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Vol. 02 NO 9 February 27th, 2018.

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BASED 3D PRINTED HUMAN LIVER NORMAL REGENERATION OF BURNT SUPPORTING TALENTED PHD RESEARCH PAGES 11-12
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First Human-Sheep Hybrid Breakthrough Alert!


The quest to create animals with human
organs has a long history – and it is now
becoming a reality. In a remarkable feat,
Stanford scientists have now created the
first successful human-sheep hybrid.
The quest to create animals with human
organs has a long history – and it is now
becoming a reality. In a remarkable feat,
Stanford scientists have now created the
first successful human-sheep hybrid.
A biomedical advance that has long
been a dream and a quandary for scien-
tists hoping to address a critical shortage
of donor organs is now reality thanks to
a Stanford University study wherein sci-
entists have successfully grown embryos
inside a surrogate for three weeks which
had both sheep and human cells.
By Disha Padmanabha

STANFORD SCIENTISTS
DEVELOP FIRST
HUMAN-SHEEP HYBRID
The human-sheep chimera spells good news The embryos, which were not allowed to de-
for people suffering from type 1 diabetes, in velop past 28 days of age, move researchers a
addition to holding potential for mass-pro- small step closer to perhaps growing human
duction of human organs for transplants. organs for medical transplant.
Building on a controversial breakthrough The team say they have already been able to
made in 2017, the scientists this week, were use genome editing techniques to produce pig
able to grow a sheep embryo injected with and sheep embryos that are unable to develop
adult human stem cells for 28 days, including a pancreas, although they are still working on
21 days inside a sheep, it was announced at a the approach. And for such embryos to grow
meeting of the American Association for the and replace missing organs, Dr Hiro Nakau-
Advancement of Science in Austin, Texas. chi of Stanford University, who is part of the
The human portion of the embryos created in team, said a longer experiment, perhaps up to
the experiment is exceedingly small, but the 70 days, would be more convincing, although
fact it exists at all is what generates consid- that would require additional permission pancreas, from a sheep or pig, to a desper- and none of them are perfect, but they offer
erable controversy in this field of research. from institutional review boards. ate patient. For the transplant to work, the hope to people who are dying on a daily ba-
researchers think at least 1 percent of the em- sis,” he said. “We need to explore all pos-
“The contribution of human cells so far is “Even today the best matched organs, ex- bryo’s cells would need to be human – mean- sible alternatives to provide organs to ailing
very small. It’s nothing like a pig with a hu- cept if they come from identical twins, don’t ing these first steps demonstrated in the sheep people.”
man face or human brain,” stem cell biolo- last very long because with time the immune are still very preliminary.
gist Hiro Nakauchi told media at a presenta- system continuously is attacking them,” says
tion of the research this week in Austin, Texas, another lead of the team, reproductive biolo- As work continues, ethical scrutiny will
explaining that, by cell count, only about one gist Pablo Ross from the University of Cali- also surely intensify. Ross and his colleagues
in 10,000 cells (or less) in the sheep embryos fornia, Davis. acknowledge the controversial nature of their
are human. work, but they also say that they’re moving
Although it’s still a long way off, organs cautiously. Ross, for one, sees the ever-wid-
The experiment had to be terminated, as the produced in interspecies chimeras could be ening approaches for organ research as cause
law prohibits developing cross-species em- one way of producing enough supply to meet for optimism.
bryos, called chimera, for more than 28 days. demand – by transplanting, say, a hybridised
“All of these approaches are controversial,

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1
February 27th, 2018. Vol. 02 NO 9

Flipkart Founder Funds


Bangalore Based
3D Printed Human Liver
Tissue Startup
Bengaluru-based biotechnology startup The tissues, made of human cells, would
Pandorum Technologies has reportedly raised allow for inexpensive medical research with
$3.2 million in its series A funding from Bin- decreased reliance on animal and human tri-
ny Bansal, Indian Angel Network (IAN) and als, and could eventually be used for liver
other high net worth individuals (HNIs). transplants.
Founded in 2011 by Arun Chandru and Tu- The company believes their 3D bio-printed
hin Bhowmick, the startup works on tissue mini-livers that mimic the human liver will
engineering and regenerative medicine. serve as reliable test platforms for discovery
The startup has received Rs 7.9 crore ($1.2 and development of drugs with better effica-
million) of the Rs 21 crore and the remaining cy, less side effects and at lower costs.
capital will come in tranches. This flagship product was developed in
After successfully 3D printing human liv- 2015 and can be used in medical research for
er tissues which can be used for medical re- drug metabolism and disease modelling. The
search, the startup is currently bio-engineer- designed product can perform functions of a
ing human cornea for implants. The biotech human liver tissue including detoxification,
intends to use the funding to further scale up metabolism, and secretion of biochemicals
its operations, hire talent and deepen its re- such as albumin and cholesterol.
search and development. By Disha Padmanabha

Indian Scientist
SCIENTISTS DEVELOP $2 PER GENE
Successfully Controls DIY SEQUENCING TECH
Diabetes in Animal Study Improving our ability to construct and func- that they either limit the length of a gene to
India currently faces an uncertain future in he said while talking to Sakal Times. “We tionally characterize DNA sequences would about 200 base pairs- the sets of nucleotides
relation to the potential burden that diabetes have identified a molecule which can keep broadly accelerate progress in biology. But that made up DNA- or are prohibitively ex-
may impose upon the country. And with over the sugar levels in the permissible limits. We the speed breaker pops up in the form of ex- pensive for most labs.
62 million diabetic individuals currently di- have successfully conducted a few trials on penses- currently, gene sequences from com- The team’s new method involves isolating
agnosed with the disease, it is fast gaining the mice. For this diabetes trial, we had collab- mercial vendors cost approximately $50 to small sections of thousands of genes in tiny
status of a potential epidemic. The aetiology orated with Shantani Proteomics. We have $100 per gene. droplets of water suspended in an oil. Each
of diabetes in India is multifactorial and in- to collaborate with biologists for trials on Studies being pursued in a wide range of section of DNA is assigned a molecular “bar
cludes genetic factors coupled with environ- animals. The data so far collected from the subjects in medicine- from antibiotic re- code,” which identifies the longer gene to
mental influences such as obesity associated research is interesting and we are further de- sistance to cancer – require conducting which it belongs. The sections which initial-
with rising living standards, steady urban mi- veloping it.” “high-throughput” experiments, where scien- ly are present in only very small amounts,
gration, and lifestyle changes. tists screen hundreds or thousands of groups are then copied many times to increase their
In 2000, India (31.7 million) topped the “I am working in the area of total synthesis of cells simultaneously. Analyzing large number. Finally, small beads are used to sort
world with the highest number of people with of biologically active natural products and numbers of cells, each with slight differences the mixture of DNA fragments into the right
diabetes mellitus followed by China (20.8 medicinal chemistry using ‘silicon incorpo- in their DNA, for their ability to carry out a combinations to make longer genes, and the
million) with the United States (17.7 million) ration approach’. Macrocyclic natural com- behavior or survive a drug treatment can re- sections are combined. The result is a mix-
in second and third place respectively. These pounds and silicon incorporation in known veal the importance of particular genes, or ture of thousands of the desired genes, which
numbers are projected to to double globally drug scaffolds with an ultimate aim of dis- sections of genes, in those abilities. can be used in experiments.
from 171 million in 2000 to 366 million in covering drugs are the special interests.” And given the current climate, sequencing In order to test this out, the scientists used
2030 with a maximum increase in India. genes for such studies involve high cost. DropSynth to make thousands of bacteri-
While scientists within the country and out- A well-experienced intellect, Dr. Reddy, Therefore, UCLA scientists have now pio- al genes- each as long as 669 base pairs in
side alike are toiling away in their labs, an spearheaded the group which has now syn- neered a new technique that allows for cheap- length. Each gene encoded a different bacte-
NCL scientist, Dr. Srinivasa Reddy has now thesized over 25 natural products that retain er and easier sequencing strategies. rium’s version of the metabolic protein phos-
been able to produce exciting results in the their native biological function. A few recent The approach, DropSynth, enables scien- phopantetheine adenylyltransferase, or PPAT,
field of study. achievements of his include the identification tists in any typical biochemistry laboratory which bacteria need to survive. Given PPAT
Dr. Reddy and team have been successful of potential leads in an antibiotic compound to make their own gene sequences for only is critical to bacteria that cause everything
in synthesizing a molecule with the help of based on a hunanamycin natural product for about $2 per gene. from sinus infections to pneumonia and food
which they were able to control diabetes in treating food infections, an anti-diabetic mol- poisoning, it’s being studied as a potential an-
mouse models. ecule in collaboration with an industry part- “Our method gives any lab that wants the tibiotic target.
ner and anti-TB compound using a strategy power to build its own DNA sequences,” said The researchers created a mixture of
“The clinical trials have been successful,” called ‘repurposing of a drug scaffold’. Sriram Kosuri, a UCLA assistant professor the thousands of versions of PPAT with
of chemistry and biochemistry and senior au- DropSynth, and then added each gene to a
thor of the study. “This is the first time that, version of E. coli that lacked PPAT and tested
without a million dollars, an average lab can which ones allowed E. coli to survive. The
make 10,000 genes from scratch.” surviving cells could then be used to screen
potential antibiotics very quickly and at a low
“There’s an ongoing need to develop new cost.
gene synthesis techniques,” said Calin Ple- The team is still working on reducing
sa, a UCLA postdoctoral research fellow and DropSynth’s error rate. In the meantime,
co-first author of the paper. “The more DNA though, the scientists have made the instruc-
you can synthesize, the more hypotheses you tions publicly available on their website. All
can test.” of the chemical substances needed to repli-
cate the approach are commercially availa-
By Disha Padmanabha
Another drawback of the current methods ble.
for synthesizing genes, he says is that fact By Disha Padmanabha

