
05:52:20PM
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1/3/2016 DMSODimethylsulphoxide
Quotefrom:PsycheonMarch28,2010,04:34:59PM
Yeah,butbereadytohavean"asparagus"smellemanating
fromyourbody DMSOcanlastfordays,ittakes120hours
Posts:3,102 orsoinordertobeeliminatedfromthebody,sothatisanother
thingthatcanbeconsideredwhentakenorally.ButFWIW:
Quotefrom:MortonWalker
TheusualdosageofDMSOisonetotwoteaspoonsper
day.[...]
Certainfairskinnedpeoplesuchasthosewithredor
blondhairandblueeyesaremoresensitivetoDMSO.For
them,thetopical,oral,orintravenousconcentration
shouldbe50%orless,particularlyaroundthefaceand
neck."DMSO,Nature'sHealerbyDr.MortonWalker.
Wellthat'sinteresting.I'mfairskinnedandhavewonderinghowto
minimisetheimpactofthesmellI'mgivingoffaroundthehouse.I
can'tsmellanything,buttheothersfinditdownrightoffensive!They
havedescribeditas"likeopeningacanoftinnedsweetcorn" I'm
goingbacktoworksoonandamworriedthatIwon'tbeabletokeep
upmyweeklydoseofDMSOforfearofputtingoutmycolleagues.
I'llbegintakingsmalleramountsandseeifthathelps.
Logged
"Inrightknowledgethestudyofmanmustproceedonparallellineswiththestudyofthe
world,andthestudyoftheworldmustrunparallelwiththestudyofman."
G.I.Gurdjieff
Vulcan59 Re:DMSO
SuperModerator Dimethylsulphoxide
Reply#154on:August14,2010,
11:01:10PM
IhadcompletelyforgottenPsyche'sremarkaboutthe"asparagus
smell"andnowreadingyourremarkaboveKniall,remindedmethat
justtheotherday,myyoungestsaidthatIsmeltlike"popcorn"or
somethingthatshecouldn'tquitemakeout.Shedidn'tsayitwas
Posts:7,456 offensive.GuessitmustbetheDMSOthatIhavebeentaking
weekly.
Logged
"Toloveyoumustknow.Andtoknowistohavelight.Andtohavelightistolove.Andto
haveknowledgeistolove."
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1/3/2016 DMSODimethylsulphoxide
Gaby Re:DMSO
Ambassador Dimethylsulphoxide
Reply#155on:August14,2010,
11:10:59PM
Quotefrom:Vulcan59onAugust14,2010,11:01:10PM
IhadcompletelyforgottenPsyche'sremarkaboutthe
"asparagussmell"andnowreadingyourremarkaboveKniall,
Posts:6,074
remindedmethatjusttheotherday,myyoungestsaidthatI
smeltlike"popcorn"orsomethingthatshecouldn'tquitemake
out.Shedidn'tsayitwasoffensive.GuessitmustbetheDMSO
thatIhavebeentakingweekly.
LOL!Yeah,Idon'tlikethesmellatall!Butthatisjustme.
Logged
Hehidethmysoulinthecleftoftherock,Thatshadowsadry,thirstylandHehidethmylife
inthedepthsofHislove,AndcoversmetherewithHishand.
dant Re:DMSO
TheLivingForce Dimethylsulphoxide
Reply#156on:August14,2010,
11:16:58PM
Well,perhapsthereisthesilverliningthatthe
"garlicsmell"mightwardoffevilspirits?
Logged
Posts:2,234
Cs:Itisnotwhereyouare,butwhoyouare,andwhatyouSEE!
Thosewhohave Grandma:Believenoneofwhatyouhearandonlyhalfofwhatyousee
Eyes,Seethosewho
haveEars,Hear
Shijing Re:DMSO
TheLivingForce Dimethylsulphoxide
Reply#157on:August14,2010,
11:24:50PM
IstartedtakingDMSOafewweeksago,andItakeoneteaspoon
onceaweek.MyfamilynoticesasmellthefirsttwodaysafterItake
it,butthenitseemstoclearup.IfIsmokeatthesametime,it
seemstoexacerbateitandmakeitworse.Mydaughteraskedme
Posts:5,424 todaytopleasenotsmokeonthesetwodaysbecausethesmell
makeshergag
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1/3/2016 DMSODimethylsulphoxide
Onanothernote,I'mhappytosaythattakingDMSOinconjunction
withimplementingthesuggestionsthatweregiventomeearlierin
thisthreadisstartingtotakecareofmanyofmyremainingskin
problems.Acoupleareasarestillbeingstubborn,butI'venoticeda
lotofgeneralimprovement.
Added:UsingDMSOtopicallyalsohelpedimproveapatchofeczema
thatmywifehasbeenbotheredbyforquiteawhile.
LastEdit:August14,2010,11:32:54PMbyShijing Logged
"Givingbirthandnourishing,
Bearingyetnotpossessing,
Workingyetnottakingcredit,
Leadingyetnotdominating,
ThisisthePrimalVirtue."
LaoTsu,TaoTeChing(10)
Gaby Re:DMSO
Ambassador Dimethylsulphoxide
Reply#158on:August14,2010,
11:48:04PM
Quotefrom:ShijingonAugust14,2010,11:24:50PM
IstartedtakingDMSOafewweeksago,andItakeone
teaspoononceaweek.Myfamilynoticesasmellthefirsttwo
Posts:6,074 daysafterItakeit,butthenitseemstoclearup.IfIsmokeat
thesametime,itseemstoexacerbateitandmakeitworse.
Mydaughteraskedmetodaytopleasenotsmokeonthesetwo
daysbecausethesmellmakeshergag
Onanothernote,I'mhappytosaythattakingDMSOin
conjunctionwithimplementingthesuggestionsthatweregiven
tomeearlierinthisthreadisstartingtotakecareofmanyof
myremainingskinproblems.Acoupleareasarestillbeing
stubborn,butI'venoticedalotofgeneralimprovement.
Added:UsingDMSOtopicallyalsohelpedimproveapatchof
eczemathatmywifehasbeenbotheredbyforquiteawhile.
Thatisexcnews!Ithinkeverybodyshouldhaveasolutionof99.9%
DMSOaroundbecauseitbasicallyhasnoexpirydateanditcan
becomereallyhandy.Itreallydoeshelp!
Youdon'tsmellitwhenyoutakeit,sothatisthegoodthing.Butif
youarenotwellhydrated,thesmellismuchmorepowerfulfor
others.SomakesuretodrinkenoughwaterwhiletakingDMSO .
Logged
Hehidethmysoulinthecleftoftherock,Thatshadowsadry,thirstylandHehidethmylife
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1/3/2016 DMSODimethylsulphoxide
inthedepthsofHislove,AndcoversmetherewithHishand.
Shijing Re:DMSO
TheLivingForce Dimethylsulphoxide
Reply#159on:August15,2010,
12:00:33AM
Quotefrom:PsycheonAugust14,2010,11:48:04PM
Youdon'tsmellitwhenyoutakeit,sothatisthegoodthing.
Butifyouarenotwellhydrated,thesmellismuchmore
Posts:5,424
powerfulforothers.Somakesuretodrinkenoughwaterwhile
takingDMSO .
OK,thanksforthetip,PsycheIdon'treallypayattentiontomy
hydrationlevels(morethanusual)whenItaketheDMSO,soIwill
startpayingattentiontothatnow!
Logged
"Givingbirthandnourishing,
Bearingyetnotpossessing,
Workingyetnottakingcredit,
Leadingyetnotdominating,
ThisisthePrimalVirtue."
LaoTsu,TaoTeChing(10)
Pete Re:DMSO
TheLivingForce Dimethylsulphoxide
Reply#160on:August15,2010,
01:14:16AM
Quotefrom:ShijingonAugust14,2010,11:24:50PM
IstartedtakingDMSOafewweeksago,andItakeone
teaspoononceaweek.Myfamilynoticesasmellthefirsttwo
Posts:2,010 daysafterItakeit,butthenitseemstoclearup.IfIsmokeat
thesametime,itseemstoexacerbateitandmakeitworse.
Mydaughteraskedmetodaytopleasenotsmokeonthesetwo
daysbecausethesmellmakeshergag
Onanothernote,I'mhappytosaythattakingDMSOin
conjunctionwithimplementingthesuggestionsthatweregiven
tomeearlierinthisthreadisstartingtotakecareofmanyof
myremainingskinproblems.Acoupleareasarestillbeing
stubborn,butI'venoticedalotofgeneralimprovement.
Added:UsingDMSOtopicallyalsohelpedimproveapatchof
eczemathatmywifehasbeenbotheredbyforquiteawhile.
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1/3/2016 DMSODimethylsulphoxide
Lol.Thisisthesamereactionmyfamilyhasaswell.Itakea
teaspoononmydaysoffandbythetimeIgetbacktoworkitseems
tobegone.Twodaysseemstodoitformetoo.Thecomboof
smokingatthesametimeisinteresting,maybeI'lltonedownmy
smokingforthetwodaysandseewhathappens.
IhadneverthoughtaboutusingittopicallybeforebutI'mgonna
giveitashotonmynextdayoffandseewhathappens.Istillhavea
littlerashthatseemstocomeandgo.
Logged
MywishtoBEisacosmicwish,andmybeingneedstosituateitselfinaworldofforces.
ThereisacosmicneedforthenewbeingthatIcouldbecome.JeanneDeSalzmann
3DStudent Re:DMSO
TheLivingForce Dimethylsulphoxide
Reply#161on:August15,2010,
08:51:20AM
IhappentohavefinallyusedmyDMSOtooonFridaynightbefore
sleeping.Itookateaspoonwithacupofwater,followedby2more
cupsofwater.Itreallytastednasty ,likeeatingarottenegg
Posts:2,653
extract .MymomsaidIsmelledreallybadandthatshecould
smellmewhenIwokeuptogotothebathroominthemiddleofthe
night.
ButwhenIwokeupSaturdayshewastheonlyonewhonoticedthe
smell.Mysister,whohasasensitivenoseaswell,didn'tsay
anything.SoI'mguessingitworeoffalittlewhileIslept.Imade
foodsomaybethatwasmaskingthesmelltoo.
Imighttryputtingitonmyhands,whicharereallydryandIthink
mighthaveeczema.Ijustneedtofindasuitablecontainertomixup
asolutionin.
Logged
Gaby Re:DMSO
Ambassador Dimethylsulphoxide
Reply#162on:August17,2010,
12:19:31PM
Idon'tthinkwehavesharedthisoneherejustyet.
Quote
Posts:6,074
http://healthnews.benabraham.com/html/fountain_of_youth_
_nature_s_h.html
Chapter6
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1/3/2016 DMSODimethylsulphoxide
DMSOThePersecutedDrug
Dr.StanleyJacob
ANewYorkTimeseditorialonApril3,1965calledDMSOthe
closestthingtoawonderdrugproducedinthe1960's.There
wasagreatdealofpublicityandcontroversyaboutDMSOin
the1960'sand1970's.OnMarch23andJuly6,1980,Mike
Wallacehadtwo60MinutesprogramsonDMSO.
ThePersecutedDrugTheStoryofDMSO(fromwhichthetitle
ofthischapterwasborrowed)waswrittenin1972bythelate
PatMcGradySr.Intheopeningofhisbookhewrote:
Thisisthestoryofadrugwhichwasglorifiedbrieflyashaving
almostpanaceanpropertiesfortheailmentsofmanandbeast
anddiseasesofplantlifeandthenwasbanishedbyhighUnited
Statesauthorities(theFDA)asdangerousandwithoutmerit.
Thisisalsothestoryofamildmanneredscientist(DrStanley
Jacob)whochallengedthelawanddefiedtheofficialsandtheir
policeinasoulsearingstruggletomakethedrugavailable
whereverthereislife.
