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Hepcinat-lp tablets can be made available mumbai, kolkata, hyderabad, chennai, ahmedabad,
delhi, bangalore and pune and other cities in india"
Benefits
Hepcinat-lp tablets is a formulation combination of anti-viral medications ledipasvir and
sofosbuvir used in the treatment of chronic hepatitis c virus (chcv) infection genotype 1.
Hepcinat-lp is a prescription medicine containing ledipasvir (90mg) a viral ns5a inhibitor and
sofosbuvir (400mg) a nucleotide inhibitor of the viral rna polymerase.
The international brand name of this medicine is harvoni that provides effective treatment in
hepatitis c genotype 1 with a cure rate ranging between 94% to 99%. Hepcinat-lp helps prevent
hepatitis c virus infection from multiplying in your body by weakening the virus and inhibiting its
reproduction and replication.
Side effects
Hepcinat-lp's active ingredients are ledipasvir & sofosbuvir which may have reported side effects
as under:
common side effects / symptoms - consult your doctor or medical practitioner if you experience
any common side effects or symptoms such as nausea, diarrhea, headache, loss of appetite,
lower back pain, side pain, insomnia (sleeplessness) and/or fever.
serious side effects / symptoms - discontinue use of hepcinat-lp and contact your emergency
medical centre right away if you experience any signs of pale skin, hives, rashes, edema (swelling),
mood changes, excessive fatigue, behaviour changes, irregular heartbeat, breathing difficulty,
breathlessness, swallowing difficulty and/or signs of any infection.
unknown side effects / symptoms: hepcinat-lp may cause other unknown side effects or
symptoms not listed here. For complete information, discuss the use of hepciant-lp with your
doctor or healthcare medical practitioner before use.
pregnancy / breast feeding - do not use hepcinat-lp if you are pregnant or breastfeeding or trying
to get pregnant.
unprotected sex - hepcinat-lp is contradicted for use during unprotected sexual intercourse as it
may also lead to birth defects.
antacids - hepcinat-lp is not to be taken within a before and after 4 hour period of taking any
antacids.
sofosbuvir / ledipasvir medications - do not take hepcinat-lp when taking other medications
having sofosbuvir and/or ledipasvir as their active ingredients. Hepcinat-lp is also contradicted
when taken alongside other medications used in the treatment of hepatitis c virus (hcv) infection.
sofosbuvir / ledipasvir allergy - hepcinat-lp is contradicted for use if you are allergic to sofosbuvir
and/or ledipasvir which are the active ingredients of hepcinat-lp.
other herbal / dietary supplements / prescription medicines / otc medicines - hepcinat-lp may be
contradicted for use when taken with other medications to treat tuberculosis, seizures, hiv,
cancer, cholesterol, heart ailments and other anti-viral medications. Consult your medical
practitioner or doctor before using hepcinat-lp by providing a list of any and all existing
medications that you are taking to ascertain the safety and use of hepcinat-lp.
hepatitis c is a viral infection that causes inflammation of the liver. Genotypes are used to identify
particular strains of hcv which are based upon differences in particular regions of the viral
genome. Harvoni (gilead sciences, inc.) Is a prescription medicine which contains a combination
of sofosbuvir and ledipasvir in the dosages form of 90mg and 400 mg that is used for treatment
of chronic hepatitis c (chc) genotype 1 infection in adults. It is not recognized yet if harvoni is safe
and effective medicine for children under 18 years of age.
Genotype 1 hcv is the most common infection accounting for 70 to 75% of the entirely hepatitis
c infections in the united states. Ledipasvir and sofosbuvir are antiviral medications that help to
prevent hepatitis c virus (hcv) cells from multiplying in your body.
The indian generic of harvoni to be manufactured by Abbott pharma limited is available now in
india under the trade name hepcinat-lp. This drug also have similar effects as harvoni in treating
chronic hepatitis c (chc) genotype 1 infection in adults. The recommended dosage of hepcinat-lp
is one tablet taken orally once daily with or without food.
8 weeks:this treatment can be considered for naive patients without cirrhosis who have pre-
treatment hcv rna < 6 million iu/ml
12 weeks:for experienced patients without cirrhosis those have failed treatment with either
peginterferon alfa + ribavirin or an hcv protease inhibitor + peginterferon alfa + ribavirin.
24 weeks:for experienced patients with cirrhosis who have failed treatment with either
peginterferon alfa + ribavirin or an hcv protease inhibitor + peginterferon alfa + ribavirin
harvoni (ledipasvir 90mg & sofosbuvir 400mg) - ledipasvir inhibits ns5a, an important
phosphoprotein, which is involved in viral replication, assembly and secretion. Resistance
selection in cell culture and cross-resistance studies indicates ledipasvir aims ns5a as its mode of
action.
Sofosbuvir is an inhibitor of the hcv ns5b - the key enzyme mediating hcv rna replication. Virus
needs rna molecule to reproduce, and sofosbuvir prevents this rna molecule from forming.
Ledipasvir & sofosbuvir work synergetically to weaken hepatitis c replication. In such a way, virus
is weakened. Immune system does the rest.
the most common adverse reactions were fatigue and headache in subjects treated with 8, 12,
or 24 weeks of harvoni. Other possible adverse reactions could be nausea, diarrhoea and
insomnia.
Note: the patient should not take any antacid 4 hours prior or 4 hours after taking the drug. The
patient should be more careful in case the antacids contain magnesium or aluminium. If there is
any allergic reaction or any sign of reaction to harvoni like difficulty in breathing or swelling of
the tongue, lips, face or throat; it is recommended to consult the specialist concerned
immediately. Please tell your healthcare provider or contact your treating doctor directly if you
found any side effect that bothers you or that does not go away.
hepcinat-lp comes in the category of prescription drugs that is also categorized in the list of
prescription medicines but in order to dispense this particular drug, there is a legal requirement
of a medical prescription. The drug can be made available in all the major cities of india. The
confirmation of the order of this particular drug will be made after the valid prescription from
hepatologist or hcv treatment specialist.
Our commitment: our objectives is to help people suffering from hepatitis c and other serious
life threatening diseases across the world in procuring indian medicines which are trusted by
doctors, medical practitioners and other institutions all around the world and are available at
cheap and competitive prices.
lifesaverpharmalike to assure you of the best of the quality of medicines and services in the
industry. Hepcinat-lp, the generic version of harvoni, is now available in india at affordable price.
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