The document describes the anatomy of the base of the skull, including the divisions and contents of the anterior, middle, and posterior cranial fossae. It discusses structures such as the pituitary fossa, cavernous sinus, optic canals, and various foramina. The pituitary gland derives from two embryonic origins and develops in the sella turcica of the middle cranial fossa. Cranial nerves and blood vessels pass through the cavernous sinus, which contains the internal carotid artery.
The document describes the anatomy of the base of the skull, including the divisions and contents of the anterior, middle, and posterior cranial fossae. It discusses structures such as the pituitary fossa, cavernous sinus, optic canals, and various foramina. The pituitary gland derives from two embryonic origins and develops in the sella turcica of the middle cranial fossa. Cranial nerves and blood vessels pass through the cavernous sinus, which contains the internal carotid artery.
The document describes the anatomy of the base of the skull, including the divisions and contents of the anterior, middle, and posterior cranial fossae. It discusses structures such as the pituitary fossa, cavernous sinus, optic canals, and various foramina. The pituitary gland derives from two embryonic origins and develops in the sella turcica of the middle cranial fossa. Cranial nerves and blood vessels pass through the cavernous sinus, which contains the internal carotid artery.
Anatomy of the base of the skull, the pituitary fossa and the cavernous sinus
Divisions of the fossae
Anterior vs middle o Anterior border is the brim of the frontal bone o posterior border of the anterior cranial fossa: lesser wing sphenoid o Anterior clinoid processes lie “above” the optic canals o Lesser wing sphenoid “sits” in the lateral sulcus of the cortex Middle vs posterior o anterior: dorsum sellae (median rectangular plate) and the posterior clinoid processes (foot of the bed) o lateral: superior ridge of the petrous temporal bone
Contents of the fossae
Anterior cranial fossa o Crista galli Expansion of the ethmoid bone Attaches the anterior aspect of the falx cerebri (dura) o Cribiform plate Penetrations of the olfactory nerves o Ethmoidal foraminae Anterior and posterior ethmoidal nerves Seen from orbit o Orbital plate of the frontal bone forms most of the floor Middle cranial fossa (median) o 4 clinoid processes – wings of sphenoid, dorsum sellae o Optical canal and associated groove o The sella turcica (hypophyseal fossa) – the “turkish saddle” Body of the sphenoid bone Pituitary gland sits here, covered by dura sella o Foramen lacerum Not a true foramen, nothing traverses it entirely (things enter and exit via canals in the the walls of the foramen) Apertures for the Carotid canal (ICA) Pterygoid canal (greater petrosal nerve) Greater petrosal nerve (of CNVII) passes into foramen lacerum --> pterygoid canal --> pterygopalatine fossa
o Superior orbital fissure
III, IV, V1, VI o Foramen rotundum V2 --> pterygopalatine fossa o Foramen ovale V3 Lesser petrosal nerve --> infratemporal fossa (parasympathetic to otic ganglion) o Foramen spinosum Middle meningeal --> infratemporal fossa o Cavernous sinus – see later Posterior cranial fossa o Foramen magnum Most inferior portion of the PCF o Hypoglossal canal Jugular foramen Exit of the hypoglossal nerve, within walls of foramen magnum o Jugular foramen Exit of vagus, glossopharyngeal, and accessory nerves Figure 8 shape for the formation site of the IJV (saggital sinus, inferior petrosal sinus) o Internal auditory meatus Exit of facial nerve and vestibulocochlear nerves o Clivus Basal portion of the occipital bone and the body of the sphenoid o Internal occipital crest Attaches the posterior portion of the falx cerebri
Pituitary gland (middle cranial fossa)
2 embryological origins o Oral cavity (pharyngeal tissue) o Hypothalamus (neural tissue) Two outgrowths of each tissue develop at ~day 42 o Rathke’s pouch (oral) o Neurohypophyseal bud (neual) The outgrowth from the oral cavity grows towards the neurohypophyeal bud and by ~day60, loses its connection to the oral cavity o Piece of tissue that was part of the GIT is loosely attached to the outbud of the developing hypothalamus Therefore the pituitary has the following strucures o Anterior lobe – associated with CNS via vascular connections o Posterior lobe – associated with CNS via neural connections Bone forms around the bud at ~3 months
Cavernous sinus (middle cranial fossa)
Lies between 2 layers of dura Joined in the midline, allowing passage of venous blood across the midline o Anterior intercavernouse sinus o Posterior intercavernous sinus BETWEEN the layers o III, VI, V1, VI (sometimes some V2) Note the abducent CNVI lies close to the ICA o Internal carotid artery Heads anteriorly within the cavernous sinus, doubles back on itself to pierce the dura and branches to supply intracranial branches o Sympathetic plexii (for structures of the head) OUTSIDE the layers (between bone and bony dural surface) o Middle meningeal artery o Petrosal nerves (parasympathetics) INSIDE both layers (brain side) o Optic chiasm, optic nerve o Pituitary gland (intradural structure) o Temporal lobe of cortex Important: pituitary has close association with the ICA, abducent, and venous drainage of the eye. Things that happen to the pituitary have the potential to affect structures of the cavernous sinus. Image: o * sphenoidal sinus (air) o A = pituitary, arrow = infundibulum o C = optic chiasm o I = ICA both in the cavernous sinus and intracranial portion
More anterior view (towards anterior clinoid process)
ICA has branched to form ophthalmic artery Adjacent ophthalmic vein Nerves through SOF
Lateral aspect of the cavernous sinus (remove brain surface of dura) and contents of the middle cranial fossa Petrosal nerves
Greater petrosal nerve- parasympathetic fibres.
Branch of the FACIAL nerve (origin: superior salivary nucleus) at the geniculate nucleis (no synapse) Travels below the trigeminal ganglion Exits via the foramen laceum (upper aperture) Travels through the pterygoid canal into the pterygopalatine fossa Synapses on pterygopalatine ganglion (within pterygopalatine ganglion) Supplies: o Lacrimal (tears) – via V2 (hitchike as V2 passes through the pterygopalatine fossa, then from V2 to V1 within the orbit) o Nasal (mucus) – diverge after ganglion to supply mucosa of concha o Palatine glands (mucus)– hard and soft palate
Lesser petrosal nerve
A branch of the GLOSSOPHARYNGEAL nerve, exiting skull through jugular foramen Traverses tympanic plexus, travels lateral to the greater petrosal nerve Exits via foramen ovale, travels infratemproal fossa to find and... Synapses on otic ganglion