ThedrugisknownasDMSO,ordimethylsulfoxide(aliquid).It
hasbeenchampionedbyreputablephysiciansascapableof
healingorpalliatingmanyailments.Ithasbeenrepresentedas
a"wonderdrug"ora"miracledrug".Itisabundantitcanbe
extractedfromsuchsourcesascoal,oil,ormostcommonly
lignin,thematerialnatureusestocementcellstogetherin
treesitischeapitismostoftenadministeredbysimply
dabbingitontheskin,and,aloneorasacarrierforother
drugs,whichDMSOoftenpotentiates,itpenetratestheskinto
enterthebloodstreamwhereitisbornetoallpartsofthe
body.
Scientistscontendthatthe(thousandsof)paperspublishedin
professionaljournalsrefutevirtuallyalltheFDAcharges.
OnJuly31.1980,SenatorMarkHatfieldofOregontestifiedata
hearingofSenatorEdwardKennedy'ssubcommitteeonhealth:
IcannotmakeanabsolutestatementthatDMSOisindeedthe
wonderdrugofourcenturybuteverybitofevidenceI
encounterreinforcesthepremisethatitis.After1,200scientific
publicationsonthemeritsofDMSO,afterinternational
symposiainGermany,theU.S.,andAustriaallconcluding
thatDMSOissafeandeffectiveafterthreeseparate
pharmaceuticalfirmshavesubmittedfornewdrugapplications
totheFDA(allrejected),DMSOisstillnotavailableto
Americans,althoughitisavailableinmanyothercountries.I
haveurgedtheSenatetosupportmylegislation(toapprove
DMSO)onbehalfofallAmericanswhoaresufferingfrom
diseasesuntreatablebyanyotherknownsubstanceandthose
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1/3/2016 DMSODimethylsulphoxide
whomayhaveneedofthisdruginthefuture.
StrokesarethethirdbiggestkillerintheU.S.,causingover
150,000deathsayear.Theyarealso"theprimarycauseof
seriousdisabilities",U.S.NewsreportedonMarch30,1998,
"leaving3,000,000peopleannuallyunabletoworkortakecare
ofthemselves".Ifgivensoonafterastroke,DMSO,oneofthe
world'sgreatestsolvents,hasbeenshowntodissolvetheclot
thatcausesthestroke,thusrestoringcirculationandavoiding
paralysis.Howsoon?Dr.StanleyJacobsayswithinthefirstfew
hoursisbestandintravenouslyisbetterthanoral,butoral
workstoo.OnceDMSOgetsintothebodyeitherdaubedonthe
skin,givenI.V.,orbymouth,itpermeatesthebodyand
crossesthebrainbarricr,soeventakenorallyitcanimprove
circulation.Onemanwhohadastrokeat7:30AMrefusedtogo
tothehospitaluntilafterhiswifehadspokenwithDr.Stanley
Jacob,whichdidn'thappenuntil6:30PM.Startingat7PMthe
dayofthestroke,shegavehimoneounceof50%DMSOina
littleorangejuiceevery15minutesfortwohoursandthen
everyhalfhourfortwohours.Thenextday,herhusbandwas
betterandsoonreturnedtonormal.Asubstancethatcanstop
astrokeasit'shappeningissomethingmanymightwantin
theirhomemedicinechest.
NeurosurgeonDr.JackdeIaTorreisprofessorofphysiologyand
neurosurgeryattheUniversityofNewMexicoinAlbuquerque.
HeandDr.JacobbelievethatDMSOshouldbeinevery
ambulanceandemergencyroomsoastostartgivingit
intravenouslytostrokevictimsintheambulanceassoonas
pickedupor,atthelatest,assoonasthepatientarrivesatan
emergencyroom.Ifsuchweretheestablishedpractice,the
numberofpeopledyingorincapacitatedfromstrokeswould
plummet.
Notonlywouldmanylivesbesaved,butalsotheawfulhardship
ofparalysisorlossofspeechmightbeprevented.Astroke,
evensurvived,canoftenbringaperson'seffectivelifetoan
abrupthalt.Thesavingstothemedicalsystemwouldbe
astronomical.Thecostoftheproduct:pharmaceuticalgrade
DMSOretailsat$3040agallon.
DMSO'sabilitytostopstrokesisonlyitsmostdramaticand
unappreciatedattribute,andtheonewhichwouldsavethe
mostlives,themostsuffering,andthemostmoney.
AclosesecondisDMSO'seffectivenesswithheadand/orspinal
cordinjuries.Dr.delaTorrestatestherearearound1,000,000
headinjurieseachyear.Oftheseabout500,000are
hospitalizedwith5080,000beingsevere,another50,000
moderate,andtherestlessserious.Ofthe50,000severe,60
70%eitherdieorhaveseverecontinuingneurologicalproblems
(i.e.,paralysis),amultibilliondollarayearexpense.
ResearchinanimalsindicatestoDr.delaTorrethatif
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ChristopherReevehadbeengivenDMSOintravenously
immediatelyafterhisaccident,hemightneverhavebeen
paralyzed.Dr.JacobfirsthasgivenDMSOintravenouslyto
peoplewhowerealreadyparalyzedparaplegicsandlittleby
littletheyregaineduseoflimbs.Oneman,quadraplegic,
recoveredenoughtogothroughcollegeandthentoworkina
bank.
ArecentstudyinTurkeycombinedDMSOwithfructose
diphosphate.In20patientswithheadinjuries,thecombination
provedveryeffectiveindecreasingintracranialpressure.Dela
Tonedeclaresthatinhisexperience,nothingreduces
intracranialpressurefasterthanDMSO.Animaltestsinthe
1960'sandthenhumantestsonprisonersin1967
demonstratedthatDMSOisnontoxic,indeed,lesstoxicthan
aspirin.
InDr.delaTorre'stestsondogs,injuriesthatnormallywould
havecausedparalysishealedcompletelywhenDMSOwasgiven.
ThemechanismsofactionbyDMSOaremuchthesameinboth
strokesandspinalcordinjuries.InDMSO,Nature'sHealer,Dr.
MortonWalkersummarizesDr.deIaTorre'stestimonyto
Congressin1980onDMSO'smethodology,basedonhis
researchwiththedrugwhichbeganin1971:
DMSOpermitsandpromotesbetterbloodflowbydilatingblood
vessels,thusincreasingthedeliveryofoxygenandbyreducing
bloodplateletstickiness.
BecauseDMSOdilatesbloodvessels,carotidarterybloodflowto
thebrainincreasesafterDMSOisgivenintravenously.
AfterI.V.administrationofDMSO,thereisanelevationinthe
amountofspinalcordbloodflowtotheregionoftrauma.One
ofthefirstthingsthathappensafterspinalcordtraumaisthat
areductionofoxygenandbloodflowsetsin,inasmuchasthe
bloodvesselsconstrictorshutdown...Withoutsometreatment,
thetissueswells.Eventually,thisleadstoparalysis.Ina
cerebralstroke,theanimalwilleitherbecomecomatoseor
lethargicordie.WithDMSOinfusionimmediatelyafterinjury
(orstroke)allthisisprevented.
ThirtyminutesaftergivingDMSOI.V.,thereisanincreasein
theflowofcortisone,anaturalbodysubstancewhichhelpsfight
offeffectsoftrauma,eventhoughtheanimalbeingtestedhad
alreadystoppedsecretingcortisone.
DMSOcrossesthebloodbrainbarrier,entersthebrain,picks
upwaterfromaninjury,andrushesitoutofthesystem,thus
relievingintracranialpressure.
Inanimaltests,theanimalsarebroughttoapointwherethe
electroencephalogramreadingbecomesflat,justpreceding
braindeath...TenminutesafterinjectionofDMSO,the
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electroencephalogramreturnsandthebrainbecomesactive
again.
Dr.Walkeradds,"DMSOtendstoprotectnervecells...following
injury.Itprovidesbetterprotectionthananyothertreatments.
Scientistshaveverifiedthisbyobservationwiththeelectron
microscopeandthelightmicroscope.ThusDMSOpreventsthe
paralysisthatmayensuefollowingtraumaitaltersthesevere
effectsseenafterabrainstroke".
Drs.JacobanddelaTonebelievethatDMSOisthetreatment
ofchoiceinstrokesandnotethatdelaTorre'sworkhasbeen
confirmedbyatleastthreedifferentgroupsofinvestigatorsin
otherpartsofthecountry.Theyalsobelievethatthe
combinationofDMSOwithfructosedisphosphateshouldbethe
treatmentofchoiceinspinalcordandclosedheadinjuries,
wherethefructosediphosphateprovidesenergytohelprestore
damagedtissue.
DreadedAlzheimer'sdiseasewillalsobeanotherarea,they
expect,wherethecombinationofDMSOandfructose
diphosphate(patentedbyDr.DeLaTorre)willbecomethe
treatmentofchoice,thefructosediphosphatebeingcarried
acrossthebloodbrainbarrierbytheDMSOtohelprestore
energytoadeterioratingbrain.
Inexperimentswithrats,Dr.delaTorrehascombinedLdopa
withDMSO,whichcarriestheLdopaacrossthebloodbrain
barrierintothebrainwhereitbecomesdopamineandturnsoff
thepartofthebrainwhichcausesthetremblingandother
symptomsofParkinson's.
WhilestrokesarethethirdlargestkillerintheUS,heartattacks
killthemostpeopleabout3/4ofamillionperyear.
RememberingDMSO'sabilitytodilatebloodvesselsand
improvebloodflow,itisnotsurprisingthatSouthAmerican
researchindicatesthatDMSOiseffectiveinheartattacksand
anginapromptuseofitinheartattackshasbeencreditedwith
preventingdamagetoheartmuscle.Reportingthisinhisbook,
Dr.MortonWalkersays,"Thereisacryingneedforresearchon
theuseofmassivedosesofDMSO(2gramsperkilogramof
bodyweight)inthetreatmentofheartattacks".
IfDMSOisthatgood,thenwhereisit?Whycan'twegetit?
Whyisn'titused?Thatisanotherstory,andasadonewhen
onethinksofthesufferingthatcouldhavebeenrelievedor
avoidedifresearchinDMSOhadnotbeenstifledbytheFDA.
Butthisstoryisn'toveryet.DMSO,inadditiontobeingavery
safeandeffectivenontoxicdrug,isalsoacommercialsolvent
usedinmanyindustrialprocesses.UnlikeKoch,Rife,or
Krebiozen,itcannotbestampedoutsinceitcaneasilybe
boughtinmanyhardwarestores.EveryoneinvolvedinDMSO
researchisupsetatprivateuseofcommercialgradeDMSOfor
anymedicalpurpose,andwithgoodreasonsinceitcontains
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1/3/2016 DMSODimethylsulphoxide
impurities.However,peoplesufferingfromarthritisorother
painshavetakenmattersintotheirownhands.Thereisalarge
undergroundmarketinthesubstance,andpharmaceutical
gradecanfrequentlybefound,notsoldforhealingpurposes,of
course.Cuttinginhalforlessthetimetohealsprains,many
athletescountonit.It'slegalforveterinarianstouseindogs,
cats,andhorses.
Itshouldhavebeenotherwise.DMSOshouldbeaprescription
drugavailabletodoctorsforgeneraluse,asitisinEurope.
Instead,itisapprovedbytheFDAforuseinhumansinjust
oneraredisease,apainfulbladderconditioncalledinterstitial
cystitis.ThehealthusesofDMSOmakeitoneofthemost
versatilesubstanceseverfoundawonderdrugindeed.Itwas
discoveredin1866byRussianscientistDrAlexanderSaytzeff,
whonotedinapaperhepublishedinaGermanmedicaljournal
thefollowingyearthatitwoulddissolvevirtuallyanything
combinedwithit.
