RX-10

Enhance Your Jacketed Lab Reactor

Beat Dietrich
August 2015
Content

 Jacketed Lab Reactor (JLR) Challenges

 RX-10 Overview
 Voice of the Customer

1
What is a JLR System?
Stirrer

PAT Probe

Temperature

Jacketed Lab Reactor

2
 Challenges with Traditional Lab Reactors

Inconsistent Manual Parameter Lost or Missing Data Manual

Controls Control Failing to Document Documentation
Means time- Scientists must be in Leads to Repeat and Reporting
consuming task of lab to change process Experiments Time Consuming
relearning controls parameters and Error Prone

Lack of integration Inefficient use of Increase waste of Bottlenecks post

Increases risk of resources and materials and time experiment delay
inconsistent results limited ability to run timely decisions
safe overnight
experiments

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 Solution Overview with RX-10

One Simple, Unattended 24/7 100 % Data Powerful

Standard Interface Capture Reporting

An integrated Sequences of Record complete and Quickly prepare

controller for all automated parameter accurate process data reports for accurate
process chemistry controls means for improved history and
equipment increases experiments can be experiment effective
accessibility and run safely overnight documentation and communicaiton
consistency process knowledge

4
Content

 Jacketed Lab Reactor (JLR) Challenges

 RX-10 Overview
 Voice of the Customer

5
RX-10 Overview

Sensor Port Third party sensors

such as:
• Reflux temperature
• Mass flow meter
• Pressure sensors

RS232
Network
iControl / iC DC
PC-based recipe
Tr control and data
analysis with
PAT integration

Accessories
• Automated Dosing
• Additional sensors
• Sampling

Existing Jacketed RX-10 Base Unit Peripherals

Lab Reactor Touchscreen Operation

6
 RX-10 at a Glance

SmartConnect sensor port USB ports

Plug & play of Pt100, Data Export
voltage and current sensors Firmware Upgrades

Ethernet (Network)
iControl / iC Data Center
CAN accessories
Plug & play connectivity
Touchscreen port
to DU-SP50, EasySampler,
1 m or 3 m cable length
ECB, etc.

Thermostat/Stirrer
Easy-to-use touchscreen RS232 port, plug & play
Basic functions learned recognition of equipment
within 60 seconds

Safety relay
Acoustic or visual alerts

Emergency button
To trigger emergency
program

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SmartConnect™ Cable
SmartConnect Cable
- Smart chip technology automatically recognizes
standard laboratory instrumentation for
immediate control and data collection
No need for added adaptors or specialized setup
time/cost
Moving instrumentation from one vessel to another
is fast and easy
- Connects to:
PT100 (Temperature)
Pressure sensors, Mass Flow Meters
Any Other Analog Sensor with Voltage or
Current Output
RX-10: Technical Specification
Thermostats
Stirrers
Temperature Range
Volume range / Reactors
SmartConnectTM Port
(plug & play)
Connectivity and data transfer
Supported languages
Safety features
Dimensions, W x D x H
Weight
Huber, Julabo – all models with RS232 port.
IKA, Heidolph, J-KEM – all models with RS232 port
Full range supported by Huber or Julabo thermostats
(-120 °C – 425 °C)
Choose what is best for your application.
There are no volume or reactor limits given by RX-10.
Pt100 4 wires (RTD)
Voltage -10 V to +10 V
Current 0 to 20mA
Ethernet: Communication to PC
(iControl/iC Data Center)
CAN: Interface for peripherals (ECB, DU-SP50, EasySampler)
USB: Data Export to USB stick
English, German, French, Spanish, Japanese, Chinese
- Emergency button for immediate execution
of emergency program
- Emergency relay to connect audible or visual alert
70 mm x 152 mm x 215 mm (2.75” x 5.98” x 8.46”)
2,88 kg, including touchscreen
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 RX-10: Delivery Scope
30208790: 30217050:
RX-10 with RX-10 with
1m touch- 3m touch-
screen screen
cable cable
1 RX-10 main unit 1 1
2 Touchscreen 7’’
1
(1m cable)
Touchscreen 7’’
3 1
(3m cable)
4 Power Supply 1 1
5 Lab Bar Holder 1 1
Thermostat/Stirrer
6 1 1
RS232 cables
USB memory stick
7 1 1
2GB
8 iControl DVD 1 1
9 iControl Office License 1 1
RX-10 Quick Start
10 1 1
Guide
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Synthesis and Process Development Tools

