umschl_dialog_plus_6s_gb.qxd 30.09.

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Potential through individuality

Dialog with the future

Hemodialysis

The ABPM Option

The automatic blood pressure measurement or ABPM option
ensures dependable monitoring of your patients. Automatically,
accurately and non-invasively, Dialog+ measures blood pressure
using the oscillometric method. This takes a burden off the staff
and enhances safety for your patients.
The benefits of the ABPM option
n Easy BP measurement at all times – before, during and after
dialysis
n Automatic readings at regular intervals
n BP and pulse rate are clearly displayed on the main screen
n Alarm limits can be individually adapted to patient's blood
pressure by pressing a button
n Selectable color display for blood pressure and pulse curves
n Real-time documentation of all readings It is important that all features and
n Automatic cuff inflation adjustment
accessories fit …
… I want to be able to leverage my options – now and in the future.

Dialysis fluid filter option Option HDF Online

The dialysis fluid filter option is used to significantly improve the
quality and purity of the dialysis fluid delivered by the dialysis
machine. In an additional filtration stage, the dialysis fluid is
pumped through the Diacap® Ultra dialysis fluid filter to filter
and absorb any microbial impurities from the dialysate.
Obviously, treatment with ultrapure dialysis fluid has clinical
advantages. Chronic inflammatory processes triggered by
pyrogen impurities (cytokine-induced formation of interleukin,
TNF, ␤2-microglobulin amyloidosis etc.) are markedly reduced.
This reduction is associated with a positive effect on the pati-
ent's general, nutritional and cardiovascular status.
The dialysis fluid filter option lets you significantly improve the
quality of the dialysis treatment. Consequently, you promote
patient's health and extend their life expectancy. At the same
time, you achieve a high savings potential by preventing against
likely complications and the consequential costs associated with
them.
Hemodialysis
With the Dialog+ Online version, you can carry out high-volume
hemodiafiltration with substitution solutions manufactured by
the dialysis machine online. The solution is made from the
dialysis fluid that is put through an additional 2-stage filtration
cycle run through two sequentially connected Diacap® Ultra
dialysis fluid filters.
Combining diffusive and convective clearance improves the
elimination of small and medium-sized molecules. Likewise, HDF
Efficient processes. Innovative therapies.
Online is also suitable for patients with unstable cardiovascular
Streamlining workflows.
status who tend to experience a strong drop in blood pressure
even at low ultrafiltration volumes.

B. Braun Medizintechnologie GmbH

Schwarzenberger Weg 73-79
34212 Melsungen
Germany
Tel +49(0) 56 61 71-3716
Fax +49(0) 56 61 75-3716
W. 02.10.08/2 No. 708 0075A Edition: 10/2008 www.bbraun-dialysis.com
Dialog_engl_aussen_copy.qxd 06.06.2007 8:01 Uhr Seite 2

Sharing Expertise The synergies of integrated systems Sophisticated communications

