You are on page 1of 71

Mental Health and

Occupational Balance in Stroke


Improving the Mental Health of Stroke Survivors

Sam Talisman, OTD, OTR


Washington University School of Medicine
Program in Occupational Therapy
Goals for Today
•  Understand the impact of mental health on stroke
survivors’ engagement and performance in daily
occupations.
•  Identify mental health challenges people with physical disabilities may
face.
•  Relate mental health issues to problems with occupational
performance.

•  Appraise interventions designed to improve the mental


health of stroke survivors.

Washington University School of Medicine


Program in Occupational Therapy
INTRODUCTION

Washington University School of Medicine


Program in Occupational Therapy
What do we know about mental health?

•  How do we define it?

•  What does it look like?

•  What do we do if it’s good? If it’s bad?

Washington University School of Medicine


Program in Occupational Therapy
Language Surrounding Mental Health
•  World Health Organization
•  “Mental health is defined as a state of well-being in which every
individual realizes his or her own potential, can cope with the normal
stresses of life, can work productively and fruitfully, and is able to
make a contribution to her or his community.” (WHO, 2014)

•  OTPF: body functions ! mental functions (AOTA, 2014)

•  Other professions

Washington University School of Medicine


Program in Occupational Therapy
Division of Mental and Physical

•  Health: “a state of complete physical, mental, and social


well-being and not merely the absence of disease or
infirmity” (WHO, 1948)

•  Clinical divisions- “mental health settings”

•  Professional divisions

Washington University School of Medicine


Program in Occupational Therapy
Health v. Illness

Unhealthier Healthier

Illness No Illness

Washington University School of Medicine


Program in Occupational Therapy
Post-Stroke Mental Health

Disorders:

•  Depression (Morrison, Pollard, Johnston, & MacWalter, 2005; Chen, Tsai, Chung, Chen, Wu, &
Chen, 2015)

•  Anxiety (Hackett, Köhler, O’Brien, & Mead, 2014; Ferro, Caeiro, & Santos, 2009; Campbell Burton et
al., 2013)

•  Others

Washington University School of Medicine


Program in Occupational Therapy
Post-Stroke Mental Health

Sub-threshold of a disorder- examples:

•  Emotional Lability (Hackett, Köhler, O’Brien, & Mead, 2014)

•  Lowered Self-Esteem (Vickery, Evans, Lee, Sepehri, & Jabeen, 2009)

•  Loss of Sense of Self (DeJean, Giacomini, Vanstone, & Brundisini, 2013)

•  Apathy (Hackett, Köhler, O’Brien, & Mead, 2014)

Washington University School of Medicine


Program in Occupational Therapy
Pathology

•  Psychological
•  Stroke is a stressful life event
•  Fear of the unknown

•  Neurological
•  Reorganized brain
•  Washington Post: “After a stroke, her decades of severe depression
vanished” (March 11, 2018)

Washington University School of Medicine


Program in Occupational Therapy
Cycle of Stroke and Mental Health

Stroke

Decreased
MH Issues
Health

Decreased
Function

Washington University School of Medicine


Program in Occupational Therapy
Cycle of Stroke and Mental Health
Stroke

Decreased
Occupational
MH Issues
Health Issues

Decreased
Function

Washington University School of Medicine


Program in Occupational Therapy
MENTAL HEALTH EFFECTS

Washington University School of Medicine


Program in Occupational Therapy
Occupational Issues
Mental health issues decrease occupational engagement after
a stroke.

Why?
•  Functional impairment (Gillen, 2011)

•  Decreased motivation (Hackett, Köhler, O’Brien, & Mead 2014; Frost, Weingarden, Zeilig,
Nota, & Rand, 2015)

Washington University School of Medicine


Program in Occupational Therapy
Occupational Issues
•  ADLs/IADLs (Coenen et al., 2016)

•  Work (Matuska & Barrett, 2016)

•  Caregiving (Coenen et al., 2016)

•  Social Participation (Woodman, Riazi, Pereira, & Jones, 2014)

Washington University School of Medicine


Program in Occupational Therapy
Cognitive

Stress acts as a cognitive load. (Stawski, Sliwinski, & Smyth, 2006)

This can cause a cycle between mental health and


occupational performance.

Changes in cognition can go unnoticed and unreported. (Knopman


et al., 2009)

Washington University School of Medicine


Program in Occupational Therapy
Cognitive
•  Processing speed

•  Language

•  Visuospatial ability

•  Memory (Campbell, Marriott, Nahmias, & MacQueen, 2004)

•  Attention

•  Executive functioning (Park et al., 2015; Royall, Palmer, Chiodo, & Polk, 2004; Muir et
al., 2015)

Washington University School of Medicine


Program in Occupational Therapy
Physiological

The brain and the body influence each other.

Stress: mental ! physical (Truelsen, Nielsen, Boysen, & Grønbæk, 2003)

Pain: mental ! physical (Kross, Berman, Mischel, Smith, & Wager, 2011)

Washington University School of Medicine


Program in Occupational Therapy
Physiological

•  Sleep (Nakase, Tobisawa, Sasaki, & Suzuki, 2016)

•  Appetite

•  Fitness (Lerdal & Gay, 2013; Tang et al., 2010)

•  Sexual functioning (Balon, 2007; Kennedy & Rizvi, 2009; Hattjar, 2012)

Washington University School of Medicine


Program in Occupational Therapy
Motor
Lower post-stroke participation in therapy and occupations
means less motor recovery.

Why lower?

