PATHOPHYSIOLOGY (Client Centered)

Modifiable Non modifiable

 Diet (Dairy  Age 30-60
products, spicy  Gender (Male)
food, caffeine
0  Having O blood
 Excessive alcohol type
ingestion
Gastric mucus become  Bile Reflux
 Smoker
edematous and
 Stress
hyperemic (congested
 NSAIDS
with blood and fluid

 Stress Gastric mucus membrane

undergoes superficial
obstruction

Increased hydrochloric acid

(HCL) production

Irritation of the lining Inflammatory

c (mucosal) of the stomach, process
duodenum, proximal of small
intestine

Damage of mucosal Barrier

S/Sx: 03-01-18

Abdominal pain
Decreased function of
mucosal cells decreased
quality of mucus loss of tight
junctions between cells

Back diffusion of acid into

gastric mucosa
A B
 A B

Conversion of pepsinogen to Formation of liberation

pepsin of histamine
Increase acid
c secretion

Further mucosal erosion Local vasodilation

destruction of blood
Stimulation of cholinergic
intramural plexus, causing
muscles spams
Mucosal injury
Ulceration Increased capillary
permeability loss of
proteins mucosal
edema loss of
plasma into gastric
Bleeding / Hemorrhage S/sx: 02-28-18
lumen
black tarry stool ,

Decreased oxygen carrying

capacity as manifested by
decreased hemoglobin and
hematocrit level

Sign and symptoms of

anemia

03-02-18 03-02-18

Hematocrit Hemoglobin

27.2 8.5 g/dl

S/sx: 03- S/sx: 03- S/sx: 03-01-18 S/sx: 03-01-18

S/sx: 03-01-18
01-18 01-18
Light headed Low blood
Tachycardia
Pallor Weakness ness pressure

(100/60)