Hemodialysis

Dialog+ – Evolutionizing hemodialysis The innovative solutions from B. Braun are synonymous with Our customers benefit from a full-range of services including
excellent medical care and streamlined clinical routines. Our technical support, process advice, business management, consulting,
Driven by our motto, “Sharing Expertise”, we have always customers acquire integrated systems designed with perfectly planning, development, installation and training courses – all backed
maintained a worldwide dialog with our customers, partners and coordinated components. by the vast expertise of one of world's largest medical products
medical researchers. That's why we named our latest and most companies.
innovative hemodialysis system Dialog+. Our mission is to develop
solutions that not only sustainably improve, but also evolutionize
healthcare. Excellent communication and visionary thinking are Nexadia®: This innovative data Concentrates: B. Braun
needed if we want to move forward in our evolutionary development. management solution stream- produces a wide range of liquid
Dialog+ – The original from B. Braun lines workflows - sustainably. All acidic and alkaline bicarbonate-
patient- and treatment-related buffered hemodialysis
data, equipment settings and concentrates for personalized
other relevant information are treatment regimens. The
compiled, consolidated and Sol-Cart B® cartridge containing
stored. For the ultimate in sodium hydrogen carbonate
process efficiency. powder is just one practical
alternative for users.
Needles: Needlestick preventi-
Diacap® ␣ Polysulfone:
on in dialysis is gaining ever
The new dialyzer generation of
more importance. With the
polysulfone fibers meets the
development of new needles for
specific requirements of the
extracorporeal blood treatment,
most complex of regimens
we are doing justice to this
ranging up to and including
need. The Diacan® S safety
efficient high-flux hemodiafil-
B. Braun – A visionary on the healthcare market Decades of dialysis innovations needle with an integrated
tration.
Dialog+ was developed from a synergy of expertise and heritage For decades, B. Braun has been improving the life of dialysis pati- safety clip provides effective
by one of the leading corporations on the healthcare market. ents around the globe with its innovative products and protection.
Backed by a 166-year history of industrial innovations and power, dependable services. For example, back in 1982, B. Braun intro- A/V systems: Bloodline Catheters: Haemocat® Signo,
the company's well-balanced portfolio is stocked with over duced the HD 105, the first hemodialysis machine that measured systems made of biocompatible, the catheter for extracorporeal
30,000 products that are sold in 50 countries on all 5 continents. ultrafiltration both up- and downstream from the dialyzer. This proven and innovative blood treatment, offers users
Over 32,000 employees work for the B. Braun group globally. technology enabled an improvement in dialysis safety. Twelve plasticizer-free components the option of EKG-guided
It is they who have made a major contribution to its success: years later, the Dialog dialysis machine, the predecessor to are the lifeline between pati- catheter positioning. This A dialog ... The result is
In 2006, corporate revenues exceeded three billion euros. Dialog+, was the first to feature convenient touch screen operation. ent and dialyzer. means simplicity with
These are just two notable examples of how B. Braun's visions maximum safety.
... only makes sense if it leads to better understanding. With ■ Sustainability based on future-proof
Corporate structure: Structured competency Dialog+, we at B. Braun have proven how much we understand
have been shaping the future of extracorporeal blood treatment. the process of dialysis, the constraints of the market, the
concepts
The group is organized into four divisions. Each division's
Dialog+ embodies integration demands of our customers and needs of our patients.
■ Efficient work through automation and
products and services address different areas of medicine and
therapy. B. Braun Avitum develops and manufactures systems for Today, with Dialog+, B. Braun is again raising the bar in the field Solutions: B. Braun was the Dialysis centers: B. Braun networking
extracorporeal blood treatment and operates dialysis centers in of hemodialysis. In Dialog+, intelligent software is perfectly first manufacturer in Germany Avitum never loses sight of its
Europe, Asia and Africa. Hospital Care is an innovative developer integrated into sophisticated high-grade, hardware-equipped to develop bicarbonate- commitment to practical appli- ■ Maturity of experience and proven
of product and service concepts for hospitals. Out Patient Market original accessories. As with every one of our products, every buffered hemofiltration cation and patient proximity – solutions
(OPM) provides solutions for private medical practices and the purchase is backed by excellent service support and dependable solutions. That this benefits just one of the reasons why we
homecare market. Aesculap specializes in surgical core processes. global logistics. When you acquire the world's most advanced patients by reducing operate dialysis centers in ■ Quality assurance through smart technology
The expertise of these four divisions is bundled into a competent hemodialysis system, you are buying the embodiment of our cardiovascular complications Europe, Asia and Africa. At
whole. B. Braun, a global corporation that unites convincing corporate values: innovation, efficiency and sustainability. has been proven in clinical B. Braun Avitum centers, dialysis ■ Innovation created together with our
performance with competent leadership. B. Braun. More than Invest in the future. Invest in Dialog+ – The original from B. Braun. studies. patients receive the highest
the sum of its parts. customers
level of healthcare worldwide.
Dialog_engl_innen_copy.qxd 06.06.2007 7:56 Uhr Seite 1

Communication is the concept:

Hemodialysis

The concept of multidimensional communications has become

a clinical reality: The Dialog+ hemodialysis system harnesses
breakthrough technology for more effective therapy on every level.
The most communicative dimension of Dialog+ is its outstanding
network compatibility. Created to interface with Nexadia®
advanced data management software, the centralized
bidirectional network monitors treatment safely and reliably
from start to finish. Therapeutic regimens are logically integrated
in administrative processes. Nexadia® ensures that quality
assurance and reliable verification meet both current and future
requirements.