Enteringthebodyeitherpaintedontheskin,takenorally,or
viaI.V.,DMSOrapidlypenetratesthecellsandcleansthemof
toxins,adesirablemechanismwhichmayexplainmuchofits
versatility.
AthletesstillknowaboutDMSO.JuneJones,oncequarterback
andlatercoachoftheAtlantaFalconsprofootballteam,knows
ofDMSO.Hiscareeralmostdidn'thappen,hetoldtheHouseof
RepresentativesCommitteeonAgingin1980,whichwas
investigatingwhytheFDAwasstilltellingpeoplethatDMSO
wasdangerous.Withabursitiscalcificationinhisright
shoulder,hecouldhardlylifthisarm,letalonethrowafootball.
FromOregon,hewasawareofDMSOandofDr.StanleyJacob,
andhadusedDMSOforsprains,likethousandsofothers.Sohe
wenttoDr.Jacob,whogavehimashotofDMSOinthe
shoulderandtoldhimthatthecalcificationmightdisappearif
heusedDMSQfor30daysstraight.Hefollowedinstructions
anditdiddisappear.TheFDAstillhasnotapprovedDMSOfor
sportsmedicine.
FormerOregonGovernorTomMcCallknowsaboutDMSO.
Strickensuddenlybybursitisin1963,twodaubingsofDMSO
onhisshoulderputanendtotheproblemastheDMSO
dissolvedthecalcificationthatcausedthepainfulcondition.
Abyproductofwoodpulpproduction,this"treejuice"asthe
latePatMcGradycalledit,helpssomanyhumanproblemsthat
oneisremindedoftheBookofGenesis,whereGodsaidthatHe
hadplacedontheEarthsomethingforeveryhumancondition.
Ittakesusawhiletofiguresomeofthemout,andtheneven
longertoclearawaythemanmadeobstaclestotheiruse.
In1960,RobertHerschler,chemistandchiefofresearchat
CrownZellerbach,ahugepaperandpulpmanufacturernear
Portland,foundaninexpensivewaytoproduceDMSOasa
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byproductofthepulpindustry.Henotedthatthechemicalhad
aremarkableabilitytopenetratetheskinandspread
throughoutthebodyveryquickly.Byitselfnottoxic,Herschler
learnedthatwhenDMSOisputtogetherwithsomethingtoxic,
therecanbeproblemsifthecombinationisputontheskinor
ingested.SinceDMSOisasolvent,heandanassistant
regularlywashedtheirhandsinituntilthedayhedidsoafter
havinghandledpesticidesandbecamequitesick.
Tothisday,aftermanyhundredsofthousands,probablyeven
millionsofpeoplehavebeentreatedwithDMSOandthousands
ofstudieshavebeendone,thisistheonlydangerassociated
withDMSO,bewareofwhatyoumixitwith.
RealizingtherecouldbemedicalpossibilitiesinDMSO,in1961
Herschlergotpermissionfromhissuperiorstocheckwiththe
UniversityofOregonMedicalSchoolinPortland,andwas
introducedtoStanleyJacob.Themeetingmademedical
history.Dr.StanleyJacob,brilliantgraduate(insurgery)of
HarvardMedicalSchoolandprofessorofsurgeryonthefaculty
oftheUniversityofOregonMedicalSchool,hadpublished40
papersinprestigiousmedicaljournalsbeforeheheardof
DMSO.Holderofnumerousacademicandprofessionalhonors,
hewasalreadyapioneer.Hearttransplantswerestillthestuff
ofsciencefictionin1961,buteventhenJacobandhis
associatesweregettingpuppyheartstobeatinmaturedogsfor
severaldays,andhewaslookingforwaystopreservethem.He
founditinDMSO,whichisnowusedworldwideforstorageof
organtransplants.
AfterhearingaboutDMSOfromRobertHerschler,Jacobpainted
someonhisarmandwithinmomentsbecameawareofits
oysterishtasteinhismouth.Heknewthatthismeantthatthe
substancehadnotonlyquicklypenetratedhisskinbutthatit
hadgoneintohisbloodstreamandpermeatedhisentire
system.Herealizedthatthiscouldmeananentirelynew
medicalprinciplefordeliveringmedicines.AsPatMcGradyput
it,DMSO"wastochangeStanleyJacob'slifeandwhathe
learnedaboutitwastochangethelivesofmanyothersandhad
thecapacitytochangemanymore".
Dr.JacobandHerschlerdevisednumerousexperiments,one
showingthatmicewhichhadsustainedburnsweremore
comfortableafterbeingdaubedwithDMSO.Herschlersoon
profitedfromthisknowledge.Afteranaccidentalchemicalburn
onhishands,arms,andforehead,hecalledJacob."Apply
DMSOononesideandseewhathappens",Jacobtoldhim.
Herschlercalledhimbackin15minutes,"Thepainstopped.
NowI'mgoingtodotheotherside".Afewweekslater,oneof
Herschler'sassistantssprainedanankle.In15minutesafter
DMSOwasapplied,thepainwasgoneandin30minutesthe
swellingaswell.
SomeonecomplainedtoDr.Jacobofasplittingheadacheand
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gavehimpermissiontoapplysomeDMSOafterhearingofits
capabilities.Theheadachewasgoneinminutes,camebackin
fourhours,andleftforgoodafterDMSOwasappliedasecond
time.Usedforonepurpose,sometimesitdidanotherputona
coldsore,withinafewhoursitclearedupawoman'ssinusitis.
AwomanwhohadhadastrokefoundafterDMSOwaspainted
onherpainfuljawthatshecouldnowwritewithherparalyzed
handandcouldwalkbetter.Dr.Jacobfoundthatitcouldalso
suppressinflammation.
Thetreejuiceworkedintrees,too.Witheredoldappletrees
becameyouthfulandfullofleavesafterDMSOwasinjected
underthebark.
ApplyingDMSOwhereithurttoasixyearoldwastedfrom
rheumatoidarthritis,inahalfhourthechildcouldmoveher
shoulderandturnherheadforthefirsttimeintwoyears.
Persuadedtotrywalking,shemanagedafewstepsandthen
burstintotears."Whyareyoucrying?"DrJacobaskedher.
"Becauseitdoesn'thurtanymore",shereplied.
DMSOwasverycheap,HerschlertoldJacob."Icouldpipeit
downhere.Youcouldhaveitbythebarrelorthetank!"
Impressedwithwhathewasseeingbutwantingsomeone
skepticaltoplaydevil'sadvocate,Dr.JacobsoughtoutDr.
EdwardRosenbaum,aphysicianinprivatepracticeinPortland.
Rosenbaumdidnotpaymuchattentionuntilapatientwith
severebursitisstartedlaughing,proclaiminghispaingone15
minutesafterhisshoulderwaspaintedwithDMSO.Another
colleaguepoopooedDMSOuntilafteroneofhisbursititis
patientshadrecoveredviathechemical.Hethendeclaredthat
obviouslythecasemusthavebeenmisdiagnosedandaskedif
heshouldbuysomestockinCrownZellerbach(whichproduced
DMSO).
In1963,Dr.JacobandRobertHerschlersubmittedtwopapers
onDMSOtomedicaljournals.Beforethearticleswere
published,thepressbroketheDMSOstoryonDecember10,
1963whenCrownZellerbachandtheUniversityofOregonfiled
atthestatecapitalacontractinwhichtheybecamepartnersin
thepatentedusesofDMSO.Thepatentswererequestedinthe
namesofHerschlerandJacobandspelledoutthemajorresults
seenfromDMSOresearch,sothenewswasnowpublic.On
December18,theNewYorkTimescarriedthestoryonitsfront
pageandCrownZellerbach'sstockjumped10%.
TheJanuaryandMarch1964issuesofNorthwestMedicine
publishedarticlesbyJacobandRosenbaumonbursitisand
arthritis.ThisgavesomelegitimizationtoDMSOinscientific
circlesbutstirredupanimosityaswellamongthosewho
resentedhearingaboutDMSOfirstinthepopularpress.When
JacobpresentedhisworktotheUniversityofOregonMedical
Schoolfaculty,therewereafewjeersof"liar,charlatan,quack".
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Itwashardformanytobelievethatsomethingasversatileas
DMSOcouldexist.Dr.Jacobsentamemodescribing20ofhis
casestohisimmediatesuperiorandfriend,whorepliedwitha
notesaying"ThissmacksofAndrewIvy!"Afewmonthslater,
thesamefriendtoldJacobthathehaddreamedtheprevious
nightthattheDMSOaffairhadbeenturnedovertothe
NationalAcademyofSciences.ThenStanJacobremembered
hisfather'sdream.Aweekbeforehedied,hisfathersaidhe
haddreamedthatStanwouldfindsomewonderfulchemical
fromwood,andpeopleallovertheworldwouldbeholdingout
theirhandsforit!
Thatdreamwascomingtrue.Itwouldbeeightyearsbeforehis
colleague'sdreamcametrue,andalotoffurwouldflybefore
then.
In1965Merck,Syntex,andSquibbPharmaceuticalall
submittedNewDrugApplications(NDA's)totheFDA,stating
thatDMSOwasreadytobeaprescriptiondrug.TheFDA
turnedallofthemdown.InJuly1965,thefirstinternational
symposiumonDMSOwasheldinBerlin.
WhathappenedtoDMSO(andKrebiozenbeforeit)ishardto
understandwithoutrecallingthecrisisatmosphereintheearly
1960'ssurroundingthesleepingmedicationthalidomide.The
requestforapprovalofthedrugwasassignedtoDr.Frances
Kelsey,ChiefoftheInvestigationalDrugBranch.Sheprocessed
theapplicationbydoingnothingatallwithitforabouttwo
years.DuringthattimeanumberofbabieswereborninEurope
withoutarmsorotherlimbsandthecausewastracedbackto
thalidomide.SinceDr.Kelseyhadnotprocessedtheapplication
andthus"saved"Americansfromthedrug,shegotamedal
fromPresidentKennedy,(Thetruth,Dr.MortonWalkertellsin
DMSO,Nature'sHealer,wassomewhatdifferent:1,200doctors
intheU.S.hadaccesstothalidomidethroughtheFDAand
therewerethalidomidebabiesintheU.S.Somewerechildren
ofdoctors.)
AfterDr.Kelseywashonored,everyotherFDAbureaucratwas
onthelookoutforwaystoshowvigilanceandforthingstostop.
OnFebruary8,1981,RobertHerschlerappearedonDavid
Hartmann'sGoodMorningAmericashowandtoldhishost
aboutDMSO'sreceptionattheFDA."Theycomplainedbitterly
in1964thatDMSOwasbothacommercialsolventandadrug.
Theycouldnotcontrolit.FrancesKelseyraisedherhandsand
said'WesimplycannotcopewithaproductlikeDMSO.We
envisionhundredsof(newdrug)applicationscominginandwe
simplydon'thavebudgetorstaff'.Afterthat,theFDAtooka
hardlineonDMSO".
Rememberingthalidomide,theFDAapparentlywaslookingfor
thingstostop,andfounditschanceinlate1965.TheFDA
learnedthattestsinrabbits,dogs,andpigs(butnothumans)
hadshownsomeproblems.WhenquantitiesofDMSOequalto
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abouttentimesthemaximumhumandose(i.e.,equalto350
gramsadayfora175poundman)weregiveneverydayovera
periodofsixmonths,slightchangesinthelensesofthe
animals'eyeswouldresult,enoughtoproduceaslight
nearsightedness.Thelenschangeswerenotenoughtocause
dogsdifficultywhenrunningtheydidn'tbumpintothings
andinsomecases,thechangesdisappearedafterthemassive
DMSOdoseswerestopped.Innotestatthattimeorsincehas
DMSOevercausedcataracts,eitherinanimalsorinhumans.
