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DAFTAR PUSTAKA

1. Strausbaugh LJ. Emerging health care-associated infections in the geriatric


population. Emerg Infect Dis [Internet].2001;7(2):268–71. Available from:
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2631705&tool=pmc
entrez&rendertype=abstract.

2. Chatta GS, Andrews RG, Rodger E, Schrag M, Hammond WP, Dale DC.
Hematopoietic progenitors and aging: alterations in granulocyticprecursors and
responsiveness to recombinant humanG-CSF, GM-CSF, and IL-3. J Gerontol
[Internet] ed.1993;48(5):M207–M212. Available from:
http://www.ncbi.nlm.nih.gov/pubmed/7690056.

3. Fortin CF, McDonald PP, Lesur O, Fulop Jr. T. Aging and neutrophils:there is
still much to do. Rejuvenation Res [Internet].2008/10/14 ed. 2008;11(5):873–
882. Available from: http://www.ncbi.nlm.nih.gov/pubmed/18847379

4. Mahbub S, Brubaker AL, Kovacs EJ. Aging of the innate immune system: an
update. Curr Immunol Rev [Internet]. 2011/04/05 ed. 2011;7(1):104–115.
Available from: http://www.ncbi.nlm.nih.gov/pubmed/21461315.

5. MacGregor RR, Shalit M. Neutrophil function in healthy elderly subjects. J


Gerontol [Internet] 1990/03/01 ed. 1990;45(2):M55–M60. Available from:
http://www.ncbi.nlm.nih.gov/pubmed/1968921.

6. Biasi D, Carletto A, Dell’Agnola C, Caramaschi P, Montesanti F, Zavateri G, et


al. Neutrophil migration, oxidative metabolism, and adhesion in elderly and
young subjects. Inflammation [Internet]. 1996/12/01 ed. 1996;20(6):673–681.
Available from: http://www.ncbi.nlm.nih.gov/pubmed/8979154

7. Niwa Y, Kasama T, Miyachi Y, Kanoh T. Neutrophil chemotaxis, phagocytosis


and parameters of reactive oxygen species in human aging: cross-sectional and
longitudinal studies. Life Sci [Internet]1989/01/01 ed. 1989;44(22):1655–1664.
Available from: http://www.ncbi.nlm.nih.gov/pubmed/2733545

8. Antonaci S, Jirillo E, Ventura MT, Garofalo AR, Bonomo L. Non-specific


immunity in aging: deficiency of monocyte and polymorphonuclearcell-
mediated functions. Mech Ageing Dev [Internet].1984/03/01 ed.
1984;24(3):367–375. Available from:
http://www.ncbi.nlm.nih.gov/pubmed/6717097.
9. Fulop T, Larbi A, Douziech N, Fortin C, Guerard KP, Lesur O, et al. Signal
transduction and functional changes in neutrophils with aging. Aging Cell [Internet].
2004/07/23 ed. 2004;3(4):217–226.
Available from: http://www.ncbi.nlm.nih.gov/pubmed/15268755.

10. Brubaker AL, Rendon JL, Ramirez L, Choudhry MA, Kovacs


EJ. Reduced neutrophil chemotaxis and infiltration contributes to
delayed resolution of cutaneous wound infection with advanced
age. J Immunol. United States. 2013;190(4):1746–57

11. Verschoor CP, Puchta A, Bowdish DM. The macrophage. Methods


Mol Biol [Internet]. 2012/01/21 ed. 2012;844:139–156. Available
from: http://www.ncbi.nlm.nih.gov/pubmed/22262440.

12. Ogawa T, Kitagawa M, Hirokawa K. Age-related changes of


human bone marrow: a histometric estimation of proliferative
cells, apoptotic cells, T cells, B cells and macrophages. Mech
Ageing Dev [Internet]. 2000/08/26 ed. 2000;117(1–3):57–68.
Available from: http://www.ncbi.nlm.nih.gov/pubmed/10958923.

13. Zissel G, Schlaak M, Muller-Quernheim J. Age-related decrease


in accessory cell function of human alveolar macrophages.
J Investig Med [Internet]. 1999/03/11 ed. 1999;47(1):51–6.
Available from: http://www.ncbi.nlm.nih.gov/pubmed/10071481.

14. Weiskopf D, Weinberger B, Grubeck-Loebenstein B. The aging of


the immune system. Transpl Int [Internet]. 2009/07/25 ed.
2009;22(11):1041–50. Available from: http://www.ncbi.nlm.nih.
gov/pubmed/19624493.

15. Plowden J, Renshaw-Hoelscher M, Engleman C, Katz J, Sambhara


S. Innate immunity in aging: impact on macrophage function.
Aging Cell [Internet]. 2004/07/23 ed. 2004;3(4):161–7. Available
from: http://www.ncbi.nlm.nih.gov/pubmed/15268749.

16. Plackett TP, Boehmer ED, Faunce DE, Kovacs EJ. Aging and
innate immune cells. J Leukoc Biol [Internet]. 2004/03/25 ed.
2004;76(2):291–9. Available from: http://www.ncbi.nlm.nih.gov/
pubmed/15039467

17. Borrego F, Alonso MC, Galiani MD, Carracedo J, Ramirez R,


Ostos B, et al. NK phenotypic markers and IL2 response in NK
cells from elderly people. Exp Gerontol [Internet]. 1999/06/11 ed.
1999;34(2):253–65. Available from: http://www.ncbi.nlm.nih.
gov/pubmed/10363791.
18. Rukavina D, Laskarin G, Rubesa G, Strbo N, Bedenicki I,
Manestar D, et al. Age-related decline of perforin expression in
human cytotoxic T lymphocytes and natural killer cells. Blood
[Internet]. 1998/09/25 ed. 1998;92(7):2410–20. Available f rom:
http://www.ncbi.nlm.nih.gov/pubmed/9746781.

19. Hazeldine J, Hampson P, Lord JM. Reduced release and binding


of perforin at the immunological synapse underlies the age-related
decline in Natural Killer cell cytotoxicity. Aging Cell [Internet].
2012/05/31 ed. 2012; Available from: http://www.ncbi.nlm.nih.
gov/pubmed/22642232.

20. Lutz CT, Moore MB, Bradley S, Shelton BJ, Lutgendorf SK.
Reciprocal age related change in natural killer cell receptors for
MHC class I. Mech Ageing Dev. 2005;126(6–7):722–31.

21. Ogata K, An E, Shioi Y, Nakamura K, Luo S, Yokose N, et al.


Association between natural killer cell activity and infection in
immunologically normal elderly people. Clin Exp Immunol
[Internet]. 2001/07/27 ed. 2001;124(3):392–7. Available from:
http://www.ncbi.nlm.nih.gov/pubmed/11472399.

22. Reise Sousa C. Dendritic cells in a mature age. Nat Rev Immunol
[Internet]. 2006/05/13 ed. 2006;6(6):476–83. Available from:
http://www.ncbi.nlm.nih.gov/pubmed/16691244.

23. Serbina N V, Salazar-Mather TP, Biron CA, Kuziel WA, Pamer


EG. TNF/iNOS-producing dendritic cells mediate innate immune
defense against bacterial infection. Immunity [Internet].
2003/07/23 ed. 2003;19(1):59–70. Available from: http://www.
ncbi.nlm.nih.gov/pubmed/12871639.