•  Functional impairment (Gillen, 2011)

•  Decreased motivation (Subramanian, Lourenço, Chilingaryan, Sveistrup, & Levin, 2013;


Kramer, Johnson, Bernhardt, & Cumming, 2016)

Washington University School of Medicine


Program in Occupational Therapy
Motor

•  Sensory feedback (Subramanian, Chilingaryan, Sveistrup, & Levin, 2015)

•  UE function

•  LE function
•  The role of self-efficacy: self-fulfilling prophecy (Schmid et al., 2012)
•  Fear of falling cycle (Delbaere, Crombez, Vanderstraeten, Willems, & Cambier, 2004)

Washington University School of Medicine


Program in Occupational Therapy
Spiritual

Spirituality ties directly to a person’s self-expression and


engagement in their life. (Eakmann, 2016)

Positive spirituality can improve mental health and


occupational functioning. (Pargament, Koenig, Tarakeshwar, & Hahn, 2004; Giaquinto,
Spiridigliozzi, & Caracciolo, 2007)

Negative spirituality can have the opposite effect. (McConnell,


Pargament, Ellison, & Flannelly, 2006; Abu-Raiya, Pargament, & Exline, 2015; Fitchett et al., 2004)

Washington University School of Medicine


Program in Occupational Therapy
Spiritual
Factors to overcome:

•  Limited occupational engagement

•  Limited relationships (Puchalski et al., 2009)

•  Poor coping and spiritual struggles (McConnell, Pargament, Ellison, & Flannelly,
2006)

Washington University School of Medicine


Program in Occupational Therapy
Social Support

More disability + MH issues = lower social support (Kamenov et al.,


2016)

Depression limits the benefits others typically gain from any


social support available.

Washington University School of Medicine


Program in Occupational Therapy
Social Support

•  Actual v. perceived support (Northcott, Moss, Harrison, & Hilari, 2016)

•  Caregiver burden (Han & Haley, 1999; Jönsson, Lindgren, Hallström, Norrving, & Lindgren,
2005)

•  Social participation (Northcott, Moss, Harrison, & Hilari, 2016; Northcott & Hilari, 2011)

Washington University School of Medicine


Program in Occupational Therapy
Technology

Well-prescribed AT can improve mental health. (Scherer & Glueckauf,


2005)

Poorly prescribed AT can damage mental health. (Scherer & Glueckauf,


2005)

Proper prescription must consider a person’s self-image and


related concerns. (Pape, Kim, & Weiner, 2002)

Washington University School of Medicine


Program in Occupational Therapy
Physical Environment
•  Discharge location influences motivation (Holmqvist & von Koch, 2001;
Åstrand et al., 2016; Vanroy et al., 2016)

•  Green space (Van den Berg, Maas, Verheij, & Groenewegen, 2010)

•  Noise (Snögren & Sunnerhagen, 2009)

•  Pollution (Wilker et al., 2013)

•  Physical and structural barriers (Zhang, Yan, You, Li, & Gao, 2016; Zhang, Sui,
Yan, You, Li, & Gao, 2017)

Washington University School of Medicine


Program in Occupational Therapy
Mental Health Cycles
•  MH issues contribute to:
•  Lower occupational performance and engagement
•  Cognitive deficits
•  Physiological dysfunction
•  Motor problems
•  Spiritual struggles
•  Decreased social support
•  Resistance to technology
•  Poor physical environment

…Which then lead to further MH issues.

Washington University School of Medicine


Program in Occupational Therapy
Cycle of Stroke and Mental Health-
Revisited
Stroke

Decreased
Occupational
MH Issues
Health Issues

Decreased
Function

Washington University School of Medicine


Program in Occupational Therapy
Mental Health and Occupational Balance

•  Mental health as a cycle

•  MH as a change agent

•  MH as balance

Washington University School of Medicine


Program in Occupational Therapy
PEOP: Enabling Everyday Living
THE NARRATIVE PERSON OCCUPATION ENVIRONMENT
The past, current and future " Cognition • Cultural Environment
perceptions, choices, interests,
•  Activities.Tasks,Roles
" Psychological • Classifications • Social Support
goals and needs that are unique " Physiological • Social Determinants and
to the Person, Organization or " Sensory/Perceptual Social Capital
Population " Motor • Health Education and Public Policy
" Spirituality/Meaning • Physical and Natural Environment
Personal Narrative • Assistive Technology
Perceptions and Meaning
Choices and
Responsibilities
Attitudes and Motivations
Needs and Goals

PERFORMANC
Organizational Person Environment

PARTICIPATION
Narrative
Mission and History
Focus and Priorities

BEING
WELL-
Stakeholders and Values
Needs and Goals

Population/

E
Community Narrative
Environments and Occupation
Behaviors
Demographics and
Disparities Incidence and
Prevalence
Needs and Goals
The performance of occupation (doing) enables the participation (engagement) in every day life
that contributes to a sense of well-being (satisfaction)
Model of Mental Health and Occupational
Balance in Stroke (MHOBS)

Individual

Mental
Health

Occupation

Intrinsic Extrinsic

Washington University School of Medicine


Program in Occupational Therapy
Out of Balance

Individual

Mental
Health

Occupation

Intrinsic Extrinsic
Washington University School of Medicine
Program in Occupational Therapy
NOT LIMITED TO STROKE
•  Cancer (Vanderwerker, Laff, Kadan-Lottick, McColl, & Prigerson, 2005)

•  TBI (Andelic, Sigurdardottir, Schanke, Sandvik, Sveen, & Roe, 2010)

•  SCI (Migliorini, Tonge, & Taleporos, 2009)

•  Heart attack (Schleifer & Macari-Hinson, 1989)

•  More!

