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J Neurosurg Spine 10:201–206,

10:000–000, 2009

Thoracolumbar spine trauma classification: the


Thoracolumbar Injury Classification and
Severity Score system and case examples

Clinical article
Alpesh A. Patel, M.D.,1 Andrew Dailey, M.D., 2 Darrel S. Brodke, M.D.,1
Michael Daubs, M.D.,1 James Harrop, M.D., 3 Peter G. Whang, M.D., 5
Alexander R. Vaccaro, M.D., Ph.D., 4 and the Spine Trauma Study Group
Departments of 1Orthopaedic Surgery and 2Neurosurgery, University of Utah School of Medicine, Salt Lake
City, Utah; Departments of 3Neurosurgery and 4Orthopaedic Surgery, Thomas Jefferson University,
Philadelphia, Pennsylvania; and 5Department of Orthopaedic Surgery and Rehabilitation, Yale University,
New Haven, Connecticut

Object. The aim of this study was to review the Thoracolumbar Injury Classification and Severity Score (TLICS)
and to demonstrate its application through a series of spine trauma cases.
Methods. The Spine Trauma Study Group collaborated to create and report the TLICS system. The TLICS sys-
tem is reviewed and applied to 3 cases of thoracolumbar spine trauma.
Results. The TLICS system identifies 3 major injury characteristics to describe thoracolumbar spine injuries:
injury morphology, posterior ligamentous complex integrity, and neurological status. In addition, minor injury char-
acteristics such as injury level, confounding variables (such as ankylosing spondylitis), multiple injuries, and chest
wall injuries are also identified. Each major characteristic is assigned a numerical score, weighted by severity of
injury, which is then summated to yield the injury severity score. The TLICS system has demonstrated initial success
and its use is increasing. Limitations of the TLICS system exist and, in some instances, have yet to be addressed.
Despite these limitations, the severity score may provide a basis to judge spinal stability and the need for surgical
intervention.
Conclusions. By addressing both the posterior ligamentous integrity and the patient’s neurological status, the
TLICS system attempts to overcome the limitations of prior thoracolumbar classification systems. The TLICS system
has demonstrated both validity and reliability and has also been shown to be readily learned and incorporated into
clinical practice. (DOI: 10.3171/2008.12.SPINE08388)

Key Words      •      injury classification      •      injury severity score      •      spinal cord injury      •   
Thoracolumbar Injury Classification and Severity Score      •      thoracolumbar spine trauma

I
njuries to the thoracic and lumbar spine account for A number of classification systems have been devel-
> 50% of all spinal fractures and a large portion of oped in an attempt to better define thoracolumbar trauma
acute spinal cord injuries.7 Given this frequency and and aid treatment decision-making. These systems are
the significant impact of these injuries, significant ad- typically based on either anatomical structures (Denis
vancements have been made in the surgical treatment of Three-Column System) or on proposed mechanisms
thoracolumbar trauma. Despite the invention and con- of injury (Ferguson and Allen, and the AO system).2,3,6
tinued evolution of spinal instrumentation and surgical Overall, however, there is a paucity of strong data sup-
techniques, medical decision-making in spine trauma re- porting the use of any of these systems. Additionally,
mains controversial. Fracture treatment can vary widely, there is currently no clear consensus regarding the opti-
from bracing to invasive 360° fusions, based on geo- mal system for characterizing thoracolumbar fractures.
graphical, institutional, or individual preferences with An ideal system must be simple and reproducible based
little scientific basis. on commonly identified clinical and radiographic param-
eters. Current systems are either excessively convoluted,
with an impractical number of variables, or are too sim-
Abbreviations used in this paper: AO = Arbeitsgemeinschaft für ple, lacking sufficient detail to provide clinically relevant
Osteosynthesefragen; ASIA = American Spinal Injury Association; information. These limitations have yielded classification
PLC = posterior ligamentous complex; TLICS = Thoracolumbar systems that are difficult to implement, have shown in-
Injury Classification and Severity Score.

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A. A. Patel et al.

sufficient validity and reproducibility, and have not been Table 1: Thoracolumbar injury classification and severity score
widely popular.1,6,8,16 scale
The TLICS has been described and validated to ad-
dress the shortcomings of the prior classification systems. Category Points
The purpose of this paper is to review the TLICS system injury morphology
and to demonstrate its clinical application using 3 cases
   compression 1
of thoracolumbar spine trauma.
     burst +1