24. Cools N, Ponsaerts P, Van Tendeloo VF, Berneman ZN. Balancing


between immunity and tolerance: an interplay between dendritic
cells, regulatory T cells, and effector T cells. J Leukoc Biol
[Internet]. 2007/08/23 ed. 2007;82(6):1365–74. Available from:
http://www.ncbi.nlm.nih.gov/pubmed/17711977.

25. Nagy L, Szanto A, Szatmari I, Szeles L. Nuclear hormone receptors


enable macrophages and dendritic cells to sense their lipid environment and shape their
immune response. Physiol Rev
[Internet]. 2012/04/27 ed. 2012;92(2):739–89. Available from:
http://www.ncbi.nlm.nih.gov/pubmed/22535896.

26. Agrawal A, Agrawal S, Cao JN, Su H, Osann K, Gupta S. Altered


innate immune functioning of dendritic cells in elderly humans: a
role of phosphoinositide 3-kinase-signaling pathway. J Immunol
[Internet]. 2007/05/22 ed. 2007;178(11):6912–22. Available
from: http://www.ncbi.nlm.nih.gov/pubmed/17513740.

27. Agrawal A, Agrawal S, Gupta S. Dendritic cells in human aging.


Exp Gerontol [Internet]. 2006/12/22 ed. 2007;42(5):421–6.
Available from: http://www.ncbi.nlm.nih.gov/pubmed/17182207.

28. Fadok VA, Bratton DL, Konowal A, Freed PW, Westcott JY,
Henson PM. Macrophages that have ingested apoptotic cells
in vitro inhibit proinflammatory cytokine production through
autocrine/paracrine mechanisms involving TGF-beta, PGE2, and
PAF. J Clin Invest [Internet]. 1998/03/21 ed. 1998;101(4):890–8.
Available from: http://www.ncbi.nlm.nih.gov/pubmed/9466984.

29. Singer AL, Koretzky GA. Control of T cell function by positive


and negative regulators. Science (80- ) [Internet]. 2002/06/01 ed.
2002;296(5573):1639–40. Available from: http://www.ncbi.nlm.
nih.gov/pubmed/12040176.

30. Sprent J, Tough DF. T cell death and memory. Science (80- )
[Internet]. 2001/07/14 ed. 2001;293(5528):245–8. Available
from: http://www.ncbi.nlm.nih.gov/pubmed/11452113.

31. Fulop T, Larbi A, Wikby A, Mocchegiani E, Hirokawa K, Pawelec


G. Dysregulation of T-cell function in the elderly : scientific basis
and clinical implications. Drugs Aging. 2005;22(7):589–603.

32. Kendall MD, Johnson HR, Singh J. The weight of the human thymus
gland at necropsy. J Anat [Internet]. 1980/10/01 ed.
1980;131(Pt 3):483–97. Available from: http://www.ncbi.nlm.nih.
gov/pubmed/7216915.

33. Hakim FT, Memon SA, Cepeda R, Jones EC, Chow CK, Kasten-Sportes
C, et al. Age-dependent incidence, time course, and consequences
of thymic renewal in adults. J Clin Invest [Internet].
2005/03/19 ed. 2005;115(4):930–9. Available from: http://www.
ncbi.nlm.nih.gov/pubmed/15776111

34. Goronzy JJ, Lee WW, Weyand CM. Aging and T-cell diversity.
Exp Gerontol [Internet]. 2007/01/16 ed. 2007;42(5):400–6.
Available from: http://www.ncbi.nlm.nih.gov/pubmed/17218073

35. Malaguarnera L, Ferlito L, Imbesi RM, Gulizia GS, Di Mauro S,


Maugeri D, et al. Immunosenescence: a review. Arch Gerontol
Geriatr [Internet]. 2001/03/17 ed. 2001;32(1):1–14. Available
from: http://www.ncbi.nlm.nih.gov/pubmed/11251234

36. Goronzy JJ, Weyand CM. T cell development and receptor diversity
during aging. Curr Opin Immunol [Internet]. 2005/08/16 ed.
2005;17(5):468–75. Available from: http://www.ncbi.nlm.nih.
gov/pubmed/16098723.

37. Schwab R, Szabo P, Manavalan JS, Weksler ME, Posnett DN,


Pannetier C, et al. Expanded CD4+ and CD8+ T cell clones in
elderly humans. J Immunol [Internet]. 1997/05/01 ed.
1997;158(9):4493–9. Available from: http://www.ncbi.nlm.nih.
gov/pubmed/9127016

38. Naylor K, Li G, Vallejo AN, Lee WW, Koetz K, Bryl E, et al. The
influence of age on T cell generation and TCR diversity. J Immunol
[Internet]. 2005/05/21 ed. 2005;174(11):7446–52. Available
from: http://www.ncbi.nlm.nih.gov/pubmed/15905594.

39. Cooper MD, Alder MN. The evolution of adaptive immune systems.
Cell [Internet]. 2006/02/25 ed. 2006;124(4):815–22.
Available from: http://www.ncbi.nlm.nih.gov/pubmed/16497590

40. McHeyzer-Williams M, Okitsu S, Wang N, McHeyzer-Williams


L. Molecular programming of B cell memory. Nat Rev Immunol
[Internet]. 2011/12/14 ed. 2012;12(1):24–34. Available from:
http://www.ncbi.nlm.nih.gov/pubmed/22158414.

41. Frasca D, Blomberg BB. Aging affects human B cell responses.


J Clin Immunol [Internet]. 2011/02/15 ed. 2011;31(3):430–5.
Available from: http://www.ncbi.nlm.nih.gov/pubmed/21318330.