Washington University School of Medicine


Program in Occupational Therapy
ASSESSMENTS

Washington University School of Medicine


Program in Occupational Therapy
Measures
•  Activity Card Sort (ACS)
•  Canadian Occupational Performance Measure (COPM)
•  Executive Function Performance Test (EFPT)
•  Hospital Anxiety and Depression Scale (HADS)
•  Patient Health Questionnaire (PHQ-9)
•  Medical Outcomes Study Short Form 36 (SF-36)
•  Spirituality Index of Well-Being (SIWB)
•  Quality of Life in Neurological Disorders
Measurement System (Neuro-QoL)
•  World Health Organization’s Quality of Life-BREF
(WHOQOL-BREF)
•  Craig Hospital Inventory of Environmental Factors (CHIEF)

Washington University School of Medicine


Program in Occupational Therapy
Hospital Anxiety and Depression Scale
(HADS)
•  Two 7-question subscales
•  Anxiety
•  Depression

•  4-point Likert scale


•  Absence < - - > extreme presence of symptoms

•  Validated beyond hospital settings

Washington University School of Medicine


Program in Occupational Therapy
Patient Health Questionnaire (PHQ-9)
•  9-question screen
•  Symptoms of depression

•  4-point Likert scale


•  Not at all < - - > nearly every day

•  Breaks scores into:


•  Mild (5)
•  Moderate (10)
•  Moderately severe (15)
•  Severe (20)

Washington University School of Medicine


Program in Occupational Therapy
Neurological Quality of Life (Neuro-QOL)
•  Multiple long-form and short-form questionnaires

•  5-point Likert scale

•  Domains:
•  Physical
•  Mental
•  Social

•  Specifically for people with neurological conditions

Washington University School of Medicine


Program in Occupational Therapy
World Health Organization’s Quality of Life-
BREF (WHOQOL-BREF)
•  26-question assessment

•  5-point Likert scale

•  Measures quality of life:


•  Physical health
•  Psychological health
•  Social relationships
•  Environment

Washington University School of Medicine


Program in Occupational Therapy
INTERVENTIONS

Washington University School of Medicine


Program in Occupational Therapy
Mental Health Considerations

Stay occupation-focused! Identify goals and barriers to


meaningful occupations.

Screen for disorders and mental health changes to determine


need.

Consider how mental health is related to other issues that


may arise or are already there.

Washington University School of Medicine


Program in Occupational Therapy
Mental Health Considerations
•  Think about recovery potential based on effort

•  Facilitate competency and give feedback (Eakmann, 2016)

•  Improve autonomy

•  Encourage belonging and social support

•  Advocacy- individual and community

Washington University School of Medicine


Program in Occupational Therapy
Conclusions

Mental health isn’t a separate issue- it’s related to everything.

Staying occupation-based will improve mental health along


with other outcomes.

We all have simple tools to use to address mental health in


every day practice. Now, let’s use them!

Washington University School of Medicine


Program in Occupational Therapy
Acknowledgements
•  Dr. Carolyn M. Baum, PhD, OTR, FAOTA

•  Lauren Milton, OTD, OTR/L

•  Patricia Nellis, OTD, OTR/L

•  Washington University OTD Class of 2017

Washington University School of Medicine


Program in Occupational Therapy
References
•  Abu-Raiya, H., Pargament, K. I., & Exline, J. J. (2015). Understanding and addressing religious and spiritual struggles in health care. Health & Social
Work, 40(4), e126-e134.
•  American Occupational Therapy Association (2014). Occupational Therapy Practice Framework: Domain & Process, 3rd Edition. American Journal of
Occupational Therapy, 68, S1-S48.
•  Andelic, N., Sigurdardottir, S., Schanke, A. K., Sandvik, L., Sveen, U., & Roe, C. (2010). Disability, physical health and mental health 1 year after
traumatic brain injury. Disability and Rehabilitation, 32(13), 1122-1131.
•  Åstrand, A., Saxin, C., Sjöholm, A., Skarin, M., Linden, T., Stoker, A., ... & Cumming, T. (2016). Poststroke physical activity levels no higher in
rehabilitation than in the acute hospital. Journal of Stroke and Cerebrovascular Diseases, 25(4), 938-945.
•  Balon, R. (2007). Depression, antidepressants, and human sexuality. Primary Psychiatry, 14(2), 42-50.
•  Baum, C.M., Christiansen, C.H., & Bass, J.D. (2015). The Person-Environment-Occupation-Performance (PEOP) model. In Christiansen, C.H., Baum,
C.M., & Bass, J.D. (Eds.), Occupational therapy: Performance, participation, and well-being (4th ed.). Thorofare, NJ: Slack.
•  Campbell, S., Marriott, M., Nahmias, C., & MacQueen, G. M. (2004). Lower hippocampal volume in patients suffering from depression: A meta-
analysis. American Journal of Psychiatry, 161(4), 598-607.
•  Campbell, Burton, C., Murray, J., Holmes, J., Astin, F., Greenwood, D., & Knapp, P. (2013). Frequency of anxiety after stroke: A systematic review
and meta‐analysis of observational studies. International Journal of Stroke, 8(7), 545-559.
•  Chen, C. M., Tsai, C. C., Chung, C. Y., Chen, C. L., Wu, K. P., & Chen, H. C. (2015). Potential predictors for health-related quality of life in stroke
patients undergoing inpatient rehabilitation. Health and Quality of Life Outcomes, 13(1), 1.
•  Coenen, M., Cabello, M., Umlauf, S., Ayuso-Mateos, J. L., Anczewska, M., Tourunen, J., ... & Cieza, A. (2016). Psychosocial difficulties from the
perspective of persons with neuropsychiatric disorders. Disability and Rehabilitation, 38(12), 1134-1145.
•  DeJean, D., Giacomini, M., Vanstone, M., & Brundisini, F. (2013). Patient experiences of depression and anxiety with chronic disease: A systematic
review and qualitative meta-synthesis. Ontario Health Technology Assessment Series, 13(16), 1-33.
•  Delbaere, K., Crombez, G., Vanderstraeten, G., Willems, T., & Cambier, D. (2004). Fear-related avoidance of activities, falls and physical frailty: A
prospective community-based cohort study. Age and Ageing, 33(4), 368-373.
•  Eakmann, A. M. (2016). Person factors: Meaning, sense-making & spirituality. In C.H. Christiansen & C.M. Baum (Eds.), Occupational therapy:
Performance, participation and well-being (pp. 313-331). Thorofare, NJ: Slack.
•  Ferro, J. M., Caeiro, L., & Santos, C. (2009). Poststroke emotional and behavior impairment: A narrative review. Cerebrovascular Diseases,
27(Suppl. 1), 197-203.
•  Fitchett, G., Murphy, P. E., Kim, J., Gibbons, J. L., Cameron, J. R., & Davis, J. A. (2004). Religious struggle: Prevalence, correlates and mental
health risks in diabetic, congestive heart failure, and oncology patients. The International Journal of Psychiatry in Medicine, 34(2), 179-196.
•  Frost, Y., Weingarden, H., Zeilig, G., Nota, A., & Rand, D. (2015). Self-care self-efficacy correlates with independence in basic activities of daily
living in individuals with chronic stroke. Journal of Stroke and Cerebrovascular Diseases, 24(7), 1649-1655.
•  Giaquinto, S., Spiridigliozzi, C., & Caracciolo, B. (2007). Can faith protect from emotional distress after stroke?. Stroke, 38(3), 993-997.
•  Gillen, G. (2011). Psychological aspects of stroke rehabilitation. In J. Falk-Kessler, Stroke rehabilitation: A function-based approach (330-347). St.
Louis, MO: Elsevier.

