Urogenital

 system  2
Dewajani Purnomosari
Department of Histology and
Cell Biology
Faculty of Medicine
Universitas Gadjah Mada
d.purnomosari@ugm.ac.id
 Urinary  tract  

The  calyces,  renal  pelvis,  ureter  and  

bladder  have  the  same  basic  
histology  structure  à  ge9ng  
thicker  closer  to  the  bladder.  
Urogenital  tract  layers  

The  mucosa  is  lined  by  

stra<fied  transi<onal  
epithelium  or  urothelium.    
Folded  lamina  propria,  
submucosa.  
 
The  muscular  layer  
consist  of  interwoven  
smooth  muscle  layer.  
 
The  adven00a.  
Three  layers  of  urothelium  

Single  layer  of  small  basal  

cells,  res<ng  on  the  very  
thin  basement  membrane  
 
Intermediate  region,  one  
to  several  layers  of  more  
columnar  cells  
 
Superficial  layer,  very  
large,  polyhedral  à  
umbrella  cells  
 
 Urinary  bladder  

Bladder  wall  close  to  urethra   Empty  bladder,  mucosa  is  highly  folded.  
Full  bladder,  mucosa  is  pulled,  urothelium  
thinner,  umbrella  cells  are  flaEer  
 Urethra  

Tube  that  carries  the  urine  from  the  bladder.  

Urethral  mucosa  has  large  longitudinal  folds.  
In  men,  two  ducts  for  sperm  join  the  urethra  
Schema<c  of  urethra  
Penis  
 Male  urethra  

Male  urethra  consist  of  3  segmens:  

The  prosta0c  urethra,  3-­‐4cm  long,  
extend  through  prostate  gland,  lines  
by  urothelium  
 
The  membranous  urethra,  short  
segment,  passes  through  external  
sphincter,  lined  by  stra<fied  and  
pseudostra<fied  columnar.  
 
The  spongy  urethra,  15  cm,  within  
erec<le  <ssue  of  penis,  lined  by  
stra<fied  and  pseudostra<fied  
columnar.  
 
Female  urethra  

Female  urethra  is  

exclusively  a  urinary  
organ  
 
A  tube  4  –  5  cm  
 
Lined  by  transi<onal,  
then  stra<fied  
squamous  epithelium.  
 
The  middle  part  is  
surrounded  by  the  
external  striated  
muscle  sphincter.  
THANK YOU