BIRLA INSTITUTE OF TECHNOLOGY AND SCIENCE, PILANI HYDERABAD CAMPUS

FIRST SEMESTER 2014-2015

General Biology (BIO F111)
Comprehensive Examination (Closed book)
Part B (Short Answer type)
Time 60 min 05/12/2014 30 Marks

Name: ID:

ID: Section No.: Instructors name:

Instruction: Write you final answer in space provided. Avoid overwriting. Do rough work at last page.
1 State with reasons, whether the following are true or false? (Note: no marks will be awarded without reason)
a) Mitrochondria is found in all prokaryotic cells, except photosynthetic bacteria. 6X1.5

b) Mitrochondria contains ribosome.

c) The endoplasmic reticulum forms many folds and convolutions within the space inside mirochondria

d) In nucleic acids the total purine content of RNA is always equal to the total pyrimidine content.

e) The extra-chromosomal DNA present in many bacteria is single-stranded.

f) Carbohydrate is stored as lactose in the mammary gland.

2 The molecular wt of a bacterial DNA molecule is 1.32 x 109. The average molecular wt of a nucleotide pair is 660
and each nucleotide pair contribute 0.34nm to the length of the DNA.
a) Calculate the length of the bacterial DNA molecule. 3M

b) Assume that average protein consists of a chain of 300 amino acids. What is the maximum number of 3M
proteins that can be coded by the bacterial DNA molecule?

3 Write the name of two proteins involved in the replication and note their specific function. 2M

4 How many different gamete genotypes will be produced by the following parental genotypes, if all genes shown 3M
are not linked. (Note: If no. of possible gamete genotypes is more than 10, write only no. of genotypes in the
gametes)
a) AA

b) Aa

c) AaBB

d) AaBb

e) AAbbCc

f) AaBbCcDdEe
5 In cats the genotype BB is black, Bb is tortoise shell and bb is yellow. The gene is on the X-chromosome. A
tortoise shell female is crossed with a black male.
a) What offspring would be expected from this crossing? 3M

b) Would you expect to find any tortoise shell males? Why? 2M

6 Label the following diagram according to given instructionnle 5M