Clustering used group of symptoms.
It is useful
approach and uses shape, color and texture based
approaches for classification purpose. The user can give
concept / keyword as text input or can input the image
itself from blood vessels.
 They are the first sign of diabetic retinopathy as in
fig.4 (a).
 Hemorrhages:
The blood leakage are identified by the retina .They
can appear anywhere in the retina, with any size and
shape.
 Exudates: accumulations of lipidic deposits
within the retina.
Fig.4.(a) Micro aneurysm Fig.4.(b) Exudate
I. Automatic screening system – A review
Fuzzy multiple criteria decision making are
combined with synthetic weight defined by human
preference. [12]Fuzzy c means are researchers based
algorithm. Compare to the other algorithm. The
fuzzy c means performs exact real valued estimates.
Fuzzy c means cluster operates on the iterative
searching to the set of the fuzzy clustering DR
images. [13] The pre-processing steps involved in
this approach are the data are pre-processed using
data cleaning. The commonly used Stop words is,
was, like, and, are, this, etc are removed. Stemming
words, Special characters, numbers, White spaces etc
are removed from Symptoms. The preprocessed
images are segmented using the Fuzzy C Means
when the required number of clusters is pre-
determined; thus, the algorithm tries to put each of
the data points to one of the clusters.
Step 1: Initialize Symptoms weight in vector
Step 2: Calculate the fuzzy membership.
Step 3: Calculate the centers for vectors
Step 4: Euclidean distance between ith data and
jth cluster center
Step 5: Create Cluster .it Gives best result for
overlapped data set.
They are the many clustering techniques are used,
main motive to improve the development by fuzzy c
means. Fuzzy c means are researchers based
algorithm. compare to the other algorithm. The fuzzy
c means performs exact real valued estimates. Fuzzy
c means cluster operates on the iterative searching to
the set of the fuzzy cluster. fuzzy c means are used to
associates cluster that represent the structure of the
data as best as possible. Fuzzy c means are capable
of detecting the approximate similar sized spherical
clusters. Fuzzy partitions the data X= {X1, X2, X3,
X4, X5---------Xn) in to the c fuzzy cluster by
minimizing the group by sum of the squared error
objective functions.
In the Image preprocessing image plays an
important role. The level of image are describes under the
color are describes in RGB and HSV color spaces. The
quality of an image range is in gray levels. The image
collection operations are used to extend the large digital
image. The image is used to visualize under efficient
way. The images are recasted under the dictionary
learning. The hybrid methods are represented in the
global and local features of image representation. The
keyword based image retrieval system matches user text
query to the textual description of the images and return
all the images whose description is the possible match.
Clustering based techniques are summarizing under the
sampling problem using Discrete Cosine Transform. In
machine learning, part techniques are a class of
calculations for example investigation, whose best known
part is the bolster vector machine (SVM). The general
errand of example examination is to discover and think
about general sorts of relations (for instance bunches,
rankings, chief segments, connections and orders) in
datasets. Calculations fit for working with bits
incorporate the portion perceptron, bolster vector
machines (SVM), In Adoptive Kernel Based SVM, the
input is given as x, y and the output is correctly classified
Cr, Incorrect Classified Ci. The values are initialized to
the variable I1=0 to In=0.
In STEP1, the required text article is chosen.
In STEP2, the Kernel points are classified by using the
input values and then the constant value is added in the
equation.
In STEP3 and STEP4 the resultant value of Kernel
point kp is compared with the Occurrence of words and if
kp resultant values is higher, then it is correctly classified.
Input: {(x1, y1).........(xn,yn)}
Output: correctly classified Cr, Incorrect Classified Ci,
Initialize: T1=0,.......Tn=0
Loop:
Step 1 : Choose and image dataset t,
Step 2: calculate the kernel and add constant for
reduce the problem.
Kp =((x1-x2) x^2)/2?+c
Step 3: Set Tp to be the solution of reduce the
problem.
Step 4: Kp>Occ is correctly classified.
