Professional Documents
Culture Documents
TheJOURNAL
of PEDIATRICS
November 2017 Volume 190 Copyright 2017 by Elsevier Inc.
Notes from the Association of Medical School Pediatric Department Chairs, Inc.
Work Equity and Investment-based Pediatric Departmental Reorganization
ScottA.Rivkees, MD ......................................................................................................................................................... 6
Editorials
Threading the Needle for the Tiniest Babies
BreeAndrews, MD, MPH, and LainieFriedmanRoss, MD, PhD . ............................................................................................ 8
Newborn Screening for Spinal Muscular Atrophy and Lysosomal Storage Disorders Takes Advantage
of Novel Therapies
HansC.Andersson, MD .................................................................................................................................................... 9
Medical Progress
Subclinical Atherosclerosis in Youth: Relation to Obesity, Insulin Resistance, and Polycystic
Ovary Syndrome
BrendaMendizbal, MD, MS, and ElaineM.Urbina, MD, MS . ............................................................................................... 14
The Journal of Pediatrics (ISSN 0022-3476) is published monthly by Elsevier Inc., 230 Park Avenue, Suite 800, New York, NY 10169-0901, USA. Periodicals
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Original Articles
The Relationship between Coronary Artery Disease Risk Factors and Carotid Intima-Media
Thickness in Children
DanWhite, BS, RebeccaPlace, MS, TimothyMichael, PhD, EricHoffman, PhD, PaulM.Gordon, PhD, and PaulVisich, PhD ......... 38
50 Years Ago in The Journal of Pediatrics Diagnosis of Cerebrospinal Fluid Rhinorrhea: Lack of
Specificity of the Glucose Oxidase Test Tape
SusyJeng, MD . ............................................................................................................................................................ 48
Alkaline Phosphatase in Infant Cardiopulmonary Bypass: Kinetics and Relationship to Organ Injury
and Major Cardiovascular Events e
JesseA.Davidson, MD, MPH, TracyT.Urban, BS, ChristineBaird, BS, SuhongTong, MS, AlanWoodruff, MD, MarkTwite, MD,
JamesJaggers, MD, EricA.F.Simes, MB, BS, DCH, MD, and PaulWischmeyer, MD ................................................................. 49
Body Composition in Children with Chronic Illness: Accuracy of Bedside Assessment Techniques
EnidE.Martinez, MD, CraigD.Smallwood, RRT, NicolleL.Quinn, RD, LDN, KatelynAriagno, RD, LoriJ.Bechard, PhD, RD,
Christopher P.Duggan, MD, MPH, and NileshM.Mehta, MD ................................................................................................ 56
Assessing Childrens Report of Stool Consistency: Agreement Between the Pediatric Rome III
Questionnaire and the Bristol Stool Scale
ManaH.Vriesman, MD, CarlosA.Velasco-Benitez, MD, CarmenR.Ramirez, MD, MarcA.Benninga, MD, PhD,
CarloDi Lorenzo, MD, and MiguelSaps, MD ....................................................................................................................... 69
Physical Therapy for Fecal Incontinence in Children with Pelvic Floor Dyssynergia
SwathiMuddasani, MBBS, AmandaMoe, PT, DPT, CaitlinSemmelrock, PT, DPT, CaroylLuanGilbert, PNP,
ValentineEnemuo, MD, EricHowardChiou, MD, and BrunoPedroChumpitazi, MD, MPH . ..................................................... 74
50 Years Ago in The Journal of Pediatrics Prenatal Treatment of Cretinism: Preliminary Studies
of Its Value in Postnatal Development
Raye-AnndeRegnier, MD .............................................................................................................................................. 78
Pancreatic Enzyme Replacement Therapy in Children with Severe Acute Malnutrition: A Randomized
Controlled Trial e
RosalieH.Bartels, MD, ClineBourdon, MSc, IsabelPotani, MSc, BrianMhango, MSc, DeborahA.van den Brink, BSc,
JohnS.Mponda, MSc, AnnekeC.Muller Kobold, PhD, RobertH.Bandsma, MD, PhD, MichaelBoele van Hensbroek, MD, PhD,
and WiegerP.Voskuijl, MD, PhD ........................................................................................................................................ 85
Time Trends in Food Allergy Diagnoses, Epinephrine Orders, and Epinephrine Administrations in
New York City Schools
ElizabethFeuille, MD, CherylLawrence, MD, CarolineVolel, MD, MPH, ScottH.Sicherer, MD, and JulieWang, MD . .................. 93
50 Years Ago in The Journal of Pediatrics Cholestyramine Therapy in Patients with a Paucity of
Intrahepatic Bile Ducts
KaitlinGiblerWhaley, MD ............................................................................................................................................ 107
Early Caffeine Prophylaxis and Risk of Failure of Initial Continuous Positive Airway Pressure in Very
Low Birth Weight Infants e
RaviM.Patel, MD, MSc, KaneciaZimmerman, MD, MPH, DavidP.Carlton, MD, ReeseClark, MD, DanielK.Benjamin, PhD, and
P.BrianSmith, MD, MHS, MPH ......................................................................................................................................... 108
Early Mortality and Morbidity in Infants with Birth Weight of 500Grams or Less in Japan e
HirosukeInoue, MD, PhD, MasayukiOchiai, MD, PhD, KazuakiYasuoka, MD, KoichiTanaka, MD, HiroakiKurata, MD,
JunkoFujiyoshi, MD, YukiMatsushita, MD, PhD, ShutaroSuga, MD, KazuakiNonaka, DDS, PhD, TomoakiTaguchi, MD, PhD,
KiyokoKato, MD, PhD, and ShouichiOhga, MD, PhD, on behalf of theNeonatal Research Network of Japan (NRNJ) .................... 112
Newborn Screening for Lysosomal Storage Disorders in Illinois: The Initial 15-Month Experience
BarbaraK.Burton, MD, JoelCharrow, MD, GeorgeE.Hoganson, MD, DarrellWaggoner, MD, BradTinkle, MD,
StephenR.Braddock, MD, MichaelSchneider, MD, PhD, DorothyK.Grange, MD, ClaudiaNash, MS, HeatherShryock,
RebeccaBarnett, BA, RongShao, PhD, KhajaBasheeruddin, PhD, and GeorgeDizikes, PhD . ...................................................... 130
What Happens to Blood Glucose Concentrations After Oral Treatment for Neonatal Hypoglycemia?