Methods    translational/rotational 3
   distraction 4
The TLICS, introduced by the Spine Trauma Study
Group in 2005, was designed to provide a clear, reliable neurological status
classification system that accounts for many of the short-    intact 0
comings of prior systems.14 The system has demonstrated    nerve root 2
good to excellent inter- and intraobserver reliability and    cord, conus medullaris
has also been shown to be easily taught, learned, and in-
corporated into clinical practice.11,12,14,15 The TLICS sys-      incomplete 3
tem assigns numerical values to each injury based on the      complete 2
categories of morphology of injury, integrity of the PLC,      cauda equina 3
and neurological involvement (Table 1).
PLC
Injury Morphology    intact 0
Compression injuries are defined by a visible loss of    injury suspected/indeterminate 2
height of the vertebral body or disruption through the ver-    injured 3
tebral endplate. This category includes traditional com-
pression (anterior vertebral body) and burst (involvement
of the posterior vertebral wall) fractures as well as sagit-
tal or coronal plane fractures of the vertebrae. distraction has been well described.9,10 Furthermore, once
The rotation/translation injury is defined by hori- disrupted, the ligamentous structures have poor healing
zontal displacement of one vertebral body with respect ability and generally require surgical stabilization.
to another (Fig. 1A). It is typified by unilateral and bilat- The integrity of the PLC is categorized as intact, in-
eral dislocations, facet fracture dislocations, and bilateral determinate, or disrupted. This assessment can be made
pedicle or pars fractures with vertebral subluxation (trau- from plain radiographs, CT scans, and MR images.5 Dis-
matic spondylolisthesis). ruption is typically indicated by splaying of the spinous
The distraction injury pattern is readily identified by processes (widening of the interspinous space), widening
anatomical dissociation in the vertical axis. A represen- of the facet joints, empty facet joints, facet perch or sub-
tative example would be a hyperextension injury caus- luxation, or dislocation of the spine. Other measures of
ing disruption of the anterior longitudinal ligament with posterior ligamentous disruption include vertebral body
subsequent widening of the anterior disc space. Posterior translation or rotation.
element fractures (facet, lamina, or spinous process) may When the evidence of disruption is subtle, the integ-
also be present. Thoracolumbar kyphotic deformities of rity of the ligaments is labeled “indeterminate.” In some
the spine, through a tensile failure of the posterior liga- cases, clinical examination may be helpful in determin-
mentous restraints, represent another clinical example of ing the status of the PLC as an obvious gap between the
the distraction morphology. spinous processes indicates PLC disruption. Magnetic
If more than 1 injury morphology is present, then the resonance images may show areas of high signal intensity
single injury morphology with the largest score is used. on STIR or T2-weighted imaging, suggesting PLC injury.
For example, a T11–12 distraction injury with a T-12 burst However, MR imaging findings of the PLC have yet to
fracture would be classified as a distraction injury and be reproducibly proven to correlate with anatomical dis-
assigned 4 points (Table 1); scores for the burst fracture ruption.4 Therefore, unless CT scans or plain radiographs
morphology are not used. If multiple levels of involve- demonstrate clear disruption, MR imaging suggesting
ment are present, each injury can be assessed indepen- PLC injury may be best classified as indeterminate.
dently. For example, an individual with a T-5 burst frac-
ture (2 points) and a T-9 compression fracture (1 point) is Neurological Status
assigned a different TLICS score for each injury. The neurological status of the patient is often the
most influential component of medical decision-making.
Integrity of the PLC
Additionally, it can be inferred that neurological injury
The PLC includes the supraspinous ligament, inter­ is a critical indicator of the degree of spinal column in-
spinous ligament, ligamentum flavum, and facet joint cap- jury. In addition, incomplete neurological injury in the
sules. The importance of this complex in protecting the setting of neural compression is generally accepted as
spine against excessive flexion, rotation, translation, and an indication for surgical decompression. The neurologi-

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Thoracolumbar injury classification system and severity score

Fig. 1.  Case 1. Images obtained in an 18-year-old female who sustained a fall of 10 ft off of a horse and presented with an
incomplete spinal cord injury (ASIA Grade B).  A: Lateral radiograph demonstrating a T10–11 dislocation.  B: Sagittal CT scan
demonstrating dislocation with associated fractures of the vertebral body and posterior elements.  C: Sagittal T2-weighted MR
image reveals compression on the spinal cord from the spinal deformity and disruption of the posterior ligamentous structures.

