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ABSTRACT
The use of plants as medicines predates written human history. Ethnobotany (the study of
traditional human uses of plants) is recognized as an effective way to discover future medicines.
In 2001, researchers identified 122 compounds used in modern medicine which were derived
from "ethnomedical" plant sources; 80% of these have had an ethnomedical use identical or
related to the current use of the active elements of the plant. The plant is a biosynthetic
laboratory, not only for chemical compounds, but also a multitude of compounds like glycosides,
alkaloids etc. These exert physiological and therapeutic effect. Plants can provide biologically
active molecules and lead structures for the development of modified derivatives with enhanced
activity and reduced toxicity. The small fraction of flowering plants that have so far been
investigated have yielded about 120 therapeutic agents of known structure from about 90
species of plants. According to one estimate only 20% of the plant flora have been studied and
60%of synthetic medicines owe their origin to plants. The medicinal values of many plants have
been established and published, but most of them are waiting to be explored till date. Therefore,
there is every need to find their uses and to conduct pharmacological studies to discover their
medicinal properties .Canna Indica (L.) is a spreading annual herb found throughout India but
unfortunately it is one of the neglected plants. Hence, the present review aims to open new
avenues for the improvement of medicinal use of Canna Indica for various ailments and to bring
the anti-diabetic Medicinal plant to the scientists notice, and raise awareness and add value to
the resource. This review attempts to highlight the available literature on Canna Indica (L.) with
respect to ethno botany, chemical constituents and summary of various pharmacologic
activities.
INTRODUCTION
Indian medicinal plants are the essence of are red or yellow and showy. It encloses a
Ayurveda and Ayurvedic treatments. When variable number of round, shiny black seeds.
used judicially and clocking with the basic In folkloric medicine, root decoction is used for
principles they produce miraculous effects. the treatment of fever, dropsy, and dyspepsia.
Their role cannot be confined to mere curative Seed juice is used to relieve ear aches. The
of disease but they also used being of human flowers are said to cure eye diseases1,2. The
body. Hence, Ayurvedic drugs are rightly leaves of C. indica showed a significant
called the elixirs of life. Ayurvedic Herbs analgesic activity and the rhizomes showed a
played important role in Ayurvedic treatment, good anthelmintic activity against Pheritima
from ancient time to this most modern time. posthuma3. Canna indica sps. Can be used
Medicinal plants have been identified and for the treatment of industrial waste waters
used throughout human history. Plants have through constructed wetlands. It is effective for
the ability to synthesize a wide variety of the removal of high organic load, color and
chemical compounds that are used to perform chlorinated organic compounds from paper
important biological functions, and to defend mill wastewater.4, 5 Archaeological evidence
against attack from predators such suggests that Canna indica L. was one of the
as insects, fungi and herbivorous mammals. first plants to be cultivated during incipient
Canna indica L. (also known as saka siri, civilization of Peru and Argentina 6. Today, it is
Indian shot) is a species of the Canna genus, used in medicine, and its starchy rhizome is
belonging to the family Cannaceae. Indian used in nutrition. Paper is made from the
shot or canna represents an important floral fibers of its leaves and stems. The seed is
material of all urban areas. It is often planted used in jewelry making, and it used to be used
in large areas, such as squares, areas along instead of rifle bullets. Purple color is obtained
roads, parks and green spaces in front of from the seeds. Young seeds and young
representative buildings in order to get strong shoots can be used in nutrition 7. The fibers
effects. Canna indica L. (Cannaceae) is obtained from stems are used as a substitute
commonly known as an Indian shot or Canna for jute. This plant has a large biomass
lily. Several varieties are common all over production and in some countries is used for
India and are grown in gardens. A medium thermal energy production i.e. as biofuel 8. It
sized species; green foliage, oblong shaped, can produce high biomass in different soils
spreading habit; triangular flower stems, and especially in the aquatic environment. In
coloured green; spikes of flowers are erect, addition to its exceptional decorativeness and
self-coloured red, staminodes are long and wide application, Canna indica L. is also very
narrow, edges regular, petals red, partial self- important for phytoremediation because it can
cleaning; fertile both ways, self-pollinating and successfully remove heavy metals and other
also true to type, capsules globose; rhizomes pollutants from soil and water. By deposition of
are thick, up to 3 cm in diameter, coloured various pollutants from the air (dioxins,
purple; tillering is prolific. It is an upright polycyclic aromatic hydrocarbons and
perennial rhizomatous herb up to 5 feet high, polychlorinated biphenyls) on leaves with
whose leaves are fleshy with thinner margins, large surface areas canna indica L. can
usually not more than 1 foot long and half as remove this serious pollutants from the
broad, lanceolate to sub-orbicular. The flowers atmosphere 9.