Dialog+ – Interactive functionality

The design of the Dialog+ hemodialysis machine brings sophisti-
cated medical technology into detailed balance. Its form follows
ergonomic function. All components on the front panel are
arranged in a practical way to facilitate user interaction and allow
the operator to adapt readily to changing therapeutic procedures.
Ergonomic
Lightweight yet sturdy, agile yet on a solid footing, Dialog+ with
its swivel wheels offers the practical mobility needed for every-
day routine. The high-resolution, swivelable 15" TFT monitor is
extremely user friendly, allowing the information to be easily
read from any position and in all lighting conditions.
Functional
The menu navigation is straightforward and takes the diversity of
dialysis routine into account. The clear touch screen facilitates fast
and easy handling. Self-explanatory symbols and understandable
user guidance make operation easier for less experienced operators.
Practical
Thanks to the standard-equipped treatment status color
indicator, operators can reassure themselves, even from a
distance, that the dialysis routine is running smoothly.
Dialog+– Ergonomic, functional and practical technology for
safe and efficient dialysis.
Dialog_engl_innen_copy.qxd 06.06.2007 7:56 Uhr Seite 2
– Optimizing workflows
Nexadia® – Communicating with the future
Nexadia® is your direct link to all the options the future has to
offer. Studies have shown that significant improvements in
workflows 1 and more effective utilization of resources can be
achieved with the Dialog+ hemodialysis system's upgradeable
bidirectional interface to Nexadia® data management software.
Its multidimensional communications concept also supports
optimal quality management. The machine can be preset using
Nexadia® and the chip card. This saves time, which the staff
profits from daily.
Slash operating costs
Uniting economy and ecology, Dialog+ can be programmed to
automatically activate the stand-by mode. This setting cuts back
on water, concentrate volume and electricity consumption. The
auto-priming function saves saline solution during online HDF
hemodiafiltration. Diacap® Ultra dialysis fluid filters have an
above-average lifetime of up to 150 treatments or approx. 900
hours. That translates into significantly lower overhead costs.
All Dialog+ machines have an integrated technical service and
maintenance mode (TSM) for simplified troubleshooting and
documentation. That converts to lower service and maintenance
costs. The customized configurations possible with the TSM
mode additionally allow you to sustainably optimize the
processes at your center. All of these features add up to long-
term cost savings.
Thinking about tomorrow …
… before tomorrow comes. The ongoing dialog with our customers
has shown that keeping overhead costs low has never been more
important. Nowadays, everybody is seeking affordable solutions
that do not jeopardize the quality of care. Because Dialog+
hemodialysis systems are so efficient to operate, they amortize
themselves very quickly. Intelligent upgrade options ensure that
your purchase will be a secure and intelligent investment now
and in the future.
B. Braun has designed Dialog+ and Nexadia® to meet the broad
variety of challenges arising during everyday dialysis routine. The
modular design incorporates many advanced functional options
and an array of practical configurations. B. Braun also continues
to work on further evolving the Dialog+ concept to make each
new feature and accessory even more economical and keep it
ahead of the times. Dialog+ is an investment in the future.
Automatic functions – Less is more
Effortless and trouble-free. That would be one way to describe
day-to-day hemodialysis with Dialog+. The broad range of auto-
matic functions substantially minimizes the time and labor the
staff needs for routine processes.
For example, Dialog+ runs procedures like start-up tests and
weekly disinfection cycles automatically. Moreover, the hemo-
dialysis system detects the patient's blood in the A/V line and,
if required, automatically delivers the preset heparin bolus.
1
D. Osterkorn, "Networking for success in dialysis centers: A prospective comparative
analysis" Gesundheitsökonomie & Qualitätsmanagement; 11: 112-115
Dialog_engl_innen_copy.qxd 06.06.2007 7:56 Uhr Seite 3

Economy meets sustainability

Hemodialysis

Cost pressure is mounting, …

… to provide the best medical care at the most cost-efficient
price. This tenet is the benchmark that will keep dialysis
centers economically viable in the future.

The benefits of an ongoing dialog

■ Automation accelerates workflows and
cuts overheads
■ Minimized water, energy and concentrate
consumption lowers operating costs
■ Individually configurable to center-specific
processes
■ Nexadia® data management software for
process optimization
Dialog_engl_innen_copy.qxd 06.06.2007 7:56 Uhr Seite 4

– Your clinical assistant

Greater proximity to the patient ...

… is sometimes achieved by more technology. This may sound
paradoxical, but where time is money, pre-programmed routines
and automation can leave caregivers free to devote more
personal attention to their patients. Handling simplicity is also
important when it comes to reacting as safely and quickly as
clinical routine demands.

Card reader for faster settings

The Dialog+ Therapy Card minimizes the manual entry of patient
data. Dialog+ quickly scans the personalized settings with the Card
Reader and automatically sets all treatment parameters. Centers
that choose to utilize the advanced Nexadia® data management
system with all its potential options can alternatively download
data with a Nexadia® chip card.
Programmable disinfection with automatic
documentation
For disinfection, Dialog+ is equipped with two unique, mutually
supportive functions. One, the weekly disinfection routine, can be
used to program and store two disinfection cycles per day. The
other, a comprehensive disinfection history, ensures quality
management without added outlay for documentation.
The menu navigation on Dialog+ virtually eliminates errors
altogether: After important data is entered, the user just has to
confirm with the enter key to avoid errors. In all
operating phases, the online help functions support
the operator with plain language prompts and
instructions. These features make it easy for the healthcare staff
to react the instant an alarm sounds and undertake corrective
measures, with confidence and no hesitation.
The use of the Event Timer helps to remind the operator, for
example, to administer a specific drug or deliver a bolus of
heparin. The Event Timer ensures that nothing gets forgotten in
a busy working environment.
Dialog+ – Technology serving users and patients.

