STROBE Statementchecklist of items that should be included in reports of observational studies
Item
No Recommendation
Title and abstract 1 (a) Indicate the studys design
with a commonly used term in
the title or the abstract
(b) Provide in the abstract an
informative and balanced
summary of what was done and
what was found
Introduction
Background/rationale 2 Explain the scientific
background and rationale for the
investigation being reported
Objectives 3 State specific objectives,
including any prespecified
hypotheses
Methods
Study design 4 Present key elements of study
design early in the paper
Setting 5 Describe the setting, locations,
and relevant dates, including
periods of recruitment,
exposure, follow-up, and data
collection
1
a. Tidak dijelaskan design studi
pada judul dan abstrak
b. Terdapat rangkuman yang
seimbang dan informatif
Dijelaskan pada introduksi bahwa kanker
rahim merupakan keganasan yang ke 6
yang paling terjadi yang telah menyerang
287100 orang pada 2008, dimana 80-
90% merupakan adenokarsinoma
endometrium. FIGO telah
merekomendasikan prosedur oprasi yang
didalamnya terdapat pula pembedahan
pada nodus limfa di pelvis. Sedangkan
belum ada consensus yang jelas
mengenai perlu atau tidak pembedahan
nods limfa di pelvis atau nodus limfa
para aorta.
Tujuannya adalah untuk mengidentifikasi
factor resiko klinikopatologikal dari
metastasis PLN dan untuk mengevaluasi
perlunya tindakan limfadenektomi pelvis
pada fase awal dari karsinoma
endometrium,
Penelitian ini menggunakan studi
restrospekstif
Penelitian dilakukan di Institutional
Review Board of Fudan University,
Obstetrics and Gynecology Hospital,
Shanghai, China. Tahun 1989 sampai
2006 di Obstetrics and Gynecology
Hospital of Fudan University.
Participants 6 (a) Cohort studyGive the Pada paragraph 2 bagian bahan dan
eligibility criteria, and the metode dijelaskan criteria inklusi dan
sources and methods of eksklusi. Partisipan didapatkan dari
selection of participants. pasien yang telah melakukan operasi
Describe methods of follow-up adenokarsinoma endometrium di bagian
Case-control studyGive the obsgyn Hospital of Fudan University
eligibility criteria, and the
sources and methods of case
ascertainment and control
selection. Give the rationale for
the choice of cases and controls
Cross-sectional studyGive the
eligibility criteria, and the
sources and methods of
selection of participants
(b) Cohort studyFor matched Kontrolnya adalah pasien yang tidak
studies, give matching criteria terdapat metastasis PLN
and number of exposed and
unexposed
Case-control studyFor
matched studies, give matching
criteria and the number of
controls per case
Variables 7 Clearly define all outcomes, Tidak dijelaskan
exposures, predictors, potential
confounders, and effect
modifiers. Give diagnostic
criteria, if applicable
Data sources/ 8* For each variable of interest, Tidak dijelaskan
measurement give sources of data and details
of methods of assessment
(measurement). Describe
comparability of assessment
methods if there is more than
one group
Bias 9 Describe any efforts to address Tidak dijelaskan
potential sources of bias
Study size 10 Explain how the study size was Tidak dijelaskan
arrived at
Quantitative 11 Explain how quantitative Tidak dijelaskan
variables variables were handled in the
analyses. If applicable, describe
which groupings were chosen
and why
Statistical methods 12 (a) Describe all statistical Tidak dijelaskan
methods, including those used
to control for confounding

2
 (b) Describe any methods used Tidak dijelaskan
to examine subgroups and
interactions
(c) Explain how missing data Tidak dijelaskan
were addressed
(d) Cohort studyIf applicable, Tidak dijelaskan
explain how loss to follow-up
was addressed
Case-control studyIf
applicable, explain how
matching of cases and controls
was addressed
Cross-sectional studyIf
applicable, describe analytical
methods taking account of
sampling strategy
(e) Describe any sensitivity
analyses

