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Definition
• Meningitis (inflammation of the membranes that cover the brain and spinal cord)
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• Encephalitis (inflammation of the brain)
• Guillain-Barré syndrome (inflammation of the nerves outside the brain and spinal
cord)
• Multiple sclerosis (disease caused by inflammation, destruction, and scarring of
the sheath that covers nerve fibers in the brain and spinal cord)
• Any disorder affecting the nervous system
• Central nervous system syphilis
• Lymphoma, leukemia, or other cancers involving the brain or central nervous
system
• Certain forms of hydrocephalus (water on the brain)
• Bleeding in the brain or spinal cord
Prior to Procedure
Anesthesia
• Local anesthesia
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Description of the Procedure
• You lie on your side with knees drawn up to abdomen. A needle is inserted into
the spinal canal through your lower back. A sample of CSF is withdrawn through
the needle. The pressure of the CSF is measured. If you experience discomfort,
the needle may need to be repositioned. If you have a problem with your lower
back and cannot lie on your side, the CSF may be taken from the top of the spine.
After Procedure
• The fluid is sent to a lab for analysis. You lie down for 10-15 minutes. Unless you
have a severe headache, you can leave.
• 30 minutes or more
Will It Hurt?
• Overall, discomfort is minimal to moderate. The anesthetic will sting when first
injected. There is usually a little pain when the needle is first inserted, but it
should subside in a few seconds.
Possible Complications
• Local bleeding
• Headache
• Backache
• Allergic reaction to the anesthetic
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• Herniation and death
• Local infection
• Pain or abnormal burning, pricking, or tingling sensations in your legs
• Hematomas (blood clots)
• Inflammation of the arachnoids mater (a delicate membrane lining the nervous
system)
• Temporary paralysis of a cranial nerve
• Rupture of the soft, central portion of the intervertebral disk (called the nucleus
pulposus)
• Tumor (called intraspinal epidermoid tumor)
• Meningitis
Postoperative Care
Based on the pressure and contents of the CSF, a diagnosis can often be made. High
pressure can indicate swelling, bleeding, a tumor, or hydrocephalus.
• Antibodies
• Bacteria, viruses, fungi
• Cancer cells
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• Excess protein
• White blood cells
Normal CSF is clear and contains no blood. If there is blood or a yellowish color, it may
indicate an obstruction or bleeding in the brain or spinal cord.
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REFERENCES:
• http://www.aafp.org/
• http://www.nlm.nih.gov/
• http://www.aboutkidshealth.ca/
• http://www.hc-sc.gc.ca/index_e.html