References

Biessels, GJ, Staekenborg, S, Brunner, E, Brayne, C and Scheltens P, Risk of dementia in

diabetes mellitus: a systematic review, Lancet Neurol, 5, 64-74, 2006.

Bredt, DS, Endogenous nitric oxide synthesis: biological functions and pathophysiology, Free

Radic Res, 31, 577–596, 1999.

Calabrese, V, Butterfield, DA, Scapagnini, G, Stella, AM and Maines, MD, Redox regulation

of heat shock protein expression by signaling involving nitric oxide and carbon

monoxide: relevance to brain aging, neurodegenerative disorders, and longevity,

Antioxid Redox Signal, 8, 444–477, 2006.

Guix, FX, Uribesalgo, I, Coma, M and Munoz, FJ, The physiology and pathophysiology of

nitric oxide in the brain, Prog Neurobiol, 76, 126–152, 2005.

Henningsson, R and Lundquist, I, Arginine-induced insulin release is decreased and glucagon

increased in parallel with islet NO production, Am J Physiol, 275, 500-506, 1998.

Hirsch, EC and Hunot, S, Nitric oxide, glial cells and neuronal degeneration in parkinsonism,

Trends Pharmacol Sci. 21, 163-165, 2000.

Iadecola, C, Bright and dark sides of nitric oxide in ischemic brain injury, Trends Neurosci,

20, 132-139, 1997.

Kingwell, BA, Formosa, M, Muhlmann, M, Bradley, SJ and McConell, GK, Nitric oxide

synthase inhibition reduces glucose uptake during exercise in individuals with Type 2

diabetes more than in control subjects, Diabetes, 51, 2572–2580, 2002.

Kroncke, KD, Kolb-Bachofen, V, Berschick, B, Burkart, V and Kolb, H, Activated

macrophages kill pancreatic syngeneic islet cells via arginine-dependent nitric oxide

generation, Biochem Biophy Res Comm, 175, 752-758, 1991.

Kumar, PJ and Clark, M, Textbook of Clinical Medicine. Pub: Saunders (London), 1099-

1121, 2002.
Mankovsky, BN, Metzger, BE, Molitch, ME and Biller, J, Cerebrovascular disorders in

patients with diabetes mellitus, J Diabetes Complications, 10, 228–242, 1996.

Manschot, SM, Biessels, GJ, de Valk, H, Algra, A, Rutten, GE, van der Grond, J, Kappelle,

LJ, Utrecht Diabetic Encephalopathy Study Group. Metabolic and vascular

determinants of impaired cognitive performance and abnormalities on brain magnetic

resonance imaging in patients with type 2 diabetes, Diabetologia, 50, 2388–2397, 2007.

Mastrocola, R, Restivo, F, Vercellinato, I, Danni, O, Brignardello, E, Aragno, M, Boccuzzi,

G, Oxidative and nitrosative stress in brain mitochondria of diabetic rats, J Endocrinol,

187, 37–44, 2005.

Pacher, P, Beckman, JS and Liaudet, L, Nitric oxide and peroxynitrite in health and disease,

Physiol Rev, 87, 315–424, 2007.

Panagiotidis, G and Stenstrom, A and Lundquist, I, In vivo action of cyclic AMP modulating

secretagogues on islet monoamine oxidase activity and insulin release, Endocrine, 2,

571-576, 1994.

Richa, R and Chaturvedi, CM, Effect of endogenous and exogenous nitric oxide induced

alterations in pancreatic architecture via oxidative stress in female mouse, Mus

musculus, International Journal of Innovative Research in Science, Engineering and

Technology, 4, 1333-1343.

Salehi, A, Abaraviciene, SM, Feltstrom, JJ, ran O stenson, C, Efendic, S and Lundquist, I,

Excessive islet NO generation in Type 2 diabetic GK rats coincides with abnormal

hormone secretion and is counteracted by GLP-1, Plosone, 3, 2165, 2008.

Schmidt, HHHW, Warner, TD, Ishii, K, Sheng, H, Murad, F, Insulin secretion from

pancreatic β- cells caused by L-arginine-derived nitrogen oxides, Science, 255, 721–

723, 1992.
Tessari, P, Cecchet, D, Cosma, A, Vettore, M, Coracina, A, Millioni, R, Iori, E, Puricelli, L,

Avogaro, A and Vedovato, M, Nitric oxide synthesis is reduced in subjects with Type

2 diabetes and nephropathy, Diabetes, 59, 2152–2159, 2010.

Valko, M, Leibfritz, D, Moncol, J, Cronin, MT, Mazur, M, Telser, J, Free radicals and

antioxidants in normal physiological functions and human disease, Int J Biochem Cell

Biol, 39, 44–84, 2007.

van Elderen, SGC, de Roos, A, de Craen, AJM, Westendorp, RGJ, Blauw, GJ, Jukema, JW,

Bollen, ELEM, Middelkoop, HAM, van Buchem, MA and van der Grond, J,

Progression of brain atrophy and cognitive decline in diabetes mellitus, Neurology, 75,

997–1002, 2010.

van Harten, B, de Leeuw, FE, Weinstein, HC, Scheltens, P, Biessels, GJ, Brain imaging in

patients with diabetes- a systematic review, Diabetes Care, 29, 2539–2548, 2006.

Weyer, C, Bogardus, C, Mott, DM and Pratley, RE, The natural history of insulin secretory

dysfunction and insulin resistance in the pathogenesis of type 2 diabetes mellitus, J Clin

Invest, 104, 787–94, 1999.