Technical updates made simple and effective

Upgrading Dialog+ software is easy with a USB stick and memory
card. The USB stick can also be used for storing and analyzing
equipment data and the trends of previous treatments. Trouble-
shooting has also been simplified. With the integrated technical
service and maintenance mode (TSM), the profiles on all variables
and settings of previous treatments can be graphically displayed
and evaluated. Individualized combinations of settings can be
selected to ensure optimized handling and servicing.

Error-minimizing technology
Intuitively understandable: The Dialog+ touch screen is structured
around self-explanatory 3D icons. This is another positive
dimension that gives users a greater sense of operating security
because they know they can react fast to all therapeutic events.
The learning curve for new staff is short, making it easy for them
to operate the machine confidently on their own.
Dialog_engl_innen_copy.qxd 06.06.2007 7:56 Uhr Seite 5

Intuition meets high-tech

Hemodialysis

Devoting more care to patients ...

… and expending less outlay on documentation. Less
administration means the staff has more time to devote to
personal attention. The biggest advance in hemodialysis
has been to create a greater proximity to the patient.

Dialog+ – Benefits
■ Ergonomic design for simplified handling
■ Quicker therapy induction and
less paper work
■ User-friendly operator guidance
■ Straightforward menu navigation creates
user confidence
■ Simplified priming and disinfection
Dialog_engl_innen_copy.qxd 06.06.2007 7:56 Uhr Seite 6
– Your quality manager
Top quality management …
... that can be feasibly implemented in daily routine is a critical
factor for today's and tomorrow's customers. The intelligent
technology and logical safety concept built into Dialog+ are
synonymous with quality management, added value and low
overhead costs.
Multi-level safety concept reduces risk
The unique, multidimensional safety concept on Dialog+ proves
that ultimate safety, country- and user-specific customization
and personalized therapy are not contradictions in terms. This
balance between minimum risk and maximum flexibility is
achieved in many ways, for example, through the bi-channel
hard- and software safety system, and the versatile
configuration options available with the TSM mode.
Added safety features include the no-nonsense system of
prompts and alarms with the integrated help function, which
gives users clear, unmistakable instructions on how to act.
Additionally, Dialog+ is equipped with a well-structured
emergency management system. In the event of an emergency,
the Bypass and Min UF symbols can be activated instantaneously
by simply pressing a button. If the patient experiences a
hypotensive episode, the bolus function delivers an automatic
bolus infusion – fast and trouble-free.
Other preventive risk reduction functions include the automatic
dialyzer inlet pressure (PBE) monitoring for secondary
membrane formation in the dialyzer and the early detection of
filter clotting and kinks in the bloodlines that prompt the
initiation of appropriate hemolysis prophylaxis.
Patient-personalized dialysis profiles
Effective dialysis treatment must be as individual as each
patient. The software in Dialog+ reacts to each patient's personal
needs. The user can infinitely combine the six different treat-
ment profiles. This function allows ultrafiltration, conductivity,
bicarbonate, dialysis flow rate, temperature and heparin dosing
to be ideally personalized for each patient.
AP VP
Cross-over procedure
Arterial Venous
expansion expansion
chamber chamber
Arterial blood pump Venous blood pump
Dialyzer
Arterial tubing clamp Venous tubing clamp
A variety of options: Three single-needle
procedures
In patients with multimorbidity and vascular problems, the
indication for permanent single-needle (SN) dialysis is being
rendered more and more frequently. Hence, the SN cross-over
feature delivers a continuous SN treatment to achieve the
highest efficiency. With Dialog+, three SN procedures are
possible: SN-KK, SN valve, SN cross-over.
The unique SN cross-over procedure: This pressure-pressure
driven double pump SN system is one of a kind. Compared to
conventional SN systems, it helps maintain continuous blood flow
and relatively constant pressure conditions in the dialyzer.
Operation involves simply setting the blood pump rate and
adjusting the pressure limits. Afterwards, the settings are stored
on Dialog+ therapy cards.
Transparency with Kt/V graphics
As a reliable and no-cost method for monitoring treatment
quality, Dialog+ continually calculates the Kt/V throughout
therapy. The operator automatically receives a graphic display
of the Kt/V profile and an indication about how close it is to
the target. Fluctuations in the predicted curve caused by
changes in variables affecting Kt/V are visible at a glance.
Dialog_engl_innen_copy.qxd 06.06.2007 7:56 Uhr Seite 7

Safety meets flexibility

Hemodialysis

Our patients ...

... trust in us because they know that their safety and security
are paramount. Of course, like everybody else, we have to verify
the quality of our treatments. Modern-day dialysis centers are
becoming subject to ever more stringent regulations for
traceable and transparent quality management. Sophisticated,
high-tech accessories and features make it easier for us to
satisfy all legal and regulatory requirements.

