package biochem;

import java.util.Scanner;

public class Biochem {

public static void main(String[] args) {

Scanner input=new Scanner(System.in);

double s1=0.0032, r1=0.111;

double s2=0.0049, r2=0.143;

double s3=0.0062, r3=0.148;

double s4=0.0080, r4=0.166;

double s5=0.0095, r5=0.200;

double Ex,Ey,Ex2,Exy;

double EX,EY,EX2,EXY;

System.out.println("\n\nEvaluate Michaelis-Menten parameters by:");

System.out.println("A: Lineweaver-Burk");

System.out.println("B: Eadie-Hofstee");

System.out.print("\nInput Choice: ");

String Equation=input.next();

switch (Equation)
{case "A":

System.out.println("Lineweaver-Burk");

double x1,x2,x3,x4,x5,y1,y2,y3,y4,y5;

x1=1/s1; y1=1/r1;

x2=1/s2; y2=1/r2;

x3=1/s3; y3=1/r3;

x4=1/s4; y4=1/r4;

x5=1/s5; y5=1/r5;

Ex=x1+x2+x3+x4+x5;

Ey=y1+y2+y3+y4+y5;

Ex2=Math.pow(x1,2)+Math.pow(x2,2)+Math.pow(x3,2)+Math.pow(x4,2)

+Math.pow(x5,2);

Exy=((x1*y1)+(x2*y2)+(x3*y3)+(x4*y4)+(x5*y5));

double m=((5*Exy)-(Ex*Ey))/((5*Ex2)-(Math.pow(Ex,2)));

double b=((Ey*Ex2)-(Ex*Exy))/((5*Ex2)-(Math.pow(Ex,2)));

double rmax=1/b;

double km=m*rmax;

System.out.printf("\nkm = %1.4f",km);

System.out.printf("\nrmax = %1.4f",rmax);

System.out.println(" ");
break;

case "B":

System.out.println("Eadie-Hofstee");

double X1,X2,X3,X4,X5,Y1,Y2,Y3,Y4,Y5;

X1=r1/s1; Y1=r1;

X2=r2/s2; Y2=r2;

X3=r3/s3; Y3=r3;

X4=r4/s4; Y4=r4;

X5=r5/s5; Y5=r5;

EX=X1+X2+X3+X4+X5;

EY=Y1+Y2+Y3+Y4+Y5;

EX2=Math.pow(X1,2)+Math.pow(X2,2)+Math.pow(X3,2)+Math.pow(X4,2)

+Math.pow(X5,2);

EXY=((X1*Y1)+(X2*Y2)+(X3*Y3)+(X4*Y4)+(X5*Y5));

double M=((5*EXY)-(EX*EY))/((5*EX2)-(Math.pow(EX,2)));

double B=((EY*EX2)-(EX*EXY))/((5*EX2)-(Math.pow(EX,2)));

System.out.printf("\nkm = %1.4f",-M);

System.out.printf("\nrmax = %1.4f",B);

System.out.println(" ");

break;
 default:

System.out.println("Application Error!");