cal status is described in increasing order of urgency as: sation in the perineal and perirectal region and the lower
neurologically intact, nerve root injury, complete (motor extremities.
and sensory) spinal cord injury, and incomplete (motor or TLICS Classification: T10–11 translational injury
sensory) spinal cord or cauda equina injury. The incom- with a disrupted PLC and an incomplete spinal cord in-
plete spinal cord injuries are considered ASIA Grades B, jury.
C, or D, while the complete injuries are considered ASIA TLICS Score: Injury Morphology (Translation) = 3
Grade A. points; PLC (Disrupted) = 3 points; Neurological Status
A numerical value is assigned for each injury subcat- (Incomplete) = 3 points; Total TLICS score = 9 points
egory dependent on the severity of injury. These individu- (operative treatment).
al scores are then summated to produce an injury severity
score, which is, in turn, used to guide treatment (Table Case 2
1). A score of ≥ 5 (Cases 1 and 3, below) suggests opera- This patient (Fig. 2) was a 42-year-old male involved
tive treatment of the patient due to significant instability, in a high-speed motor vehicle collision who presented
whereas a score of ≤ 3 (Case 2) suggests nonoperative with back pain but no neurological deficits.
treatment; a patient with a score of 4 may be treated either TLICS Classification: T-12 burst fracture with an in-
operatively or conservatively. In the setting of multiple tact PLC and normal neurological examination results.
fractures, the injury with the greatest TLICS score is used TLICS Score: Injury Morphology (Burst) = 2 points;
to guide treatment. PLC (Intact) = 0 points; Neurological Status (Intact) = 0
points; Total TLICS score = 2 points (nonoperative treat-
Summary of Cases ment).

Three cases of thoracolumbar trauma are presented Case 3


to demonstrate use of the TLICS system and its ability to This patient (Fig. 3) was a 23-year-old male who pre-
guide surgical decision–making. sented after a 25-ft fall with subsequent back pain and
lower-extremity weakness and numbness consistent with
Case 1
an incomplete cauda equina injury.
This patient (Fig. 1) was an 18-year-old female who TLICS Classification: L-2 burst fracture with inde-
sustained a fall from 10 ft after being thrown from a terminate PLC injury and an incomplete cauda equina
horse. She presented with an incomplete spinal cord in- injury.
jury (ASIA Grade B) with severe weakness in the lower TLICS Score: Injury Morphology (Burst) = 2 points;
extremities but maintained light touch and pinprick sen- PLC (Indeterminate/Suspected) = 2 points; Neurological

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A. A. Patel et al.

Fig. 2.  Case 2. Images obtained in a 42-year-old male involved in a high-speed motor vehicle collision who presented with
back pain but no neurological deficits.  A: Sagittal CT scan reveals a T-12 burst fracture with no kyphotic or translational defor-
mity.  B: Axial CT scan demonstrates T-12 fracture retropulsion and 20% canal stenosis.  C: Sagittal T2-weighted MR image
demonstrates intact posterior ligamentous structures with no increased signal intensity.

Status (Incomplete) = 3 points; Total TLICS Score = 7 in medical decision-making by providing both diagnostic
points (operative treatment). and prognostic information with a weighted injury sever-
ity score. Stable injury patterns (TLICS < 4) may be treat-
ed nonoperatively with brace immobilization and active
Discussion patient mobilization. Unstable injury patterns (TLICS >
Treatment of thoracolumbar spinal trauma is based 4) may be treated operatively with the guiding principles
on a systematic evaluation of the clinical and radio- of deformity correction, neurological decompression if
graphic information available on the patient at the time necessary, and spinal stabilization followed by active pa-
of assessment. Classification systems have been devel- tient mobilization.
oped to help physicians categorize this information and The TLICS system has shown good to excellent in-
synthesize a treatment strategy. Prior systems have been tra- and interobserver reliability in a number of countries,
based on either injury to specific anatomical structures including with both orthopedic surgeons and neurosur-
(Denis Three-Column System) or proposed mechanisms geons, and throughout a spectrum of spine treatment
of injury (Ferguson and Allen, and the AO system).2,3,6 providers with varying levels of experience.11,12,14,15 The
An inherent limitation of the latter system is that injuries TLICS system has been tested in the setting of an aca-
are classified by inferring unknown injury patterns rather demic trauma center, verifying that physicians in training
than by a description of known or presenting injury mor- (residents and fellows) can readily be taught and incorpo-
phology. Not surprisingly, significant interobserver vari- rate the TLICS system into patient care.11 Furthermore,
ability has been noted with mechanistic classifications.13 use of the TLICS has yielded > 90% agreement in the
Blauth et al.1 demonstrated only fair (κ = 0.33) interob- management of thoracolumbar trauma across a number
server reliability of the AO system with 3 main categories of providers.14
(A, B, and C); as injury subtypes were included, reliability Although the TLICS system has demonstrated suc-
decreased significantly. Wood and colleagues16 and Oner cess, there are inherent limitations. To date, many of the
et al.8 independently demonstrated fair interobserver reli- investigations into the TLICS system have been performed
ability of the AO system and fair to good reliability of the by individuals involved with its development. Whereas
Denis classification system. the system has demonstrated educational efficacy,11 a
The TLICS system has been designed to address broader application of the system across multiple physi-
these limitations. The TLICS system defines injuries cians and trauma centers may further validate or refute
according to injury morphology, integrity of the PLC, the TLICS system. Additionally, a prospective application
and neurological status of the patient. It is the first tho- of the TLICS system and severity score to the treatment
racolumbar system to use injury morphology combined of spinal injuries is needed to define any improvements in
with the neurological status of the patient and the criti- care and patient outcomes compared with conventional
cal importance of the posterior ligamentous structures in systems. Lastly, there are certain injury patterns that may
medical decision-making. be difficult to classify and score. The following case is an
As such, the TLICS system has been designed to aid example of the limitations of the TLICS system.