TheFDAdecidedthatDMSOwasthedangerousdrugitwas
lookingfor.ThefirstDr.Jacobandhiscolleaguesknewofthe
animaltestswasonNovember10,1965.Onthatcrucialdate,
theFDAsentnoticestoallthedrugcompaniesinvolvedin
DMSOresearch(Squibb,Syntex,Merck)that"administrationof
thedrugmustbediscontinuedandthedrugrecalledfromall
clinicalinvestigation".Inaddition,theFDAputoutaseriesof
pressreleasescarriedbymediaallovertheworldwarningof
theblindingeffectsofDMSO,andleadingpeopletobelievethat
DMSOcausedcataracts.Butnoanimalswereblinded,andthe
FDAknewthat.The"spin"wasdesignedtoshowthatonce
againtheFDAhad"saved"us.
Thusresearchwasstoppedinitstracksonadrugwhichwas
stoppingpain(whennothingelsecould)frombursitis,arthritis
(includingrheumatoid),andgout,whichwascuttingatleastin
halfthetimeneededforrecoveryfromathleticinjuries,and
whichhadevensavedaboy'slifewhenhisneckwasbrokenin
anaccident.DMSOpreventsswellingandrapidinjectionofthe
chemicalsoonaftertheaccidentpreventedtheswellingwhich
otherwisewouldhavechokedhimtodeath.
Drs.JacobandRosenbaumandRobertHerschlerhadconstantly
beenlookingforanyindicationofDMSOtoxicityandhadfound
none.Learningoftheanimaldata,asquicklyascouldbe
arrangedtheybroughtpastandcurrentpatientstothe
ophthalmologistsattheUniversityofOregontolookforlens
changesofanysort.Aftermonthsoftesting,absolutelynolens
problemswerefound.Tothecontrary,severalreportedthey
couldseebetterafterusingDMSO(onotherpartsofthebody).
Sotheordertostopresearchhadbeenbasedonaninaccurate
pretext.
InformedofthetestsbyDr.Jacobandothersshowingthat
humanswerenotexperiencingthesamelenschangesasthe
threeanimalspecies,theFDAatfirstseemedtohavesecond
thoughts.Hadtheyoverreacted?
AnFDAlesseagertoplay"gotcha"mighthavehandledthe
situationquitedifferently.Uponreceivingtheinitiallensdata,
theymighthaveimmediatelyinformedthedrugcompaniesand
Dr.Jacobandaskedthemurgentlytocheckifanyhumanswere
experiencingthesameproblemsastheanimals,whichiswhat
Jacobandhisteamdidanyway,beingresponsiblescientists.
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Or,afteritsfirstrelease,theFDAcouldhaveannouncedthatit
wasgoodtobevigilantbutthatDMS0wasnotcausingthe
sameresultsinhumansashadbeenseeninsomeanimals.It
couldthenhavesaidquietlytotheresearchers,"watchvery
carefullyforhumanproblemsbecauseifsuchoccur,DMSOwill
havetobewithdrawn".IftheFDAhaddonethat,everybody
wouldhavebeenhappy.TheFDAwouldhaveshownits
vigilancefordrugdangers,whichiswhatit'ssupposedtodo.
Andnobodywouldwanttoworkwithamedicinethatcaused
eyeproblems.
Finally,FDAadoptedanalltoohumanattitudetheydidnot
wanttoadmittheyhadmadeamistake.Theyapparently
arrivedatadecisionthatDMSOmustbeanotherthalidomide
andthatifFDAagentsonlylookedhardenough,theywould
findtheevidenceandallwouldbeheroes.Ifithadturnedout
thatway,theywouldhavebeen,butitdidn't.
In1965,theJAMAprintedanarticlebyDr.JacobonDMSO.
Interestingly,histroublehasonlybeenwiththeFDA,notthe
AMA.TheJAMAhasneverturneddownoneofhisarticles,and
heregularlywritesitsbookreviews.
BeforefreedominDMSOresearchwaswithdrawn,orthopedic
surgeonDr.ForrestRiordansawDMSOsaveafrostbite
patient'slimbs.Arrivinghomeaftermidnightona15degreeF
night,a59yearoldwomanslippedontheiceoutsideher
garage,hitherhead,lostconsciousness,andlaybesidehercar
forsixhours.BythetimeDr.Riordansawher,herfeetand
handswerepurple,andherfingerswereturningblack.Having
alreadytreated50patientswithDMSOandbeingawareofits
useinpreservingandrestoringtissue,Dr.Riordandecidedto
giveitatry.PatMcGradydescribeswhathappened."The
questionwas,wouldDMSOgivenewlifetothelady'sdying
fingersandrestorebloodtoherlimbs?Tenminutesafter
RiordanhadswabbedDMSOonthepatient'shandsandlower
legs,thetreatedareasreddenedwiththereturnofblood.The
DMSOodorwasonherbreath,showingthatthedrugwas
permeatingthewoman'ssystem.Onthesecondday,blisters
hadpoppedoutonthefrozenareasandthateveningshe
regainedconsciousness...Onthethirdday,sensationbegan
returningtosomeofthetoesandlaterthetipsofthefingers
begantohavefeelingagain.ByDaySeven,shewasabletoflex
herjoints.Foranentiremonth,thepatientwassloshed,
swabbed,anddabbedwithDMSO.Almostagallonofitwas
used,butsideeffectsamountedonlytoanoccasionalrash,abit
ofburninganditching...ByDayFourteen,itwasclearthatall
tissueswereviable...Riordanconcludedthatthedrugshouldbe
appliedwithin12hoursoffreezingandthat24hoursmaymark
thecriticalpointinreversingdamagetotheinvolvedblood
vessels".
Thisisthesortofexperimentationthatwasgoingonbefore
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FDAhaltedDMSOresearch,afreedomto"tryitsincenothing
elseisworking"approach,whichinthiscaseprobablysavedone
ladyherlifeandcertainlyherfourlimbs.Howmanyothers
todaymighthavesavedlimbsiftheknowledgeofthisonecase
hadbeenbroadcastandDMSO'suseencouragedinsteadof
discouraged?
PlanninghadbeengoingonforsometimeforaSymposiumon
DMSOtobeheldinMarch1966attheNewYorkAcademyof
Sciences.OnNovember9,1965,atopFDAofficialtoldDr.
JacobthathehaditongoodauthoritythattheSymposium
wouldneverbeheld,notexplainingthathewouldannouncethe
DMSObanthenextday.
Hewaswrong.Dr.ChaunceyLeakeoftheUniversityof
CaliforniaMedicalCenter,whohadagreedtochairthe
Symposium,toldDeanBaird,Dr.Jacob'ssuperioratthe
MedicalSchool,thathe'dbeenaskedtodropplansforthe
symposiumonthegroundsthatitwouldbeembarrassingfor
boththedrugcompaniesandtheFDA.Bairdreplied"Chauncey,
whenhaveyouandIasdeansandeducatorseverletpoliticalor
economicconsiderationscompromisethesearchforscientific
truth?"BairdalsotoldJacobthatCrownZellerbach,unusedto
suchcontroversy,hadurgedhimtocalloffthesymposium.The
NewYorkAcademyofSciences,alarge,prestigiousorganization
foundedin1828withover25,000members,madetheir
displeasureatpoliticalinterferenceevidentbyputtingupthe
$60,000costofthemeetingwhenpharmaceuticalcompanies
refusedtodoso.
UndeterredbytheFDA,over1,000peoplefromtheworld
scientificcommunitywereinattendancewhenthesymposium
openedattheWaldorfAstoriaonMarch14,1966,togoonfor
threedays.WhenoneoftheFDAofficialsspoke,stating"this
symposiumisameasureofthefreedomofinvestigation..,
prevailinginthiscountry",peoplewonderedifhewasbeing
ironic.
ThepaperspresentedshowedgreatenthusiasmforDMSOand
itsunusualmedicalproperties.Itsabilitytoprotectlivingcells
fromcoldandradiationwasdiscussed,anditslackoftoxicity
wasstressed.PatMcGradywhoattended,wrote,"thestudies
coveredaspectrumofdiseasesprobablyfargreaterthanany
everbeforeconsideredinrelationtoasingledrug".
McGradycalledspecialattentiontoanextraordinarypaper
presentedbyDr.EduardoRamirezandDr.SegisfredoLuzaof
theAyetanoHerediaUniversityinLima,Peru.Afterextensive
testsonanimalsandthenonnormalhumans,Dr.Ramirez
reported"injecting50%or80%DMSOintramuscularlyinto
patientswithacuteandchronicschizophrenia"andthat"ofthe
14acutecases,everysingleonewasdischargedfromthe
hospitalwithin45daysafterthestartofDMSOtreatment...He
saidthat4ofthe11chroniccases,oneofwhomhasbeenillfor
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14years,weredischargedeventually,andtheother7improved
agreatdealandweregivenoccupationaltherapy...Heobserved
rapiddecreaseinagitation...recessionofpersecutionfeeling,a
relativelysuddentendencytocommunicateandtostayclean..,
thewaneofobsessions,returntoalertness,andacalmness
wheretherehadbeenrestlessnessandanxiety".Theonlyside
effectswerethecharacteristicgarliclikeodorofDMSO.
Attheendofthesymposium,afteranalmostdazzling
presentationofpapers,McGradyreportedthat"anFDAagent
turnedtoAnnSullivanofthePortlandOregonianandsaid
'DMSOisthrough'.Annlookedatthemaninamazementand
asked'Wheredidyouevergetthatidea?''Mybosstoldme',
theagentanswered."
Meanwhile,thedrugcompanieswhohadbeendoingclinical
trialswerereexaminingpatientsandgatheringdataregarding
possibleeyedamage.Squibbcollected3,000cases,Merck
17,000cases,andSyntex7,000.Noeyechangesordamageor
anyothersignoftoxicitywerefound.Bythistime,DMSOhad
beenusedin100,000people,andtherehadbeenno
complaintsofeyeproblemsanywhere.Additionally,sufficient
animaltestshadbeencarriedouttomakeitclearthatthelens
changesthathadbeenobservedwere"speciesspecific",i.e.,
theyonlyoccurredindogs,rabbits,andpigs,andnotin
monkeys,otherprimates,oranyotheranimals.
Neitherthepharmaceuticalreportsorthenewanimaltests
seemedtohavemucheffectontheFDA'snewcommissioner,
Dr.JamesGoddard.Goddardsoonshowedthatheintendedto
usethepolicepowersthatCongresshadgivenhimto
investigatescientists,whohadneverbeforebeentreatedthat
waybyfederalregulators.Quicklyadoptingatoughline,he
tooktheFDAintosomesurprisingnewareas.Speakingtoan
AMAconvention,heannouncedthat"theFDAisnowathird
partytothepracticeofmedicine",tothegeneralconsternation
ofthedoctors.ItbegantolookasthoughDr.Goddardwasout
toprovehetoocouldstopathalidomideandthathesuspected
maybeDMSOwasit.
DMSOpatients,however,didnotagree.Thosewhohadfound
DMSOaveritableWD40forarthritiswerefuriouswhentheir
painreturnedaftertheFDAstoppedDMSO.Theytalkedtothe
press,theycalledtheirsenatorsandcongressmen,andwrote
angryletterstotheFDA.PatMcGradyprovidesafewsamples:
Mybrotherhasarthritisofthespine.Heisinpainand
bedriddenmorethanhalfthetime.Whenheistreatedwith
DMSO,heisabletoleadanormal,activelife...JustONE
applicationofthischeap,safeDMSOchangedmybrotherfrom
agrimacingpatientintoanactive,painfreemaninexactly30
minutes!Multiplyhimandmyfamilybythousandsoftimes,
thenthinkwhattheFDA'sDivineRightofKingsLawisdoingto
thousandsandthousandsofpatientsandtheirfamilies.