Dialog+ – Benefits
■ Unique safety
concept
■ Mature technology
■ Personalized
therapy
■ Automatic
documentation
Dialog_engl_innen_copy.qxd 06.06.2007 7:57 Uhr Seite 8

– Your systems partner

Process-safety and integrated systems …

… are what our customers have appreciated in B. Braun for deca-
des. From filters and dialysis machines to technical advice, we
offer our contractors the full range of services and products - in
B. Braun branded quality. Our customers know they can rely on
B. Braun's performance. And we always listen and take to heart
what our customers have to say. We maintain an ongoing dialog
with our partners – worldwide.

Because life is full of diversity ... The bioLogic RR® Comfort2 option
… we have equipped Dialog+ with a huge range of customer- This biofeedback system for automatic blood pressure stabilization
specific variants and options. is globally unique. bioLogic RR® Comfort directly measures the
patient's blood pressure and automatically and intelligently
regulates the UF rate according to the principle of fuzzy logic. 3
Option Nexadia® BSL1
The innovative Guideline Technique is based on individual data
With the Nexadia® BSL option, Dialog+ can be linked to the storage and markedly reduces the need for regular blood pressure
innovative Nexadia® data management system. This advanced measurements. Clinical evidence has confirmed that the use of
benchmark information technology supports users and makes bioLogic RR® Comfort 4 leads to a significant reduction in hypo-
their routine work significantly easier. At the same time, this tension-related side effects. The result is enhanced treatment
option improves the quality of dialysis treatments, streamlines comfort for patients and less stress for the nursing staff.
workflows and documents all relevant data. All of which
converts to true savings against mounting cost pressures.
In combination with the Dialog+ hemodialysis machine, the use
of Nexadia® sustainably improves therapy. The operator can use
the screen on the dialysis machine as an input terminal,
supplemental to an external workstation e.g. a Client PC.
Moreover, the bidirectional exchange of text messages, drug
instructions etc. is possible via the message exchange function.

bioLogic RR® Comfort requires virtually no adjustment effort.

1
BSL stands for Bed Side Link, a chip card reader with integrated network functionality.
All the settings required by the medical staff are limited to
This option enables Dialog+ to be run within a network. setting the lower systolic blood pressure limit and the maximum
2
RR stands for Riva-Rocci (the person who, in 1896, invented the original blood pressure UF rate. Beyond this, the Dialog+ screen displays an understand-
apparatus with cuff and mercury pressure gauge, the Riva-Rocci sphygmomanometer, first able graphic at all times. The economical aspects of bioLogic
used to noninvasively measure arterial pressure).
RR® Comfort are similarly compelling. It can be used with just
3
Mancini E, Mambelli E, Irpinia M et al.: Prevention of dialysis hypotension episodes using one blood pressure cuff. That helps save on consequential costs.
fuzzy logic control system. Nephrol Dial Transplant (2007) 22 (5): 1420-1427
4
Roeher O, Schmidt R, et al.: biologicRR Comfort significantly reduces hypotensive episodes
in patients prone to intradialytic hypotension. 38th Congress of the German Society of
Nephrology, Munich, 2007
Dialog_engl_aussen_copy.qxd 06.06.2007 8:01 Uhr Seite 2

Sharing Expertise The synergies of integrated systems Sophisticated communications