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Thoracolumbar injury classification system and severity score

Fig. 3.  Case 3. Images obtained in a 23-year-old male who presented after a 25-ft fall out of a tree with resulting back pain
and an incomplete cauda equina injury.  A: Sagittal CT scan demonstrates an L-2 burst fracture.  B: Axial CT scan showing
the burst pattern at L-2 with 90% canal stenosis.  C: Sagittal T2-weighted MR image demonstrates compression of the cauda
equina and possible signal change in the PLC.

Fig. 4.  Images obtained in a 68-year-old male with ankylosing spondylitis who was involved in a ground-level fall and sub-
sequently presented with back pain and normal neurological examination results.  A: Sagittal CT scan demonstrates a T9–10
distraction injury with anterior, middle, and posterior column involvement (arrows).  B: Sagittal STIR MR image demonstrates an
increased signal at the level of the fracture but intact ligamentous structures.  C: Sagittal T2-weighted MR image demonstrates
no anatomical disruption of the PLC.

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A. A. Patel et al.

A 68-year-old male with ankylosing spondylitis pre-   5.  Lee JY, Vaccaro AR, Schweitzer KM, Lim MR, Baron EM,
sented with back pain and normal neurological examina- Rampersaud R, et al: Assessment of injury to the thoracolum-
tion results after a ground-level fall (Fig. 4). His TLICS bar posterior ligamentous complex in the setting of normal-
classification was a T9–10 distraction injury with an intact appearing plain radiography. Spine J 7:422–427, 2007
  6.  Magerl F, Aebi M, Gertzbein SD, Harms J, Nazarian S: A
PLC and normal neurological examination. His TLICS comprehensive classification of thoracic and lumbar injuries.
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PLC (Intact) = 0 points, Neurological Status (Intact) =   7.  National SCI Statistical Center (US): Spinal Cord Injury
0 points, and Total TLICS score = 4 points (operative or Facts & Figures at a Glance 2008. Birmingham, AL: The
nonoperative treatment). This case example demonstrates National SCI Statistical Center, 2008 (http://www.spinalcord.
a number of limitations. The patient’s bone injury is a uab.edu/show.asp?durki=116979) [Accessed 15 December
distraction injury, but the PLC is anatomically intact. Al- 2008]
though this patient’s fracture was not severe, others with   8.  Oner FC, Ramos LM, Simmermacher RK, Diekerhof CH,
greater fracture displacement or angulation would be Dhert WJ, Verbout AJ: Classification of thoracic and lumbar
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Conclusions Spine 32:E105–E110, 2007
12.  Raja Rampersaud Y, Fisher C, Wilsey J, Arnold P, Anand N,
This paper has demonstrated the application of the Bono CM, et al: Agreement between orthopedic surgeons and
TLICS system, a significant improvement over current neurosurgeons regarding a new algorithm for the treatment of
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cal determinants for medical decision-making and prog- nal Disord Tech 19:477–482, 2006
nosis. Future prospective studies with the TLICS will 13.  Schweitzer KM Jr, Vaccaro AR, Lee JY, Grauer JN: Confu-
help to further define its role in the care of thoracolumbar sion regarding mechanisms of injury in the setting of thora-
spine trauma. columbar spinal trauma: a survey of The Spine Trauma Study
Group (STSG). J Spinal Disord Tech 19:528–530, 2006
14.  Vaccaro AR, Lehman RA Jr, Hulbert RJ, Anderson PA, Har-
Disclosure ris M, Hedlund R, et al: A new classification of thoracolumbar
This study was supported by the Spine Trauma Study Group injuries: the importance of injury morphology, the integrity
and funded by an educational/research grant from Medtronic of the posterior ligamentous complex, and neurologic status.
Sofamor Danek. Spine 30:2325–2333, 2005
15.  Whang PG, Vaccaro AR, Poelstra KA, Patel AA, Anderson
DG, Albert TJ, et al: The influence of fracture mechanism and
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ligament complex injury in thoracolumbar spinal fractures. of Orthopaedic Surgery, University of Utah, Salt Lake City, Utah
Spine 25:2079–2084, 2000 84108. email: alpesh.patel@hsc.utah.edu.

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