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Ihadarthritisforfouryears,graduallygettingworseuntilIwas
insuchagonydayandnight.Iwasalmostatmywit'sends...I
heardofDrJacobandwenttovisithim...Almostfromthefirst
Ibegantogetrelief.NowIamonmyfeet,wellandactive...I
haveneverinmylifewishedillofanyonebutexperiencingthe
caliberofthisagency(FDA)Iwisheverylastoneofthemwould
suddenlyhaveanattackofacutearthritissopainfulthatyou
couldhearthemyellfromtheretohereandhavetobegforthe
onlydrugdiscoveredthatcouldgivethemrealhelp.
FDAstatementscontinuedtorefertoDMSO'sdangerousside
effectsbutgavenospecifics,nowho,when,where.Pat
McGradypressedfourconsecutiveFDAcommissionersfordata
onthe"dangerouseffects".Theyallrepliedthattheinformation
wasintheirfiles.Heaskedthemtoproduceitfourtimes.
Theypromisedtosendittohimfourtimes,butitnever
came.WhileOfficialMedicinehadstoppedDMSOresearchin
theU.S.,atleastitcouldgoonfreelyelsewhere.AThird
InternationalSymposiumonDMSOwasheldinViennain
November1966and250scientistsfrom12countriesattended.
Dr.ChaunceyLeake,askeynoter,said,"Fortunately,members
ofthehealthprofessionsthroughouttheworldarenotallbound
bythebureaucraticregulationsandjudgmentsoftheU.S.Food
andDrugAdministration".PatMcGrady,whoalsoattended,
commented"Itwasstrangehearingthisstatesmanofsciencein
thishallandthiscity,whichlessthanagenerationagohad
beenoccupiedbyoneofthebloodiestregimesinhistory,now
apologizeforregimentationinAmerica".
Healsoreported,"AsattheBerlinandNewYorksymposia,
scientistssaidtheyhadfailedtoinduceeyedamagewithDMSO
inanyanimalspeciesclosetothehuman,andtheycouldfind
noevidenceofeyetroublesattributabletoDMSOinany
patient".
Someoftheinterestingpaperspresented,McGradywrote,
showedthatDMSObenefited77%ofpatientswithrheumatoid
arthritisand84%withosteoarthritis,controlledmanykindsof
pain,spedhealing,offsetinjuriouseffectsofradiationtherapy,
andprovedsuperiortoallothertherapyforwinterandsports
injuries.Experimentsinanimalsshowedthatwhengivento
micetendaysbeforeinfection,DMSOpreventedtyphus,and
thatDMSOtendedtostabilizecollagen,apossibleantiaging
effect.McGradynotedthat"scoresofscientistsconfirmedthe
majorityofclaimsJacobhadmade...Distinguishedscientists
clusteredaroundhimandcongratulatedhimforwhatsome
calledaclassicalcontributiontoscienceandmedicine".Itwas
learnedattheconferencethatGermanyquietlywasrestoring
DMSOtodrugstoresasaprescriptionmedicine.
Dr.RichardBrobyn,whileaconsultantforMerck,haddeviseda
planforhumantoxicityexperimentsinprisoners.AftertheFDA
crackdown,MercklostinterestbutSquibblikedhisidea.Squibb
proposedtotheFDAthatSquibbandFDAsplitthecostfor
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Brobyn'splanandtheFDAagreed.Arrangementsweremade
forDr.Brobyntocarryoutthetrialsatthestateprisonin
VacavilleCaliforniainthefallof1967.
Bythistime,allresearchwithprisonerswascarriedoutin
accordancewiththeethicalprinciplesworkedoutbyDr.Andrew
IvywhenhewastheAmericanmedicalethicsadviseratthe
Nurembergtrials.Yearslater,Dr.BrobyntoldPatMcGradythat
hehimselftooktheamountofDMSOtobegiventothe
prisoners"becauseIwouldn'texpectapatientorexperimental
subjecttodosomethingIwouldn'tdomyself".
Brobyn'splanwasfor67maleprisonerstocoverthemselves
withtentimesthepermissiblehumandoseofDMSOeveryday
fortwoweeks,afterwhichtheywerecloselyexamined.Finding
notraceofanyeffectsotherthanarash(anoccasionalresultof
DMSOappliedtotheskin),thesecond,90dayphaseofthe
teststarted.Fortyprisonerssimilarlydousedthemselveseach
daywithDMSO,whichquicklypenetratedtheskin.Regularly
puttonumerousexamswithspecialattentiontoeyes,atthe
endof90daysnoevidenceoftoxicityhadbeenseeninthe
prisonersandtheattendingophthalmologistsawnoeffectatall
ontheprisoners'eyes.Dr.MortonWalkerobservedinDMSO,
Nature'sHealerthat"ifsugar,salt,coffee,orteahadbeen
takenbytheprisonersoverthreemonthsinquantitiesequalto
theDMSOtheyabsorbed,itwouldhavekilledthem".Pat
McGradylateraskedDr.Brobynwhatifhehadgiventhe
prisonerstentimesthepermissibledoseofaspirineverdayfor
threemonths.Brobynreplied,"You'reasking...isaspirinmore
toxicthanDMSO?Myanswer:Certainly".
Brobynwasright.Theclassictestfortoxicityisknownasthe
LD50test,whichmeasuresthelethaldose(LD)atwhichhalf
ofagroupoftestanimalsiskilled.TheLD50testsforaspirin
andDMSOshowthataspirinisseventimesastoxicasDMSO.
AyearaftertheVacavilletests,theFDAlifteditsbanonclinical
testinginhumansandapprovedtestsofDMSOinrheumatoid
arthritisandsclerodermaand,separately,insprains,bursitis,
andtendinitis.Thisdidnotreleaseittodoctorsforgeneraluse
intheseconditions,butonlypermitteddrugcompaniesto
preparecomplicatedapplicationsfortestinginthem.
In1970,Dr.M.BrandsmaofLosAngelesreportedthatacase
ofsystemiclupuserythematosus,whichhadnotrespondedto
prednisone,hadgoneintoremissionforthreeyears(atthetime
ofreporting)fromDMSO.Thesameyear,Britishscientists
foundintwodoubleblindstudiesthatDMSOcombinedwith
idoxyuridinestoppedthesufferingfrompainfulshinglesinfrom
2to9days.
VariouspiecesofresearchhadshownDMSOtobeeffective
againstvirusesandanimportantclueastowhythishappened
wasgivenin1971byDr.M.KunzeandassociatesinVienna.
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Theirstudycheckedtheproductionofinterferoninmice
followinginfectionofthemicebythescientistswithcertain
viruses.TheyreportedthatwhenDMSOwasinjected10
minutesafterthemicewereinfectedwithviruses,"theanimals
producedanywherefrom2to16timesasmuchinterferonas
theywouldhave,hadnoDMSObeengivenaftertheirbeing
infected".
TheverysignificantfactthatDMSOwouldcrossthebloodbrain
barrierhadbeenevidentfromDr.Jacob'searlyresearch.For
thoseinterestedin"smartpills",theearly1970'sworkwhich
JohnL.BrinkandDonaldG.SteinofClarkUniversitypublished
inVolume158ofSciencemagazineisrelevant.Magnesium
pemoline(PMH)hadalreadybeennotedtoimprovelearningin
ratsandinhumans.BrinkandSteinreportedthatPMH
dissolvedin100%DMSOgreatlyincreasedrats'learning
abilitiesoverwhatwasachievedwithpemolinealone.Injecting
intoratsasolutionofradioactivePMHorasolutionof
radioactivePMHdissolvedinDMSO,theynotedthatthe
DMSO/PMHsolutionwasfrom50%100%moresuccessfulin
crossingthebloodbrainbarrierthanthePMH+watersolution
alone.
PatMcGradyonceaskedDr.StanleyJacobwhowouldgainthe
mostfromDMSO.HereisDr.Jacob'sanswer."Quadraplegiais
thesaddestthingthathappenstopeople.Itoccursmostoften
totheyoungandhealthy,tosoldiersfightingourwars,to
youngstersdriving,toathletesinpersonalcontactgames.Asa
quadraplegic,youlieinbed,atotalvegetable.Yourmind
functionsbutyoucannotpassurineorhaveabowelmovement
withouthelp...Somanyofthemeventuallysaytome'Dr.
Jacob,Icouldn'tevencommitsuicide'."JacobtoldMcGrady
aboutonesuchpatient,acasewherehewascalledinalmost
immediatelyfollowinganaccident."A16yearoldgirl,afine
athlete,whodoveoffaboardandlandedonherneckonthe
bottomofthepool.Herdoctorwaspessimisticbutwillingtotry
almostanythingthatofferedaglimmerofhope.Shewasa
completequadraplegic,utterlyhelpless.ShewasonDMSOfor
anentireyear.Graduallyonebyone,itseemedherorgans
begantofunctionagain.Eventually,shewalked.Andnowsheis
incollege,doingverywell."
ThiswasaccomplishedwiththemedicineonwhichFDAbanned
researchintheU.S.in1965.Itwas13yearslaterbeforethe
FDAapprovedDMSOasaprescriptiondrugforusein
interstitialcystitis.
GreyKeinsleyofLittleton,Colorado,istheonetime
quadraplegicmentionedearlierbyDr.Jacob,whowentonto
collegeandtoajobinabank.ButKeinsleydidnotstartDMSO
untilFebruary1965,twoyearsafterhisaccident.ByAugust
1965,heliftedbotharmsoverhisheadandputonaTshirt
unassisted.Alittlelatersensationbegantoreturntohislower
chestandhisrighthip.ThentheFDAbannedDMSO,andhe
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wasdeprivedofitforthreeyears,startingagainonlyin1968.
Thenextyear,hereceivedhisbachelorofartsdegreein
economics.HismothertoldMcGradythatDr.Jacobnotonlydid
notchargeforhisservices,butpaidbillsforextensivemedical
examinationswhichweredoneinColorado.McGradyreported
thatasof1973,GreyKeinsleycouldmovebothofhislegs.
GreyKeinsleyistheonlyknowncaseofaquadraplegic
regainingmovementofthelowerlimbswhentherapywas
startedtwoyearsaftertheaccident.Dr.Jacobhasseentwo
quadraplegicpatientsrecovercompletelywhenDMSOwas
startedwithinonehouraftertheaccident.
In1971,SquibbPharmaceuticalagainfiledanNDA,stating
oncemorethatDMSOwasreadytobecomeaprescriptiondrug,
andagainwasturneddownbytheFDA.
In1972,thepredictionin1964ofStanleyJacob'scolleague
cametruetheFDAaskedtheNationalAcademyofSciences
(NAS),throughitsNationalResearchCounciltomakean
"independentreview"ofallinformationontheeffectivenessand
toxicityofDMSO.However,theNASgotmuchofitsfundingat
thattimefromtheFDA.AnNASofficertoldPatMcGrady"we
havebeenaskedtowashtheFDA'sdirtylinen,andwehave
agreed."
McGradylearnedthattheNASintendedtotake4monthsjust
toplanhowitwouldreadthe1,200papers(atthattime)on
DMSO,andthentotake1824monthstodoso.Atapress
conference,McGradytoldtheNASpresidentthat,havingread
allthepapers,hecalculatedthathe,asaslowreader,could
readthemallinthreeweeks,orafastreadercouldgothrough
themallintwoweeks.
Insteadoftakingtwoyearstoreadthematerial,McGrady
challenged,whynotsetthreefastreaderstogooverthepapers
intwoweeksandthenfreethedrugformedicaluseifno
reasonwasfoundtocontinuetheban.Thiswouldbepreferable,
hepointedout,toholdingupresearchonDMSO,sincethe
publishedstudiesseemedtoshownotoxicitytohumans.He
furthersuggestedthattheFDAberequiredtoprovidesolid
evidenceoftoxicity,iftheyhadany,whileDr.Jacobandhis
colleaguesbeinvitedtoprovideallfavorableandunfavorable
reports.