42. Chong Y, Ikematsu H, Yamaji K, Nishimura M, Nabeshima S,


Kashiwagi S, et al. CD27(+) (memory) B cell decrease and
apoptosis-resistant
CD27(−) (naive) B cell increase in aged
humans: implications for age-related peripheral B cell developmental
disturbances. Int Immunol [Internet]. 2005/02/23 ed.
2005;17(4):383–90. Available from: http://www.ncbi.nlm.nih.
gov/pubmed/15724062.
43. Frasca D, Diaz A, Romero M, Landin AM, Blomberg BB. Age
effects on B cells and humoral immunity in humans. Ageing Res
Rev [Internet]. 2010/08/24 ed. 2011;10(3):330–5. Available from:
http://www.ncbi.nlm.nih.gov/pubmed/20728581.
44. Aydar Y, Balogh P, Tew JG, Szakal AK. Age-related depression of
FDC accessory functions and CD21 ligand-mediated repair of co-stimulation.
Eur J Immunol [Internet]. 2002/10/02 ed.
2002;32(10):2817–26. Available from: http://www.ncbi.nlm.nih.
gov/pubmed/12355434.
45. Colonna-Romano G, Bulati M, Aquino A, Scialabba G, Candore
G, Lio D, et al. B cells in the aged: CD27, CD5, and CD40 expression.
Mech Ageing Dev [Internet]. 2003/04/26 ed.
2003;124(4):389–93. Available from: http://www.ncbi.nlm.nih.
gov/pubmed/12714244.
46. Kogut I, Scholz JL, Cancro MP, Cambier JC. B cell maintenance
and function in aging. Semin Immunol [Internet]. 2012/05/09 ed.
2012;24(5):342–9. Available from: http://www.ncbi.nlm.nih.gov/
pubmed/22560930.
47. Franceschi C, Bonafe M, Valensin S, Olivieri F, De Luca M,
Ottaviani E, et al. Inflamm-aging. An evolutionary perspective on
immunosenescence. Ann N Y Acad Sci [Internet]. 2000/07/27 ed.
2000;908:244–54. Available from: http://www.ncbi.nlm.nih.gov/
pubmed/10911963.
48. Alvarez-Rodriguez L, Lopez-Hoyos M, Munoz-Cacho P,
Martinez-Taboada VM. Aging is associated with circulating cytokine
dysregulation. Cell Immunol [Internet]. 2012/02/10 ed.
2012;273(2):124–32. Available from: http://www.ncbi.nlm.nih.
gov/pubmed/22316526.
49. Forsey RJ, Thompson JM, Ernerudh J, Hurst TL, Strindhall J,
Johansson B, et al. Plasma cytokine profiles in elderly humans.
Mech Ageing Dev [Internet]. 2003/04/26 ed. 2003;124(4):487–93.
Available from: http://www.ncbi.nlm.nih.gov/pubmed/12714257.
50. O’Mahony L, Holland J, Jackson J, Feighery C, Hennessy TP,
Mealy K. Quantitative intracellular cytokine measurement: age-related
changes in proinflammatory cytokine production. Clin Exp
Immunol [Internet]. 1998/08/26 ed. 1998;113(2):213–9. Available
from: http://www.ncbi.nlm.nih.gov/pubmed/9717970.
51. Roubenoff R, Harris TB, Abad LW, Wilson PW, Dallal GE,
Dinarello CA. Monocyte cytokine production in an elderly population:
effect of age and inflammation. J Gerontol A Biol Sci Med
Sci [Internet]. 1998/02/19 ed. 1998;53(1):M20–6. Available from:
http://www.ncbi.nlm.nih.gov/pubmed/9467429.
52. Jean-Philippe C, Desprez P-Y, Krtolica A, Campisi J. The
senescence-associated
secretory phenotype: the dark side of tumor
suppression. Annu Rev Pathol. 2010;5:99–118.
53. Franceschi C, Campisi J. Chronic inflammation (Inflammaging)
and its potential contribution to age-associated diseases. J Gerontol
Ser A Biol Sci Med Sci. 2014;69:S4–9.
54. Cannizzo ES, Clement CC, Sahu R, Follo C, Santambrogio
L. Oxidative stress, inflamm-aging and immunosenescence.
J Proteomics. 2011;74(11):2313–23. Available from: http://linkinghub.
elsevier.com/retrieve/pii/S1874391911002600.
55. Reuben DB, Cheh AI, Harris TB, Ferrucci L, Rowe JW, Tracy RP,
et al. Peripheral blood markers of inflammation predict mortality
and functional decline in high-functioning community-dwelling
older persons. J Am Geriatr Soc [Internet]. 2002/05/02 ed.
2002;50(4):638–44. Available from: http://www.ncbi.nlm.nih.
gov/pubmed/11982663

56. Ferrucci L, Penninx BW, Volpato S, Harris TB, Bandeen-Roche


K, Balfour J, et al. Change in muscle strength explains accelerated
decline of physical function in older women with high interleukin-
6
serum levels. J Am Geriatr Soc [Internet]. 2002/12/11 ed.
2002;50(12):1947–54. Available from: http://www.ncbi.nlm.nih.
gov/pubmed/12473005.
57. Roubenoff R, Parise H, Payette HA, Abad LW, D’Agostino R,
Jacques PF, et al. Cytokines, insulin-like growth factor 1, sarcopenia,
and mortality in very old community-dwelling men and
women: the Framingham Heart Study. Am J Med [Internet].
2003/10/18 ed. 2003;115(6):429–35. Available from: http://
www.
ncbi.nlm.nih.gov/pubmed/14563498.
58. Ferrucci L, Harris TB, Guralnik JM, Tracy RP, Corti MC, Cohen
HJ, et al. Serum IL-6 level and the development of disability in
older persons. J Am Geriatr Soc [Internet]. 1999/06/12 ed.
1999;47(6):639–46. Available from: http://www.ncbi.nlm.nih.
gov/pubmed/10366160.
59. Giunta B, Fernandez F, Nikolic WV, Obregon D, Rrapo E, Town
T, et al. Inflammaging as a prodrome to Alzheimer’s disease.
J Neuroinflammation. England. 2008;5:51.
60. Gallenga CE, Parmeggiani F, Costagliola C, Sebastiani A,
Gallenga PE. Inflammaging: should this term be suitable for age
related macular degeneration too? Inflamm Res. Switzerland.
2014;63(2):105–7.
61. Lencel P, Magne D. Inflammaging: the driving force in osteoporosis?
Med Hypotheses. United States. 2011;76(3):317–21.
62. Greene MA, Loeser RF. Aging-related inflammation in osteoarthritis.
Osteoarthritis Cartilage. England. 2015;23(11):1966–71.
63. National Center for Health S. Health, United States. Heal United
States, 2014 With Spec Featur Adults Aged 55–64. 2015.
64. Singanayagam A, Joshi P V, Mallia P, Johnston SL. Viruses exacerbating
chronic pulmonary disease: the role of immune modulation.
BMC Med [Internet]. 2012/03/17 ed. 2012;10:27. Available
from: http://www.ncbi.nlm.nih.gov/pubmed/22420941.
65. Bochicchio GV. Nosocomial infections in elderly trauma patients:
incidence and microbiology. Infect Med. 2002;19(11):512–6.
66. Agostini P, Cieslik H, Rathinam S, Bishay E, Kalkat MS, Rajesh
PB, et al. Postoperative pulmonary complications following thoracic
surgery: are there any modifiable risk factors? Thorax
[Internet]. 2010/09/02 ed. 2010;65(9):815–8. Available from:
http://www.ncbi.nlm.nih.gov/pubmed/20805178.
67. Sliedrecht A, den Elzen WP, Verheij TJ, Westendorp RG,
Gussekloo J. Incidence and predictive factors of lower respiratory
tract infections among the very elderly in the general population.
The Leiden 85-plus Study. Thorax [Internet]. 2008/04/05 ed.
2008;63(9):817–22. Available from: http://www.ncbi.nlm.nih.
gov/pubmed/18388206.
68. Jansen HM, Sachs AP, van Alphen L. Predisposing conditions to
bacterial infections in chronic obstructive pulmonary disease. Am
J Respir Crit Care Med [Internet]. 1995/06/01 ed.
1995;151(6):2073–80. Available from: http://www.ncbi.nlm.nih.
gov/pubmed/7767560.
69. Herrero FS, Olivas JB. Microbiology and risk factors for
community-acquired
pneumonia. Semin Respir Crit Care Med
[Internet]. 2012/06/22 ed. 2012;33(3):220–31. Available from:
http://www.ncbi.nlm.nih.gov/pubmed/22718208.
70. Torres A, Dorca J, Zalacain R, Bello S, El-Ebiary M, Molinos L,
et al. Community-acquired pneumonia in chronic obstructive pulmonary
disease: a Spanish multicenter study. Am J Respir Crit
Care Med [Internet]. 1996/11/01 ed. 1996;154(5):1456–61.
Available from: http://www.ncbi.nlm.nih.gov/pubmed/8912764.
71. Restrepo MI, Mortensen EM, Pugh JA, Anzueto A. COPD is associated
with increased mortality in patients with community-acquired
pneumonia. Eur Respir J [Internet]. 2006/04/14 ed.
2006;28(2):346–51. Available from: http://www.ncbi.nlm.nih.