EasyMax and OptiMax are Turn Key Development Workstations

 All-in-one System / Minimal Footprint
 Reactors are Easy to Change and Easy to Clean
 No Need For External Thermostat
 Ready-to-Go Reactor Setups
 Fast And Stable Temperature Control
 Easily Upgrade To Calorimeter

EasyMax 102
1 ml – 400 ml EasyMax 402
100 ml – 400 ml OptiMax
250 ml – 1000 ml

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Feature Comparison
EasyMax /
# Feature Standalone JLR RX-10 RC1e
OptiMax
1 All-in-one system / minimal footprint    
2 Reactor easy to change/clean    
3 No need for external thermostat    
Ready to go reactor setups
4    
for distillations, pressure, ..
5 Touchscreen to control ALL process params    
6 iControl    *
7 iC Data Center    
8 PAT data integration    
9 UCB Universal Control Box (RS485) – PC only    
10 EasySampler integration    
11 ECB Easy Control Box (CAN plug'n'play)    
12 DU-SP50 Dosing Unit (syringe pump)    
13 Upgradable to calorimeter    
14 RTCal    
15 Adiabatic mode    
16 Real Tj measurement not T bath of chiller - -  
17 Tr-Tj control for distillations / reflux    
18 Non-linear ramps for crystallizations    
19 Fast and stable T control    
20 One-click report    
* = iControl recipe exchange possible between RX-10, EM and OM but not with RC1e. iControl for RC1e is a different application.
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RX-10 Data Handling

Touchscreen Data Management PC Software

Easy to use control Capture and archive Advanced control, may be
in front of the reactor data at a remote location

File transfer and Automated data Advanced

basic evaluation capture, preparation online/offline
after experiment and sharing evaluation
completion

USB / Ethernet iC Data Center iControl

Touchscreen
Homescreen – Learn in 60s Pre-programming of Up to 6 Steps

Programming a T Ramp Live Trend Graph

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iControl – Powerful PC Software

 Easy-to-Use
 Advanced Task Programming
 Re-run of Experiments
 Comprehensive Trend Graph
 Intuitive Data Processing
 Powerful Reporting Function
 Seamless Integration with
METTLER TOLEDO Analytical
Tools

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iControl – One Software for all Volumes

Copy Recipes Between Reactors;

Easily Overlay and Compare Data

Small Volume Medium Volume Large Volume

EasyMax 102 EasyMax 402 OptiMax RX-10

1ml – 400ml 100ml – 400ml 250ml – 1000ml >1000ml

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 iControl – Remote Control from PC
Up to 4 Connected Units – RX-10, EasyMax or OptiMax

Drag'n'Drop Recipe Designer

Drag'n'Drop

 iControl Introduction Video on YouTube (4min)

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RX-10 Laboratory: iC Data Center

Automated Data
Collection with iC
Data Center
- Automatically
Capture, Prepare
and Share data
from variety of
instruments and
transform it into
valuable process
data
- iControl is not
required – data
capture without
the need for a PC
in the lab!
Content

 Jacketed Lab Reactor (JLR) Challenges

 RX-10 Overview
 Voice of the Customer

20
Voice of the Customer
Since we installed the RX-10, our jacketed lab reactors are used much more
frequently. It is now easy and intuitive to program, manage and store data, and
interpret experimental results. Safety limits on reactors reduce risk for the whole
lab… In short, RX-10 makes our jobs easier and safer.
Andy Huygaerts, Janssen Pharma, Belgium

The RX-10 is a universal Jacket Lab Reactor (JLR) control unit that works truly
plug’n play. My favorite function: It enables basic lab operations such as
temperature, agitation and dosing control as well as data capturing on existing
equipment. A simple entry door into the world of lab automation!
Gregor Schock (Grünenthal, Germany)

The RX-10 unit is a versatile solution to optimize scale-up processes. In our

Lab, it has closed the gap between EasyMax/OptiMax Synthesis Workstations
and multi-liter JLR vessels. As main benefits, it provides a consistent lab
workflow to the user and gives documentation of experiments along the whole
scale-up workflow.
Dr. Carsten Griebel (Grünenthal, Germany)

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 Questions?

One Simple, Unattended 24/7 100 % Data Powerful

Standard Interface Capture Reporting

www.mt.com/RX-10

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