Preparation No.

12
Calcium Hydroxide Topical Solution PROCEDURE:
Official, External, USP 31 1. Slake CaO for 5 mins.
(place in mortar or evaporatin dish,
Formula sprinkle with 3-5 gtts of water, cover
Ingredients OA CA with watch glass. Let it stand for 5
CaOH 3g 0.09g mins.)
Water, qs ad 1000mL 30mL
2. Add 30 mL cold water
3. Agitate for 30 mins in an ice bath
Slaking
4. Filter, collect filtrate
CaO + 5gtts H2O -> Ca(OH)2
5. Transfer in container (liniment bottle)
56g/mol 74 g/mol

X:56g/n :: 0.09g:74g/n 6. Add cold water up to the brim

X= 0.07 g of CaO
**there should be no bubbles in bottle because
it indicates presence of carbon dioxide.

STIR FOR 15 mins. Ca(OH)2 + CO2  CaCO3 (white ppt)

WHY??
USES:
--to increase the solubility of CaOH in water
 Astringent
**avoid too much exposure to air
 Protective
AVOID BUBBLES??
Hydrogen + O2
Calcium hydroxide is less soluble in hot water
we were preventing the formation of CaCO3
than cold so cold purified water is the solvent.
(white precipitate)
SYNONYMS:
 lime water
FINAL RESULT:
 Liquor calcis
Clear solution, no bubbles inside your bottle.
CONTAINER && STORAGE:
Add enough cold water up the brim of the
Soln shoud be stored in well-filled, tightly
container.
stappered containers to detor te absorption of
CO2 & should be kept in a cool place to
maintain an adequate concentration of
dissolved solute, white clear solution.
Preparation no 13
Strong Iodine Solution USES:
Official, external, USP 31  Antiseptic
 Disinfectant
FORMULA Solubilizing agent
Ingredients OA CA - Converts iodine to triiodocomplex form
Iodine 50g 1.5g
which is more water soluble
KI 100g 3g=3mL
Water, qs ad 1000mL 30mL PHYSICAL APPEARANCE:
Like Betadine.
PROCEDURE
1. Dissolve KI in 2.5 mL of p.H2O
2. Dissolve Iodine crystals in KI soln
3. Add sufficient amt of H2O to obtain
15mL.

SYNONYMS:
 Lugol’s solution

METHOD OF PREPN:
 Simple solution Method
Potassium Iodide or sodium iodide
- Used as solubilizing agent for iodine

PREACUTION:
1. Do not use stainless spatula bec iodine
is very corrosive & reactive, use the
porcelain instead.
2. Watch glass should be used in weighing
3. Avoid holding the iodine crystals bec it
would stain your hands & jewelries.
Solubility of 1g of I2 will be dissolved in 2950 mL
H2O ; it is very slightly soluble.