Kp<Occ is incorrectly classified
Output: S(?) = {Cr,Ci}
II. Proposed Method for Classification of DR
In the proposed method, preprocessing step enhances
the quality of the image. Further to improve the
contrast between exudate and non-exudate regions,
shade correction is performed. The second stage
involves segmentation of exudates from the green
channel image after removal of blood vessels and
optic disc. The GLCM features are extracted from
the segmented region. Using the extracted feature
five classifiers SVM, SCG-BPN, GRN, PNN, and
RBF are trained and tested for obtaining the best
classifier.
2.1 Image Pre-processing
This step begins by collecting data from all the different
The green band is largely used for identification of sources. The collected data will have various data, all of
exudates, since it gives more information than red
and blue bands. The green channel image is filtered
by applying a morphological opening as structuring
element in order to remove vessel central light
reflex, since it may contribute to false detection of
exudates. Background homogenization is done using
arithmetic mean kernel which smoothens the
intensity values uniformly.
2.2 Exudate Detection
The exudates are segmented by removing blood
vessels and optic disc from the green channel image
extracted from the fundus image. The steps for
exudate detection are as follows.
Step1. Blood vessel segmentation
Blood vessels are prone to cause bright lesion like
appearance during the segmentation of exudates.
They are the many clustering techniques are used,
main motive to improve the development by fuzzy c
means. Fuzzy c means are researchers based
algorithm, compare to the other algorithm. The fuzzy
c means performs exact real valued estimates. Fuzzy
c means cluster operates on the iterative searching to
the set of the fuzzy cluster. Fuzzy c means are used
to associates cluster that represent the structure of
the data as best as possible. Fuzzy c means are
capable of detecting the approximate similar sized
spherical clusters.
𝐶 𝑚
𝐽𝑚 = ∑𝑁
𝑖=1 ∑𝑗=1 𝑢𝑖𝑗 ‖𝑥𝑖 − 𝑐𝑗 ‖
2
1≤ m ≤ ∞
Step2. Optical disc segmentation
The segmentation of optic disc is crucial since it is
circular in shape with high contrast and is similar to
exudates. The optic disc is removed using a circular
mask.
Step3. Exudate segmentation
which are not needed for a particular application. So, C (i,j) – is the (i,j) the entry in co-occurrence matrix
thecollected data is segmented and a data selection C
procedure is performed where the interested subsets of
data are extracted according to certain criteria ∑𝑖 means ∑𝑖=𝑀
𝑖=1 where M is the number of rows

Feature Extraction ∑𝑗 means ∑𝑗=𝑁

Generally in order to mine the huge amount of
data and certifiable information sets, the reflection of
raw information in any information mining
methodology is an approach to outline and fabricate
a model with a specific end goal to recover
significant data. The point of feature extraction is to
find the principle qualities of an information set
which are indistinguishably agents of the first
information
At times an excessive amount of data can lessen the
adequacy of information mining. A portion of the
segments of information traits amassed for building
and testing a model may not contribute important
data to the model. Some may really reduce the
quality and precision of the model. Insignificant
attributes just add noise to the information and
influence model exactness. Commotion expands the
span of the model and the time and framework assets
required for model building and scoring. Also,
information sets with numerous properties may
contain gatherings of characteristics that are
associated. These qualities may really be measuring
the same fundamental component. Their nearness
together in the assemble information can skew the
rationale of the calculation and influence the
exactness of the model.
𝑗=1 where N is the number of
columns
∑𝑖,𝑗 means ∑𝑖 , ∑𝑗
𝜇𝑖 is defined as 𝜇𝑖 = ∑𝑖 𝑖 ∑𝑗 𝑐(𝑖, 𝑗)
𝜇𝑗 is defined as 𝜇𝑗 = ∑𝑖 𝑗 ∑𝑗 𝑐(𝑖, 𝑗)
Dissimilarity [18] is a measure that defines the
variation of grey level pairs in an image. It is
computed as in (4)
Dissimilarity= ∑𝑖,𝑗 |𝑖 − 𝑗|𝑝(𝑖, 𝑗)
(4)
The performance comparison for the enhanced
mechanism gets compared with the existing mechanism
by calculating the entropy, precision, recall and Fmeasure
values of the extracted feature. The comparison of the
performance are get measured by using the true positive,
true negative, false positive and false negative values.