2
Vol. 02 NO 9 February 27th, 2018.

Gut-on-a-Chip Wields
Promise for Future of
Personalized Medicine
The small intestine is the major site for intestinal differentiation and function, but it
digestion, drug and nutrient absorption, in- could not be used to study processes that re-
teraction with commensal microbiome, and lied on normal intestinal cells from individu-
development of mucosal immunity, as well al donors.
as a primary site for many diseases, such as
bacterial, viral and parasitic infections and “We are now able to leverage the organoid
inflammatory bowel disease. approach to isolate intestinal stem cells from
And majorly attributable to the lack of hu- human biopsies, but we break up the orga-
man-relevant responses, many animal mod- noids and culture the patient-specific cells
els unsuitable to study causal factors and within our Organ Chips where they sponta-
treatment strategies for human intestinal neously form intestinal villi oriented towards
infections and disorders, three-dimensional the channel lumen, and the epithelium in
(3D) human tissue surrogates, such as intesti- close apposition to human intestinal micro- By Disha Padmanabha
nal organoids (also known as enteroids) have vascular endothelium,” said Ingber, who is A series of confocal microscopy sections taken through the intestinal epithelial and vascular channels of the primary Small Intestine-on-a-Chip visualizes first the
emerged as promising alternatives. also the Judah Folkman Professor of Vas- surface of epithelial villi-like structures (in red) and nuclei (in blue) of small intestinal epithelial cells in the intestinal channel, and then cell-cell contacts (in green) of
intestinal endothelial cells in the adjacent vascular channel. Credit: Wyss Institute at Harvard University
Organoids faithfully recapitulate the cellu- cular Biology at Harvard Medical School
lar diversity of the intestinal epithelium and (HMS) and the Vascular Biology Program at of reactive oxygen species, double-stranded
are ideally suited for in situ visualization Boston Children’s Hospital, as well as Pro- DNA breaks, degradation of lipids in the “This finding helps explain why other
and continuous monitoring of epithelial de- fessor of Bioengineering at Harvard’s John cell membrane, and loss of microvilli struc- models of the human gut that don’t include
velopment and differentiation. But the catch A. Paulson School of Engineering and Ap- ture, as well as junction disruptions between endothelial cells generally fail to mimic the
is, these organoids form all of the cell types plied Sciences (SEAS). “This approach pre- neighbouring cells and of the mucous mem- gut’s response to radiation injury,” says Oren
present in human intestine, but they grow as sents a new stepping stone for the investiga- brane that protects the intestinal wall. Levy, Ph.D., M.B.A., co-author of the paper
cysts surrounded by thick extracellular matrix tion of normal and disease-related processes Interestingly, the endothelial cells in the and Staff Scientist at the Wyss Institute.
gels with their “apical” cell surface (which is in a highly personalized manner, including blood vessel channel had a stronger response
normally exposed to the content of the gut) the transport of nutrients, digestion, differ- to radiation than the epithelial cells in the in- “More studies are needed to confirm the
facing an enclosed lumen. This prevents the ent intestinal disorders, and intestinal inter- testinal channel in terms of ROS generation, link between endothelial and epithelial cell
study of dynamic processes involving the in- actions with commensal microbes as well as lipid degradation, and DNA fragmentation. responses, but we think that ROS generated
testinal barrier, including nutrient and drug pathogens.” Furthermore, the endothelial cells experi- by endothelial cell damage will prove to be
transport, as well as its interactions with the enced peak apoptosis levels about 24 hours the driving force behind epithelial cell dam-
microbiome. In the course of this study, researchers used after exposure, while epithelial cells were age, and this could serve as a target for fu-
Therefore, researchers at the Wyss Institute a microfluidic device composed of a clear, hardest hit at 48 hours, suggesting that the ture anti-radiation therapeutics.”
led by Founding Director, Donald Ingber, flexible polymer containing parallel micro- endothelium is more sensitive to radiation.
M.D., Ph.D., had previously engineered a mi- channels separated by a porous extracellu- When the scientists repeated the experiment “In the future, such efforts could allow us to
crofluidic “Organ-on-a-Chip” (Organ Chip) lar matrix membrane. One channel is coated on a chip that only contained epithelial cells, much better understand human-microbiome
culture device in which cells from a human with human intestinal epithelial cells and the they observed that the irradiated cells did not interactions, model malnutrition disorders
intestinal cell line originally isolated from other with human endothelial cells which have the typical response to radiation: their and inflammatory diseases of the gut, and
a tumor were cultured in one of two paral- mimic the blood vessel wall. microvilli were not blunted, their mucosal perform personalized drug testing,” said co-
lel running channels, separated by a porous This chip was then exposed the chip to a barrier was not disrupted, their cell barriers first author Alessio Tovaglieri, a Graduate
matrix-coated membrane from human blood radiation dose of 8 Gray, which is known remained functional, and they had lower Student at the Department of Health Science
vessel-derived endothelial cells in the adja- to cause gastrointestinal effects in humans. ROS generation. This surprising result sug- and Technology at ETH Zurich in Switzer-
cent channel. The team then observed increases in several gests that endothelial cells play a key role in land, who performs his thesis work on Ing-
Admittedly, the chip enabled new insights markers of cell damage in both the endothe- the gastrointestinal damage observed in radi- ber’s team.
into how flow and cyclic peristalsis affects lial and epithelial cells: cell death, generation ation injury.

fied compounds called advanced glycation to develop further to more severe disease and
FIRST OF ITS KIND, end-products (AGEs). The scientists further assess if treatments are working.
Genetic causes are thought to be responsible
BIOMARKER-BASED TEST TO for around a third of cases of ASD, while the However, some experts have warned that we

INDICATE AUTISM IN CHILDREN rest are believed to be caused by a combina-


tion of environmental factors, mutations, and
shouldn’t expect to see the Warwick team’s
blood test being used in the real world any
rare genetic variants. time soon. “There have been several attempts
Scientists have now made some major Reader of Experimental Systems Biology at
The study used machine learning techniques at developing biomarkers for autism, none
headway in the early diagnosis of autism. Re- the University of Warwick who said: “Our
to study the blood of both children with and of which have been particularly success-
searchers at the University of Warwick have discovery could lead to earlier diagnosis and
without ASD in order to distinguish chem- ful,” said Autistica’s Director of Science, Dr
developed new blood and urine tests that intervention.”
ical differences between the two groups. James Cusack. “This attempt is weakened by
could identify autism in children.
Researchers looked at blood and urine sam- a small sample size, possible overfitting of
Autism spectrum disorders (ASD) are de- “We hope the tests will also reveal new
ples from 38 children diagnosed with ASD, data and a lack of comparison groups.”
fined as developmental disorders mainly causative factors. With further testing we
compared to a healthy control group of 31
affecting social interactions and range of in- may reveal specific plasma and urinary pro-
children. All the subjects studied were aged “This study does not tell us how effective-
terests and causing a wide spectrum of oth- files or “fingerprints” of compounds with
between five and 12. ly this measure can differentiate between
er disabilities, such as speech disturbances, damaging modifications. This may help us
The Warwick team discovered there were autism and other neurodevelopmental or
repetitive and/or compulsive behaviors, hy- improve the diagnosis of ASD and point the
chemical differences between the two mental health conditions such as ADHD and
peractivity, anxiety, and difficulty to adapt to way to new causes of ASD.”
groups. Working with a further collaborator anxiety…The design of the study itself is suf-
new environments, with or without cognitive
at the University of Birmingham, the chang- ficiently robust as an exploratory experimen-
impairment. Genetic causes are thought to be responsi-
es in multiple compounds were combined to- tal study, but the results cannot be used to
Furthermore, the high heterogeneity of the ble for around a third of cases of ASD, while
gether using artificial intelligence algorithm propose a potential new diagnostic measure
clinical presentation makes diagnosis of ASD the rest are believed to be caused by a com-
techniques to develop a mathematical equa- at this stage.”
difficult and uncertain, particularly at the bination of environmental factors, mutations,
tion to distinguish between ASD and healthy
early stages of development. Therefore, the and rare genetic variants.
controls. The outcome was a diagnostic test Surely, this study and what it has achieved is
researchers of the study set out to discover The team found a link between ASD and
better than any method currently available. highly interesting but then the outcomes are
and develop robust biomarkers for diagnosis damage to proteins in blood plasma. They
The team believes their next step towards far-fetched. It is far too soon to say whether
and progression of severity of ASD expecting found the most reliable of the tests they de-
establishing this as a reliable study is to repeat such tests could ever have a role in clinical
to facilitate earlier diagnosis and intervention veloped was examining protein in blood
it further with a larger experimental group so practice given its various limitations; for the
which could also potentially reveal new caus- plasma, which found children with ASD
as to confirm the diagnostic performance and foreseeable future, the way ASD is diagnosed
ative factors. had higher levels of the oxidation marker
to assess if the test can identify ASD at very will remain unchanged.
The team was led by Dr Naila Rabbani, dityrosine (DT) and certain sugar-modi-
early stages, indicate how the ASD is likely By Disha Padmanabha

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February 27th, 2018. Vol. 02 NO 9

Scientists Dig Out Genetic break, strain H58, a strain known to be as-
sociated with multidrug resistance. When
researchers looked further, they found this
biotics. Sporadic cases of typhoid with these
levels of antimicrobial resistance have been
seen before, but this is the first time we’ve

Cause of Typhoid strain of H58 had gained an extra strand of


bacterial DNA – a plasmid – that encoded for
additional antibiotic resistance genes. The ty-
seen an ongoing outbreak – which is con-
cerning.”