Thesesuggestionswereapparentlyfartoosensibletobetaken
seriously.Whenthereportcameoutin1974,itseemedas
thoughtheOfficialMedicineoftheFDAwasspeakingthrough
themouthoftheNAS.Thereportstated(despite1,200papers
tothecontrary)that"therewasinadequatescientificevidence
ofeffectivenessofDMSOforthetreatmentofanydisease,and
thatthetoxicitypotentialwassufficientlygreatthatthedrug
shouldremainaninvestigationaldrug".ThusDMSOwouldnot
bereleasedfordoctorstouseingeneralpractice,butwould
remainbottledup.
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In1974,anothersymposiumonDMSOwasheldattheNew
YorkAcademyofSciences.In1975,theuniversallylikedPat
McGrady,oncescienceadvisortotheAmericanCancerSociety,
diedofcancer.HisDMSO,thePersecutedDrugisaclassicon
theearlyyearsofDMSO.
Meanwhile,inHouston,Dr.EliJordonTucker,anelderlyand
highlyrespectedorthopedicsurgeon,wastreatingcancerwitha
combinationofDMSOandhematoxylon,anontoxicdye
sometimesusedasamedicine.Inexperimentsincancerous
miceconductedbyThomasD.Rogers,PhD,underthe
supervisionofVernonScholesMDatNorthTexasState
University,themixturewasseentogodirectlytotumorsand
nowhereelse,whereiteffectivelystarvedthem.Hematoxylon
withoutDMSOwasfoundtohavenoeffectatalloncancer.In
1972,HoustonKHOUTVnewsmanRonStonedida
documentaryonDr.Tucker'sachievementsincancer.Dr.
TuckerhimselfneverpublishedhisDMSOhematoxylonresults
after1968outofconcernoverlosinghislicenseforusingan
unapproveddrug.Dr.MortonWalkerdevoted30pagesofhis
DMSO,Nature'sHealertothefascinatingstoryofDr.Tucker.
(WithDr.JohnSessions,Dr.WalkerhasalsowrittenCoping
withCancer,afurtherdiscussionofDMSOtherapyforcancer
bothbooksareavailablefromFreelanceCommunications,484
HighRidgeRoad,Stamford,CT069043095.)
FindinghisDMSOhematoxylonmixeffectiveinlargecell
lymphosarcomaandadenocarcinomaindogs,Dr.Tuckerworked
outahumandosagewhichhegaveonlytoterminalpatients.
OnewhorememberstheDMSOcombinationandDr.Tucker
verywellisAlvaRuthWilsonintheHoustonarea.Shequalified
forhistreatmentbecausewhenshesoughthimout(after
hearingtheTVprogram),shehadbeengivensixmonthstolive
fromlymphosarcoma.StartinginJanuary1973,shetookan
intravenousdripoftheDMSOhematoxylonmixturefivedaysa
week.BeforerequestingDr.Tucker'streatment,Mrs.Wilson
hadmaximumamountsofchemotherapyandradiation,but
neitherhelpedthetumorskeptonspreading.Chemotherapy
hadtobestoppedbecauseitssideeffectsweregivingher
leukopenia,adiseaseinwhichherwhitecellshaddroppedto
waybelownormal,leavingherwithalmostnoimmunity.While
shewasonDr.Tucker'sprogram,herconventionaldoctor
wantedtogivehermoreradiation.Dr.Tuckertoldherthat
sinceshewasonDMSO,theradiationwouldnothurther,afact
wellestablishedbyclinicalstudiesinvariouscountriesand
virtuallyignoredintheUnitedStates.Althoughnoprimary
sourceofhercancerwaseverfound,somecloudinessinXrays
ofthestomacharousedsuspicion,sothatwaswherethe
radiationwasdirected.Anotherwoman(notoneofDr.Tucker's
patients)whostartedradiationofthestomachthesameday
returnedforthesecondtreatmentinawheelchair,soillhadthe
radiationmadeher,andforthethirdonastretcherasapatient
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inthehospital.ButMrs.Wilson,takingherdailyDMSOI.V.,
tookthesameradiationandfeltgreat.ByJanuary1974,aftera
yearonDr.Tucker'sprogram,nomoretumorscouldbefound
andshecontinuesinfinehealthin2000.
AsfarasDr.Jacobknows,DMSOwasnotusedonthosewho
sufferedradiationdamageatChernobyl.
AnotherofDr.Tucker'ssuccessstories,JoeFloydofSpring,
Texas,was71andingoodhealthwheninterviewedbyDr.
Walkerin1989.In1974,Floydwasstrickenwithdeadly
adenocarcinoma.Bycoincidence,hisdoctor'swifehadthesame
kindofcancerandthedoctorurgedFloydtotakethe
chemotherapyhiswifewouldtake.Floyddemurredandsought
outDr.Tucker.
Sixmonthslater,hewasbackatwork,butthedoctor'swife
wasdead.
ClydeRobertLindsayknowsaboutDMSO.At3yearsofage,in
1966,hewasgivenupfordeadwithcancer.Dr.Tuckergave
hismotheradropperbottleofDMSO+hematoxylonandtoldher
togivehim5dropsindistilledwatereverymorningonan
emptystomach.In1992,Dr.Walkerfoundhimtobeabig,
strongyoungmanof29.
WhileresearchingforDMSO,Nature'sHealer,Dr.Walkervisited
Dr.Tucker,whogavehimhisformula.Then,asWalker
explains,"Dr.Tuckerhimselfcamedownwithaformofcancer
thatwouldhaverespondedtohisDMSO+hematoxylon
treatment,butbeforehecouldadministerittohimself,hefell
intoacoma".Noonehadaccesstotheformula,andDr.Walker
didnotknowthatDr.TuckerneededituntilafterDr.Tucker
died.
TomakesureDr.Tucker'sformuladoesnotgetlost,Dr.Walker
printeditinDMSO,Nature'sHealer,withcomp1eteinstructions
forpreparationanddosage.Walkernotesthatthetreatment
solutioncanbetakenorally(thewayClydeRobertLindsaytook
it).
Dr.Tucker'sremarkablework,asyetunnoticedbyconventional
medicine,shouldnotbeconsideredsurprisingsincetherehave
beennumerousstudiesindicatingthatDMSOeitherbyitselfor
incombinationwithotherdrugscanbehelpfulincancer.As
mentionedearlier,DMSOisknowntostimulatethebody's
productionofinterferonwhich,synthesized,hasbeenusedin
cancertreatment.DMSOhasbeenfoundtopotentiatecertain
chemotherapieswhilerenderingthemlesstoxic,andthishas
beenreportedinthemedicalliterature.DMSOwouldpermit
saferandmoreeffectiveuseofradiationincancertreatment,
becauseofitsprotectiveaction(asnotedinMrs.Wilson'scase).
Thiswasoriginallyreportedin1961.TheMarch1985Russian
radiologicaljournalMeditsinkayaRadiologiareportedontheuse
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ofDMSOwithradiationincancertreatment.
PatMcGradynotedthatthelateDr.FlorenceSeibert,oneofthe
researchersinpleomorphicorganisms,observedthat
"organismsfrequentlyfoundincancerandleukemiapatients
suspectedasacauseforcancer(thesortthatRoyalRifeandDr.
GrunerofMontrealsaw)stoppedgrowingwhenexposedto25%
DMSO...Dr.RobertSchrekandassociatesoftheVeterans
HospitalinHines,Illinois,foundthattwopercentDMSO,which
hadnoeffectonnormalcellsaftertwodays,killed90%ofthe
leukemiccellsinasingleday...NotedvirologistDr.Charlotte
FriendofNewYork'sMountSinaiSchoolofMedicine
transformedleukemiccellsbacktonormal,hemoglobin
manufacturingcellswithaveryweakconcentrationof(2%)
DMSOaddedtothemediuminwhichcellsweregrowing...In
April1973,Drs.EtienneandJennieLasfarguesoftheInstitute
ofMedicalResearchinCamden,NJ,reportedthatwhileDMSO
increasedthenumberofvirusinfectedmousebreastcancer
cellssixfoldforawhile,bytheendofthreemonths,DMS0had
completelyridtheculturesofinfectedcancercells".
McGradyalsonotedthat"Dr.LeoStjernvall,aUniversityof
Helsinkipathologist,andhisassociateDr.K.Setala...reported
thatcancercells..,buildaprotective'cytoplasmicbarrier'which
preventsthepoisonsof(variouscancerdrugs)fromseeping
insidethecellsandkillingthemorarrestingtheirgrowth.
Stjernvalldissolvedtheanticancerdrugvinblastinesulfatein
DMSOanddabbeditoncancerthathehadinducedwith
chemicalsappliedtoamouse'sskin.Thefibrouscytoplasmic
barriersmeltedawayandotherstructureschangedsothatthe
cancercellstookontheappearanceofbenignlyovergrownbut
otherwisenormalcells.Othercommonanticancerdrugs
becameequallyeffectivewhendissolvedinDMSO.The
experimentsshowedthatDMSOtransporteddrugscanalterthe
malignantcelltowardnormal."Thefibrousbarrierreferredto
byDr.StjernvallisthefibrincoverdescribedintheHoxsey
chapter.Whateverwilldissolvethatcoveropensupacancer
tumortoattackbythebody'simmunesystemifitishealthy
orbycancercellkilling(cytotoxic)drugssomuchincurrent
use.
HowdidtheNationalCancerInstitute's"WaronCancer"
overlooktheextensiveresearchonDMSOandcancer?
Heartattack,cancerandstrokethethreegreatestkillersin
theU.S.andDMSOhasrelevancetothemall,buthowmany
peopleknowthis?
TheFDA,atleast,knewaboutDr.Tucker.InvitedtoNewYork
in1978bydoctorswantingtolearnabouthiscancertreatment,
heaskedJoeFloydtogoalong.Whileplanningthetrip,Tucker
receivedacallfromDr.K.C.Pani,theFDAofficialinchargeof
DMSOsince1968.PanihadheardofTucker'sworkandinvited
himtostopinWashingtonenroutetoNewYork.Tuckervisited
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Pani,showinghimvariouspatientrecords,Xrays,andslides.
Dr.MortonWalkertellsthestory,"WhentheycametoFloyd's
record,Dr.Paniasked'Howlongdidthisonelast?'Tucker
replied'He'ssittingdowninthelobby'.Panisaid'Iwantto
meetthisdeadman'.TheysoughtoutMr.Floyd,whotoldhis
story.ThentheFDAofficial,visiblyimpressed,saidhewouldbe
intouchwithTuckersoon.Healsomentionedthathewasin
contactwithDr.StanleyJacobofOregonandthathewas
monitoringtheuseofDM50."
Aboutoneweeklater,theFDAapprovedtheuseofDMSOin
thetreatmentofinterstitialcystitis.This1978actionwasthe
firsttimeFDAhadapprovedDMSOasaprescriptiondrugfor
anyhumanailment.Consideringthatithadbeen13yearssince
thecrackdown,itwasamajorbreakthrough,anditcertainly
seemedthatDr.Tuckerhadhadsomethingtodowith
precipitatingit.
Unbelievably,asweenterthe21Stcenturyalltheseyearslater,
itisstilltheonlyFDAapprovedhumanuseforDMSO.Itisalso
approvedforthepreservationoffrozenhumantissues,thefirst
usetowhichStanleyJacobputDMSO.Ironictothinkthat
surgeonssoakinDMSOtissuessuchasthebonemarrowwhich
theywilllaterplaceinhumanbodies.Thischemicalisfamous
foritspenetratingabilities,sosuchtransplantsareobviously
drenchedinDMSO.It'sconsideredsafeenoughtobeapproved
forthat,butnotforgeneralmedicaluse,fordoctorstousein
anyofthehundredsofwayswhereDMSOcanbeeffective.