72. Hruska LA, Smith JM, Hendy MP, Fritz VL, McAdams
S. Continuous insulin infusion reduces infectious complications in
diabetics following coronary surgery. J Card Surg [Internet].
2005/09/13 ed. 2005;20(5):403–7. Available from: http://www.
ncbi.nlm.nih.gov/pubmed/16153268.
73. Shah BR, Hux JE. Quantifying the risk of infectious diseases for
people with diabetes. Diabetes Care [Internet]. 2003/01/28 ed.
2003;26(2):510–3. Available from: http://www.ncbi.nlm.nih.gov/
pubmed/12547890.
74. Shilling AM, Raphael J. Diabetes, hyperglycemia, and infections.
Best Pr Res Clin Anaesthesiol [Internet]. 2008/10/04 ed.
2008;22(3):519–35. Available from: http://www.ncbi.nlm.nih.
gov/pubmed/18831301.
75. Fietsam Jr. R, Bassett J, Glover JL. Complications of coronary
artery surgery in diabetic patients. Am Surg [Internet]. 1991/09/11
ed. 1991;57(9):551–7. Available from: http://www.ncbi.nlm.nih.
gov/pubmed/1928997.
76. Angarita FA, Acuna SA, Torregrosa L, Tawil M, Escallon J, Ruiz
A. Perioperative variables associated with surgical site infection in
breast cancer surgery. J Hosp Infect [Internet]. 2011/11/08 ed.
2011;79(4):328–32. Available from: http://www.ncbi.nlm.nih.
gov/pubmed/22054593.
77. Latham R, Lancaster AD, Covington JF, Pirolo JS, Thomas Jr.
CS. The association of diabetes and glucose control with surgical-site
infections among cardiothoracic surgery patients. Infect Control
Hosp Epidemiol [Internet]. 2002/01/05 ed. 2001;22(10):607–12.
Available from: http://www.ncbi.nlm.nih.gov/pubmed/11776345.
78. Investigators N-SS, Finfer S, Chittock DR, Su SY, Blair D, Foster
D, et al. Intensive versus conventional glucose control in critically
ill patients. N Engl J Med [Internet]. 2009/03/26 ed.
2009;360(13):1283–97. Available from: http://www.ncbi.nlm.nih.
gov/pubmed/19318384.
79. Stegenga ME, Vincent JL, Vail GM, Xie J, Haney DJ, Williams
MD, et al. Diabetes does not alter mortality or hemostatic and
inflammatory responses in patients with severe sepsis. Crit Care
Med [Internet]. 2009/10/24 ed. 2010;38(2):539–45. Available
from: http://www.ncbi.nlm.nih.gov/pubmed/19851093.
80. Muller LM, Gorter KJ, Hak E, Goudzwaard WL, Schellevis FG,
Hoepelman AI, et al. Increased risk of common infections in
patients with type 1 and type 2 diabetes mellitus. Clin Infect Dis
[Internet]. 2005/07/12 ed. 2005;41(3):281–8. Available from:
http://www.ncbi.nlm.nih.gov/pubmed/16007521.
81. Dooley KE, Chaisson RE. Tuberculosis and diabetes mellitus:
convergence of two epidemics. Lancet Infect Dis [Internet].
2009/11/21 ed. 2009;9(12):737–46. Available from: http://www.
ncbi.nlm.nih.gov/pubmed/19926034.
82. Ramos M, Khalpey Z, Lipsitz S, Steinberg J, Panizales MT,
Zinner M, et al. Relationship of perioperative hyperglycemia and
postoperative infections in patients who undergo general and vascular
surgery. Ann Surg [Internet]. 2008/10/22 ed.
2008;248(4):585–91. Available from: http://www.ncbi.nlm.nih.
gov/pubmed/18936571.
83. Ata A, Lee J, Bestle SL, Desemone J, Stain SC. Postoperative
hyperglycemia and surgical site infection in general surgery
patients. Arch Surg [Internet]. 2010/09/22 ed. 2010;145(9):858–64.
Available from: http://www.ncbi.nlm.nih.gov/pubmed/20855756.
84. Furnary AP, Zerr KJ, Grunkemeier GL, Starr A. Continuous intravenous
insulin infusion reduces the incidence of deep sternal
wound infection in diabetic patients after cardiac surgical procedures.
Ann Thorac Surg [Internet]. 1999/04/10 ed. 1999;67(2):352.
Available from: http://www.ncbi.nlm.nih.gov/pubmed/10197653.
85. Golden SH, Peart-Vigilance C, Kao WH, Brancati
FL. Perioperative glycemic control and the risk of infectious complications
in a cohort of adults with diabetes. Diabetes Care
[Internet]. 1999/09/10 ed. 1999;22(9):1408–14. Available from:
http://www.ncbi.nlm.nih.gov/pubmed/10480501.