Superbug
phoid possibly picked up the plasmid from Dr Elizabeth Klemm, co-first author from
E. coli. the Wellcome Sanger Institute, said: “Antibi-
otic resistance has been mounting in typhoid
Typhoid fever remains a significant pub- strain behind a current outbreak has acquired “This is the first time we have seen an out- for decades. This outbreak was caused by a
lic health threat in low- and middle-income a plasmid that renders it resistant to five break of extensively drug-resistant typhoid,” multidrug-resistant strain that had gone a
countries, with an estimated ~200,000 ty- classes of antibiotics, according to an analy- said Elizabeth Klemm, who co-led the anal- step further and acquired an extra piece of
phoid-associated deaths each year. Caused by sis from an international team of researchers. ysis work at the Sanger Institute. “This out- DNA encoding additional genes for antibiotic
Salmonella entericasubsp. enterica serovar A typhoid fever outbreak emerged in Pa- break was caused by a multidrug-resistant resistance. We therefore classified this strain
Typhi (S. Typhi), a human-restricted mono- kistan in November 2016, with a number strain that had gone a step further and ac- of typhoid as extensively drug-resistant. This
phyletic serovar of S. enterica. S. Typhi, it of cases, especially in Sindh Province, re- quired an extra piece of DNA encoding addi- is the first time we have seen an outbreak of
is transmitted from human to human by the sistant to ceftriaxone, a third-generation tional genes for antibiotic resistance.” extensively drug-resistant typhoid.”
fecal-oral route, often via contaminated wa- cephalosporin, and to the first-line drugs
ter. Vaccination, access to clean water, and chloramphenicol, ampicillin, and trimethop- Charlie Weller, head of vaccines at Britain’s Dr Charlie Weller, Wellcome’s Head of Vac-
improved sanitation are effective means to rim-sulfamethoxazole. The strains were also Wellcome Trust global health charity, said cines, said: “The treatment options for ty-
prevent typhoid. resistant to fluoroquinolones, which are used the findings were a clear warning that “treat- phoid are running out. It’s time we focus on
After antibiotics were first introduced to to treat multidrug resistant cases. ment options for typhoid are running out” prevention, in addition to treatment. Vaccines
treat typhoid in the 1940s, typhoid’s mortali- Now, a study by researchers at the Well- and focussing on prevention was now vital. offer another way to tackle drug resistant in-
ty rate plummeted from around 26 percent to come Sanger Institute shows the typhoid fections and we have a unique opportunity to
just 1 percent. But within 20 years the first strain causing the outbreak acquired an ad- Professor Gordon Dougan, a senior author address typhoid with a new Typhoid Conju-
cases of typhoid resistant to chlorampheni- ditional piece of DNA to become resistant to from the Wellcome Sanger Institute and Uni- gate Vaccine that has been recently prequali-
col—one of the three first-line treatments for multiple antibiotics, including a third-gener- versity of Cambridge Department of Medi- fied by the World Health Organisation.”
typhoid appeared signaling a battle between ation antibiotic. cine, said: “We have used genetic sequenc-
antibiotic and bacteria. In the spring of 2017, collaborators Pro- ing to uncover how this particular strain of
Typhoid strains resistant to all three first- fessor Rumina Hasan and Dr Sadia Shakoor typhoid became resistant to several key anti-
line treatments, which are known as multi- from the Aga Khan University in Pakistan
drug-resistant (MDR) typhoid strains were contacted the Wellcome Sanger Institute to
quick to follow those resistant to only one genetically analyse the outbreak. Sanger In-
antibiotic. And when doctors began using stitute scientists performed whole genome
second-line antibiotics (more modern but sequencing of typhoid samples from Pakistan
expensive versions) such as fluoroquinolo- to investigate the genetic cause behind its
nes, typhoid followed with resistance against high level of antibiotic resistance.
those drugs, too. In the course of their study, the team was
Now, the Salmonella enterica serovar Typhi able to discover the strain behind the out- By Disha Padmanabha

Virtual 3D Human Cancer


Tissues to Accelerate,
Enhance Research
Three researchers from the University of “It currently takes many months before re-
Newcastle and the Hunter Medical Research searchers are able to obtain tissue samples
Institute (HMRI) have now designed the from a physical biobank and carry out in-
world’s first online platform that houses 2D vestigations with it. Once a researcher has
and 3D microscopy datasets of valuable clin- performed their study, that sample typically
ical human cancer biopsy samples, revolu- cannot be reused. Each digital cancer sam-
tionising the way researchers access critical ple in The Virtual Biobank is made up of high
information needed to advance cancer treat- resolution microscopy images in both 2D and
ment. 3D, plus important clinical and molecular
Jamie Flynn, Antony Martin and William information that provides the foundation for
Palmer, in collaboration with the Hunter virtual research into cancer.
By Disha Padmanabha
Cancer Biobank, created a virtual database
that displays 3D image datasets alongside “We’ve taken a tiny sample from tumor bi- Jamie Flynn, Antony Martin and William Palmer, in collaboration with the Hunter Cancer Biobank, created a virtual database that displays 3D image datasets
alongside traditional 2D micrographs used
traditional 2D micrographs used by pathol- opsies stored at the Hunter Cancer Biobank
ogists and researchers. According to website and converted them into a virtual copy, en- few minutes. into virtual reality for education and gener-
information, each dataset is furnished with abling anyone around the world with an in- The Biobank, further, includes a “Tissue al awareness. Hopefully soon, anyone with
detailed, de-identified clinicopathological ternet connection to carry out research from Tracker” that automatically collects metadata a smartphone and Google Cardboard could
and technical metadata in order to provide their computers or easily request access to so that all new tissue samples can be cata- experience the internal environment of can-
context for further research. Physical samples the physical sample they need. loged and experiments easily replicated. cer tissue and bring about new insights,” Dr
associated with each dataset can also be ob- While still in its early stages, the online Palmer said.
tained from the source biobank, using provid- “This process ensures the physical sample platform holds promising future potential in
ed contact details. Importantly, the datasets remains intact, but a 3D, digital copy with areas of research, education and even virtual
have been made available to both researchers clinical and experimental information is kept reality.
and the general public to encourage greater online for future use. This is particularly
utilisation of clinical data. critical for rare cancers, which are hard to “The technology and tools that we’ve put
Currently, tumour samples can be obtained study due to a limited number of samples,” together make this data available to anyone
from physical biobanks to conduct investiga- Dr Flynn explained. in the world. People in the fields of engineer-
tions. But the process is riddled with obsta- ing or computer science can now easily ap-
cles, including lengthy ethics applications, In the course of their work, the researchers ply their knowledge to questions surrounding
long wait times and high costs. Once a sam- used a hand-built laser microscope, engi- cancer. Educators can also access the site
ple is obtained, it can only be used for a sin- neered to create these advanced 3D images. and use real-world examples to teach pathol-
gle experiment. This is acknowledged as less Instead of analyzing a thin slice of the sam- ogy to the next generation of cancer clini-
than satisfactory, especially in the case of rare ple, the CLARITY light-sheet produces clear, cians and researchers.
tumours, where samples are hard to source. detailed 3D images of the whole tissue at a The cell nuclei are pictured here in red and the background structures and
cellular level in a process that only takes a “We’d also like to convert the 3D data fibers are green in a 3D breast cancer biopsy (0.06 inches in diameter)
(Credit: University of Newcastle)

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Vol. 02 NO 9 February 27th, 2018.

Induced Pluripotent Stem ed mice the tumors reduced in size signifi-


cantly, while cancer cells were completely
eliminated in two mice, which went on to live
“This approach is particularly powerful
because it allows us to expose the immune
system to many different cancer-specific

Cells Hold Potential as


for over one year following the experiment. epitopes simultaneously,” Kooreman said.
The results were subsequently replicated us- “Once activated, the immune system is
ing skin cancer and lung cancer cell lines. on alert to target cancers as they develop

Cancer Vaccines:
In a second experiment, researchers inocu- throughout the body.”
lated mice with the iPSC vaccine and then in-
jected them with mesothelioma cells, a form The researchers next would like to study

Stanford Study
of lung cancer. Compared to mice that had whether the approach works in samples of
not been vaccinated, those that got a mix- human cancers and immune cells in a labora-
ture of stem cells and the immune booster tory setting. If successful, they envision a fu-
mounted a robust defense against the can- ture in which people could receive a vaccine
Nearly a century ago, researchers observed “When we immunized an animal with genet- cer. In mice whose immune responses were comprised of their own irradiated iPS cells as
that immunization with embryonic materials ically matching iPS cells, the immune system strongest and most narrowly focused on the a way to prevent the development of cancers
led to the rejection of transplanted tumors. could be primed to reject the development of tumors, lung cancers were least likely to take months or years later.
More recently, studies identified shared tran- tumors in the future. Pending replication in hold and grow.
scriptome profiles and antigens on various humans, our findings indicate these cells may A third experiment using skin cancer cells “Although much research remains to be
tumor cells and embryonic cells. This has one day serve as a true patient-specific can- demonstrated that an iPSC vaccine might done, the concept itself is pretty simple,” Wu
led to the hypothesis that embryonic stem cer vaccine.” be useful in preventing cancer recurrence or said. “We would take your blood, make iPS
cells (ESCs) could be used as immunization metastasis after an existing tumor has been cells and then inject the cells to prevent fu-
agents to promote an anti-tumor response. “These cells, as a component of our pro- surgically removed. ture cancers. I’m very excited about the fu-
And exploring this cancer-fighting strategy, posed vaccine, have strong immunogenic ture possibilities.”
scientists have now been able to successfully properties that provoke a systemwide, can-
immunise mice against breast, lung and skin cer-specific immune response,” said Koore-
cancers, raising hopes that a human cancer man, who is now a surgery resident in the
vax could be just around the corner. Netherlands. “We believe this approach has
Like cancer cells, iPS cells can propagate exciting clinical potential.”
indefinitely. They can be coaxed to assume
many different kinds of cells, making them In the course of their study, the team admin-
the perfect ingredient in regenerative medi- istered a group of mice the potential cancer
cine, and best of all, they can be generated vaccine – genetically matched, inactivated
from adult stem cells. iPSCs in combination with a generic im-
mune-stimulating agent known as an adju-
“We’ve learned that iPS cells are very sim- vant. After four weekly injections of the vac-
ilar on their surface to tumor cells,” said cine, the mice were implanted with mouse
Joseph Wu, MD, PhD, director of Stanford’s breast cancer cells.
Cardiovascular Institute and professor of In the control groups the cancer grew and
cardiovascular medicine and of radiology. developed, but in 70 percent of the vaccinat- By Disha Padmanabha

