Professional Documents
Culture Documents
Delivery
Encapsulation
Systems
Eric Perrier
to surround an active ingredient with a molecule, a membrane or
a network made of a polymer, or of a specific organization of simple
molecules
Frost and Sullivan
in order to protect and deliver active cosmetic ingredients in
todays increasingly complex products
Kline and Company
initially developed to enhance active stabilization; however,
increased penetration of the active into the skin has become a very
important aspect of their use
Product Purpose
Arden (Cellulite hand Glitter capsules for visual effect
lotion)
Avon (Skin-so-Soft Mineral oil capsule
hand lotion
Biopredict Increased alcohol content in wine
Colgate palmolive Fragrance
(Soft soap body wash)
Dr. Scholls foot Sponge technology for delivery of
powder fungicide
Extract (Acne Sponge technology for benzoyl
treatment) peroxide
Gillette (Degree Heat activated, antipersiprant
underarm product release
Gillette razor Lubrication, dimethicone capsules
Triplex toothpaste Encapsulated calcium peroxide
Consumers
expectations
Performance
improvement by
microencapsulation
Formulators
expectations
Make actives bio-available; control where to release
Skin vs sweat gland, pH 5 vs pH7 environment
Penetrate barriers
Transdermal delivery
Concentrate payload
Enhance visual appearance
Capture and
release
mechanisms
Microencapsulation
Based on the combination of a payload
of active and encapsulating polymer,
brought together mechanically
Spray drying
Spray coating
Extrusion techniques
Spray drying of the active payload when blended
with natural gums
Mechanical Controlled
rupture release
Solubility of shell
It will readily material
dissolve when suspended in warm
aqueous medium
Melting of theupon
Depending shell the
material
melting point of the coating
material
Internal rupture
Involves of the shell
volatilization material
of the internal phase
Biological
Involves degradation of theofshell
the consumption the material
capsule wall by
microbial action
Molecular Type of
weight of polymer shell
polymer shell employed
employed