CLASSIFICATION
VERNACULAR NAMES
theca 0.51.2 cm long; style red to yellow, free beads in natural seed jewellery for necklaces
part linear to club-shaped, 1.54.5 by 0.10.3 and especially rosaries The most common
cm. Fruit bright green, covered by green to use of the Canna by Europeans and North
purple tubercles, ellipsoid to subglobose or Americans is as an ornament. The seeds are
obovoid, 1.54(5.5) by 1.52(3.5) cm. Fruits used as beads in some countries, or in gourds
are capsules, green oblong-ovoid, soft to form rattles. The rhizomes are used to
,echinate (spiny), and 2 to 2.5 centimeters make a form of arrowroot. The particular
long. Seeds are about the size of a pea, starch made from the roots of Canna indica is
somewhat spherical, with shining, black seed- known as "tous-les-mois" in the West Indies,
coat. Seeds subglobose, 48 mm diameter. and as the Queensland Arrowroot in Australia.
The dark, shiny seeds can be drilled and used The rhizomes have also been used in India as
as beads in seed jewellery or strung into leis. a diaphoretic, diuretic, in fevers and dropsy,
The seeds are also used in hula rattles. and as a demulcent, stimulant. Indians have
used stalks cut into pieces and boiled with rice
ECOLOGY AND POLLINATION BIOLOGY water and pepper given to cattle as antidote
Cannas are found scattered in transitional for effects produced by eating poisonous
habitats, both natural and artificial. In the wild grasses. Rhizome may be collected during
they grow along the edges of marshes and any time of the year..Ethanol (50%) extract of
forest margins, often in water up to 10 cm the aerial parts is hypotensive; tuber exhibited
deep. They also thrive in spoil banks, roadside enterokinase activity. Unsaponifiable matter of
ditches and refuse sites given adequate the plant is molluscidal (Asolkar et al., 1992).
moisture and seasonal drought. Seeds
germinate and produce reproductive shoots in PROPERTIES
a single growing season (less than 4 months), Sweet-tasting, slightly cooling-natured,
generally flowering mid to late rainy season. antipyretic, relieves gastrointestinal disorders.
Some studies indicate these flowers might be Rhizomes considered demulcent, diaphoretic,
pollinated by hawk moths. However, pollen is diuretic, antipyretic.Seeds considered cordial
shed before the flowers open, resulting in self- and vulnerary. Roots considered acrid and a
pollination. Indeed, greenhouse grown plants stimulant.
