Wrinkle

Wrinkles are the clinical manifestation of ‘cutaneous aging’ and factors associated with wrinkles could be
‘intrinsic’ and ‘extrinsic’. Photoageing is the superposition of chronicultraviolet (UV)-induced damage on
intrinsic ageing and accounts for most age-associated changes in skin appearance. [2] Manifestations of
photoaging include superficial and deep wrinkles, development of a leathery texture, skin roughness, atrophy
and dyspigmentation.

Elastosis
The most typical and common manifestations of solar elastosis are wrinkled, non-
elastic, thick, multicolored skins of yellow mixed with hypopigmented macules and
hyperpigmentation.

Talengiastaea
Telangiectasia is most commonly found in patients with sensitive skin (atopy), as
well as patients who are frequently exposed to excessive sunlight, to rosacea, or to
patients who frequently use excessive steroid cream. In some cases. Telangiectasia
looks like a thin red line on the skin, generally on the cheeks and nose.

Purpura
Purpura is a condition in which there is a change of color on the skin or mucous membranes due to
bleeding from small blood vessels. Petekie is a purpura with a diameter smaller than 2 mm.

Colloid milia
Colloid milium is limited to the skin and tends to be distributed on sun-exposed,
actinically damaged areas, particularly the cheeks, periorbital region, nose, ears,
neck, dorsal hands, and forearms.

The Process of Aging

As our bodies age, they naturally deteriorate. In the later years, many essential functions begin
operating at a suboptimal level. There are three main factors that influence the body's aging process.

First, as we grow older, the number of mistakes incurred by daily cellular reproduction increases. The
body actually creates nonfunctional cells, leading to more rapid deterioration of the body's functions.
With advancing age, a larger percentage of our cells, even though they're present, are useless. And
worse yet, these nonfunctional cells sometimes interfere with normal cellular processes.
The second part of the aging process relates to cellular damage that causes the shortening of DNA,
eventually triggering a process called apoptosis or "programmed cell death." This is particularly
important when we realize that there are DNA fragments in each of our cells' many mitochondria
compartments. When these mitochondria serve as energy generators during normal cell functions,
oxygen free radical by-products are produced, and damage can occur to healthy DNA, creating DNA
fragments and triggering cell apoptosis. As time passes, increased damage to healthy DNA leads to
accelerated cell death, and our old bodies simply cannot generate cells fast enough to compensate
for the loss. This process is most visible and obvious in our skin—the older we get, the thinner our
skin becomes.

The third part of the aging process involves the cellular down-regulation of our natural oxidative
enzymes such as superoxide dismutase and catalase and glutathione perxoidase, making our
antioxidant defenses less efficient with age.

Polifenol
Polyphenols are a group of chemicals found in plants. ... In some studies mentioned that the
polyphenolic group has a role as an antioxidant that is good for health.