Hemodialysis

Dialog+ – Evolutionizing hemodialysis The innovative solutions from B. Braun are synonymous with Our customers benefit from a full-range of services including
excellent medical care and streamlined clinical routines. Our technical support, process advice, business management, consulting,
Driven by our motto, “Sharing Expertise”, we have always customers acquire integrated systems designed with perfectly planning, development, installation and training courses – all backed
maintained a worldwide dialog with our customers, partners and coordinated components. by the vast expertise of one of world's largest medical products
medical researchers. That's why we named our latest and most companies.
innovative hemodialysis system Dialog+. Our mission is to develop
solutions that not only sustainably improve, but also evolutionize
healthcare. Excellent communication and visionary thinking are Nexadia®: This innovative data Concentrates: B. Braun
needed if we want to move forward in our evolutionary development. management solution stream- produces a wide range of liquid
Dialog+ – The original from B. Braun lines workflows - sustainably. All acidic and alkaline bicarbonate-
patient- and treatment-related buffered hemodialysis
data, equipment settings and concentrates for personalized
other relevant information are treatment regimens. The
compiled, consolidated and Sol-Cart B® cartridge containing
stored. For the ultimate in sodium hydrogen carbonate
process efficiency. powder is just one practical
alternative for users.
Needles: Needlestick preventi-
Diacap® ␣ Polysulfone:
on in dialysis is gaining ever
The new dialyzer generation of
more importance. With the
polysulfone fibers meets the
development of new needles for
specific requirements of the
extracorporeal blood treatment,
most complex of regimens
we are doing justice to this
ranging up to and including
need. The Diacan® S safety
efficient high-flux hemodiafil-
B. Braun – A visionary on the healthcare market Decades of dialysis innovations needle with an integrated
tration.
Dialog+ was developed from a synergy of expertise and heritage For decades, B. Braun has been improving the life of dialysis pati- safety clip provides effective
by one of the leading corporations on the healthcare market. ents around the globe with its innovative products and protection.
Backed by a 166-year history of industrial innovations and power, dependable services. For example, back in 1982, B. Braun intro- A/V systems: Bloodline Catheters: Haemocat® Signo,
the company's well-balanced portfolio is stocked with over duced the HD 105, the first hemodialysis machine that measured systems made of biocompatible, the catheter for extracorporeal
30,000 products that are sold in 50 countries on all 5 continents. ultrafiltration both up- and downstream from the dialyzer. This proven and innovative blood treatment, offers users
Over 32,000 employees work for the B. Braun group globally. technology enabled an improvement in dialysis safety. Twelve plasticizer-free components the option of EKG-guided
It is they who have made a major contribution to its success: years later, the Dialog dialysis machine, the predecessor to are the lifeline between pati- catheter positioning. This A dialog ... The result is
In 2006, corporate revenues exceeded three billion euros. Dialog+, was the first to feature convenient touch screen operation. ent and dialyzer. means simplicity with
These are just two notable examples of how B. Braun's visions maximum safety.
... only makes sense if it leads to better understanding. With ■ Sustainability based on future-proof
Corporate structure: Structured competency Dialog+, we at B. Braun have proven how much we understand
have been shaping the future of extracorporeal blood treatment. the process of dialysis, the constraints of the market, the
concepts
The group is organized into four divisions. Each division's
Dialog+ embodies integration demands of our customers and needs of our patients.
■ Efficient work through automation and
products and services address different areas of medicine and
therapy. B. Braun Avitum develops and manufactures systems for Today, with Dialog+, B. Braun is again raising the bar in the field Solutions: B. Braun was the Dialysis centers: B. Braun networking
extracorporeal blood treatment and operates dialysis centers in of hemodialysis. In Dialog+, intelligent software is perfectly first manufacturer in Germany Avitum never loses sight of its
Europe, Asia and Africa. Hospital Care is an innovative developer integrated into sophisticated high-grade, hardware-equipped to develop bicarbonate- commitment to practical appli- ■ Maturity of experience and proven
of product and service concepts for hospitals. Out Patient Market original accessories. As with every one of our products, every buffered hemofiltration cation and patient proximity – solutions
(OPM) provides solutions for private medical practices and the purchase is backed by excellent service support and dependable solutions. That this benefits just one of the reasons why we
homecare market. Aesculap specializes in surgical core processes. global logistics. When you acquire the world's most advanced patients by reducing operate dialysis centers in ■ Quality assurance through smart technology
The expertise of these four divisions is bundled into a competent hemodialysis system, you are buying the embodiment of our cardiovascular complications Europe, Asia and Africa. At
whole. B. Braun, a global corporation that unites convincing corporate values: innovation, efficiency and sustainability. has been proven in clinical B. Braun Avitum centers, dialysis ■ Innovation created together with our
performance with competent leadership. B. Braun. More than Invest in the future. Invest in Dialog+ – The original from B. Braun. studies. patients receive the highest
the sum of its parts. customers
level of healthcare worldwide.
Dialog_engl_aussen_copy.qxd 06.06.2007 8:01 Uhr Seite 2

Sharing Expertise The synergies of integrated systems Sophisticated communications