set seed readily, even in the absence of any
likely pollinator. The coloration and floral tube CHEMICAL CONSTITUENTS
of some (C. jaegeriana, C. paniculata, and C. Rootstock contains enzymes, triacontanol and
tuerkheimii) suggest hummingbird pollination. mixture of stigmasterol, -sitosterol,
A variety of insects including bees, moths and campesterol and - lectin and traces of
butterflies, as well as hummingbirds, have alkaloids (Asolkar et al. 1992; Ghani,
been observed visiting Canna flowers, 2003).From the red flowers of Canna indica
presumably to collect the nectar which (Cannaceae) four anthocyanin pigments have
accumulates at the base of the floral tube. been isolated apart from quercetin and
Seed dispersal is likely unassisted due to the lycopene. They are Cyanidin-3-O-(6''-O--
large seed size and lack of reward for rhamnopyranosyl)-- glucopyranoside(11),
potential animal dispersal agents. (Kubitzki, Cyanidin-3-O-(6''-O--rhamnopyranosyl) --
12
1998). galactopyranosid , Cyanidin-3-O--
glucopyranoside13and yanidin-O--
14
PARTS USED galactopyranoside . These compounds were
A type of starch is made from the rhizomes isolated by using HPLC and their structures
that is very similar to, and a good substitute were subsequently determined on the basis of
for, arrowroot starch which is derived from an spectroscopic analyses, i.e., (11)H NMR, C
unrelated plant, Maranta arundinacea. The NMR, HMQC, HMBC, ESI-MS, FTIR, UV-
young rhizomes of Indian shot are sometimes Visible etc. The isolated compounds showed
eaten; they are sweet, but woody and fibrous. good antioxidant activity thus makes it suitable
The seeds are perfectly round and very hard for use in food coloration and as a
and reportedly were used as shot for flintlock nutraceutical. Thus it is a promising pigment
muskets when lead shot was not available. source for food applications.Canna indica was
Nowadays the seeds are commonly used as found to contain terpenes, paraffin
hydrocarbons and a toxic red oil termed can- fevers, dropsy and dyspepsia. Seeds are
nabinol as the major chemical constituents 15. cordial and vulnerary. Seed juice relieves
The flowers of Canna indica are brightly red. earaches. Root bark and stalks are used to
The appearance of red color is due to the the cattle suffering from poisoning.Rhizome is
presence of flavonoids, phenols and used in ringworm in Khagrachari. The
anthocyanins 16.The biological activities of rhizomes contain ethereal oils, waxes, and a
flavonoids have been extensively reviewed. diuretic (diuresin;). They are used as a
Some of them have been found to possess febrifuge (diaphoresin;), against dropsy
anti-ischemic, anti-platelet, anti-inflammatory (hydropsia;), against fever , in softening
and anti-lipoperoxidant activities. Flavonoids compresses in tandpowder , and as a
have also been found to inhibit a wide range stimulant . A decoction of the rhizome is used
of enzymes involved in oxidation systems to treat gonorrhoea (antiblennorrhagia) and
such as cold of the bladder . A decoction of the stems
lipoxygenase,cyclooxygenase,monooxygenas is used as a drink or bath to regain energy.
e, or xanthine oxidase.These biological The leaves are used for wrapping up parcels
activities are related to their antioxidative in Asia (Ridley 1924) as well as in Panama,
effects.17.As flavonoids, anthocyanins are and to wrap around tamales (pastries made of
present in flowers of Canna indica and are pH corn filled with beans, meat, and pepper;),
sensitive 18. they are fed to animals, and have sometimes
been eaten as legume by the poor (Brazil).
PHARMACOLOGICAL ACTIVITY Smoke of burned leaves can be used as
Canna indica sps. can be used for the insecticide (Kraenzlin 1912: 15; greenhouse
treatment of industrial waste waters through America). Freshly squashed leaves are used
constructed wetlands. It is effective for the in baths against rheumatic pains and arthritis
removal of high organic load, color and and are applied to ulcers. Juice of leaves is
chlorinated organic compounds from paper used against mercurials as a diuretic, and in
mill wastewater. The plant is used in traditional compresses .Leaf extracts have shown
medicine and the rhizome is used in traditional molluscicidal activity (to kill snails, Rogers
foods. 1984). The juice of unripe fruit is used against
inflammation of the ear .The fruit can be used
Folkoric to treat constipation of children, and they yield
In Bangladesh, paste of plant used for a purple dye which is not permanent. The
tonsillitis.In Thailand, rhizome has been used seeds are used as ammunition for blowpipes,
with other herbs for cancer treatment. In in musical rattles as beads for making rosaries
southwest Nigeria, leaves used for (Indonesia, India, West Indies), as beads to
malaria.Principally used in the treatment of make necklaces and bracelets after boiling as
acute jaundice type of hepatitis.Use 15 to 30 toys, as ammunition for childrens shotguns or
gms dried material or 60 to 90 gms fresh as a substitute for lead in hunting .They also
rhizome material in decoction. Commonly, have been used as an ingredient or a
recovery from jaunditic symptoms may be substitute for coffee (Brazil, Europe).