Washington University School of Medicine


Program in Occupational Therapy
References (cont.)
•  Hackett, M. L., Köhler, S., T O'Brien, J., & Mead, G. E. (2014). Neuropsychiatric outcomes of stroke. The Lancet Neurology, 13(5), 525-534.
•  Han, B., & Haley, W. E. (1999). Family caregiving for patients with stroke. Stroke, 30(7), 1478-1485.
•  Hattjar, B. (Ed.). (2012). Sexuality and occupational therapy: Strategies for persons with disabilities. Bethesda, MD: American Occupational
Therapy Association, Inc/AOTA Press.
•  Holmqvist, L.W., & von Koch, L. (2001). Environmental factors in stroke rehabilitation. BMJ, 322(7301), 1501-1502.
•  Jönsson, A. C., Lindgren, I., Hallström, B., Norrving, B., & Lindgren, A. (2005). Determinants of quality of life in stroke survivors and their informal
caregivers. Stroke, 36(4), 803-808.
•  Kamenov, K., Cabello, M., Caballero, F. F., Cieza, A., Sabariego, C., Raggi, A., ... & Ayuso-Mateos, J. L. (2016). Factors related to social support in
neurological and mental disorders. PloS one, 11(2), e0149356.
•  Kennedy, S. H., & Rizvi, S. (2009). Sexual dysfunction, depression, and the impact of antidepressants. Journal of Clinical Psychopharmacology,
29(2), 157-164.
•  Knopman, D. S., Roberts, R. O., Geda, Y. E., Boeve, B. F., Pankratz, V. S., Cha, R. H., ... & Petersen, R. C. (2009). Association of prior stroke with
cognitive function and cognitive impairment: a population-based study. Archives of Neurology, 66(5), 614-619.
•  Kramer, S., Johnson, L., Bernhardt, J., & Cumming, T. (2016). Energy Expenditure and Cost During Walking After Stroke: A Systematic Review.
Archives of Physical Medicine and Rehabilitation, 97(4), 619-632.
•  Kross, E., Berman, M. G., Mischel, W., Smith, E. E., & Wager, T. D. (2011). Social rejection shares somatosensory representations with physical
pain. Proceedings of the National Academy of Sciences, 108(15), 6270-6275.
•  Lerdal, A., & Gay, C. L. (2013). Fatigue in the acute phase after first stroke predicts poorer physical health 18 months later. Neurology, 81(18),
1581-1587.
•  Matuska, K. & Barrett, K (2016) Occupations of adulthood. In Christiansen, C.H., Baum, C.M., & Bass, J.D. (Eds.), Occupational Therapy:
Performance, participation, and well-being (4th ed.). Thorofare, NJ: Slack.
•  McConnell, K. M., Pargament, K. I., Ellison, C. G., & Flannelly, K. J. (2006). Examining the links between spiritual struggles and symptoms of
psychopathology in a national sample. Journal of Clinical Psychology, 62(12), 1469-1484.
•  Migliorini, C., Tonge, B., & Taleporos, G. (2009). Spinal cord injury and mental health. Australian and New Zealand Journal of Psychiatry, 42(4),
309-314.
•  Morrison, V., Pollard, B., Johnston, M., & MacWalter, R. (2005). Anxiety and depression 3 years following stroke: Demographic, clinical, and
psychological predictors. Journal of Psychosomatic Research, 59(4), 209-213.
•  Muir, R. T., Lam, B., Honjo, K., Harry, R. D., McNeely, A. A., Gao, F. Q., ... & Zhou, X. J. (2015). Trail Making Test elucidates neural substrates of
specific poststroke executive dysfunctions. Stroke, 46(10), 2755-2761.
•  Nakase, T., Tobisawa, M., Sasaki, M., & Suzuki, A. (2016). Outstanding symptoms of poststroke depression during the acute phase of stroke. PLoS
ONE, 11(10), 1-13.