Hemodialysis

Dialog+ – Evolutionizing hemodialysis The innovative solutions from B. Braun are synonymous with Our customers benefit from a full-range of services including
excellent medical care and streamlined clinical routines. Our technical support, process advice, business management, consulting,
Driven by our motto, “Sharing Expertise”, we have always customers acquire integrated systems designed with perfectly planning, development, installation and training courses – all backed
maintained a worldwide dialog with our customers, partners and coordinated components. by the vast expertise of one of world's largest medical products
medical researchers. That's why we named our latest and most companies.
innovative hemodialysis system Dialog+. Our mission is to develop
solutions that not only sustainably improve, but also evolutionize
healthcare. Excellent communication and visionary thinking are Nexadia®: This innovative data Concentrates: B. Braun
needed if we want to move forward in our evolutionary development. management solution stream- produces a wide range of liquid
Dialog+ – The original from B. Braun lines workflows - sustainably. All acidic and alkaline bicarbonate-
patient- and treatment-related buffered hemodialysis
data, equipment settings and concentrates for personalized
other relevant information are treatment regimens. The
compiled, consolidated and Sol-Cart B® cartridge containing
stored. For the ultimate in sodium hydrogen carbonate
process efficiency. powder is just one practical
alternative for users.
Needles: Needlestick preventi-
Diacap® ␣ Polysulfone:
on in dialysis is gaining ever
The new dialyzer generation of
more importance. With the
polysulfone fibers meets the
development of new needles for
specific requirements of the
extracorporeal blood treatment,
most complex of regimens
we are doing justice to this
ranging up to and including
need. The Diacan® S safety
efficient high-flux hemodiafil-
B. Braun – A visionary on the healthcare market Decades of dialysis innovations needle with an integrated
tration.
Dialog+ was developed from a synergy of expertise and heritage For decades, B. Braun has been improving the life of dialysis pati- safety clip provides effective
by one of the leading corporations on the healthcare market. ents around the globe with its innovative products and protection.
Backed by a 166-year history of industrial innovations and power, dependable services. For example, back in 1982, B. Braun intro- A/V systems: Bloodline Catheters: Haemocat® Signo,
the company's well-balanced portfolio is stocked with over duced the HD 105, the first hemodialysis machine that measured systems made of biocompatible, the catheter for extracorporeal
30,000 products that are sold in 50 countries on all 5 continents. ultrafiltration both up- and downstream from the dialyzer. This proven and innovative blood treatment, offers users
Over 32,000 employees work for the B. Braun group globally. technology enabled an improvement in dialysis safety. Twelve plasticizer-free components the option of EKG-guided
It is they who have made a major contribution to its success: years later, the Dialog dialysis machine, the predecessor to are the lifeline between pati- catheter positioning. This A dialog ... The result is
In 2006, corporate revenues exceeded three billion euros. Dialog+, was the first to feature convenient touch screen operation. ent and dialyzer. means simplicity with
These are just two notable examples of how B. Braun's visions maximum safety.
... only makes sense if it leads to better understanding. With ■ Sustainability based on future-proof
Corporate structure: Structured competency Dialog+, we at B. Braun have proven how much we understand
have been shaping the future of extracorporeal blood treatment. the process of dialysis, the constraints of the market, the
concepts
The group is organized into four divisions. Each division's
Dialog+ embodies integration demands of our customers and needs of our patients.
■ Efficient work through automation and
products and services address different areas of medicine and
therapy. B. Braun Avitum develops and manufactures systems for Today, with Dialog+, B. Braun is again raising the bar in the field Solutions: B. Braun was the Dialysis centers: B. Braun networking
extracorporeal blood treatment and operates dialysis centers in of hemodialysis. In Dialog+, intelligent software is perfectly first manufacturer in Germany Avitum never loses sight of its
Europe, Asia and Africa. Hospital Care is an innovative developer integrated into sophisticated high-grade, hardware-equipped to develop bicarbonate- commitment to practical appli- ■ Maturity of experience and proven
of product and service concepts for hospitals. Out Patient Market original accessories. As with every one of our products, every buffered hemofiltration cation and patient proximity – solutions
(OPM) provides solutions for private medical practices and the purchase is backed by excellent service support and dependable solutions. That this benefits just one of the reasons why we
homecare market. Aesculap specializes in surgical core processes. global logistics. When you acquire the world's most advanced patients by reducing operate dialysis centers in ■ Quality assurance through smart technology
The expertise of these four divisions is bundled into a competent hemodialysis system, you are buying the embodiment of our cardiovascular complications Europe, Asia and Africa. At
whole. B. Braun, a global corporation that unites convincing corporate values: innovation, efficiency and sustainability. has been proven in clinical B. Braun Avitum centers, dialysis ■ Innovation created together with our
performance with competent leadership. B. Braun. More than Invest in the future. Invest in Dialog+ – The original from B. Braun. studies. patients receive the highest
the sum of its parts. customers
level of healthcare worldwide.
umschl_dialog_plus_6s_gb.qxd 30.09.2008 8:55 Uhr Seite 1

Potential through individuality

Dialog with the future

Hemodialysis

The ABPM Option

The automatic blood pressure measurement or ABPM option
ensures dependable monitoring of your patients. Automatically,
accurately and non-invasively, Dialog+ measures blood pressure
using the oscillometric method. This takes a burden off the staff
and enhances safety for your patients.
The benefits of the ABPM option
n Easy BP measurement at all times – before, during and after
dialysis
n Automatic readings at regular intervals
n BP and pulse rate are clearly displayed on the main screen
n Alarm limits can be individually adapted to patient's blood
pressure by pressing a button
n Selectable color display for blood pressure and pulse curves
n Real-time documentation of all readings It is important that all features and
n Automatic cuff inflation adjustment
accessories fit …
… I want to be able to leverage my options – now and in the future.