observed after one week of administration. In
the Philippines, decoction of rhizome used as STUDIES
diuretic. Also, when macerated in water, used AIDS / HIV1-RT Inhibition: Canna indica was
to alleviate nosebleeds. In Costa Rica infusion one of twenty Thai medicinal plants used to
of leaves used as diuretic; rhizomes used as treat AIDS tested for their HIV type 1 reverse
emollient. Decoction of rhizomes used in transcriptase inhibitory activity. C. indica
fevers, dropsy and dyspepsia.Flowers may be rhizomes showed HIV-1 RT inhibition ratio
used for external wound bleeding use 10 to higher than 90% at 200 bug/ml concentration.
15 gm dried material in decoction. In folkloric Further study of C .indica and two proteins
medicine, root decoction is used for the isolated showed significant HIV-1 RT
treatment of fever, dropsy, and inhibition19.
dyspepsia.Seed juice is used to relieve Cannagenin / Molluscicidal: Study yielded
earaches. Root is diuretic, diaphoretic, cannagenin, which had a highly synergistic
stimulant and demulcent; decoction is used in with chlorophyll on the morality of snails21.
Study showed C indica to have time and dose 1. The plant yields a fiber - from the stem - it
dependent mollusicidal activity in a dose that is a jute substitute28.
was not toxic for the fish Colisa fasciatus, 2. A fiber obtained from the leaves is used
which shares the same habitat as the snail L for making paper29. The leaves are harvested
acuminate.21 in late summer after the plant has flowered,
Hepatoprotective: Study showed the they are scraped to remove the outer skin and
methanol extract of aerial parts of Canna are then soaked in water for 2 hours prior to
indica has liver protective effect against cooking. The fiber are cooked for 24 hours
carbon tetrachloride-induced hepatotoxicity. with lye and then beaten in a blender. They
Study of hydroalcoholic extract showed make a light tan brown paper29.
3.
significant antioxidant and hepatoprotective A purple dye is obtained from the seed28.
activity. Results were compared with reference 4. Smoke from the burning leaves is said to
drug Silymarin22. be insecticidal30.
Cytotoxicity / Anticancer: Study yielded two
pure compounds, stigmasteril and 6-beta- CONCLUSION
hydroxystigmasta-4, 22-diene-3-one and two
other toxic minor components. They showed Canna indica (L.) is a well known plant with
cytotoxicity against P388 leukemia cells23. less known scientific data. Each and every
Antioxidant: Study results clearly indicate the part of it is useful having medicinal activity.
aerial parts of C indica is effective in India is home to a variety of traditional
scavenging free radicals and has the potential medicinal systems that rely to a very large
to be a powerful antioxidant 23,26. extent on native plant species for their raw
Flower Anthocyanins / Antioxidant / Pigment drug material. The folkoric medicinal value
Source: Study of red flowers of Canna indica imparts tremendous value to this herb. The
isolated anthocyanins. Four anthocyanin qualitative analysis revealed the presence of
pigments were isolated from quercetin and the biomolecules such as flavonoids, phenolic
lycopene. The compounds showed good compounds, saponins, steroids, tannins and
antioxidant activity. Results suggest a terpenoids. The studies on plant Canna indica
promising pigment source for food (L.),also desire development of novel
applications25. therapeutic agents from the various types of
The plant is used in the treatment of women's chemicals with various pharmacologic
complaints27. properties isolated from it. Therefore, there is
A decoction of the root with fermented rice a wide scope for research in the direction of
is used in the treatment of gonorrhoea and more medicinal activities of plant and to
amenorrhoea27. evaluate the pharmacological actions of the
The plant is also considered to be same in coming future.
demulcent, diaphoretic and diuretic27.
USES
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