Flu Kill Pill Wipes off First Concussion-Detecting Blood Test


Viruses Within 24 Hours Approved by the FDA
Japanese pharmaceutical company, Shion- for pandemic planning, this could be an ad- The U.S. Food and Drug Administration has nologies that minimize health impacts to pa-
ogi & Co., has now claimed that its experi- vantage,” the head of co-developer Roche’s now approved a blood test that can quickly tients while still providing accurate and reli-
mental drug can rid flu suffers of their symp- pharma unit, Daniel O’Day, told Bloomberg. and reliably detect signs of a concussion. able results to inform appropriate evaluation
toms in as little as a day, but the sad part is the The Brain Trauma Indicator, marketed by and treatment is an FDA priority. Today’s ac-
drug will be no good to this year’s epidemic “You don’t have the potential resistance Banyan Biomarkers Inc., measures the levels tion supports the FDA’s Initiative to Reduce
because it won’t be available to the United that comes with not completing your course of two proteins — called UCH-L1 and GFAP Unnecessary Radiation Exposure from Med-
States until 2019. of therapy.” — whose elevated presence suggests a cer- ical Imaging—an effort to ensure that each
Baloxavir, the flu drug discovered by Osa- tain type of brain damage normally only visi- patient is getting the right imaging exam, at
ka, Japan-based Shionogi, received prelimi- According to Japanese newspaper The Asa- ble on a CT scan. Test results currently can be the right time, with the right radiation dose,”
nary approval in Japan last week. Japanese hi Shimbun, the drug, which targets both the available within three to four hours. said FDA Commissioner Scott Gottlieb, M.D.
and American flu patients who took part in A and B types of influenza virus, received Concussion-related brain damage has be- “A blood-testing option for the evaluation of
the recent clinical trial of the Shionogi & Co. a green light from a Japanese government come a particularly worrisome public health mTBI/concussion not only provides health-
pill are said to have had the virus wiped out health ministry panel in early February, indi- issue in many sports, especially football, af- care professionals with a new tool, but also
from their bodies in about 24 hours through cating a likely go-ahead for imminent manu- fecting the ranks of professional athletes on sets the stage for a more modernized stand-
a single dose. facture and sale of the drug. down to the young children in Pop Warner ard of care for testing of suspected cases.
The experimental drug worked three times leagues. Those concerns have escalated so far In addition, availability of a blood test for
faster than another antiviral drug, Tamiflu, that it has led to a decline in children partici- mTBI/concussion will likely reduce the CT
the company told the The Wall Street Journal. pating in tackle sports. scans performed on patients with concussion
Tamiflu, which generated more than $3 bil- Patients with a positive test would need a each year, potentially saving our health care
lion in sales when swine flu sparked a global CT scan to confirm the results and determine system the cost of often unnecessary neuro-
contagion in 2009, reduces the duration of if surgery or other treatment is needed. The imaging tests.”
illness by only up to a day if it’s taken within test will first be used in emergency rooms,
the first 48 hours of the onset of symptoms. possibly as soon as later this year, but Ban-
What’s more, some seasonal strains have de- yan’s hope is that it will eventually be used
veloped mutations that decrease its potency, on battlefields and football fields.
spurring calls for alternatives. FDA Commissioner Dr. Scott Gottlieb said
the test fits with the agency’s goals for deliv-
While the overall time to alleviation of ering new technologies to patients and reduc-
symptoms was similar whether participants ing unnecessary radiation exposure.
took baloxavir marboxil or oseltamivir(sold In a large prospective study of 1947 individ-
under the brand name Tamiflu), Shionogi ual blood samples from adults suspected of
says its experimental drug provides immedi- having mTBI/concussion, the Brain Trauma
ate relief faster, which might curb the virus’s Indicator was able to predict the presence of
contagiousness in people who take the treat- intracranial lesions on CT 97.5% of the time
ment. and the absence of intracranial lesions on CT
99.6% of the time.
“The advantage is that it’s one pill once,
versus a course of therapy, so particularly By Disha Padmanabha “Helping to deliver innovative testing tech- By Disha Padmanabha

5
February 27th, 2018. Vol. 02 NO 9

Biodegradable Bandages level – vital and multi-purposed for every el-


ement in the healing process – stimulates the
regeneration of tissues.
philic properties, a polymer layer containing
carboxyl groups was applied to the surface.
The resulting layer was enriched with anti-

Expedite Normal
Attributable to the difficulty and pain as- bacterial and protein components”, noted
sociated, the bandages, are advised not to be Elizabeth Permyakova, one of the project
removed or changed during treatment- after members and laboratory scientists.

Regeneration of Burnt
a certain period of time, the biodegradable
fiber will simply dissolve without any side The research team has already conducted
effects. a series of pre-clinical trials jointly with the

Tissue
Research Institute of Experimental and Clini-
“With the help of chemical bonds, we were cal Medicine (Novosibirsk, Russia).
able to create a stable layer containing blood
Russian scientists have now constructed bi- was sought by designing biodegradable fib- plasma components (growth factors, fibrin- In vitro results have shown that with the
odegradable bandages using nanofibers made ers and multifunctional bioactive nanofilms, ogens, and other important proteins that application of these innovative bandages the
of polycaprolactone modified with a thin- which in turn help the bandages prevent scar- promote cell growth) on a polycaprolactone regeneration process has been accelerated
film antibacterial composition and plasma ring and accelerate tissue regeneration. base. The base fibers were synthesized by twice as quickly. In the near future, the team
components of human blood. The NUST MI- A significant acceleration of the healing electroforming. Then, with the help of plasma expects to get results of in vivo drug testing.
SIS University claim the bandages accelerate process, the successful regeneration of nor- treatment, to increase the material`s hydro-
the growth of tissue cells twice as quickly, mal skin covering tissue, and the prevention
contributing to the normal regeneration of of scarring on the site of burnt or damaged
damaged tissues, as well as preventing the skin have been observed when applying these
formation of scars in cases of severe burns. bandages made of the developed material to
Scar tissue mainly consists of irreversible an injured area.
collagen and significantly differs from the The antibacterial components of multifunc-
tissue it replaces, having reduced functional tional nanofibers decrease inflammation, and
properties. Therefore, as a solution to this the blood plasma with an increased platelet By Disha Padmanabha

SCHOLARSHIPS
Application Process: disorders
• genetics and genomics
Your full application package as a single • gene and protein engineering
collated PDF should consist of the following: • reproductive biotechnology
• transgenic technology
Your latest CV • bioinformatics
• human-animal interface and One
A research proposal with detailed plans and Health
timelines of the project, developed in close
collaboration with your proposed host. The Applications are invited for NIAB’s RSP
length should not be more than 4-5 pages in- 2018-2019 from highly motivated individ-
cluding references. uals who have secured national fellowships
PDF versions of 1 to 3 first-author publi- and who are willing to take up research work
cations. to meet the challenges in the above-men-
Campus Fellows Program Research Scholars tioned areas. Those admitted as Research
@ NCBS | Consolidated In addition, we require the following: – Program @ NIAB – NIAB’s Scholars could be registered for PhD through
a recognized University or through Region-
Salary of Rs. 90,000 p.m. • A letter of support from your proposed
RSP 2018-2019 al Centre of Biotechnology, Faridabad, after
host (emailed directly to acadoffice@ completion of course work and any addition-
ncbs.res.in) al requirements.
Purpose: • At least 2 letters of references (emailed Candidates with a Master’s degree in any
directly by the referees to acadoffice@ branch of Life Science (M.Sc., M.Tech., Eligibility and Selection Criteria:
The Campus Fellows Program is targeted at ncbs.res.in) M.V.Sc., or M.Pharm) are eligible to apply
postdoctoral scientists of exceptional talent, online for a Research Scholars Program Individuals desirous of seeking admission
and provides them broad independence and Deadlines: that is available at NIAB – National Insti- must have a Master’s degree in any branch
support to carry out their research in a host tute of Animal Biotechnology as Per the of Life Science (M.Sc., M.Tech., M.V.Sc.,
laboratory at NCBS or inStem. Fellows are There are two calls each year. This is the details posted below. or M.Pharm). Candidates must also have
expected to drive new research directions in first call in 2018, full applications must be re- secured CSIR/UGC/DBT/ICMR/INSPIRE
their host laboratories, and to establish them- ceived by the Academic Office (acadoffice@ Advertisement No. RSP-1/2018 NET JRF/UGC-RGNF or any other national
selves as independent scientists. ncbs.res.in) by 31st March 2018. Short-listed Admission for Research Scholars Program research fellowship for 5 years. Applications
candidates will have to present their research will also be accepted from candidates who
What’s Included? proposal and will be interviewed by the pan- National Institute of Animal Biotechnology have secured a fellowship and have com-
el in the last week of April 2018. Decisions (NIAB) invites applications for its Research pleted or are likely to complete the required
Campus Fellows are appointed for a period will be announced within 2 weeks of the in- Scholars Program 2018-2019. courses in the academic year 2018-19.
not to exceed 4 years, contingent on success- terviews.
ful annual review every year. The Fellowship NIAB is an autonomous and premier in- Fellowship :
provides a consolidated salary of Rs. 90,000 The next call will be in August, 2018. stitute of the Department of Biotechnology
per month as well as campus housing. The (DBT),Government of India. The Institute Having a fellowship is mandatory for con-
program is flexible: Fellows may choose to Contact Us: wishes to develop and harness novel and sideration. The terms and conditions, fel-
hold a part of their Fellowship off-campus emergingbiotechnological tools and applica- lowship amount etc. will be governed by the
for collaborative work and training relevant Please write to acadoffice@ncbs.res.in tions, and take up research in cutting-edge ar- awarding funding agency subject to the Rules
to their program of research. During their for any queries related to this program. eas forimproving animal health and produc- and conventions of the Institute.
tenure, Fellows are also eligible to apply for tivity as well as contribute to human health
external competitive awards. and welfare. Application and Selection Procedure:

