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TOPICAL OUTLINE
DEFINITION OF TERMS
Chromosomes Mitochondria
Animal Genetics and Breeding
22| AGRICULTURIST LICENSURE EXAMINATION REVIEW 2011 (Animal Science)
Plastids
1. Store and transmit genetic information from cell to cell (cell division) and from parents to
offsprings (meiosis and fertilization)
2. Copy or replicate itself with great consistency and precision
3. Undergo mutation or errors in copying which would undergo subsequent copying and
replication
Mendelian/Non-Mendelian Inheritance
Example:
A. Sex Linkage
Sex-linked genes are responsible for the following diseases such as:
B. Autosomal Linkage
Chromosomes as a chain of genes linked together such that genes that are more closely
linked tend to be inherited together often than those that are located further in the same
chromosome.
C. Non-nuclear Inheritance
Maternal influence - Maternal effects form part of the total environment which can
affect its characters or traits
Example:
Milk production
GENE ACTIONS
Genes - Active only when they occur in pairs of alleles during the diploid phase
Alleles - Genes that occupy the same locus or position in the paired chromosomes
Structural genes - Directly responsible for the synthesis of certain biochemical products
(hormones and enzymes) during cell metabolism
Regulator genes - control and regulate the functions (ON/OFF) of other genes (operator)
- Overdominance
GENES IN POPULATION
Gene pool - Totality of the genes that could potentially be transmitted by individuals in a
population in the next generation
Gene frequency - Relative abundance or rarity of a gene compared to its own allele
in the same population
Hardy Weinberg Law - In an indefinitely large population undergoing random mating, the
gene or genotypic frequencies will remain constant from
generation to generation provided that there are no selection,
migration, mutation and random genetic drift
Random genetic drift - Change in gene frequency because of small population size and
closed to other population
Non-random mating - Some individuals do not have the same chances of mating with
individuals of the opposite sex due to some certain physical,
physiological or psychological factors
Disassortative - Less phenotypically similar individual tend to mate more often than would
be expected by chance
Phenotype (P) = Genotype (G) + Environment (E) + Interaction between Genotype and
Environment (G x E)
Genotype - Specific combination of genes (genetic make – up) that are associated
with a particular characteristic (phenotype) of the individual
MECHANICS OF INHERITANCE
Reproduction - Made possible the flow of genetic materials from one generation to the
next
GAMETOGENESIS
- Ovary in females
REPRODUCTION
Reproduction - Involves the physical and physiological processes in both sexes leading to
the fertilization of the egg (ova) by the sperm cell and the subsequent
development of the young (progeny)
- If more progenies are produced from each female breeder per unit of time,
the chances of producing superior genotypes would be much greater
“Lower reproduction rate retards the rate of genetic improvement because it would require
longer periods to produce enough progenies as reliable basis for selection”
ANIMAL BREEDING
Animal breeding - art and science of the genetic improvement of farm animals
Improve the quantity of production of farm animals and of their products per unit of time
Improve the efficiency of production of farm animals and their products
Improve the quality of farm animals and their products
Improve the aesthetic value of farm animals and their products
Selection - Individuals are preferred to others for the production of the next
generation
Tandem Method
Independent Culling Method
Selection Index
Individuality – phenotype/performance
Pedigree – “clean” or “dirty” ancestry; EBV or EPD
Progeny Test – standardized testing protocols
Collateral Relatives – accuracy depends on information for all relatives
Specific Combining Ability – “nicking ability” due to pleiotrophy
DNA markers – marker assisted selection (MAS)
SYSTEMS OF BREEDING
Examples:
Uses of Inbreeding
Outbreeding/Crossbreeding
Mating between groups of animals of diverse genotypes such as between varieties and lines of
animals
Crossbreeding Schemes
Natural mating
Artificial insemination (AI) in cattle, buffaloes, pigs, goats and sheep
IVM-IVF-MOET/SOET (in vitro maturation-in vitro fertilization-multiple/super ovulation-
embryo transfer) in cattle, buffaloes and small ruminants
Transgenics (rats, pigs, fish, etc.)
Cloning (sheep, cattle, horses pet animals, humans?)
AI - The process of inducing fertilization in the female reproductive tract without the benefit
of sexual contact between the male and female animals
- Semen is usually collected from the genetically superior male processed to extend
volume of semen and in vitro shelf life of sperm cells
IVM-IVF-S/MOET
Ovaries (from
slaughter
houses)
Sheep 1 Transfer
(mammary cells) nucleus
Sheep 3
(Surrogate Female; uterine implantation)
Sheep 2 Remove
(Eggs/Ova) nucleus