86. Zerr KJ, Furnary AP, Grunkemeier GL, Bookin S, Kanhere V,


Starr A. Glucose control lowers the risk of wound infection in diabetics
after open heart operations. Ann Thorac Surg [Internet].
1997/02/01 ed. 1997;63(2):356–61. Available from: http://www.
ncbi.nlm.nih.gov/pubmed/9033300.
87. Pomposelli JJ, Baxter 3rd JK, Babineau TJ, Pomfret EA, Driscoll
DF, Forse RA, et al. Early postoperative glucose control predicts
nosocomial infection rate in diabetic patients. JPEN J Parenter
Enter Nutr [Internet]. 1998/04/07 ed. 1998;22(2):77–81. Available
from: http://www.ncbi.nlm.nih.gov/pubmed/9527963.
88. Koh GC, Peacock SJ, van der Poll T, Wiersinga WJ. The impact of
diabetes on the pathogenesis of sepsis. Eur J Clin Microbiol Infect
Dis [Internet]. 2011/08/02 ed. 2012;31(4):379–88. Available
from: http://www.ncbi.nlm.nih.gov/pubmed/21805196.
89. van Oss CJ, Border JR. Influence of intermittent hyperglycemic
glucose levels on the phagocytosis of microorganisms by human
granulocytes in vitro. Immunol Commun [Internet]. 1978/01/01
ed. 1978;7(6):669–76. Available from: http://www.ncbi.nlm.nih.
gov/pubmed/369990.
90. Perner A, Nielsen SE, Rask-Madsen J. High glucose impairs
superoxide production from isolated blood neutrophils. Intensive
Care Med [Internet]. 2003/01/29 ed. 2003;29(4):642–5. Available
from: http://www.ncbi.nlm.nih.gov/pubmed/12552364.
91. Andersen B, Goldsmith GH, Spagnuolo PJ. Neutrophil adhesive
dysfunction in diabetes mellitus; the role of cellular and plasma factors.
J Lab Clin Med [Internet]. 1988/03/01 ed. 1988;111(3):275–
85. Available from: http://www.ncbi.nlm.nih.gov/pubmed/3343542.
92. Delamaire M, Maugendre D, Moreno M, Le Goff MC, Allannic
H, Genetet B. Impaired leucocyte functions in diabetic patients.
Diabet Med [Internet]. 1997/01/01 ed. 1997;14(1):29–34.
Available from: http://www.ncbi.nlm.nih.gov/pubmed/9017350.
93. Liberatore Jr. RR, Barbosa SF, Alkimin MG, Bellinati-Pires R,
Florido MP, Isaac L, et al. Is immunity in diabetic patients influencing
the susceptibility to infections? Immunoglobulins, complement
and phagocytic function in children and adolescents with
type 1 diabetes mellitus. Pediatr Diabetes [Internet]. 2006/01/05
ed. 2005;6(4):206–12. Available from: http://www.ncbi.nlm.nih.
gov/pubmed/16390389.
94. Farid NR, Anderson J. Immunoglobulins and complement in diabetes
mellitus. Lancet [Internet]. 1973/07/14 ed. 1973;2(7820):92.
Available from: http://www.ncbi.nlm.nih.gov/pubmed/4123636.
95. Bouter KP, Diepersloot RJ, Wismans PJ, Gmelig Meyling FH,
Hoekstra JB, Heijtink RA, et al. Humoral immune response to a
yeast-derived hepatitis B vaccine in patients with type 1 diabetes
mellitus. Diabet Med [Internet]. 1992/01/01 ed. 1992;9(1):66–9.
Available from: http://www.ncbi.nlm.nih.gov/pubmed/1532355.
96. Pozzilli P, Arduini P, Visalli N, Sutherland J, Pezzella M, Galli C,
et al. Reduced protection against hepatitis B virus following vaccination
in patients with type 1 (insulin-dependent) diabetes.
Diabetologia [Internet]. 1987/10/01 ed. 1987;30(10):817–9.
Available from: http://www.ncbi.nlm.nih.gov/pubmed/2962892.
97. Ficicioglu C, Mikla S, Midilli K, Aydin A, Cam H, Ergin
S. Reduced immune response to hepatitis B vaccine in children
with insulin dependent diabetes. Acta Paediatr Jpn [Internet].
1995/12/01 ed. 1995;37(6):687–90. Available from: http://www.
ncbi.nlm.nih.gov/pubmed/8775551.
98. Mast EE, Weinbaum CM, Fiore AE, Alter MJ, Bell BP, Finelli L,
et al. A comprehensive immunization strategy to eliminate transmission
of hepatitis B virus infection in the United States: recommendations
of the Advisory Committee on Immunization Practices
(ACIP) Part II: immunization of adults. MMWR Recomm Rep
[Internet]. 2006/12/13 ed. 2006;55(RR-16):1–4. Available from:
http://www.ncbi.nlm.nih.gov/pubmed/17159833.
99. Leuridan E, Van Damme P. Hepatitis B and the need for a booster
dose. Clin Infect Dis [Internet]. 2011/06/10 ed. 2011;53(1):68–75.
Available from: http://www.ncbi.nlm.nih.gov/pubmed/ 21653306.