DeborahL.Harris, PhD, GregD.Gamble, MSc, PhilipJ.Weston, MBChB, and JaneE.Harding, DPhil . ....................................... 136
Trial of Music, Sucrose, and Combination Therapy for Pain Relief during Heel Prick
Procedures in Neonates e
SwapnilR.Shah, FRACP, ShahajahanKadage, MBBS, and JohnSinn, FRACP . .......................................................................... 153
Shifting Risks and Conflicting OutcomesECMO for Neonates with Congenital Diaphragmatic
Hernia in the Modern Era e
JosephW.Turek, MD, PhD, JosephR.Nellis, MBA, BrentonG.Sherwood, BS, MeeraKotagal, MD, MPH, FACS,
AndrewL.Mesher, MD, RaviR.Thiagarajan, MBBS, MPH, SonaliS.Patel, MD, PhD, JeffreyR.Avansino, MD, FACS,
PeterT.Rycus, MPH, D.MichaelMcMullan, MD, FACS, and ThomasV.Brogan, MD ................................................................ 163
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Increased DNA Methylation of ABCB1, CYP2D6, and OPRM1 Genes in Newborn Infants of
Methadone-Maintained Opioid-Dependent Mothers e
PoppyMcLaughlin, PhD, HelenMactier, MBChB, MD, FRCPCH, CherylGillis, MBChB, TamasHickish, MA, MD, FRCP,
AntonParker, BSc, Wei-JunLiang, PhD, and M.DavidOsselton, PhD, FRCS . ........................................................................... 180
Modes of Infant Feeding and the Risk of Childhood Asthma: A Prospective Birth Cohort Study e
AnnikaKlopp, MD, LorenaVehling, MSc, AllanB.Becker, MD, PadmajaSubbarao, MD, PiushkumarJ.Mandhane, MD,
StuartE.Turvey, MBBS, DPhil, DianaL.Lefebvre, PhD, MalcolmR.Sears, MD, the CHILD Study Investigators
MeghanB.Azad, PhD . ...................................................................................................................................................... 192
The Child Opportunity Index and Disparities in Pediatric Asthma Hospitalizations Across One Ohio
Metropolitan Area, 2011-2013 e
AndrewF.Beck, MD, MPH, BinHuang, PhD, KathrynWheeler, NikkiR.Lawson, BS, RobertS.Kahn, MD, MPH, and
CarleyL.Riley, MD, MPP, MHS .......................................................................................................................................... 200
Case Not Closed: Prescription Errors 12 Years after Computerized Physician Order Entry
Implementation e
GiliKadmon, MD, MichalPinchover, BSc(Pharm), AvichaiWeissbach, MD, ShirleyKogan Hazan, RN, and
ElhananNahum, MD ........................................................................................................................................................ 236
Language Growth in English Monolingual and Spanish-English Bilingual Children from 2.5 to
5 Years e
ErikaHoff, PhD, and KrystalM.Ribot, PhD ......................................................................................................................... 241
Timing and Chronicity of Maternal Depression Symptoms and Childrens Verbal Abilities
MarilynN.Ahun, BA, Marie-ClaudeGeoffroy, PhD, CatherineM.Herba, PhD, MaraBrendgen, PhD, JeanR.Sguin, PhD,
Anne-LaureSutter-Dallay, MD, MichelBoivin, PhD, RichardE.Tremblay, PhD, and SylvanaM.Ct, PhD .................................. 251
Delayed Presentation and Prolonged Survival of a Child with Surfactant Protein B Deficiency e
JuanA.Lpez-Andreu, PhD, AntonioD.Hidalgo-Santos, MD, MiguelA.Fuentes-Castell, MD, NuriaMancheo-Franch, MD,
JuanA.Cern-Prez, MD, MariaJ.Esteban-Rics, MD, LaiaPedrola-Vidal, PhD, and LawrenceM.Nogee, MD . ........................... 268
Prenatal Risk Factors for PHACE Syndrome: A Study Using the PHACE Syndrome International
Clinical Registry and Genetic Repository
JoyWan, MD, JackSteiner, BS, EulaliaBaselga, MD, FrancineBlei, MD, MariaCordisco, MD, MariaC.Garzon, MD,
DeborahS.Goddard, MD, AnitaHaggstrom, MD, AlfonsKrol, MD, IlonaJ.Frieden, MD, DeniseMetry, MD,
KimberlyD.Morel, MD, JudithM.A.Verhagen, MD, OrliWargon, MD, BethA.Drolet, MD, and DawnH.Siegel, MD . ................. 275
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Reply
DerekB.Hoyme, MD, and DianneL.Atkins, MD . ................................................................................................................ 292
Reader Services
Information for Readers ............................................................................................................................................ A8