WhatdoestheFDAthinkitissavingusfrom?
TheFDAusedthebogusissueofeyedamageforseveral
decadestoholdbackDMSO.Dr.Walkerpointsoutthat
"adverseeyefindingshavebeenreportedwithallthearthritis
drugs,suchasAnaprox,Naprosyn,andMotrin(aspertheir
packageinserts)yetnoonehassuggestedthattheseminimally
effectivedrugsbetakenoffthemarket."
Asfaraseyesareconcerned,theevidenceonDMSOisquiteto
thecontrary.WhenseveralpatientstreatedwithDMSOfor
muscularproblemsreportedtoDr.Jacobthattheirvisionhad
improved,hesentthemtoDr.RobertO.Hill,ophthalmologist
attheUniversityofOregonMedicalSchool.Confirmingthe
favorablechanges,Dr.Hillbeganhisownexperimentswith
DMSO(afteritwasknownthatthelenschangesdidnothappen
inhumans).Hisresearchshoweddropsof50%DMSOtobe
effectiveinretinitispigmentosaandmaculardegeneration,and
presentedareportonthisattheNewYorkAcademyofSciences
symposiumin1971.
Inthe1970's,mylatemotherdevelopedmaculardegeneration.
HavingreadDr.Hill'sstudy,Icalledhim.Inadditiontowhat
hehadwritten,headdedthatoneshouldusecoldcompresses
afterusingthedrops.Irelayedthistomymotherandwhen
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shewasathomeonesummer,herhousekeeperputtwodrops
of50%DMSOineacheyetwiceaday.Whenmymotherwas
gettingreadytoreturntoFloridaforthewinter,shesaid,
"ThoseDMSOdropsworked.WhenIcamehomeinJune,lying
inbedIcouldnotseetheindividualslatsonthevenetianblinds
inmybedroomandnowIcan".
Deise,afriendfromBrazil(whereDMSOislegal),toldmethat
aNewYorkeyedoctorhadtoldhershewasdevelopingmacular
degeneration,soItoldhertheabovestory.Ayearlater,she
informedmethatthesamedoctorhadtoldherthathersigns
ofmaculardegenerationhaddisappeared.Thepreviousyear,
shehadpersistentlyputDMSOdropsinhereyesseveraltimes
aday.
TellinganotherfriendwithmaculardegenerationofDeise's
experience,shelookedforDMSOatahealthfoodstoreand
thenbalked.ThebottleofDMSO,shepointedout,wasclearly
labeled"Donotgetintotheeyes.Donottouchtheskin.Ifgets
onskin,callaphysician".Thelabelalsoread"Thisissoldonly
asasolvent".Callingthe800numberonthelabel,Ilearned
thattheproductwaspureDMSO,notindustrialgrade.With
thatsortofwarningonthelabel,howcouldanyoneguessthat
theliquidinthatbottleisusedontheskinofmanyathletic
teamswhentherearemuscularinjuries.Suchistheresultof
FDA'spolicyofcensoringtruthfulhealthclaims,preventing
Americansfromlearningwhatthisandotherproductscando
forthem.
In1978,Dr.ArthurScherbel,thenchiefofRheumatologyat
theClevelandClinic,carriedoutastudyoftheuseofDMSO
intravenouslyinscleroderma,aparticularlymiserabledisease
affectingaround150,000Americans.Partsofthebody
increasinglycalcifyandbecomerigid,aneventuallyfatal
conditionforwhichtherewasthenandstillisnocure.Dr.
ScherbelfoundclearevidenceofDMSO'sefficacyinscleroderma
andsubmittedhistrialwithaNewDrugApplication(NDA)to
theFDA,whichturnedhimdown.DMSOisapprovedforusein
sclerodermainCanada.
Somethingelsehappenedin1978thatopenedwindowsinthe
overregulatedU.S.medicalsystem.ThechemicalEDTAhas
longbeenonthe"GRAS"list(GenerallyRegardedAsSafe)and
isFDAapprovedforuseintravenouslyfortheremovaloflead,
incasesofleadpoisoning.ReasoningthatifEDTAcouldremove
leaditmightalsoremovecalcium,certainmedicalpioneers
triedEDTAtodealwithcalcifiedarteries,andsawpatients'
circulationimprove.ThelateDr.RayEverswasoneofthe
foremostofthosepioneers.SoontheFDAcamedownonhim
forhis"unapproved"useofEDTA.Insteadofcavingin,Dr.
EverssuedtheFDAinFederalCourt,askingforaninjunctionto
stoptheagencyfrominterferinginhispracticeofmedicine.
Thiswasnottheirbusiness,hedeclared,butrathermaking
surethatdrugsaresafe.SinceFDAhadlongsincedeclared
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thatEDTAwassafeforuseinhumans,hetoldthecourtthatas
alicensedphysicianitwashisrighttouseasafedrugin
whateverwayhefoundtobeuseful.TheFDA'sinterpretationof
currentlawwasthenandstillisthatitrequiresthemtocontrol
everyusageofeverydrug.Totheirchagrin,theCourtagreed
withDr.Evers,stating,"CongressdidnotempowertheFDAto
interferewithmedicalpracticebylimitingtheabilityof
physicianstoprescribeaccordingtotheirbestjudgment".The
FDAappealed,andhewonagain.TheFDAdidnotappeala
secondtime,lettingtherulingstand.
TheEversRulingthusmakesitlegalforadoctortouseanFDA
approveddruginanywayhe/shethinksfit.Combinedwiththe
FDA's1978approvalforuseininterstitialcystitis,thismeant
thatsinceDMSOhadbeenapprovedforonehumanuse,
doctorscouldnowuseitforotherhumanuses,andmanydid.
In1979,justtomakesuretheFDAdidn'tinterfere,theOregon
legislaturepassedabillprotectingDr.Jacob'srighttouse
DMSOwithinthestate.
InSeptember1979,theFDApublishedaregulationabolishing
its1965regulationwhichhadbannedgeneralresearchin
DMSO,butitsposturewasstillsuspicious.Theunbending
bureaucracywasbeginningtobendabit,butitwasalittlelate.
FDAhadsaidnosomanytimesthatdrugcompanieswere
beginningtobelievetheymeantitandmedicalstudiesbegan
toslowdown.ItwastakingthepatienceofJobtopersistwith
DMSOagainstsuchopposition,arepeatofthepatternwithDr.
Ivy.TheFDAhadputoutsomuchstaticthatthescientific
communitybegantobackoff.
Still,theEversRulinghadopenedthingsupconsiderably,and
certainbolddoctorsproceededtouseDMSOintravenously,
oftenseeingdramaticresults.OneofthosepioneerswasDr.
WilliamCampbellDouglass,apersonusedtomakinghisown
decisions.Mrs.RuthLewisofSarasota,Florida,toldDr.Morton
WalkerofherexperienceswithDr.Douglass.Rheumatoid
arthritiscausedhersomuchpainshecouldnotwalkwithouta
cane.Afterabackinjury,shewastoldshehadtoremaininbed
forsixmonths.Realizingthatifshedidsoshemightneverwalk
again,evenwithcanes,shedecidedtotrysomethingelse.Her
sonandhusbandliterallycarriedherintoDr.Douglass'office,
theninMarietta,Georgia,"unabletoputbothfeetonthe
ground",shetoldDr.Walker."After21/2weeksofDMSO
treatment,Iwalkedoutofthatofficewithoutanyhelp
whatsoeveroracane.Ihadbeenunabletoclosemyrighthand
completelyforoverayear.Itkeptmeawakeatnightwithpain.
ButaftertheI.V.,topical,andoraltreatments,Icannowclose
myhandtightly.Thearthritishasnotreturned."
InDMSO,Nature'sHealer,Dr.WalkerexplainsDMSO'sactionin
arthritis,"DM50isascavengerofhydroxyradicals,andthis
chemicalIONisdominantinarthritis.Hydroxyradicalsare
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responsibleforbreakingdownthesynovialfluidandthe
cartilageofthejoints.[DMSOis]oneofthefewknown
substancesresponsiblefordetoxifyingthisradical...Neutralizing
thishighlytoxicfreeradicalcausesthereductionof
inflammationandthediminishingofpaininarthritis.Itis
probablytheprimarymechanismthatallowsDMSOtowork
effectivelyagainstarthritis".
Dr.DouglasstoldDr.Walkerofanotherstartlingcase.Penelope
PappasofSarasota,Florida,thensixyearsold,putherindex
fingerintoalivelightsocket.Beforeshecouldwithdrewit,it
was"cookedthroughandburnedashwhiteatthetip".Within
30minutes,Dr.Douglasswasabletohavethefingersoakingin
fullstrengthDMSOasthechildscreamedwithpain.Bytheend
of20minutesimmersionintheliquid,thechildhadstopped
cryingbecauseshefeltnomorediscomfort.Sheslept
undisturbedallnightandthenextdayshowedapinkand
healingindexfinger.Atthetime...itwasfeltthatshewould
probablylosethetipofherfingerfromgangrene.Thefinger
healedcompletely.
In1980,MikeWallacefeaturedDMSOontwoprograms,firston
March23.andthenonJuly6.Dr.RichardCroutoftheFDA
appearedontheMarchshow,insistingthattherecouldbeno
FDAapprovalofDMSOwithoutdoubleblindstudies.Heknew
aswellasanybodythatthisisvirtuallyimpossiblewithDMSO
becauseofitssmellanyo
Logged
Hehidethmysoulinthecleftoftherock,Thatshadowsadry,thirstylandHehidethmylife
inthedepthsofHislove,AndcoversmetherewithHishand.
Niall Re:DMSO
SuperModerator Dimethylsulphoxide
Reply#163on:August17,2010,
12:29:12PM
Quote
OnMarch23andJuly6,1980,MikeWallacehadtwo60
MinutesprogramsonDMSO.
Posts:3,102
I'vefoundthe60MinutesvideoonDMSO:
Part1
Part2
Part3
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1/3/2016 DMSODimethylsulphoxide
IlovehowSandysparksupaMore'sciginpart3
Logged
"Inrightknowledgethestudyofmanmustproceedonparallellineswiththestudyofthe
world,andthestudyoftheworldmustrunparallelwiththestudyofman."
G.I.Gurdjieff
Niall Re:DMSO
SuperModerator Dimethylsulphoxide
Reply#164on:August17,2010,
07:46:28PM
Ifoundthishere:
_http://www.healthsalon.org/319/dmsoandcancer/
Posts:3,102 ThissitealsopromotesMMS,asIdiscoveredwhenIwastoldina
scathingemailthatmycommentlinkingtoSOTTarticlesonMMS
andHumblewouldbedeletedandthatIshouldneverpostthere
again!
Quote
ThefollowingisanexcerptfromDrMortonWalker'sbook,
DMSO:NaturesHealer
Background
DMSOdimethylsulfoxideisasimplebyproductofthewood
industryandisasolventthatcanbeproducedinindustrialor
pharmaceuticalgrade.DMSOhasvariouslybeencalleda
miraclecompoundcapableofrelievingpain,diminishing
swelling,reducinginflammation,encouraginghealingand
restoringnormalcellfunction.Oneofthemostwellknownand
exoticpropertiesofthissolventisitsabilitytopenetrateliving
tissueandtransportothermedicinesintheirintegralstatedeep
intothebody.Forthisreason,DMSOhasbeenusedbymanyin
thetreatmentofburnsandsprains,sportsinjuries,paralysis,
arthritis,sclerodermaandmanyofthedegenerativediseases.