Washington University School of Medicine


Program in Occupational Therapy
References (cont.)
•  Pape, T.L.B., Kim, J., & Weiner, B. (2002). The shaping of individual meanings assigned to assistive technology: A review of personal factors.
Northcott, S., & Hilari, K. (2011). Why do people lose their friends after a stroke?. International Journal of Language & Communication Disorders,
46(5), 524-534.
•  Northcott, S., Moss, B., Harrison, K., & Hilari, K. (2016). A systematic review of the impact of stroke on social support and social networks:
associated factors and patterns of change. Clinical Rehabilitation, 30(8), 811-831.
•  Disability and Rehabilitation, 24(1-3), 5-20.
•  Pargament, K. I., Koenig, H. G., Tarakeshwar, N., & Hahn, J. (2004). Religious coping methods as predictors of psychological, physical and spiritual
outcomes among medically ill elderly patients: A two-year longitudinal study. Journal of Health Psychology, 9(6), 713-730.
•  Park, Y. H., Jang, J. W., Park, S. Y., Wang, M. J., Lim, J. S., Baek, M. J., ... & Kim, S. (2015). Executive function as a strong predictor of recovery
from disability in patients with acute stroke: a preliminary study. Journal of Stroke and Cerebrovascular Diseases, 24(3), 554-561.
•  Puchalski, C., Ferrell, B., Virani, R., Otis-Green, S., Baird, P., Bull, J., ... & Pugliese, K. (2009). Improving the quality of spiritual care as a
dimension of palliative care: The report of the Consensus Conference. Journal of Palliative Medicine, 12(10), 885-904.
•  Rowan, A. (2018, March 11). After a stroke, her decades of severe depression vanished. The Washington Post. Retrieved from
https://www.washingtonpost.com/national/health-science/after-a-stroke-her-decades-of-severe-depression-vanished/2018/03/09/
f3791460-06c9-11e8-8777-2a059f168dd2_story.html?utm_term=.27872c9bc67f
•  Royall, D. R., Palmer, R., Chiodo, L. K., & Polk, M. J. (2004). Declining executive control in normal aging predicts change in functional status: The
Freedom House Study. Journal of the American Geriatrics Society, 52(3), 346-352.
•  Scherer, M.J., & Glueckauf, R. (2005). Assessing the benefits of assistive technologies for activities and participation. Rehabilitation Psychology,
50(2), 132-141.
•  Schleifer, S. J., & Macari-Hinson, M. M. (1989). The nature and course of depression following myocardial infarction. Archives of Internal Medicine,
149(8), 1785-1789.
•  Schmid, A. A., Van Puymbroeck, M., Altenburger, P. A., Dierks, T. A., Miller, K. K., Damush, T. M., & Williams, L. S. (2012). Balance and balance
self-efficacy are associated with activity and participation after stroke: A cross-sectional study in people with chronic stroke. Archives of Physical
Medicine and Rehabilitation, 93(6), 1101-1107.
•  Snögren, M., & Sunnerhagen, K.S. (2009). Description of functional disability among younger stroke patients: Exploration of activity and
participation and environmental factors. International Journal of Rehabilitation Research, 32(2), 124-131.
•  Stawski, R. S., Sliwinski, M. J., & Smyth, J. M. (2006). Stress-related cognitive interference predicts cognitive function in old age. Psychology and
Aging, 21(3), 535-544.
•  Subramanian, S. K., Chilingaryan, G., Sveistrup, H., & Levin, M. F. (2015). Depressive symptoms influence use of feedback for motor learning and
recovery in chronic stroke. Restorative Neurology and Neuroscience, 33(5), 727-740.
•  Subramanian, S. K., Lourenço, C. B., Chilingaryan, G., Sveistrup, H., & Levin, M. F. (2013). Arm motor recovery using a virtual reality intervention
in chronic stroke randomized control trial. Neurorehabilitation and Neural Repair, 27(1), 13-23.
•  Tang, W. K., Lu, J. Y., Chen, Y. K., Mok, V. C., Ungvari, G. S., & Wong, K. S. (2010). Is fatigue associated with short-term health-related quality of
life in stroke? Archives of Physical Medicine and Rehabilitation, 91(10), 1511-1515.

Washington University School of Medicine


Program in Occupational Therapy
References (cont.)
•  Truelsen, T., Nielsen, N., Boysen, G., & Grønbæk, M. (2003). Self-reported stress and risk of stroke: The Copenhagen City Heart Study. Stroke,
34(4), 856-862.
•  van den Berg, A.E., Maas, J., Verheij, R.A., & Groenewegen, P.P. (2010). Green space as a buffer between stressful life events and health. Social
Science & Medicine, 70(8), 1203-1210.
•  Vanderwerker, L. C., Laff, R. E., Kadan-Lottick, N. S., McColl, S., & Prigerson, H. G. (2005). Psychiatric disorders and mental health service use
among caregivers of advanced cancer patients. Journal of Clinical Oncology, 23(28), 6899-6907.
•  Vanroy, C., Vissers, D., Vanlandewijck, Y., Feys, H., Truijen, S., Michielsen, M., & Cras, P. (2016). Physical activity in chronic home-living and sub-
acute hospitalized stroke patients using objective and self-reported measures. Topics in Stroke Rehabilitation, 23(2), 98-105.
•  Vickery, C. D., Evans, C. C., Lee, J. E., Sepehri, A., & Jabeen, L. N. (2009). Multilevel modeling of self-esteem change during acute inpatient stroke
rehabilitation. Rehabilitation Psychology, 54(4), 372-380.
•  Wilker, E.H., Mostofsky, E., Lue, S.H., Gold, D., Schwartz, J., Wellenius, G.A., & Mittleman, M.A. (2013). Residential proximity to high-traffic
roadways and poststroke mortality. Journal of Stroke and Cerebrovascular Diseases, 22(8), e366-e372.
•  Woodman, P., Riazi, A., Pereira, C., & Jones, F. (2014). Social participation post stroke: A meta-ethnographic review of the experiences and views
of community-dwelling stroke survivors. Disability and Rehabilitation, 36(24), 2031-2043.
•  World Health Organization (2014, August). Mental health: A state of well-being. Retrieved from
http://www.who.int/features/factfiles/mental_health/en/
•  Zhang, L., Sui, M., Yan, T., You, L., Li, K., & Gao, Y. (2017). A study in persons later after stroke of the relationships between social participation,
environmental factors and depression. Clinical Rehabilitation, 31(3), 394-402.
•  Zhang, L., Yan, T., You, L., & Li, K. (2015). Barriers to activity and participation for stroke survivors in rural China. Archives of Physical Medicine
and Rehabilitation, 96(7), 1222-1228.