100. Pozzilli P, Gale EA, Visalli N, Baroni M, Crovari P, Frighi V, et al.


The immune response to influenza vaccination in diabetic patients.
Diabetologia [Internet]. 1986/12/01 ed. 1986;29(12):850–4.
Available from: http://www.ncbi.nlm.nih.gov/pubmed/3569690.
101. Diepersloot RJ, Bouter KP, Beyer WE, Hoekstra JB, Masurel
N. Humoral immune response and delayed type hypersensitivity
to influenza vaccine in patients with diabetes mellitus. Diabetologia
[Internet]. 1987/06/01 ed. 1987;30(6):397–401. Available from:
http://www.ncbi.nlm.nih.gov/pubmed/3678660.
102. Sheridan PA, Paich HA, Handy J, Karlsson EA, Schultz-Cherry S,
Hudgens M, et al. The antibody response to influenza vaccination
is not impaired in type 2 diabetics. Vaccine. Netherlands.
2015;33(29):3306–13.
103. Frasca D, Diaz A, Romero M. Et. Young and elderly patients with
type 2 diabetes have optimal B cell responses to the seasonal influenza
vaccine. Vaccine. 2013;31(35):3603–10.
104. Fung E, Kurella Tamura M. Epidemiology and public health concerns
of CKD in older adults. Adv Chronic Kidney Dis [Internet].
Elsevier Ltd; 2016;23(1):8–11. Available from: http://dx.doi.
org/10.1053/j.ackd.2015.10.001.
105. Patients E. Chapter 5: Mortality. Am J Kidney Dis [Internet].
2015;66(1):S145–52. Available from: http://linkinghub.elsevier.
com/retrieve/pii/S0272638615007222.
106. Collins AJ, Foley RN, Chavers B, Gilbertson D, Herzog C,
Johansen K, et al. ‘United States renal data system 2011 annual
data report: atlas of chronic kidney disease & end-stage renal disease
in the United States. Am J Kidney Dis [Internet]. 2011/12/30
ed. 2012;59(1 Suppl 1):A7, e1–420. Available from: http://www.
ncbi.nlm.nih.gov/pubmed/22177944.
107. James MT, Laupland KB, Tonelli M, Manns BJ, Culleton BF,
Hemmelgarn BR, et al. Risk of bloodstream infection in patients
with chronic kidney disease not treated with dialysis. Arch Intern
Med [Internet]. 2008/11/26 ed. 2008;168(21):2333–9. Available
from: http://www.ncbi.nlm.nih.gov/pubmed/19029498.
108. Martin P, Friedman LS. Chronic viral hepatitis and the management
of chronic renal failure. Kidney Int [Internet]. 1995/05/01
ed. 1995;47(5):1231–41. Available from: http://www.ncbi.nlm.
nih.gov/pubmed/7637252.
109. Pesanti EL. Immunologic defects and vaccination in patients with
chronic renal failure. Infect Dis Clin North Am [Internet].
2001/09/26 ed. 2001;15(3):813–32. Available from: http://www.
ncbi.nlm.nih.gov/pubmed/11570143.
110. McGrath LJ, Kshirsagar A V, Cole SR, Wang L, Weber DJ,
Sturmer T, et al. Influenza vaccine effectiveness in patients on
hemodialysis: an analysis of a natural experiment. Arch Intern
Med [Internet]. 2012/04/12 ed. 2012;172(7):548–54. Available
from: http://www.ncbi.nlm.nih.gov/pubmed/22493462.
111. Naqvi SB, Collins AJ. Infectious complications in chronic kidney
disease. Adv Chronic Kidney Dis [Internet]. 2006/07/04 ed.
2006;13(3):199–204. Available from: http://www.ncbi.nlm.nih.
gov/pubmed/16815225.
112. Gilbertson DT, Unruh M, McBean AM, Kausz AT, Snyder JJ,
Collins AJ. Influenza vaccine delivery and effectiveness in end-stage
renal disease. Kidney Int [Internet]. 2003/03/13 ed.
2003;63(2):738–43. Available from: http://www.ncbi.nlm.nih.
gov/pubmed/12631142.
113. Carrero JJ, Stenvinkel P. Inflammation in end-stage renal disease
– what have we learned in 10 years? Semin Dial [Internet].
2010/11/03 ed. 2010;23(5):498–509. Available from: http://www.
ncbi.nlm.nih.gov/pubmed/21039875.
114. Girndt M, Sester U, Sester M, Kaul H, Kohler H. Impaired cellular
immune function in patients with end-stage renal failure. Nephrol
Dial Transpl [Internet]. 1999/11/26 ed. 1999;14(12):2807–10.
Available from: http://www.ncbi.nlm.nih.gov/pubmed/10570074.
115. Descamps-Latscha B, Herbelin A, Nguyen AT, Zingraff J, Jungers
P, Chatenoud L. Immune system dysregulation in uremia. Semin Nephrol [Internet].
1994/05/01 ed. 1994;14(3):253–60. Available
from: http://www.ncbi.nlm.nih.gov/pubmed/8036360.
116. Carrero JJ, Yilmaz MI, Lindholm B, Stenvinkel P. Cytokine dysregulation
in chronic kidney disease: how can we treat it? Blood
Purif [Internet]. 2008/04/19 ed. 2008;26(3):291–9. Available
from: http://www.ncbi.nlm.nih.gov/pubmed/18421214.
117. Girndt M, Sester M, Sester U, Kaul H, Kohler H. Molecular
aspects of T- and B-cell function in uremia. Kidney Int Suppl
[Internet]. 2001/02/13 ed. 2001;78:S206–11. Available from:
http://www.ncbi.nlm.nih.gov/pubmed/11169012.
118. Vaziri ND, Pahl M V, Crum A, Norris K. Effect of uremia on structure
and function of immune system. J Ren Nutr [Internet].
2011/12/28 ed. 2012;22(1):149–56. Available from: http://www.
ncbi.nlm.nih.gov/pubmed/22200433.
119. Matsumoto Y, Shinzato T, Amano I, Takai I, Kimura Y, Morita H,
et al. Relationship between susceptibility to apoptosis and Fas
expression in peripheral blood T cells from uremic patients: a possible
mechanism for lymphopenia in chronic renal failure.
Biochem Biophys Res Commun [Internet]. 1995/10/04 ed.
1995;215(1):98–105. Available from: http://www.ncbi.nlm.nih.
gov/pubmed/7575631.
120. Moser B, Roth G, Brunner M, Lilaj T, Deicher R, Wolner E, et al.
Aberrant T cell activation and heightened apoptotic turnover in
end-stage renal failure patients: a comparative evaluation between
non-dialysis, haemodialysis, and peritoneal dialysis. Biochem
Biophys Res Commun [Internet]. 2003/08/14 ed.
2003;308(3):581–5. Available from: http://www.ncbi.nlm.nih.
gov/pubmed/12914790.
121. Yoon JW, Gollapudi S, Pahl M V, Vaziri ND. Naive and central
memory T-cell lymphopenia in end-stage renal disease. Kidney
Int [Internet]. 2006/06/02 ed. 2006;70(2):371–6. Available from:
http://www.ncbi.nlm.nih.gov/pubmed/16738532.
122. Smogorzewski M, Massry SG. Defects in B-cell function and
metabolism in uremia: role of parathyroid hormone. Kidney Int
Suppl [Internet]. 2001/02/13 ed. 2001;78:S186–9. Available from:
http://www.ncbi.nlm.nih.gov/pubmed/11169008.
123. Pahl M V, Gollapudi S, Sepassi L, Gollapudi P, Elahimehr R, Vaziri
ND. Effect of end-stage renal disease on B-lymphocyte subpopulations,
IL-7, BAFF and BAFF receptor expression. Nephrol Dial
Transpl [Internet]. 2009/08/18 ed. 2010;25(1):205–12. Available
from: http://www.ncbi.nlm.nih.gov/pubmed/19684120.
124. Beaman M, Michael J, MacLennan IC, Adu D. T-cell-independent
and T-cell-dependent antibody responses in patients with chronic
renal failure. Nephrol Dial Transpl [Internet]. 1989/01/01 ed.
1989;4(3):216–21. Available from: http://www.ncbi.nlm.nih.gov/
pubmed/2498780.
125. Lim WH, Kireta S, Leedham E, Russ GR, Coates PT. Uremia
impairs monocyte and monocyte-derived dendritic cell function in
hemodialysis patients. Kidney Int [Internet]. 2007/08/31 ed.
2007;72(9):1138–48. Available from: http://www.ncbi.nlm.nih.
gov/pubmed/17728708.
126. Lim WH, Kireta S, Russ GR, Coates PT. Uremia impairs blood
dendritic cell function in hemodialysis patients. Kidney Int
[Internet]. 2007/03/23 ed. 2007;71(11):1122–31. Available from:
http://www.ncbi.nlm.nih.gov/pubmed/17377508.
127. Alexiewicz JM, Smogorzewski M, Fadda GZ, Massry SG. Impaired
phagocytosis in dialysis patients: studies on mechanisms. Am
J Nephrol [Internet]. 1991/01/01 ed. 1991;11(2):102–11. Available
from: http://www.ncbi.nlm.nih.gov/pubmed/1951470.
128. Massry S, Smogorzewski M. Dysfunction of polymorphonuclear
leukocytes in uremia: role of parathyroid hormone. Kidney Int
Suppl [Internet]. 2001/02/13 ed. 2001;78:S195–6. Available from:
http://www.ncbi.nlm.nih.gov/pubmed/11169010.
129. Bochicchio GV, Joshi M, Knorr KM, Scalea TM. Impact of nosocomial
infections in trauma: does age make a difference?