Results
Participants 13* (a) Report numbers of Terdapat 621 yang melakukan tindakan
individuals at each stage of pembedahan PLN dan 8 pembedahan
studyeg numbers PALN. Terdapat 24 pasien yang terbukti
potentially eligible, terdapat metastasis di PLN dan tidak ada
examined for eligibility, pasien yang terbukti terdapat metastasis
confirmed eligible, included PALN
in the study, completing
follow-up, and analysed
(b) Give reasons for non- Tidak dijelaskan lebih lanjut
participation at each stage
(c) Consider use of a flow Tidak terdapat
diagram
Descriptive data 14* (a) Give characteristics of Dijelaskan pada tabel 1
study participants (eg
demographic, clinical,
social) and information on
exposures and potential
confounders
(b) Indicate number of Tidak terdapat
participants with missing
data for each variable of
interest
(c) Cohort study Follow-up dilakukan rata-rata 63,7 bulan
Summarise follow-up time (0,5-174 bulan)
(eg, average and total
amount)

3
Outcome data 15* Cohort studyReport penelitian mengambil data pasien dari
numbers of outcome events tahun 1989 hingga 2006 untuk dianalisis
or summary measures over dan follow up
time
Case-control studyReport
numbers in each exposure
category, or summary
measures of exposure
Cross-sectional study
Report numbers of outcome
events or summary measures
Main results 16 (a) Give unadjusted a. Disebutkan dalam tabel 3 bahwa
estimates and, if applicable, CI 95% sehingga jurnal ini bias
confounder-adjusted dipercayai engan analisis
estimates and their precision multivariat
(eg, 95% confidence
interval). Make clear which
confounders were adjusted
for and why they were
included
(b) Report category Tidak dijelaskan
boundaries when continuous
variables were categorized
(c) If relevant, consider Tidak dijelaskan
translating estimates of
relative risk into absolute
risk for a meaningful time
period
Other analyses 17 Report other analyses done Dijelaskan pada tabel 4
eg analyses of subgroups
and interactions, and
sensitivity analyses
Discussion
Key results 18 Summarise key results with Todo et al menjelaskan bahwa
reference to study objectives pembedahan pada PALN tidak bias
menunjukkan keuntungan pada pasien
dengan resiko yang rendah
Limitations 19 Discuss limitations of the Pada paragraph dua bagian diskusi
study, taking into account dijelaskan bahwa keterbatasan penelitian
sources of potential bias or ini hanya terdapat 8 pasien yang
imprecision. Discuss both melakukan tindakan PLN dan PALN yang
direction and magnitude of mengakibatkan dari 8 kasus tersebut tidak
any potential bias bias menunjukkan adanya metastasis di
jaringan limfa para aorta dan mengenai
apakah perlu diseksi PALN dilakukan pada
fase awal kanker endometrium belum
dilakukan oleh peneliti.

4
Interpretation 20 Give a cautious overall Tidak terdapat jurnal pembanding
interpretation of results
considering objectives,
limitations, multiplicity of
analyses, results from
similar studies, and other
relevant evidence
Generalisability 21 Discuss the generalisability Tujuan dari limpadenektomi pada tahap
(external validity) of the awal kanker tidak hanya digunakan untuk
study results mengetahui luasnya penyakit, tetapi juga
untuk mengetahui prognosis penyakit
tersebut. Meskipun metastasis pada PLN
masih belum menyebar luas pada fase
awal, tingkat harapan hidup pasiennya
lebih rendah 5 tahun. Dalam penelitian ini,
invasi dari adenokarsinoma yang telah
menembus bagian dalam endometrium dan
LVSI menjadi criteria prediktif utama
kejadian metastasis PLN.
Other information
Funding 22 Give the source of funding Tidak dijelaskan sumber pendanaan
and the role of the funders penelitian
for the present study and, if
applicable, for the original
study on which the present
article is based

*Give information separately for cases and controls in case-control studies and, if applicable, for exposed and
unexposed groups in cohort and cross-sectional studies.

Note: An Explanation and Elaboration article discusses each checklist item and gives methodological background and
published examples of transparent reporting. The STROBE checklist is best used in conjunction with this article (freely
available on the Web sites of PLoS Medicine at http://www.plosmedicine.org/, Annals of Internal Medicine at
http://www.annals.org/, and Epidemiology at http://www.epidem.com/). Information on the STROBE Initiative is
available at www.strobe-statement.org.