Dialysis fluid filter option Option HDF Online

The dialysis fluid filter option is used to significantly improve the
quality and purity of the dialysis fluid delivered by the dialysis
machine. In an additional filtration stage, the dialysis fluid is
pumped through the Diacap® Ultra dialysis fluid filter to filter
and absorb any microbial impurities from the dialysate.
Obviously, treatment with ultrapure dialysis fluid has clinical
advantages. Chronic inflammatory processes triggered by
pyrogen impurities (cytokine-induced formation of interleukin,
TNF, ␤2-microglobulin amyloidosis etc.) are markedly reduced.
This reduction is associated with a positive effect on the pati-
ent's general, nutritional and cardiovascular status.
The dialysis fluid filter option lets you significantly improve the
quality of the dialysis treatment. Consequently, you promote
patient's health and extend their life expectancy. At the same
time, you achieve a high savings potential by preventing against
likely complications and the consequential costs associated with
them.
Hemodialysis
With the Dialog+ Online version, you can carry out high-volume
hemodiafiltration with substitution solutions manufactured by
the dialysis machine online. The solution is made from the
dialysis fluid that is put through an additional 2-stage filtration
cycle run through two sequentially connected Diacap® Ultra
dialysis fluid filters.
Combining diffusive and convective clearance improves the
elimination of small and medium-sized molecules. Likewise, HDF
Efficient processes. Innovative therapies.
Online is also suitable for patients with unstable cardiovascular
Streamlining workflows.
status who tend to experience a strong drop in blood pressure
even at low ultrafiltration volumes.

B. Braun Medizintechnologie GmbH

Schwarzenberger Weg 73-79
34212 Melsungen
Germany
Tel +49(0) 56 61 71-3716
Fax +49(0) 56 61 75-3716
W. 02.10.08/2 No. 708 0075A Edition: 10/2008 www.bbraun-dialysis.com
umschl_dialog_plus_6s_gb.qxd 08.10.2008 12:01 Uhr Seite 1

Potential through individuality

Dialog with the future

Hemodialysis

The ABPM Option

The automatic blood pressure measurement or ABPM option
ensures dependable monitoring of your patients. Automatically,
accurately and non-invasively, Dialog+ measures blood pressure
using the oscillometric method. This takes a burden off the staff
and enhances safety for your patients.
The benefits of the ABPM option
n Easy BP measurement at all times – before, during and after
dialysis
n Automatic readings at regular intervals
n BP and pulse rate are clearly displayed on the main screen
n Alarm limits can be individually adapted to patient's blood
pressure by pressing a button
n Selectable color display for blood pressure and pulse curves
n Real-time documentation of all readings It is important that all features and
n Automatic cuff inflation adjustment
accessories fit …
… I want to be able to leverage my options – now and in the future.

Dialysis fluid filter option Option HDF Online

Hemodialysis
The dialysis fluid filter option is used to significantly improve the With the Dialog+ Online version, you can carry out high-volume
quality and purity of the dialysis fluid delivered by the dialysis hemodiafiltration with substitution solutions manufactured by
machine. In an additional filtration stage, the dialysis fluid is the dialysis machine online. The solution is made from the
pumped through the Diacap® Ultra dialysis fluid filter to filter dialysis fluid that is put through an additional 2-stage filtration
and absorb any microbial impurities from the dialysate. cycle run through two sequentially connected Diacap® Ultra
dialysis fluid filters.
Obviously, treatment with ultrapure dialysis fluid has clinical
advantages. Chronic inflammatory processes triggered by Combining diffusive and convective clearance improves the
pyrogen impurities (cytokine-induced formation of interleukin, elimination of small and medium-sized molecules. Likewise, HDF
Efficient processes. Innovative therapies.
TNF, ␤2-microglobulin amyloidosis etc.) are markedly reduced. Online is also suitable for patients with unstable cardiovascular
Streamlining workflows.
This reduction is associated with a positive effect on the pati- status who tend to experience a strong drop in blood pressure
ent's general, nutritional and cardiovascular status. even at low ultrafiltration volumes.
The dialysis fluid filter option lets you significantly improve the
quality of the dialysis treatment. Consequently, you promote
patient's health and extend their life expectancy. At the same
time, you achieve a high savings potential by preventing against
likely complications and the consequential costs associated with
them.
B. Braun Avitum AG
Schwarzenberger Weg 73–79
34212 Melsungen
Germany
Tel +49 (56 61) 71-26 24
Fax +49 (56 61) 75-26 24
e-mail: dialysis@bbraun.com
W. 01.10.08/2 No. 708 0075A Edition: 10/2008 www.bbraun-dialysis.com