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Bones:
1. Anatomical structures
a. Provide rigid framework for the trunk and
extremities
b. Locomotor function
c. Protect vulnerable viscera
2. Physiological organ
a. Hemopoietic tissue (RBC, granular leukocytes,
platelets)
b. Reservoir of Ca, Phosphor, Mg, Na.
Ossification:
At the time of the birth distal femoral epiphysis forms the secondary
center of ossification, provides growth in the length of the bone.
1. Resting cartilage
2. Young proliferative cartilage
3. Maturing cartilage
4. Calcifying cartilage
Immature bone: first type of bone, never seen under normal condition
after 1 year. Exception: fracture healing, reaction to an infection, tumor.
Biochemistry of bones:
PTH actions:
Calcitonin actions:
Classification:
Anatomical structure:
Histological structure:
Similarity:
Differences:
Bone: Cartilage:
Collagen type I Collagen type II
Highly vascular Poorly vascular
Matrix are calcified
Synovial fluid:
Dyalisate of plasma
Clear, yellowish, vicous fluid
Contain glycoprotein and lubricant hyaluronic acid
Nourishing and lubricating joint
Adult: <5mL
Also contain in synovial burse and tendon sheath
Total cell count < 200/mL, predominantly MN macrophages &
lymphocytes
No fibrinogen thats way it wont clot