130. Baëhl S, Garneau H, Le Page A, Lorrain D, Viens I, Svotelis A,


et al. Altered neutrophil functions in elderly patients during a
6-month follow-up period after a hip fracture. Exp Gerontol
[Internet]. 2015;65:58–68. Available from: http://www.ncbi.nlm.
nih.gov/pubmed/25797136.
131. Nacionales DC, Szpila B, Ungaro R, Lopez MC, Zhang J, Gentile
LF, et al. A detailed characterization of the dysfunctional immunity
and abnormal myelopoiesis induced by severe shock and trauma in
the aged. J Immunol [Internet]. 2015;195(5):2396–407. Available
from: http://www.jimmunol.org/content/195/5/2396.full.
132. Ottinger ME, Monaghan SF, Gravenstein S, Cioffi WG, Ayala A,
Heffernan DS. The geriatric cytokine response to trauma: time to
consider a new threshold. Surg Infect. 2014;15(6):800–5.
133. Metlay JP, Schulz R, Li YH, Singer DE, Marrie TJ, Coley CM,
et al. Influence of age on symptoms at presentation in patients with
community-acquired pneumonia. Arch Intern Med [Internet].
1997/07/14 ed. 1997;157(13):1453–9. Available from: http://
www.ncbi.nlm.nih.gov/pubmed/9224224.
134. Meyer KC. Lung infections and aging. Ageing Res Rev [Internet].
2004/05/28 ed. 2004;3(1):55–67. Available from: http://www.
ncbi.nlm.nih.gov/pubmed/15163102.
135. Gomolin IH, Aung MM, Wolf-Klein G, Auerbach C. Older is
colder: temperature range and variation in older people. J Am
Geriatr Soc [Internet]. 2006/01/10 ed. 2005;53(12):2170–2.
Available from: http://www.ncbi.nlm.nih.gov/pubmed/16398904.
136. High KP. Infection as a cause of age-related morbidity and mortality.
Ageing Res Rev [Internet]. 2004/05/28 ed. 2004;3(1):1–14.
Available from: http://www.ncbi.nlm.nih.gov/pubmed/15163100.
137. Roghmann MC, Warner J, Mackowiak PA. The relationship
between age and fever magnitude. Am J Med Sci [Internet].
2001/08/29 ed. 2001;322(2):68–70. Available from: http://www.
ncbi.nlm.nih.gov/pubmed/11523629.
138. Norman DC. Fever in the elderly. Clin Infect Dis [Internet].
2000/07/29 ed. 2000;31(1):148–51. Available from: http://www.
ncbi.nlm.nih.gov/pubmed/10913413.
139. Chassagne P, Perol MB, Doucet J, Trivalle C, Menard JF, Manchon
ND, et al. Is presentation of bacteremia in the elderly the same as
in younger patients? Am J Med [Internet]. 1996/01/01 ed.
1996;100(1):65–70. Available from: http://www.ncbi.nlm.nih.
gov/pubmed/8579089.
140. Gavazzi G, Krause KH. Ageing and infection. Lancet Infect Dis
[Internet]. 2002/11/01 ed. 2002;2(11):659–66. Available from:
http://www.ncbi.nlm.nih.gov/pubmed/12409046.
141. High KP, Bradley SF, Gravenstein S, Mehr DR, Quagliarello VJ,
Richards C, et al. Clinical practice guideline for the evaluation of
fever and infection in older adult residents of long-term care
facilities: 2008 update by the Infectious Diseases Society of
America. Clin Infect Dis [Internet]. 2008/12/17 ed.
2009;48(2):149–71. Available from: http://www.ncbi.nlm.nih.
gov/pubmed/19072244.
142. Yoshikawa TT. Epidemiology and unique aspects of aging and
infectious diseases. Clin Infect Dis [Internet]. 2000/07/06 ed.
2000;30(6):931–3. Available from: http://www.ncbi.nlm.nih.gov/
pubmed/10880303.
143. Marrie TJ. Community-acquired pneumonia in the elderly. Clin
Infect Dis [Internet]. 2000/10/26 ed. 2000;31(4):1066–78.
Available from: http://www.ncbi.nlm.nih.gov/pubmed/11049791.
144. Molinos L, Clemente MG, Miranda B, Alvarez C, del Busto B,
Cocina BR, et al. Community-acquired pneumonia in patients
with and without chronic obstructive pulmonary disease. J Infect
[Internet]. 2009/03/31 ed. 2009;58(6):417–24. Available from:
http://www.ncbi.nlm.nih.gov/pubmed/19329187.
145. Ronald A. The etiology of urinary tract infection: traditional and
emerging pathogens. Am J Med [Internet]. 2002/07/13 ed.
2002;113 Suppl :14S – 19S. Available from: http://www.ncbi.nlm.
nih.gov/pubmed/12113867.
146. Lye WC, Chan RK, Lee EJ, Kumarasinghe G. Urinary tract infections
in patients with diabetes mellitus. J Infect [Internet].
1992/03/01 ed. 1992;24(2):169–74. Available from: http://www.
ncbi.nlm.nih.gov/pubmed/1569307.
147. Smith PW, Bennett G, Bradley S, Drinka P, Lautenbach E, Marx J,
et al. SHEA/APIC Guideline: infection prevention and control in
the long-term care facility. Am J Infect Control [Internet].
2008/09/13 ed. 2008;36(7):504–35. Available from: http://www.
ncbi.nlm.nih.gov/pubmed/18786461.
148. Daneman N, Gruneir A, Newman A, Fischer HD, Bronskill SE,
Rochon PA, et al. Antibiotic use in long-term care facilities.
J Antimicrob Chemother [Internet]. 2011/09/29 ed.
2011;66(12):2856–63. Available from: http://www.ncbi.nlm.nih.
gov/pubmed/21954456.
149. Levy SB. Antibiotic resistance: consequences of inaction. Clin
Infect Dis [Internet]. 2001/08/29 ed. 2001;33 Suppl 3:S124–9.
Available from: http://www.ncbi.nlm.nih.gov/pubmed/11524708.
150. Guillemot D, Carbon C, Balkau B, Geslin P, Lecoeur H, Vauzelle-Kervroedan
F, et al. Low dosage and long treatment duration of
beta-lactam: risk factors for carriage of penicillin-resistant
Streptococcus pneumoniae. JAMA [Internet]. 1998/02/12 ed.
1998;279(5):365–70. Available from: http://www.ncbi.nlm.nih.
gov/pubmed/9459469.
151. Parish A, Holliday K. Long-term care acquired urinary tract infections’
antibiotic resistance patterns and empiric therapy: a pilot
study. Geriatr Nurs [Internet]. 2012/07/04 ed. 2012; Available
from: http://www.ncbi.nlm.nih.gov/pubmed/22749357.
152. van Buul LW, van der Steen JT, Veenhuizen RB, Achterberg WP,
Schellevis FG, Essink RT, et al. Antibiotic use and resistance in
long term care facilities. J Am Med Dir Assoc [Internet].
2012/05/12 ed. 2012;13(6):568 e1–568 e13. Available from:
http://www.ncbi.nlm.nih.gov/pubmed/22575772.
153. Richards CL. Urinary tract infections in the frail elderly: issues for
diagnosis, treatment and prevention. Int Urol Nephrol [Internet].
2005/03/24 ed. 2004;36(3):457–63. Available from: http://www.
ncbi.nlm.nih.gov/pubmed/15783124.
154. Herrmann V, Palma P, Geo MS, Lima RS. Urinary tract infections:
pathogenesis and related conditions. Int Urogynecol J Pelvic
Floor Dysfunct [Internet]. 2002/07/26 ed. 2002;13(3):210–3.
Available from: http://www.ncbi.nlm.nih.gov/pubmed/12140720.
155. Pfisterer MH, Griffiths DJ, Schaefer W, Resnick NM. The effect of
age on lower urinary tract function: a study in women. J Am
Geriatr Soc [Internet]. 2006/03/23 ed. 2006;54(3):405–12.
Available from: http://www.ncbi.nlm.nih.gov/pubmed/16551306.
156. Htwe TH, Mushtaq A, Robinson SB, Rosher RB, Khardori
N. Infection in the elderly. Infect Dis Clin North Am.
2007;21(3):711–43.
157. Yoshikawa TT, Nicolle LE, Norman DC. Management of complicated
urinary tract infection in older patients. J Am Geriatr Soc
[Internet]. 1996/10/01 ed. 1996;44(10):1235–41. Available from:
http://www.ncbi.nlm.nih.gov/pubmed/8856005.
158. Brauner A, Flodin U, Hylander B, Ostenson CG. Bacteriuria, bacterial
virulence and host factors in diabetic patients. Diabet Med
[Internet]. 1993/07/01 ed. 1993;10(6):550–4. Available from:
http://www.ncbi.nlm.nih.gov/pubmed/8365092.
159. Hansen DS, Gottschau A, Kolmos HJ. Epidemiology of Klebsiella
bacteraemia: a case control study using Escherichia coli bacteraemia
as control. J Hosp Infect [Internet]. 1998/04/02 ed.
1998;38(2):119–32. Available from: http://www.ncbi.nlm.nih.
gov/pubmed/9522290.
160. Nicolle LE. Urinary tract infection in long-term-care facility residents.
Clin Infect Dis [Internet]. 2000/10/06 ed. 2000;31(3):757–61.
Available from: http://www.ncbi.nlm.nih.gov/pubmed/11017826.
161. Nicolle LE, Bradley S, Colgan R, Rice JC, Schaeffer A, Hooton
TM, et al. Infectious Diseases Society of America guidelines for
the diagnosis and treatment of asymptomatic bacteriuria in adults. Clin Infect Dis
[Internet]. 2005/02/17 ed. 2005;40(5):643–54.
Available from: http://www.ncbi.nlm.nih.gov/pubmed/15714408.
162. Nicolle LE. Asymptomatic bacteriuria: review and discussion of
the IDSA guidelines. Int J Antimicrob Agents [Internet].
2006/07/11 ed. 2006;28 Suppl 1:S42–8. Available from: http://
www.ncbi.nlm.nih.gov/pubmed/16829049.
163. Rowe TA, Juthani-Mehta M. Diagnosis and management of urinary
tract infection in older adults. Infect Dis Clin North Am.
2014;28(1):76–89.
164. Vogel T, Verreault R, Gourdeau M, Morin M, Grenier-Gosselin L,
Rochette L. Optimal duration of antibiotic therapy for uncomplicated
urinary tract infection in older women: a double-blind randomized
controlled trial. CMAJ [Internet]. 2004/02/19 ed.
2004;170(4):469–73. Available from: http://www.ncbi.nlm.nih.
gov/pubmed/14970093.
165. Lutters M, Vogt-Ferrier NB. Antibiotic duration for treating
uncomplicated, symptomatic lower urinary tract infections in
elderly women. Cochrane Database Syst Rev [Internet].
2008/07/23 ed. 2008;(3):CD001535. Available from: http://www.
ncbi.nlm.nih.gov/pubmed/18646074.
166. Nicolle LE. Urinary tract infections in the elderly. Clin Geriatr
Med [Internet]. 2009/09/22 ed. 2009;25(3):423–36. Available
from: http://www.ncbi.nlm.nih.gov/pubmed/19765490.
167. Hooton TM, Bradley SF, Cardenas DD, Colgan R, Geerlings SE,
Rice JC, et al. Diagnosis, prevention, and treatment of catheter-associated
urinary tract infection in adults: 2009 International
Clinical Practice Guidelines from the Infectious Diseases Society
of America. Clin Infect Dis [Internet]. 2010/02/23 ed.
2010;50(5):625–63. Available from: http://www.ncbi.nlm.nih.
gov/pubmed/20175247.
168. Jackson ML, Neuzil KM, Thompson WW, Shay DK, Yu O,
Hanson CA, et al. The burden of community-acquired pneumonia
in seniors: results of a population-based study. Clin Infect Dis
[Internet]. 2004;39(11):1642–50. Available from: http://www.
ncbi.nlm.nih.gov/pubmed/15578365.
169. Niederman MS. Guidelines for the management of respiratory
infection: why do we need them, how should they be developed,
and can they be useful? Curr Opin Pulm Med [Internet].
1996/05/01 ed. 1996;2(3):161–5. Available from: http://www.
ncbi.nlm.nih.gov/pubmed/9363134.
170. Tablan OC, Anderson LJ, Besser R, Bridges C, Hajjeh R, Cdc,
et al. Guidelines for preventing health-care – associated pneumonia,
2003: recommendations of CDC and the Healthcare Infection
Control Practices Advisory Committee. MMWR Recomm Rep
[Internet]. 2004/03/30 ed. 2004;53(RR-3):1–36. Available from:
http://www.ncbi.nlm.nih.gov/pubmed/15048056.
171. Craven DE, Kunches LM, Kilinsky V, Lichtenberg DA, Make BJ,
McCabe WR. Risk factors for pneumonia and fatality in patients
receiving continuous mechanical ventilation. Am Rev Respir Dis
[Internet]. 1986/05/01 ed. 1986;133(5):792–6. Available from:
http://www.ncbi.nlm.nih.gov/pubmed/3706887.