Eligibility: NIAB’s current research interests include Candidates who meet the above eligibility
criteria may apply online (link at www.niab.
Candidates should not have more than 4 • host-pathogen interactions and pathog- org.in). The online application facility will
years of postdoctoral research experience. enomics
Fellows must be sponsored by a local host • next generation vaccines, diagnostics,
who is a member of NCBS/inStem Faculty. adjuvants and drug delivery platforms
• nutrition, metabolomics and metabolic Next Page>>>>

6
Vol. 02 NO 9 February 27th, 2018.

be open from 19/02/2018 to 05/03/2018. No Am I eligible? changes in barley leaf protective mech-
need to send the print out of applications. anisms under elevated CO2 concentra-
Applicants having difficulty in accessing the The STARS program is open to all appli- tion and higher temperature
portal may contact “The Senior Manager, cants who hold a master‘s degree or equiv- • Sexual selection and sexual trait evolu-
National Institute of Animal Biotechnology alent in sciences, medicine, pharmacology tion in Larix and Arabidopsis spp
(NIAB) at 040-2304-9403 or admin@niab. and a related field of study. It is also open • Microbial methane oxidation beneath
org.in. Applications found to be in order will to students who are in the last year of their the Greenland ice sheet
be screened, and only short-listed candidates studies and will be able to present their de- • The role of matrix metalloproteinases
will be called for interview to be conducted gree diploma at the beginning of their PhD and vimentin cooperation in cancer cell
on 26/03/2018. study. The candidate should be proficient in invadopodia function
Candidates must make their own arrange- English; however, no formal English exam • Link between chronic inflammation
ments for any travel, boarding and lodging. (such as TOEFL) is required. and bone homeostasis failure. The role
No TA/DA will be paid by NIAB for attend- Apply For PhD Under of extracellular nucleic acids and epi-
ing the interview. How can I apply? genetic mechanisms
The results will be announced within a STARS – Supporting • The social perception of sexual dimor-
week of the interview. Selected candidates Talented PhD Research You can choose up to three projects (see phism in human face
are expected to join the RSP by 15/04/2018. Open calls) for which you can then apply • Dynamics and persistence of avian
Those who have secured a fellowship and
Students @ through an online application form. blood parasite infection
have completed or are likely to complete Charles University, Prague • Evolution of brain complexity and pro-
the required courses in the current academic Find more about PhD project topics: cessing capacity in reptiles and birds: A
year, will be admitted provisionally pending If you hold a Master’s degree or equiva- (https://www.biotecnika.org/2018/02/ quantitative approach to understanding
satisfactory fulfilment of the requirements at lent in sciences, then you are eligible to ap- s t a r s - s u p p o r t i n g - t a l e n t e d - p h d - re - the tetrapod brain evolution
the time of joining. Reservations are as per ply for the STARS – Supporting TAlented search-students-charles-university/)
statutory norms. Single room hostel facilities PhD Research Students which is available How are candidates selected?
will be provided. at the Faculty of Science, Charles Univer- • Comparison of immunomodulatory
NIAB reserves the right to accept / reject sity in Prague, as Per the details posted properties of Mesenchymal stem cells The program is competitive. The super-
applications or candidature or admission below. and Sertoli cells visors of the individual PhD projects will
in case of any discrepancy observed at any • Opioid and metabolic modulation of shortlist eligible applicants, who will then be
stage. STARS – Supporting TAlented PhD Re- microglial function invited for an interview to be held during the
search Students Call for applications – PhD • Deciphering molecular mechanisms month of March. The exact interview dates
Important Dates: projects that govern cell expansion in Arabi- will be agreed between the supervisors and
dopsis root the candidates. Based on the interviews, the
Online application facility will be open What is STARS? • Cytosolic Iron-Suphur protein assem- applicants to whom the scholarship will be
from 19/02/2018 to 05/03/2018. bly pathway in the amitochondriate cell offered will be selected in the beginning of
STARS is a program supporting talent- • Mitochondrion of retortamonads April. The program starts on October 1st.
ed PhD students at the Faculty of Science, • Mechanisms of host immunomodula-
Charles University in Prague. The aim of this tion by Trichobilharzia regenti: focus Please do not hesitate to ask our coordina-
program is to provide excellent education and on parasite glycans and other immuno- tors if you have any questions!
an adequate income to PhD students of the logically relevant molecules
Faculty. The STARS program wants to attract • Effect of peripheral immune response Timetable:
the best students from the Czech Republic on neuroinflammation and learning
as well as from abroad. Faculty of Science, • in cognitively advanced birds • January 15, 2018 - PhD research topics
Charles University in Prague, is a top-quali- • The role of the Jak/STAT signalling and application form will be available.
ty centre of research in natural sciences. The cascade in the astrocyte clockwork of • March 16, 2018 - Deadline for appli-
Faculty takes care about its future and that’s the rat suprachiasmatic nucleus cation
why the STARS program was born. Come to • Dynamic structural and histochemical • October 1, 2018 - Start of the program
Prague and become the future of our Faculty!

7
February 27th, 2018. Vol. 02 NO 9

PhD ADMISSIONS

Integrated MS-PhD
PhD Programme
Biology Program
Admissions – August 2018
Admissions – August 2018
@ IISER Tirupati
@ IISER Mohali

If you are from a Bachelor’s Degree If you are looking for admission notifica-
background and are looking for integrated tions, and you are looking for appropriate
MS-PhD options, then IISER Mohali has Biology and Chemistry programs, then
requested interested and eligible candi- IISER Tirupati, has advertised for PhD
dates to apply online for their Biology pro- Program admissions, as Per the details
gramme that has been advertised accord- posted below. December 2015 or later) or INSPIRE-Ph.D. level tests) to shortlist candidates for inter-
ing to the details posted below. fellowship views.
IISER Tirupati invites applications from (OR)
Applications are invited from prospective prospective candidates for admission to the c. IISER BS-MS (All IISERs) Dual degree Fellowship:
candidates for admission to the Integrated Ph.D. programme, August 2018. IISER Tiru- students having CGPA >= 7.0.
MS-PhD Program at IISER Mohali in the ar- pati admits students in the disciplines of Bi- Upon selection and subsequently joining
eas of Biology, Chemistry, Mathematics and ology, Chemistry, Earth & Climate Science, • The fellowships/scores/ranks must be the Ph.D program, candidates who do not
Physics for the session beginning in August Mathematics, and Physics and associated in- valid at least till August 2018. Please possess any CSIR, DBT and INSPIRE, will
2018. terdisciplinary areas of research. In addition note that the admission criteria can be eligible for institute fellowship at par with
The programme involves course work as to research, the programme involves course- change during the next round of admis- CSIR, DBT etc., but without HRA compo-
well as research work. Successful completion work and teaching assistantship. sion. nent.
of the program will lead to an MS degree and Students with a master’s degree in Science / • SC/ST, PD and KM candidates Per-
a PhD degree. Mathematics are encouraged to apply to PhD centage may be relaxed with 5% or 0.5 Please Note: All communication with can-
programme. in case of CGPA. didates will be by email only.
Eligibility Criteria : Please note that the precise eligibility cri- • Candidates in the final year of their Kindly check this website for periodic up-
teria for August 2018 admissions may vary qualifying degree are also eligible to dates.In case of any application-related spe-
The applicant should have a Bachelors de- from department to department and are given apply. However, their final selection cific queries, please contact the respective
gree in Science and related areas with a good below. Information about individual faculty is subject to their successful comple- departments with your application number
academic record (at least 60% aggregate or at profiles and areas of research can be obtained tion of the qualifying degree with the mentioned in the subject at the following
least CGPI 6.0 on a scale of 10). from the IISER Tirupati website. above-mentioned requirements at the email addresses:
time of admission. A provisional de-
Additional Qualifications: The broad areas of research in each de- gree certificate is mandatory at the time • biophdselection@iisertirupati.ac.in,
partment include the following: of admission (Scheduled to be 1st Au- • chemphdselection@iisertirupati.ac.in
Applicants who have obtained one of the gust 2018). • physphdselection@iisertirupati.ac.in
following national-level qualifying examina- Biology: • mathphdselection@iisertirupati.ac.in
tions, are advised to mention the same in their Application Procedure: • earthphdselection@iisertirupati.ac.in
application form: Biophysics, Neuroscience, Plant biology,
Ecology and evolution, Cancer biology & Only online applications will be accepted. Applicants age should not exceed more than
1. Rank in JEST examination for Physics Immunology, Chemical Biology, Nano-Bi- Applicants can submit their forms for the re- 28 years at the time of joining. However, the
2. NBHM Masters or PhD scholarship for otechnology, Proteomics and Infectious dis- spective departments in the following links: relaxation in age will be considered as per the
Mathematics ease. Govt. of India regulations.
3. DST INSPIRE fellowship or KVPY Biology(https://form.jotform.
scholarship Chemistry: me/80450758069463) Important Dates:
4. Rank in IIT JAM for the chosen special-
ization Bio-Organic Chemistry, Nano-technology, Chemistry(https://form.jotform. • Opening date of Online Application :
Organic & Bio Molecular Chemistry, Inor- me/80450667869470) February 17, 2018
Application Procedure : ganic & Materials Chemistry, Theoretical, • Closing date of Online Application :
Analytical & Physical Chemistry The candidates must carefully fill and sub- April 30, 2018
Prospective candidates should apply online mit the online application form on or before • Interview Dates (Tentative) : June 7,
using the “Online Application Facility” by Eligibility Criteria For Various Depart- April 30, 2018. Applications will be screened, 2018 to June 14, 2018
visiting the website at http://www.iisermo- ments and shortlisted candidates will be intimated • Application Deadline – on or before
hali.ac.in Short-listed candidates will be in- (PLEASE CHECK THE TABLE ON further through emails only. Candidates be- April 30, 2018.
vited for a screening-test/ interview at IISER TOP OF THE PAGE) longing to reserved category will have to sub-
Mohali. mit relevant certificates, if selected.
General Information to the Applicants:
Last date : The online application facility Selection Procedure:
will be open till 12.00 noon, April 11, 2018. The candidate MUST have:
The shortlisted candidates will be called for
For further details about the program a. Qualified at least ONE of the above men- interview and final selection is based on in-
and research areas, please visit our web- tioned additional eligibility criteria terview performance.
site: http://www.iisermohali.ac.in (OR) The respective departments may use ad-
b. A valid CSIR/UGC-JRF or CSIR/UGC ditional criteria (based on academic perfor-
NET-LS (Date of examination should be mance and/or performance in the national