Americandoctor,StanleyWJacobhasworkedwithDMSOfor
manyyearsandisconsideredoneoftheforemostauthoritieson
thesubstanceintheworld.Hestatesthefollowingwithregard
tothetherapeuticpotentialofDMSO:Wevebarelyscratched
thesurface[ofDMSOscapabilities],forthisisanewprinciple
inmedicine.Weveonlyhadthreenewprinciplesinourcentury
theantibioticprinciple,thecortisoneprinciple,andnowthe
DMSOprincipleandtheDMSOprincipleistheonlyoneofour
generation.Despiteallthecontroversy,myguessisthathistory
willrecorditthisway.
WhenUSGovernorGeorgeWallacetravelledacrossthecountry
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tofindpainrelieffromDMSOadministeredbyDrJacob,the
reputationofthispainkillingsolventgotatremendousboost2.
Wallacehadbeenconfinedtoawheelchairsincehewas
woundedina1972assassinationattemptwhilecampaigningfor
theDemocraticnominationforPresidentatLaurel,Maryland.
Wallacesdiscomforturewaslocatedinhisflank,acondition
whichreportedlydisappearedbyfaithfullydabbingDMSOover
theaffectedarea.
DMSOGoesPublic
On23rdMarch1980andagainon6thJulyofthatyear,the
populartelevisionprogram60MinutesreportedonDMSO.Ina
presentationentitledTheRiddleofDMSO,presenterMike
Wallacecoveredtheanecdotalpatienthistoryofthesolventand
intervieweditsmaincriticsattheFDA.Asaresultofthe
broadcast,whichreachedthehomesof70millionviewers,the
switchboardsatDrJacobsofficeandothersassociatedwiththe
programwereimmediatelyswampedwithupto10,000people
figurativelycrying,Saveme!Savemefrommypain!Pain
victimssoughtoutotherphysiciansaroundtheUnitedStates
whowereknowntoprescribeDMSO.Theyarrivedindroves.
TelephonesintheofficesofdoctorsandpharmaciesinFlorida,
Oregon,LouisianaandNevadarangbusilyforseveraldays
followingtheSundayeveningbroadcastof60Minutes.A
subsequentwireservicereportabouttheFDAsrefusalto
approveDMSOappearedaroundthecountryinTuesdays
newspapers.Inhisprogramfootnote,presenterMikeWallace
stated,TomorrowmorninginWashington,theHouse
CommitteeonAgeingbeginsaninquiryintowhyDMSOisnot
availabletoallAmericansforanyappropriateailment,including
plainandsimplepain.Thenumbersoflettersandtelephone
callsthatcameintocongressionalofficesenquiringaboutthe
causeofDMSOunavailabilityweremassive.Asamplingofthe
letterssenttojustonecongressman,ClaudePepperofFlorida,
arefoundinchapter4ofmybook.
DMSOBaneoftheEstablishment
Dimethylsulfoxidehashadabatteredthirtyyearhistory
completelyoutofproportiontoitstruetrackrecord.Officially,
DMSOhasneverbeenapprovedforwidespreadmedicinaluse
becausemedicalauthoritiesdeclarethatthequalityofmedical
trialsandresearchonthesubstancehasnotbeenupto
statutoryrequirements.DrJRichardCrout,thechiefFDA
opponenttoDMSO,reportedthatdoubleblindtests3were
mandatorybeforeapprovalwouldbeforthcomingfromhis
agency.Yetresearcherscannotconductdoubleblindtestson
DMSObecauseofthedistinctiveodourproducedbytheproduct
afterapplication.Withinafewminutesofputtingitonyour
skin,youcantasteitonyourtongueitpenetratestheskinand
runsthroughthebloodstreamsoeffectively.Thealternative
reasonfornotapprovingdimethylsulfoxide,accordingtosome
DMSOproponents,couldalsobeasimplequestionof
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economics:DMSO,painkillerextraordinary,isacommonby
productofthewoodindustryandcannotbepatentedtogreat
profitbythepharmaceuticalindustry.Ironically,evendrug
companieshavehadtheirDMSOINDsturneddown4.
TheMedicalCommunityDivided
BecauseofthegeneralpublicoutcryaboutitsbanintheUnited
States,andofcoursebecauseofMikeWallaceandhis60
Minutes,DMSOhasbecomeahouseholdwordandmedical
politicalcauseclbre.Thosedoctorsamonguswhohavebeen
usingthedrugfortwentysixtotwentyeightyearsnever
dreamedthatitwouldbecomeafocalpointinthecontinuing
battlebetweenindividualfreedomandthepowerof
government.MycolleaguesandIhavebeencriticized,ridiculed
andevenpersecutedinsomemedicalcirclesforpromotingand
usingDMSO.ButI,andotherslikeme,havecometothe
conclusion,havingobservedestablishmentthinkingforforty
years,thattheonlywayatrulyrevolutionarytreatment
principlecanbebroughttothepatientisbyappealingtothe
generalpopulationthroughtheinformationmedia.Itisforthis
reasonthatIwrotethebook,DMSONaturesHealer.
Inspiteoftherumours,DMSOhasnotbeenfoundunsafefor
humans.Anysideeffectsaremerelyminorirritations.DMSO
stopsbacterialgrowth.Itrelievespain.Asavasodilator,the
drugenlargessmallbloodvessels,increasingthecirculationto
anarea.Itsoftensscartissueandsoothesburns.DMSOsanti
inflammatoryactivityrelievestheswellingandinflammationof
arthritis,bursitis,tendinitis,andothermusculoskeletalinjuries.
DMSOhasbeenfoundtobenefithumanbodycells,tissuesand
organsinwaysnotyetproperlyunderstoodbymedicalscience.
Forthisreason,IbelieveDMSOisthe21stcenturysnewest
healingprinciplewithaverywiderangeofusefulness.It
representsanentirelydifferentwayoftreatingdiseases.
DMSOandCancer
CancerseemstorespondwelltoDMSO.AtMountSinaiHospital
inNewYorkCity,CharlotteFriendMDhasturnedcancerous
cellsintoharmless,normalonesinthetesttubebyputting
themintouchwiththeDMSOsolutions.DMSOisroutinelyused
byalternativecancerclinicsinMexicototransportlaetrile
intravenouslyintothebody.Becauseofextremelypromising
clinicalresults,researchisstillongoingonaprivatelyfunded
basisintoDMSOspotentialroleinthebreakingupoftumours
andthekillingofmetastaticcancercellsinitsownright.Yet
theUnitedStatesFood&DrugAdministrationandtheUK
MedicinesControlAgencycontinuetoforbidtheadvertisingand
retailingofDMSOforanymedicinalpurposessaveone:forthe
treatmentoftherareurinarybladdercondition,interstitial
cystitis.
AsreportedintheJournalofClinicalOncologyinNovember
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1988,twentycancerpatientswithextravasationof
anthracycline(destructivesecretionsfromtissuesofthetoxic
chemotherapeuticagentanthracyclineontotherecipientsskin
withthepotentialtoformcancerousulcers)weretreatedona
singlearmpilotstudywithtopicallyapplied99%DMSOand
observedforthreemonthswithregularexaminationsand
photographs.DMSOwastopicallyappliedtoapproximately
twicethesurfaceareaaffectedbytheextravasationandallowed
toairdry.Thiswasrepeatedeverysixhoursforfourteendays.
Innopatientdidextravasationprogresstocancerousulceration
orrequiresurgicalintervention,asisusualwiththistoxic
chemotherapeuticagentforcancer.Theauthorsofthisreport
suggestthatulcerationwasstatisticallylikelytohaveoccurred
inatleast17%ofthesepatients.Theonlysideeffectsreported
fromDMSOusageincludedaburningfeelingonapplications,
subsequentlyassociatedwithitch,redness,andmildscaling.
Sixpatientsreportedacharacteristicbreathodourassociated
withoysters.TheoncologistsstatedthattopicalDMSOappears
tobeasafeandeffectivetreatmentforthecancerrelated
condition,anthracyclineextravasation5.
NumerousdrugsdissolvedinDMSOretaintheirtherapeutic
activityandtheirspecificpropertiesoveralongperiodoftime.
DMSOnotonlymaintainsbutstrengthensandmultipliesthe
actionofthedrugsdissolvedinit,thuspermittingthe
administrationoflowerdosesthannormallyrequiredtoobtaina
satisfactoryresponse.Inorganbanksaroundtheworld,organs
andtissuesarestoredandpreservedinDMSOsothattheyare
availablefortransplantingandgrafting.Tissuessuchasred
bloodcorpusclesfortransfusionsandsemenforartificial
inseminationarepreservedinthismanner.
Asapenetratingcarrierofdrugs,DMSOisunsurpassed.It
easilycarriesnecessarypharmaceuticalstoanypartofthebody
fortherapeuticeffect.Itpassesthroughcellularmembranes
andtissues.Itisforthisreason,amongmanyothers,that
DMSOisproperlydescribedlessasadrugbythoseintimate
withit,moreasanewandlittleunderstoodtherapeutic
principle.AsDrJacobsreportedtoanassemblyoftheAmerican
CollegeofAdvancementinMedicine,DMSOismoreeffective
whenusedinconjunctionwithothermedicationswhichitcan
deliverthroughoutthebodywithspectacularease.Thiscan
occurevenwhenDMSOisappliedtopically,andtheother
medicationingestedorallyorintravenously.
Forinstance,DMSOwillcarryhydrocortisoneor
hexachloropheneintothedeepestlayersoftheskin,producing
areservoirthatremainsforsixteendaysandresistsdepletion
bywashingtheskinwithsoap,wateroralcohol.DMSOmixed
withhydrogenperoxide9%solutionhasprovenhighlyeffective
inthetreatmentoforalandgenitalherpeswhenapplied
topicallytotheaffectedareas.Periodicoutbreaksofthevirus
havebeenknowninmanycasestoceasealtogetherwith
regularapplication.
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AninterestingobservationisthattheapplicationofDMSOto
oneaffectedjointorareaoftenleadstopainreliefinsome
otherlocation.DMSOhassystemiceffects.Itisadepressantto
thecentralnervoussystemand,ofcourse,itreachesallareasof
thebodywhenabsorbedthroughtheskinandintothe
bloodstream.
PerhapstheeffectDMSOhashadonthelivesofcountless
thousandsmaybesummedupbythecaseofRuthLewisof
Sarasota,Florida.Ruth,agedsixtyfour,wasinsomuchpain
fromrheumatoidarthritisthatshecouldntwalkwithouttheaid
ofafourleggedwalkingdevice.Painhadbeenherconstant
companionforovertwentyyears.Whensherecentlysustained
abackinjury,shewastoldbyherphysicianstohaveatleastsix
monthstotalbedrest.
Realisingthatthiscouldspelltheendofherwalkingdaysfor
ever,thedeterminedRuthhadhersonandhusbandphysically
carryherintotheDouglasspreventativemedicineclinicin
Marietta,GeorgiatoundergoacourseoftreatmentwithDMSO.
Ihadpreviouslyexperiencedmanymonthsofseverepainin
myhipsandlegs,visitingspecialists,diagnosticclinics,
hospitalisationintractionandotherprocedures,saidRuth.
WhenIenteredthedoctorsofficeforDMSOtreatment,Iwas
unabletoputbothfeetontheground.Aftertwoandahalf
weeksofintravenousDMSOtreatment,Iwalkedoutofthat
officewithoutanyhelpwhatsoevernocanenosupportatall.
Ihadnotbeenabletoclosemyrighthandcompletelyforover
ayear.Itevenkeptmeawakeatnightwithseverepain.But
aftertheIV,topicalandoralDMSOtreatment,Icannowclose
myhandtightly.Thearthritishasnotreturned.
Icannotputintowordswhatthisdrughasdoneforme.I
highlyrecommendit.Isawmanypeoplecomeandgoduring
mystayallwalkedoutwell.
Logged
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G.I.Gurdjieff
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