Precision is used to retrieve the objects which are
presented relevant to each other. They are computed
by,
Precision =Tp/(Fp + Tp)
Recall is used to compute the fraction of related
objects, which is computed by,

Recall =Tp/(Fn + Tp)

∑𝑖 ∑𝑗(𝑖,𝑗)𝑝(𝑖,𝑗)−𝜇𝑥 𝜇𝑦
Correlation = Accuracy =(Tp+Tn)/(Fp +Fn + Tp+ Tn)
𝜎𝑥 𝜎𝑦

𝑖,𝑗
Cluster shade =∑𝑖,𝑗 ((𝑖 − 𝜇𝑖 ) +
3
(𝑗 + 𝜇𝑗 )) 𝑐(𝑖, 𝑗) (3)
 III. Classification the clustering results with application of the trained SVM
Classification partitions information tests into target classifier.
classes. The arrangement procedure predicts the objective That will provide development of more exact SVM
class for every information focuses. For instance, patient classifier. In the second case we use part of the
can be named "high hazard" or "low" patient on the clustering results received by means of the fuzzy
premise of their infection design utilizing information clustering algorithms' ensemble for training of SVM
order approach. It is an administered learning approach classifier, and another - for the specification of the
having known as various categories of classes. Parallel clustering results by means of the trained SVM
and multilevel are the two techniques for arrangement. In classifier. We use in the SVM algorithm, which is
twofold order, just two conceivable classes, for example, usually applied to reduce the cost of graph splitting
"high" or "low" hazard patient might be considered while and receive better. the graph splitting into clusters.
the multiclass approach has more than two focuses for That will provide higher quality of objects'
instance, "high", "medium" and "low" hazard quiet. classification.
Information set is divided as preparing and testing
dataset. Rightness of the classifier could be tried utilizing 3.2 Back Propagation Neural Network
test dataset. Arrangement is a standout amongst the most The Neural Support Vector Machine (NSVM) is a
broadly utilized techniques of Data Mining in Healthcare hybrid learning algorithm. That consisting of neural
association. networks and support vector machines (SVMs). The
The exploration work uncovered that there is no single output of the NSVM is given by SVMs that take a central
best calculation which yields better result for each feature layer as their input. The feature-layer
dataset. Arrangement methods are moreover utilized for representation is the output of a number of neural
anticipating the treatment expense of human services networks that are trained to minimize the dual objectives
administrations which is expansions with fast of the SVMs. Because the NSVM uses a shared feature
development consistently and is turning into a primary layer, the learning architecture is able to handle multiple
concern toward everybody [5]. outputs and therefore it can also be used as a
dimensionality reduction method. The neural network
3.1 Support Vector Machine datasets show that the NSVM in general outperforms a
standard SVM and a multi-layer perception. Furthermore,
SVM is an exciting algorithm and the concepts are experiments on eye images show that the NSVM auto
relatively simple. written for developers with little or no encoder outperforms state-of-the-art dimensionality
background in statistics and linear algebra. The stay high- reduction methods. The parameters of neural classifiers
level in this description and focus on the specific are generally adjusted by gradient descent. By feeding the
implementation concerns. The combined implementation training samples a fixed number of sweeps, the training
of the SVM algorithm. And the fuzzy clustering time is linear with the number of samples. The training
algorithms. It is offered to use the fuzzy clustering time is generally proportional to the square of number of
algorithms' ensemble based on the clusters' tags' vectors' samples.
similarity matrixes and the spectral factorization
algorithm as for creation the training and test sets, used
for development of SVM classifier, as for specification of
3.3 Generalized Regression Network
The kernel is defined as K. kernel logistic regression
is estimate the probability in multi class case through
kernel multi-logic regression.SVM performs the
number of import points. The attribute values lead
the better tree result using very fast decision tree.