Washington University School of Medicine


Program in Occupational Therapy
Interventions for Stroke Survivors
with Depressive Disorders

Brian Chen, OT/S


Washington University School of Medicine
Program in Occupational Therapy
Overview
1.  Therapeutic Exercise Program (Lai et al., 2006)
2.  Dense Cranial Electroacupuncture Stimulation (Man et al., 2014)
3.  Brief Psychosocial Behavioral Intervention (Mitchell et al., 2009)
4.  Upper Extremity Aerobic Exercise (Topcuoglu, Ordu Gokkaya, Halil, &
Karakuş, 2015)

5.  Motivational Interviewing (Watkins et al., 2007)(Watkins et al., 2011)


6.  Transitional Care Program (Wong & Yeung, 2017)

Washington University School of Medicine


Program in Occupational Therapy
Therapeutic Exercise Program (Lai et al., 2006)

•  Progressive exercise program targeting strength, balance,


endurance, and upper extremity function to encourage
more use of the affected extremities
•  Dosage: 90 minute session, 3 times/week, for 12 to 14
weeks (total 36 sessions)
•  Supervised by physical therapist or occupational therapist
•  Includes structured protocols for exercise tasks, criteria for
progression, and guidelines for reintroducing therapy after
intercurrent illness

Washington University School of Medicine


Program in Occupational Therapy
GDS, SIS Emotion, and MOS 36 SF Emotions scores at baseline, postintervention, and follow-up after Exercise
versus UC (Lai et al., 2006)

GDS SIS Emotion MOS 36 SF Emotions

Exercise Usual Care Exercise Usual Care Exercise Usual Care

n=44 n=49 n=44 n=49 n=44 n=49


Baseline
3.4 ± 2.8 3.8 ± 2.7 81 ± 14.3 80 ± 14.6 84 ± 30.9 80 ± 35.9

n=44 n=49 n=44 n=49 n=44 n=49


Postintervention (3
month)
2.5 ± 2.5** 4.4 ± 3.4 83.0 ± 12.1* 76.5 ±16.2 93.0 ± 22.5* 77.5 ± 37.9

n=40 n=40 n=40 n=40 n=40 n=40


Follow Up (9 Month)
2.0 ± 1.8 3.4 ± 3.2 81.1 ± 14.1 80.1 ± 16.8 95.8 ± 13.5 85.8 ± 31.9

*p < 0.05; **p < 0.01

GDS = Geriatric Depression Scale; SIS = Stroke Impact Scale; MOS = Medical Outcomes Study 36 Item Short
Form

Washington University School of Medicine


Program in Occupational Therapy
Therapeutic Exercise Program (Lai et al., 2006)

•  Depressive symptoms do not appear to limit gains in


impairments or functional limitations attributable to
exercise
•  Exercise improved depressive symptoms and quality of life
mostly in those with greater initial depressive symptoms

Washington University School of Medicine


Program in Occupational Therapy
Dense Cranial Electroacupuncture
Stimulation (Man et al., 2014)

•  Electrical Stimulation is delivered on a group of acupoints


on the forehead (6), which are innervated by the
trigeminal sensory pathway
•  Acupuncture intervention was conducted for 3 sessions per
week over 4 consecutive weeks while subjects were being
medicated with SSRIs.
•  Both Intervention and Control groups were given SSRIs
and Body Acupuncture
•  Control groups were given sham cranial acupuncture (n-CEA) in which
needles were adhered to the skin rather than inserted.
•  All subjects (in both groups) received rehabilitation therapy
(1-2 sessions/week) when they entered the study and
were allowed to continue during the study

Washington University School of Medicine


Program in Occupational Therapy
Changes in HAMD-17 score from baseline in PSD Subjects (Man et al., 2014)

DCEAS n-CEA
n=23 n=20
Week 1
-1.9 ± 2.3** -0.1 ± 1.9
n=23 n=20
Week 2
-6.8 ± 2.3 -6.5 ± 1.9
n=23 n=20
Post Intervention (week 4)
-11.6 ± 2.3 -11.2 ± 1.9
**p < 0.01
DCEAS = Dense Cranial Electroacupuncture Stimulation; HAMD-17 = 17-item Hamilton
Rating Scale for Depression; n-CEA = Non-invasive Cranial Electroacupuncture

Washington University School of Medicine


Program in Occupational Therapy
Dense Cranial Acupuncture Stimulation (Man et al.,
2014)

•  Subjects of n-CEA group had better treatment outcomes


than DCEAS group on movement disability associated with
daily self-caring activity
•  Although the needle did not pierce through the skin, similar electrical
stimulation was applied
•  Superficial electrical stimulation appeared to be more beneficial in
improving limbic paralysis
•  Effects similar to Transcutaneous Electrical Nerve Stimulation (TENS),
which excites mechanoreceptors and myelinated nerve fibers
•  Suggests greater improvement of DCEAS on PSD was
unlikely due to improvement of movement ability

•  Although this study demonstrated antidepressant efficacy


of acupuncture therapy, the underlying mechanisms are
not yet well delineated
Washington University School of Medicine
Program in Occupational Therapy
Brief Psychosocial Behavioral Intervention
(Mitchell et al., 2009)