8
Vol. 02 NO 9 February 27th, 2018.

• The candidate MUST have qualified at pearing at Screening written rest and Selec-
least ONE of the above mentioned Ad- tion Interview for admission. The Part-Time
ditional eligibility criteria. Ph. D. programme candidate(s) have to con-
• The scores/ranks must be valid at least tinue to discharge their assigned duties along
till August, 2018. Please note that the with their research work as per the schedule
admission criteria can change during of the Ph. D. programme at the institute.
the next round of admission. While doing Ph.D course work HoDs will re-
• SC/ST, PD and KM candidates Per- schedule their assign duty.
centage may be relaxed with 5% or 0.5
in case of CGPA. (A) NIT Patna Employees (Faculty and
• Candidates in the final year of their Staff) may be admitted to Ph. D. programme
qualifying degree are also eligible to as a Part- time Internal candidate, provided.
apply. However, their final selection
Integrated PhD (i-PhD) is subject to their successful comple- PhD Admissions in Biotech a) The employees of the Institute have com-
tion of the qualifying degree with the pleted two years of regular service and are
Programme Admissions above-mentioned requirements at the
/ Biochem / also confirmed in his/her service at this in-
in Biological Sciences @ time of admission. A provisional de- Life Science – 2018 stitute.
IISER Tirupati gree certificate is mandatory at the time @ NIT Patna b) Employees who have been recruited
of admission (Scheduled to be 1st Au- against open advertisement on pay scale of
gust 2018). the institute are only eligible. The employ-
If you are looking for admission notifica- National Institute of Technology Patna ees appointed and paid by the project fund or
tions, and you are looking for appropriate Application Procedure: invites application for admission to Ph. D from any other temporary grant will not be
Biology and Chemistry programs, then Programme in Biotech / Biochem / Com- treated as internal candidate under the cate-
IISER Tirupati, has advertised for Inte- Only online applications will be accepted. putational Biology, Life Science for Se- gory of employee of the institute.
grated PhD Program admissions, as Per Applicants can submit their forms for the lection through Institute Admission Test c) The minimum eligibility of Degree and
the details posted below. respective departments using the following and Interview during Even emester (Jan- GATE/ NET requirement is mandatory for
links: Jun’2018) for the Session 2017-18 in the teaching /non-teaching employee(s) of NIT
The integrated Ph.D. (i-Ph.D.) programme following departments as detailed below. Patna having served less than 2 years at NIT
at IISER Tirupati is aimed for highly motivat- Biology(https://form.jotform. Patna.
ed students who wish to pursue a career in re- me/80450337769463) Chemistry Department : Chemistry, Ap- Those who have completed two years of
search. Students with an excellent academic plied Chemistry, Material Science & Tech- regular service and are confirmed in the ser-
record can apply for the i-Ph.D. programme Chemistry(https://form.jotform. nology, Bio-Chemistry, Environmental Sci- vices are exempted from GATE/ NET pro-
upon completion of a bachelor’s degree in me/80452263269458) ence, Analytical Chemistry, Bio-Technology, vided they fulfill the minimum eligibility
any branch of science. The course combines Nano Science & Technology, Chemical Sci- criteria.
curricula for master’s and doctorate degrees The candidates must carefully fill and sub- ence & Technology, Chemical Engineering,
into a single integrated programme with a mit the online application form on or before Polymer Science & Technology. Pharmaceu- (B) NIT Patna Faculty Appointed on
blend of course work and research projects. April 15, 2018. Only short-listed candidates tical Science, Computational Biology, Life Consolidated salary: and presently working
IISER Tirupati offers modern research lab- will be intimated further about the date of Science. Molecular & Biotechnology. in the Institute may be considered for admis-
oratories and computational facilities as well interview. Candidates belonging to reserved sion to the Doctoral program. Provided the
as hostel facilities for students. Students will category will have to submit relevant certifi- Categories: candidate
also have the opportunity to participate in a cates, if selected.
broad range of seminars, meetings and work- Candidates with following qualifications a) Fulfills minimum eligibility of qualifica-
shops, giving them a chance to interact with Selection Procedure: shall be eligible for admission to the Full- tion and GATE/ NET requirement for admis-
people from other research organizations Time Ph.D. Programme of the Institute. sion. and will be governed by the regulation
within the country and abroad. The shortlisted candidates will be called for Part-time Programme is only applicable for of the Doctoral program.
interview and final selection is based on in- the internal Candidates who are working as b) Having completed at least ONE year of
Overview of the i-Ph.D. programme: terview performance. The respective depart- a regular/contractual employee at NIT Patna. service in the institute and likely to contin-
ments may use additional criteria (based on The applicants seeking admission to the ue on the post in the Institute for at least one
IISER Tirupati offers Integrated Ph.D. academic performance and/or performance in Ph.D. Programme shall be classified under year in continuation, may be considered on
(i-Ph.D.) as a research programme with a the national level tests) in order to shortlist any one of the following categories. the recommendation of the HoD(s) of the de-
blend of course work (2 years) and research candidates for interviews. Fellowship: Finan- panment.
projects. On successful completion of the cial assistance will be provided by the insti- (i) Full Time Ph.D Programme: c) In case of continuing on the post and
doctoral research project, students are award- tute to the selected candidates. Please Note: drawing salary (as applicable). will not be el-
ed a degree in Master of Science and a Ph.D. All communication with candidates will be a) With Scholarship – Funded by NIT Patna igible for Institute Scholarship.
degree. The first four semesters consist of through emails only. Kindly check this web- b) With direct financial support from Govt. d) After termination of the contract, No
core courses, elective courses and advanced site for periodic updates. / Semi Govt. agencies such as CSIR, UGC, Institute Scholarship will be admissible and
courses specializing in one subject, and com- DST, DAE, etc. candidate will continue as self-Sponsored
bined with research work. On successful In case of any application-related queries c) Full time Sponsored employee of PSU, candidate. and continue to be governed by
completion of course work, related project which are not mentioned in the FAQs, please Government department, Research/Devel- the regulation of the Doctoral program.
work and a comprehensive exam, the student contact the respective departments with your opment organization, Private Industry of re-
continues with the research leading to a Ph.D. application number mentioned in the subject pute, Educational institutions Faculty/officer (C) JRF/ SRF under externally funded
The i-Ph.D. program is to be offered from at the following email addresses: as per our Ph.D regulation and sponsored Projects: – appointed and presently working
August 2018 in the Biological, Chemical, defence personnel with a minimum relevant in the Institute may be considered for admis-
Mathematical and Physical Sciences. experience of 2 years may be considered for sion to the Doctoral program, provided the
admission as a sponsored full-time research candidate
scholar.
d) Sponsored applicant will be eligible for a) Fulfills minimum eligibility of qualifica-
admission, if they are treated by their em- tion requirement for admission, and will be
ployers as on-deputation with their salary governed by the regulation of the Doctoral
and allowances and are relieved from their program.
organization/ institute for a minimum period b) Having completed at least ONE YEAR
of two years. as JRF/ SRF in the Institute and likely to con-
Eligibility Criteria: • bioiphdselection@iisertirupati.ac.in e) The sponsored candidates are exempt- tinue due to his/ her satisfactory performance
• chemiphdselection@iisertirupati.ac.in ed from GATE/ NET qualification, but they and research work.
1. Students with minimum 60% marks in should possess the minimum entry qualifi- c) The Principal lnvestigator(s) (Pl) of
aggregate (overall percentage with all sub- Important Dates: cation fixed by the institute as per eligibility the Project may recommend for admission
jects) or CGPA 6 out of 10-point scale in criteria for full time candidate selection. (based on his work performance and research
B.Sc./B.Tech/B.E. or any equivalent degree. • Opening date of Online Application : work), after approval of it by the DRC.
2. In addition to the above, students must February 17, 2018 (ii) Part Time: without Scholarship – In- d) The JRF/ SRF is likely to continue un-
have qualified any of the national level ex- • Closing date of Online Application : ternal Candidate admitted shall be consid- der the project. He/ she will continue to draw
ams listed in the following table for the re- April 15, 2018 ered against supernumerary seats. and shall salary as applicable and are not eligible for
spective departments. • Interview Dates (Tentative) : June 1, not be counted against open seats notified for
2018 to June 6, 2018 admission to the program. Candidates recom-
General Information to the Applicants: • Application Deadline – on or before mended by competent authority under •
April 15, 2018 Part-time category are exempted from ap-
Next Page>>>>

