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Against Cytoki Infections- Carica papaya Linn. Int J clinical & case. 1:7, 140-144
Keywords: Ischemic Stroke, Post-Stroke Depression, Cerebral Hemodynamic, Bioelectrical Activity of the Brain, Melitor
Introduction
H1N2 viruses have an avian-like SIV H1N1 haemagglutinin (HA) and sented in this thesis support the observations concerning the con-
a European H3N2 SIV-like neuraminidase (NA). Nucleotide sequence tinuous reassortment processes of SIVs in pigs, resulting in repeat-ed
comparison revealed significant differences between the two and independent emergence of certain HA/NA combinations. This
consecutive H1N2 isolates. To be able to understand the geno-typic may lead to emergence of new viral variants of severe patho-genicity
differences observed in the genomes of these H1N2s, and to identify of pigs. Continuous and efficient surveillance and further detailed
the genetic markers responsible for the differences, a re-verse genetic genetic and phenotypic analysis can help to identify such novel
system was developed. Four recombinant SIV H1N2 viruses were viralvariants, having more potential to cross species barriers and to
constructed that displayed differences in virulence in mice, r1021 pose health risks even tohumans and to other host species A
(morevirulent) and r9706 (less virulent), as well as the same viruses disturbing trend in antimicrobial-antiviral resistance is the ad-vent of
with swapped PB1 segments. Interestingly, the current findings superbugs which often complicates the treatment of flu-
showed that the replacement of the PB1segment of r9706 by that of immunocompromised patients. To this must be added the nu-merous
r1021 increases the virulence of the virus that replicate with higher hospitalizations and increased morbidity from contaminat-ed meats,
titer in mice lungs, while the opposite is true when PB1 r9706 is vegetables, seafoods, and dairy products.
introduced into r1021. This study demonstrates that differences in Many of the emerging types of avian flus [e.g. H1N1, H2N2,
virulence of swine influenzavirus subtype H1N2 are attributed at least H3N2, A(H10N8) ] have a very serious hemorrhagic component to
in part to the PB1 segment. The findings pre- them which complicates effective treatment. Any new, effective
International Journal of Case Studies in Clinical Research Volume 1 Issue 7, November 2017
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