The probability can efficiency performs a test and
train process using the segment of data. Color pixels
does not require the full dataset read as part to
reducing time. The stream model converts leaf at the
bottom of the tree to split the node using
−𝐷𝑖 2
∑𝑛
𝑖=1 𝑌𝑖 exp( )
2𝜎2
Y(X) = _𝐷2
∑𝑛 𝑖
𝑖=1 exp(2𝜎2 )
The distance Di between the training sample and the
point prediction is used as a measure of each training
sample.
5.4Convolution
The convolution at a point is the product of two
function that occurs when the leading edge of the
moving pulse is at that point. The generalization
performance of neural classifiers is sensitive to the
size of structure, and the selection of an appropriate
structure relies on cross validation. The convergence
of neural network training suffers from local minima
of error surface. On the other hand, the QP learning
of SVMs guarantees finding the global optimum.
The performance of SVMs depends on the selection
of kernel type and kernel parameters, but this
dependence is less influential.
IV. Conclusion
The DR can be effective for the blindness to be
prevented.the SVM classification the often results
in a large numbers. which should be stored and
computed in the SVM classification. Neural
classifiers have much less parameters, the number of
parameters is easy to control. In a word, neural
classifiers consume less storage and computation
than SVMs.SVM to enhance the characterization
precision with the fitting element subset. The single
target wellness capacity was intended to assess the
element subset by presenting the v-fold cross-
acceptance preparing model exactness and the
quantity of the chose highlights. The results are also
sent to the physician’s e-mail which can be viewed
by him in his desktop or mobile phone. This work
mainly reduces the time consumption needed for the
diagnosis of mass screening processes.
References
1. Mariotti S. and Pascolini D: Visual Impairment,
Vision Loss and Blindness 2010 global estimates,
and VI and blindness causes. Global Data on Visual
Impairments 2010, WHO (2010)
2. Kande G. B., Subbaiah P. V., Savithri T. S.:
Feature extraction in digital fundus images. In:
Journal of Medical and Biological Engineering, vol.
29, No. 3, (2009).
3. Jonas, J., Schneider, U., and Naumann, G. (1992).
Count and density of human retinal photoreceptors.
Graefe’s Arch Clin Exp Ophthalmol, pages 230:505–
510.
4. Abramoff, M. D., Garvin, M. K., and Sonka, M.
(2010a). Retinal imaging and image analysis. IEEE
Reviews in Biomedical Engineering, 3:169–208.
Walsh, A. C., Wildey, R., Lara, C., Ouyang, Y., and
Sadda, S. R. (2010). Detection of fundus
abnormalities using 3d-oct versus mydriatic color
fundus imaging. In ARVO 2010.
5. Niemeijer, M., Garvin, M., van Ginneken, B.,
Sonka, M., and Abramoff, M. (2008). Vessel
segmentation in 3d spectral oct scans of the retina. In
Proceedings of SPIE, volume 6914.
6. P. Massin, A. Erginay, A. Gaudric, and E.
scientifiques et médicales Elsevier. Rétinopathie
diabétique. Ed. scientifiques et médicales Elsevier,
2000.
7. Alireza Osareh, Bita Shadgar, and Richard
Markham: A Computational Intelligence Based
Approach for Detection of Exudates in Diabetic
Retinopathy Images. IEEE Transactions on
Information Technology in Biomedicine, Vol. 13,
no. 4, pp. 535-545, (2009).
8. Doaa Youssef, Nahed Solouma, Amr El-dib,
Mai Mabrouk, and Abo-Bakr Youssef : New
Feature-Based Detection of Blood Vessels and
Exudates in Color Fundus Images . Image
Processing Theory Tools and Applications (IPTA),
2010 2nd International Conference on 7-10, pp. 294
– 299, (July 2010).