9
February 27th, 2018. Vol. 02 NO 9

e. No. Objection certificate from parent em- the South Asian Association for Regional
ployer (if applicable). Co-operation (SAARC) viz., Afghanistan,
Bangladesh, Bhutan, India, Maldives, Nepal,
(ii) The candidates are required to bring fol- Pakistan and Sri Lanka. The University, es-
lowing documents at the time of admission: tablished with the aim of evolving a South
Asian consciousness, offers Master’s and
a. Passport size Photographs ( 4 Nos.). PhD level programmes in Economics, Com-
b. Two set of Self attested copies of al I the puter Science, Biotechnology, Applied Math-
documents I isted above. ematics, Sociology, International Relations
c. Admission letter if an) issued b) the Insti- and Legal Studies.
tute verified document/ Admit Card used for SAU attracts students from all member na-
Admission Test. tions and its degrees are recognized by all the
eight SAARC countries.
Application Procedure: The University currently functions from
its Akbar Bhawan campus in Chanakyapu-
Note: Those who have applied against ear- ri, New Delhi. It will eventually move to its
lier Admission Notice No. 344/Acad./17-18 100-acre campus in Maidan Garhi, South
dated 16th October’ 2017. need not to apply Delhi, which is expected to be ready by the
again. Their candidature will be considered year 2019.
Institute Scholarship. appearing screening written test for admis-
in this round based on the application sub-
e) After termination of contract, Institute sion in Ph. D Program:
mitted by them previously. However. they Admission to PhD programmes:
Scholarship will not be admissible and can-
have to participate in the selection process
didate will continue as self-Sponsored candi- i) Having qualified National Level Ex-
a fresh. The following is a list of PhD programmes
date, and shall continue to be governed b) the amination/ Scholarship such as GATE/ IN-
offered at SAU. The figures in brackets show
regulation of the Doctoral program. SPIRE/ UGC­NET/ CSIR-NET or any other
1. All candidates are advised to apply only the number of seats available in each pro-
at National Level Fellowship/ Scholarship.
through online on NIT Patna website http:// gramme.
Eligibility Criteria For Selection For the ii) Teaching/ non-teaching employees.
www.nitp.ac.in. Application fees need to be Details about the faculty, admission pro-
Full-Time Candidate: Contractual teaching faculty and JRF/SRF
paid online through Institute website only. cedure and the format of Entrance Tests can
of externally funded research project of the
2. After submission of online application, be accessed by clicking on appropriate links
Candidates with following qualification Institute.
applicant should dov. nload the printed ap- below:
will be eligible for admission to the Ph. D. iii) Candidates with Master’s Degree from
plication and send it along with the required
Programme of the Institute. IIT(s), NIT(s) and IIIT(s) with minimum 8.5
documents, proof of on line pa):ment to the Faculty of Life Sciences & Biotechnology
M. Sc./ M. Com./ MBA/ MA or equivalent CGPA and fulfilling all other requirements as
address given below on or before 3rd April’ (http://www.sau.int/academics/faculties/
degree in relevant and related discipline with stated in the admission notice.
2018 by speed/registered post. Application faculty-of-life-sciences-biotechnology.html)
at least 6.0 CGPA (in the scale of 10) or 55
by hand will not be entertained.
percent marks or equivalent in aggregate A merit list is prepared after written test and
3. Application fee is of Rs. 1500/- for Gen- Eligibility Criteria, Admission Procedure
from a recognized institute or university. interview and admission is strictly based on
eral/ OBC/ Sponsored category and Rs. 750/- & Details of Entrance Test
Candidates with M. Sc./ M. Com./ MBA/ merit subject to verification of documents &
for SC/ ST/ PwD. (http://www.sau.int/admissions/admis-
MA or equivalent degree from IITs/ NITs/ original certificates.
4. Applicants from SC/ ST/ PwD category sion-notice-2018/52-admissions/2018-ses-
CFTI/ SFTI or Central/ State University in
must enclose Certificate issued by competent sion/618-phd-biotechnology-entrance-2018.
relevant discipline are required to produce a Scholarship & Financial Assistance for
authority to claim relaxation in application html)
proof of having qualified GATE/ JAM/ JEST/ Ph. D. Programme:
Fee.
CAT/ NET/ SLET/ JRF or equivalent nation-
• Applicants who have not completed
al eligibility test while taking admission in Institute Research Fellowship will be avail-
Postal Address for applications submis- their Master’s level course and are yet
the master degree in the relevant discipline able to the eligible students as per MHRD,
sion: to appear for their last year/semester
OR has valid Score in one of the national el- GOI norms. The period and amount of re-
exam may also take the Entrance Test.
igibility test. search fellowship shall be as per notification
Assistant Registrar (Academic) However, their admission will be sub-
B. Tech/ 8.E./ 8. Arch or equivalent degree of the competent authority from time to time.
National Institute of Technology Patna ject to their fulfilling the minimum eli-
in relevant discipline with at least 8.5 CGPA
Ashok Rajpath, PATNA-800005 (India) gibility criteria of aggregate percentage
(in the scale of 10) or 80 percent marks in ag- Note: The scholarships from any other
Phone: Office: (0612) 237-1929. 237-0843, of marks at the Master’s level besides
gregate fom a recognized technical institute agency/ organization are governed by rules
Ext. 247,263, 108; Fax: (0612) 2670631 clearing the Entrance Test. Please note
or university. with a valid GATE/ NET/ JAM/ and regulation of funding agency only, and
Institute Web Site: www.nitp.ac.in Email that such candidates will not have any
JEST qualifying score is mandatory. students shall be governed by their rules only.
ID: admission@nitp.ac.in claim to admission if their results are
a. Must have passed the qualifying exami-
not declared and their mark sheets are
nation in Single attempt without any backlog Documents required to be submitted
not available latest by 26 July 2018
or failure in any semester from IITs/ NITs/ along with the downloaded application
which is the last date for admission.
CFTI/ SFTI or Central/ State University form:
• The admission procedure for the PhD
b. Has not graduated earlier than one year,
programme consists of an Entrance
and holds rank of I to 10 in his/her graduating The candidates are required to submit fol-
Test followed by an interview. Stu-
branch from where graduated. lowing documents along with the application
dents are required to score at least 50%
form:
marks in both, the Entrance Test and
The minimum COPA/ marks percentage
the interview separately, to be eligible
shall be relaxed by 0.5 CGPA or 5 percent in a. Photocopy of High School Certificate
for admission.
case of candidates belonging to the SC/ ST/ b. Photocopies of all Mark sheets
• Travel Subsidy for Candidates Invited
PwD categories in all cases. c. Certificate of sponsorship in the pre-
for Interview: Candidates invited for
scribed format (if applicable).
the interview will be given a travel sub-
Admission Procedure and Other Details: d. A photocopy of GATE/NET or equivalent
sidy (upper limit INR 5,000) towards
score card
actual travel cost by the shortest route
Admission to the Ph. D. Programme shall e. A photocopy of the certificate of Caste (if South Asian University as per instructions which will be com-
be made by the Institute based on minimum applicable).
eligibility criteria for the programme and PhD Biotechnology municated to those called for interview.
If candidates from outside India are
selected after evaluation of the candidate in Documents required for verification dur- Admissions – 2018-19 unable to travel to New Delhi for the
Screening written Test and/or selection Inter- ing the interview and admission:
interview, they can seek permission for
view conducted by the respective DRC.
an interview through Skype.
Candidates’ name with application num- (i) The candidates are required to bring fol- MSc or MTech degree in any branch of • The pre-PhD course work is compul-
ber, fulfilling minimum eligibility criteria for lowing documents at the time of written Ex- the Biological Sciences or an MD/MS/MSc sory for all students and is spread over
admission to the respective department and amination/ interview: from an institution recognized by the gov- the first two semesters and carries 16
programme will be displayed on the Institute ernment of any of the SAARC countries, credits as follows: course work (14
website as per admission schedule. a. High School Certificate in original. with the minimum marks required are credits) plus seminar and term paper
DRC of the respective department will con- b. Mark sheets of qualifying examination in eligible to apply for the PhD Programme (2 credits). Distribution of credits be-
duct screening written Test and Selection In- original. in Biotechnology offered at SAU. Check tween the first two semesters is decided
terview. The final selection will be done after c. Character Certificate issued b} the Head more details below. by individual Departments / Faculties.
Selection Interview. of the Institution last attended/ from employ-
er. South Asian University (SAU) is an inter-
Following type candidates with minimum d. Certificate of sponsorship in the pre- national university established by the gov-
eligibility qualification are exempted from scribed format (if applicable). ernments of the eight member nations of Next Page>>>>