•  Rationale: without behavioral change, there would be no


long lasting change from the initial mood elevation seen
with antidepressants
•  Intervention adapted from the “Seattle Protocols,” shown
to reduce disability associated with depression in
Alzheimer’s Disease
•  Taught participants to view depressive symptoms as observable and
modifiable behaviors that are initiated and maintained by person-
environment interactions
•  Taught specific problem solving approaches and solutions to
behavioral challenges were individualized to each person

•  Both Intervention and usual care groups continued their


antidepressant medications, adjusted by their usual care
provider as needed
Washington University School of Medicine
Program in Occupational Therapy
Mean Change in HRSD Over Time and % in remission (HRSD ≤ 9) (Mitchell et al., 2009)

Mean Change in HRSD % in remission (HRSD ≤ 9)

PBI UC PBI UC

n=45 n=53 n=45 n=53


Post Intervention (Week 9)
-9.8 ± 4.9** -3.6 ± 5.6 47** 19

n=46 n=50 n=46 n=50


Follow Up (Week 21)
-8.3 ± 6.8 -6.0 ± 6.5 46* 22

n=44 n=48 n=44 n=48


Follow Up (12 Month)
-9.2 ± 5.7* -6.2 ± 6.4 48* 27

n=34 n=33 n=34 n=33


Follow Up (24 Month)
-11.3 ± 6.5 -9.3 ± 4.7 65 46

** p < 0.001; *p < 0.05


HRSD = Hamilton Rating Scale for Depression; PBI = Psychosocial Behavioral Intervention; UC = Usual Care

Washington University School of Medicine


Program in Occupational Therapy
Brief Psychosocial Behavioral Intervention
(Mitchell et al., 2009)

•  A brief psychosocial-behavioral intervention adjunctive to


antidepressant therapy is highly effective in reducing
depression and achieving remission in the short term with
the effect sustained for up to 2 years
•  Participants in the usual care control group also reduced
their depression over the first year, but did so more slowly
and with a lesser degree of remission

Washington University School of Medicine


Program in Occupational Therapy
Upper Extremity Aerobic Exercise (Topcuoglu, Ordu Gokkaya,
Halil, & Karakuş, 2015)

•  Arm crank ergometry (5 W/min) 5 days a week, 30


minutes a day, for a period of 4 weeks.

•  Complex Regional Pain Syndrome (CPRS) Type 1


physiotherapy program:
•  TENS (shoulder-hand region encompassing the painful region; 100
Hz, 20 min/day), Cold pack (20 min/day), retrograde massage, and
contrast baths
•  Stroke Rehabilitation physiotherapy program
•  therapeutic exercises, neurophysiological exercises, postural
exercises, balance and coordination exercises, and exercises of
activities of daily living

Washington University School of Medicine


Program in Occupational Therapy
Upper Extremity Aerobic Exercise (Topcuoglu, Ordu Gokkaya,
Halil, & Karakuş, 2015)

•  There was a statistically significant difference between the


treatment groups and UEAE were less depressed when
compared to the ST group (p = 0.005)

Washington University School of Medicine


Program in Occupational Therapy
Motivational Interviewing (Watkins et al., 2007) (Watkins et al., 2011)

•  Four 30 to 60 minute sessions

•  Therapists elicit patients’ personal, realistic goals for


recovery and perceived barriers to attaining these.
•  By working with patients’ dilemmas and ambivalence, and
through supporting and reinforcing optimism and self-
efficacy, therapists enabled patients to identify their own
solutions

•  All patients received usual medical, nursing, and therapy


input, including inpatient care and discharge planning
through multidisciplinary team meetings and a stroke
review clinic appointment at 1, 3, and 6 months post
stroke
Washington University School of Medicine
Program in Occupational Therapy
Effects of Early Motivational Interviewing on mood (Watkins et al., 2007; 2011)

Not often feeling sad or depressed


Normal mood (GHQ-28 < 5)
(Yale)
n (%)
n (%)

MI UC MI UC

n=195 n=197 n=197 n=200


Baseline
72 (36.9%) 74 (37.6%) 114 (57.9%) 108 (54.0%)

n=172 n=167 n=172 n=167


3 month poststroke
94 (54.7%)* 70 (41.9%) 91 (52.9%)* 71 (42.5%)

n=162 n=155 n=164 n=156


12 month poststroke
88 (54%)* 66 (42.6%) 74 (45.1%) 69 (44.2%)
*p < 0.05
GHQ-28 = Global Health Questionnaire; MI = Motivational Interviewing; UC = Usual Care

Washington University School of Medicine


Program in Occupational Therapy
Motivational Interviewing (Watkins et al., 2007) (Watkins et al., 2011)

•  There was a protective effect of MI on death (p=0.03) at


12 months, suggesting that improving mood could increase
survival post-stroke
•  None of the therapists who participate in this study were
clinical psychologists (although they did receive regular
clinical psychologist supervision) suggesting that MI could
be learned by other healthcare professionals.

Washington University School of Medicine


Program in Occupational Therapy
Transitional Care Program (Wong & Yeung, 2017)

•  Both intervention and control groups received a routine


hospital based physical training programme

•  3 Key Components
1.  The Holistic Care Interventions Component
2.  The Transitional Care Track
3.  The Holistic Care Managers

Washington University School of Medicine


Program in Occupational Therapy
Transitional Care Program (Wong & Yeung, 2017)

•  The Holistic Care Interventions Component


•  Structured using the Omaha System – an assessment-intervention-
evaluation framework
•  Assessment Framework with 4 domains: Environmental,
Psychosocial, Physiological, and health related behaviors
•  Intervention Scheme: surveillance, health teaching and
counselling, treatment and procedures, and case management
•  Stroke Specific Domains: management and prevention of stroke
recurrence, symptoms assessment and management, enhancing
physical function: self-care abilities and exercise, healthy behavior:
adherence to medication and diet, building resilience: connection with
self, family, social life and a Higher Being, and emotion management