172. El-Solh AA, Sikka P, Ramadan F, Davies J. Etiology of severe


pneumonia in the very elderly. Am J Respir Crit Care Med. United
States; 2001;163(3 Pt 1):645–651.
173. Mandell LA, Bartlett JG, Dowell SF, File TM, Musher DM,
Whitney C, et al. Update of practice guidelines for the management
of community-acquired pneumonia in immunocompetent
adults. Clin Infect Dis [Internet]. 2003;37(11):1405–33. Available
from: http://www.ncbi.nlm.nih.gov/pubmed/14614663
174. American Thoracic S, Infectious Diseases Society of
A. Guidelines for the management of adults with hospitalacquired,
ventilator-associated,
and healthcare-associated pneumonia.
Am J Respir Crit Care Med [Internet]. 2005/02/09 ed.
2005;171(4):388–416. Available from: http://www.ncbi.nlm.nih.
gov/pubmed/15699079.
175. Thiem U, Heppner HJ, Pientka L. Elderly patients with
community-acquired
pneumonia: optimal treatment strategies.
Drugs Aging [Internet]. 2011/07/05 ed. 2011;28(7):519–37.
Available from: http://www.ncbi.nlm.nih.gov/pubmed/ 21721597.
176. Gross AE, Van Schooneveld TC, Olsen KM, Rupp ME, Bui TH,
Forsung E, et al. Epidemiology and predictors of multidrug-resistant
community-acquired and health care-associated pneumonia.
Antimicrob Agents Chemother [Internet]. 2014;58(9):5262–8.
Available from: http://www.ncbi.nlm.nih.gov/pubmed/24957843
177. Spielmann G, McFarlin BK, O’Connor DP, Smith PJW, Pircher H,
Simpson RJ. Aerobic fitness is associated with lower proportions
of senescent blood T-cells in man. Brain Behav Immun [Internet].
Elsevier Inc.; 2011;25(8):1521–9. Available from: http://dx.doi.
org/10.1016/j.bbi.2011.07.226.
178. Kohut ML, Arntson BA, Lee W, Rozeboom K, Yoon K-J, Cunnick
JE, et al. Moderate exercise improves antibody response to influenza
immunization in older adults. Vaccine [Internet]. 2004;22(17–
18):2298–306. Available from: http://www.ncbi.nlm.nih.gov/
pubmed/15149789
179. Woods JA, Keylock KT, Lowder T, Vieira VJ, Zelkovich W,
Dumich S, et al. Cardiovascular exercise training extends influenza
vaccine seroprotection in sedentary older adults: the immune
function intervention trial. J Am Geriatr Soc [Internet].
2009;57(12):2183–91. Available from: http://www.ncbi.nlm.nih.
gov/pubmed/20121985
180. Szarcvel Szic K, Declerck K, Vidaković M, Vanden Berghe
W. From inflammaging to healthy aging by dietary lifestyle
choices: is epigenetics the key to personalized nutrition? Clin
Epigenetics [Internet]. 2015;7(1):33. Available from: http://www.
pubmedcentral.nih.gov/articlerender.fcgi?artid=4389409&tool=p
mcentrez&rendertype=abstract
181. Ostan R, Lanzarini C, Pini E, Scurti M, Vianello D, Bertarelli C,
et al. Inflammaging and cancer: a challenge for the mediterranean
diet. Nutrient. 2015;7(4):2589–621.
182. Shayganni E, Bahmani M, Asgary S, Rafieian-Kopaei
M. Inflammaging and cardiovascular disease: management by
medicinal plants. Phytomedicine Elsevier GmbH; 2015;23:1–8.

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