10
Vol. 02 NO 9 February 27th, 2018.

Some Faculties and Departments may an MPhil degree. vidual countries is not possible
have a slightly higher credit require- • Minimum residency requirement for • Kabul (Afghanistan)
ment depending on their specific needs. PhD is three years after admission. Scholarships & Freeships: • Chittagong and Dhaka (Bangladesh)
Candidates are advised to carefully (http://www.sau.int/admission/2018/schol- • Thimphu (Bhutan)
read Faculty and Department-specific Students pursuing a PhD degree at SAU arships2018.pdf) • Male (Maldives)
requirements online. are full-time students and are not permitted Application Fee, Date and Venues for the • Kathmandu (Nepal)
• At the end of the first year, students to take up full or part-time work during the Entrance Test: • Karachi and Lahore (Pakistan)
with a Cumulative Grade Point Av- residency period. • Colombo (Sri Lanka)
erage (CGPA) less than 5.0 will be An Entrance Test will be conducted simul- • India (Bangalore, Chandigarh, Chen-
deemed to have failed and shall leave Deadline for receiving Application Forms: taneously throughout the SAARC region on nai, Guwahati, Hyderabad, Jaipur, Kol-
the university. There is no provision for 20 March 2018 15 April 2018. The fee for appearing in the kata, Lucknow, Mumbai, New Delhi,
a repeat test for improvement of grades Entrance Test is US $10 or INR 650/-. Appli- Patna and Thiruvananthapuram).
in any pre-PhD course. Country-Wise Quota of Seats: cations for admission will be accepted only
• Students with a CGPA of 6.5 and above online and payment must be made by credit/ Please indicate the centre of your choice
will be considered for direct admission PhD Programmes debit cards or net banking. Those who cannot while filling the application form.
to the PhD programme as per SAU pay the application fee online still need to fill The Entrance Tests will be held in two shifts
regulations. Candidates with a CGPA The available seats in each programme will and submit the online application form. They on the same day at all the centres as shown
above 5.0 but less than 6.5 can opt for be divided as follows: can then courier a bank draft for US$ 10 or below:
the MPhil programme and complete INR 650/- drawn in favour of “South Asian
their thesis work within a year (8 Cred- • Fifty per cent seats for Indian students University” payable at New Delhi to the Dep- Morning Session : PhD in Biotechnology
its). If a student has obtained a CGPA of and the remaining 50% seats for all uty Registrar Admissions, South Asian Uni-
6.5 or above in his/her course work, but other seven SAARC countries put to- versity, Akbar Bhawan, Chanakyapuri, New A student can register for 2 or more courses
wishes to pursue the MPhil programme gether. Delhi 110021, India. The bank draft must but will be allowed to take the Entrance Test
rather than the PhD programme, s/he • Two merit lists will be prepared, one have the name of the candidate, application for 2 subjects at most, one in the morning ses-
will be permitted to do so. Students for Indian applicants and the other will number and the programme applied for at the sion and one in the afternoon.
with a CGPA of 6.5 or more in MPhil be a combined merit list for the remain- back of the bank draft. However, registration
are also allowed to register for the PhD ing SAARC countries. In view of the will be done only on receipt of the bank draft. Application Deadline – 20th March 2018
programme. Students with a CGPA less small number of seats available in each The following is a list of the main cities
than 6.5 will leave the university with programme, seat reservation for indi- where the Entrance Test will be conducted:

JOBS
KENDRIYA VIDYALAYA RECRUITMENT –
2018 | CHECK APPLICATION DETAILS

1. RECRUITMENT @ KENDRIYA 2. KENDRIYA VIDYALAYA RECRUIT- 3. GOVT JOB @ KENDRIYA VIDYA- 4.GOVT TEACHING JOB @ KENDRI-
VIDYALAYA, CHANDIGARH – BIO- MENT – 2018 @ HYDERABAD | GOVT LAYA, MADHYA PRADESH CHHATAR- YA VIDYALAYA, AIR FORCE STATION,
TECH VACANCY BIOLOGY JOB PUR | PGT BIOLOGY VACANCIES BARNALA

Job Title : PGT – Biology & Biotechnol- Job Title : PGT – Biology Job Title : PGT – Biology Job Title : PGT – Biology
ogy
Qualification : Qualification : Qualification :
Eligibility :
Master Degree from a recognized Universi- Master Degree from a recognized Universi- Master Degree from a recognized Universi-
• PGT: English, Hindi, Maths, Physics, ty with atleast 50%marks in aggregate in the ty with atleast 50%marks in aggregate in the ty with atleast 50%marks in aggregate in the
Chemistry, Biology, Geography, Histo- following subjects:PGT (Biology) – Botany/ following subjects:PGT (Biology) – Botany/ following subjects:PGT (Biology) – Botany/
ry, Economics, Commerce & Political Zoology/ Life Sciences/Bio Sciences/ Genet- Zoology/ Life Sciences/Bio Sciences/ Genet- Zoology/ Life Sciences/Bio Sciences/ Genet-
Science – (Master Degree in concerned ics/ Micro Biology/ Bio Technology/ Molec- ics/ Micro Biology/ Bio Technology/ Molec- ics/ Micro Biology/ Bio Technology/ Molec-
subject with 50% marks & B.Ed) ular Bio/Plant Physiology provided they have ular Bio/Plant Physiology provided they have ular Bio/Plant Physiology provided they have
• PGT Bio-Technology: M.Sc/M.Tech studied Botany and Zoology at Graduation studied Botany and Zoology at Graduation studied Botany and Zoology at Graduation
in Biotechnology/M.Sc in Genetics/mi- level. level. level.
crobiology/Life Sciences/Bio Chemis- (https://www.biotecnika.org/2018/02/
try with 50% marks (https://www.biotecnika.org/2018/02/ (https://www.biotecnika. govt-teaching-job-kendriya-vidya-
kendriya-vidyalaya-recruitment-2018-hy- org/2018/02/govt-job-kendriya-vidya- laya-air-force-station-barnala/)
(https://www.biotecnika.org/2018/02/ derabad-govt-biology-job/) laya-madhya-pradesh-pgt-biology-vacan-
recruitment-kendriya-vidyalaya-chandi- cies/)
garh-biotech-vacancy/)

11
February 27th, 2018. Vol. 02 NO 9

GOVT RESEARCH SCIENTIST


VACANCIES @ DIRECTORATE OF
ENVIRONMENT DEPT., HARYANA

Job seekers looking for research oppor- Position I years experience in the field of Environment Qualifications :
tunities in government institute like Direc- Management or in the scale of Rs. 15600-
torate of Environment Dept., Haryana and Name of the Position : Senior Scientist 39100+6400GP M.Sc. Chemistry/Bio-Chemistry having an
you either have a Master’s or PhD Degree experience of 2 years in the field of Environ-
in Botany/Zoology/ Biochemistry, then No.of.Posts : 01 Position II ment Protection and Conservation.
check out all of the details posted below.
Pay Scale : 15000· 39100+ 6600 GP Name of the Position : Scientific Officer How to Apply:
Area of Work : Climate Change Cell of
Environment Department Haryana Qualifications : No.of.Posts : 01 The complete application along with gist
of ACR for last 10 years and certificate from
Ph. D in Environmental Sciences/Bio- Pay Scale : 9300· 34800+ 4600 GP competent Authority should reach this office
Sciences/Chemistry/Botany/Zoology with 5 through proper channel latest by 12.03.2018.

PHD RESEARCH JOB OPENING @ SAHA


INSTITUTE OF NUCLEAR PHYSICS,
KOLKATA

Saha Institute of Nuclear Physics, Kol- Area of Research : Essential Qualifications : How to Apply:
kata hiring for Research Associate. PhD
cell biology, PhD Molecular biology candi- Therapeutic Prevention of Viral Infection. Candidates with a Ph.D. degree in Molecu- Interested candidates are requested to send
dates send applications via email to SINP, lar Biology & Cell Biology who has submit- application materials (Cover letter, Resume,
Kolkata, as Per the details posted below. Tenure : ted his/her thesis for Ph.D. candidates two letters of references) directly to dulal.
senapati@saha.ac.in by email by 13th March,
Name of the Position : Research Associ- Initially for 1 (one) year and is renewable Fellowship : 2018 from the publication of the advertise-
ate position based on the performance. ment.
Rs. 28,000/- per month (consolidated).
No.of.Positions : 01 Age limit : Application Deadline – by 13th March,
2018
Maximum 35 years as on 13.03.2018

PHD BOTANY/MICROBIO/LIFE SCIENCES


JOB VACANCY @ CSIR-IHBT

PhD Jobs at CSIR-IHBT. Botany, Mi- riculture” (OLP-0042) [Upto March, 2019). Application Instructions: testimonials at the time of appearing for the
crobiology, Life Sciences candidates are interview failing which he/she will not be al-
requested to attend the Walk-in-Inter- Stipend (Per month) [Consolidated] : Eligible candidates may appear for “Walk- lowed to appear for interview. No TA will be
view that is scheduled to be held on the in-lnterview(s)” on the date, time and place paid for attending the interview.
date(s) as mentioned below at CSIR-IHBT, Rs. 36,000/- p.m. mentioned above along with an application
Palampur: on prescribed format which is available on • Walk-In Details:
Maximum Age the CSIR-IHBT, website “www.ihbt.res.in” •
Job Titles : Project Assistant Level-II (As on date of Interview) : along with attested photocopies of testimo- • Date of Interview – 26.02.2018
nials of their age, educational qualifications, • Time of Interview – 09:30 AM
No.of.Posts : 01 35 years as on 26.02.2018 experience, reserved category, etc. at the time • Venue of Interview – CSIR-IHBT,
of interview. The positions are purely tem- Palampur (H.P)
Project Title : porary and co-terminus with the duration of
Essential Qualifications : the project. There will be no right implicit
“Development of microbial formulations or explicit for regular position or any post in
to serve as stress buster and bio-fertilizer for PhD in Botany/ Microbiology/ Life Scienc- CSIR-IHBT, whatsoever. Candidates must
improving crop productivity in stressed ag- es also bring with them original certificates of

12

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