Washington University School of Medicine


Program in Occupational Therapy
Transitional Care Program (Wong & Yeung, 2017)

•  The Transitional Care Track


•  Pre-discharge – entrance family meeting
•  Week 1 – home visit on day 2-4, telephone follow-up on day 7
•  Week 2 – home visit on day 2-4, telephone follow-up on day 7
•  Week 3 – home visit on day 2-4, telephone follow-up on day 7
•  Week 4 – home visit on day 2-4, exit family meeting

Washington University School of Medicine


Program in Occupational Therapy
Transitional Care Program (Wong & Yeung, 2017)

•  The Holistic Care Managers (HCM)


•  Recruited nurses who had relevant experience in stroke care and in
the community setting; supported by multidisciplinary team
•  3 day training workshop on the Omaha system, transitional care,
home visits, telephone follow-up and the holistic care intervention
protocols
•  Workshops included theoretical input and training cases

•  OT scope of practice

Washington University School of Medicine


Program in Occupational Therapy
SF-36-HK and WHOQoL-SRPB-HK scores at baseline, 4 weeks, and 8 weeks (Wong and Yeung, 2017)

SF-36-HK MCS WHOQOL-SRPB-HK CES-D-HK Total CES-D-HK Mood

HBPTP
TCP HBPTP TCP
TCP HBPTP TCP HBPTP mean
mean (10th mean (10th mean (10th
mean (SD) mean (SD) mean (SD) mean (SD) (10th and
and 90th) and 90th) and 90th)
90th)

n=54 n=54
n=54 n=54 n=54 n=54 n=54 n=54
4 Weeks
49.9 1
49.2 (1.1) 12.5 (3.1)** 9.8 (2.5) 2 (0-5)** 4 (1.5-8) 2.8 (1-5)
(1.0)** (0-3.5)**
n=54
n=54 n=54 n=54 n=54 n=54 n=54 n=54
8 Weeks
49.9
49.4 (1.4) 12.1 (2.9)** 9.8 (2.7) 2 (0-4)** 4 (0-7) 1 (0-3)** 3 (0-5)
(1.0)**
*p < 0.05; ** p < 0.01
SF-36-HK = Short Form Health Survey-36, Hong Kong version; WHOQOL-SRPB-HK = World Health Organization - Quality of
Life - Spirituality, Religion and Personal Beliefs, Hong Kong Version; CES-D-HK = Center for Epidemiological Studies
Depression Scale, Hong Kong Version; TCP = Transitional Care Programme; HBPTP: Hospital Based Physical Training Program

Washington University School of Medicine


Program in Occupational Therapy
References
•  Lai, S. M., Studenski, S., Richards, L., Perera, S., Reker, D., Rigler, S., & Duncan, P. W. (2006). Therapeutic exercise and depressive symptoms
after stroke. Journal of the American Geriatrics Society, 54(2), 240-247. doi:https://dx.doi.org/10.1111/j.1532-5415.2006.00573.x
•  Man, S. C., Hung, B. H., Ng, R. M., Yu, X. C., Cheung, H., Fung, M. P., . . . Zhang, Z. J. (2014). A pilot controlled trial of a combination of dense
cranial electroacupuncture stimulation and body acupuncture for post-stroke depression. BMC Complementary & Alternative Medicine, 14, 255.
doi:https://dx.doi.org/10.1186/1472-6882-14-255
•  Mitchell, P., Veith, R., Becker, K., Buzaitis, A., Cain, K., Fruin, M., . . . Teri, L. (2009). Brief psychosocial-behavioral intervention with antidepressant
reduces poststroke depression significantly more than usual care with antidepressant: living well with stroke: randomized, controlled trial. Stroke; a
journal of cerebral circulation, 40(9), 3073-3078. Retrieved from http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/144/CN-00720144/
frame.html; http://stroke.ahajournals.org/content/strokeaha/40/9/3073.full.pdf doi:10.1161/STROKEAHA.109.549808
•  Topcuoglu, A., Ordu Gokkaya, N. K., Halil, U., & Karakuş, D. (2015). The effect of upper-extremity aerobic exercise on complex regional pain
syndrome type I: A randomized controlled study on subacute stroke. Topics in stroke rehabilitation, 22(4), 253-261. doi:10.1179/1074935714Z.
0000000025
•  Watkins, C. L., Auton, M. F., Deans, C. F., Dickinson, H. A., Jack, C. I., Lightbody, C. E., . . . Leathley, M. J. (2007). Motivational interviewing early
after acute stroke: a randomized, controlled trial. Stroke, 38(3), 1004-1009. doi:https://dx.doi.org/10.1161/01.STR.0000258114.28006.d7
•  Watkins, C. L., Wathan, J. V., Leathley, M. J., Auton, M. F., Deans, C. F., Dickinson, H. A., . . . Lightbody, C. E. (2011). The 12-month effects of
early motivational interviewing after acute stroke: a randomized controlled trial. Stroke, 42(7), 1956-1961. doi:https://dx.doi.org/10.1161/
STROKEAHA.110.602227
•  Wong, F., & Yeung, S. (2017). Effects of a 4-week transitional care programme for discharged stroke survivors in Hong Kong: a randomised
controlled trial. Health & social care in the community, 23(6), 619-631. Retrieved from http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/
060/CN-01265060/frame.html; http://onlinelibrary.wiley.com/doi/10.1111/hsc.12177/abstract; http://onlinelibrary.wiley.com/store/10.1111/hsc.
12177/asset/hsc12177.pdf?v=1&t=j6z5p5sg&s=78c0344f6064d9351a2becfa293c919a66996362 doi:10.1111/hsc.12177

Washington University School of Medicine


Program in Occupational Therapy

You might also like