Biochemistry I (LSCI-211) Fall 2017

Instructors:
Dr. Reza Salavati (Course coordinator)
Email: Reza.salavati@mmcgill.ca
Building: Parasitology Building
Room: P-211
Phone Number: 514-398-7721
Office Hours: by email appointment
Dr. Armando Jardim
Email: Armando.Jardim@mcgill.ca
Building: Parasitology Building, Macdonald Campus
Room: P105
Phone Number: 514-398-7727
Office Hours: by email appointment
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Lectures: Monday and Wednesday 11:35 AM - 12:55 PM. (Raymond R2-045)
Course Readings: Lehninger Principles of Biochemistry by Nelson and Cox, W.H. Freeman Inc., N. Y.,
Sixth/Seventh edition available at bookstore and library on reserve
Alternatively, for the ebook, students are able to purchase via VitalSource with rental options from 60 days to a
lifetime purchase ranging from $63.83 USD - $114.23 USD.
https://www.vitalsource.com/products/lehninger-principles-of-biochemistry-david-l-nelson-v9781464187957
McGill MyCourses: Class slides and discussion board
Course pre/co-requisite: Organic Chemistry (FDSC 230)
Course Overview: Fundamental principles of biochemistry: Biochemistry of proteins, enzymes, nucleic
acids, lipids, and carbohydrates. Introduction to intermediary metabolism.
Communications: Announcements regarding class cancellations or dissemination of important information
will be performed by email.
Instructional Methods: Course content will be delivered largely presented through a lecture format which is
supported by tutorial sessions that will be organized by Teaching Assistants. These tutorials are not compulsory
and will have a “question and answer” structure aim at strengthening specific concept covered during the lectures
or through course material readings.
Marking System:
First Mid-Term Examination 25%
Second Mid-Term Examination 25%
Final Examination (lectures 1-24) 50% (refer to Faculty Examination Schedule)
The Mid-terms will consist of ~30 questions (multiple-choice and short answer)
The Final exam will consist of ~100 multiple-choice questions
Teaching Assistants:
Ms. Georgia Limniatis Email: Georgia.limniatis@mail.mcgill.ca
Office hours: Thursday 12pm-2pm
Phone number: 514-398-7957
Location: Parasitology Building Room P117 http://www.mcgill.ca/maps/?Building=000467
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Mr. Anand Vardhan Email: anand.atreya@mail.mcgill.ca
Office hours: Tuesday 10am-12pm
Phone number: 438-929-9734
Location: Parasitology Building Room P117 http://www.mcgill.ca/maps/?Building=000467
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Day Date Lecture Topic Chapter
Lehninger
W 9/6 1 Introduction; Water: properties, ionization (Dr. Reza 1, 2
Salavati)
M 9/11 2 molecular interactions 2

W 9/13 3 pH and buffer 2

M 9/18 4 Amino acids, peptides, and proteins structure 3-4

W 9/20 5 Proteins: purification 3

M 9/25 6 Classification of enzymatic reactions 6

W 9/27 7 Enzyme catalysis and mechanism 6

M 10/2 8 Enzyme Kinetics 6

W 10/4 9 Enzyme Kinetics and inhibition 6

M 10/9 Thanksgiving

W 10/11 10 Enzyme Kinetics and inhibition 6

M 10/16 Mid-term I Centennial Centre building Ballroom

11:35 AM - 12:55 PM
W 10/18 11 Nucleic Acids 8

M 10/23 12 Nucleic Acids

W 10/25 13 Lipids: structure, nomenclature and properties (Dr. A. 10

Jardim)
M 10/30 14 Membranes: bilayers, composition and structure, fluid 11
mosaic model Lipids
W 11/1 15 Carbohydrates: structure, nomenclature, and properties 7

M 11/6 16 Carbohydrates: structure, nomenclature, and properties

W 11/8 17 Carbohydrates: structure, nomenclature, and properties

M 11/13 18 Principles of bioenergetics 13

W 11/15 19 Principles of bioenergetics

M 11/20 Mid-term II Centennial Centre building Ballroom

11:35 AM - 12:55 PM
W 11/22 20 Intermediary Metabolism: Glycolysis 14, 15
 M 11/27 21 Intermediary Metabolism: Glycolysis

W 11/29 22 Intermediary Metabolism: Tricarboxylic Acid (TCA) Cycle 16

M 12/4 23 Electron transfer and oxidative phosphorylation 19

W 12/6 24 Electron transfer and oxidative phosphorylation (cont’d)

Final Exam covers Lectures 1-24

(refer to Faculty Examination Schedule)
“McGill University values academic integrity. Therefore, all students must understand the meaning and
consequences of cheating, plagiarism and other academic offences under the Code of Student Conduct and
Disciplinary Procedures (see www.mcgill.ca/integrity for more information).”
“L'université McGill attache une haute importance à l’honnêteté académique. Il incombe par conséquent à tous les
étudiants de comprendre ce que l'on entend par tricherie, plagiat et autres infractions académiques, ainsi que les
conséquences que peuvent avoir de telles actions, selon le Code de conduite de l'étudiant et des procédures
disciplinaires (pour de plus amples renseignements, veuillez consulter le site http://www.mcgill.ca/integrity ).
“In accord with McGill University’s Charter of Students’ Rights, students in this course have the right to submit
in English or in French any written work that is to be graded.”