Om 4 urs klausimal Cukrinio diabeto komplikacjos y [rma of 1. diabetic Qiypergyeaemic) Ketoacidos & diabetes 2. Hypoplyeaemie coma 3, hyperlactaidemic coma 4 hyperosmolar coma Df ® eR Duneral weakness 7 ketoacidosis symptoms (name atleast Polsuria. 3 gmptoms) polilipsia ‘Nausea , vomiting (adomtinal pai (often in younger patients) 3. Diabet (hyperalyesemioy I sluggishness — —T5¢ NM ketoacidosis symptoms (name at least | (CQ Drysskinvand mucous membranes (| 3 signs) B__Kussmaul breathing @ Tashyeartia | Zkussmauls breahing Syaptoms | F — Far = ZRhythmic acy ney whores Vi 1. | Diabetic (hyperglycaemic) a ‘estoaidose ets Ketones in the blond or urine . - Blood pH <7.3— metabolic. cxcatesti- 7 Gay | Diabetic (hyperglyescmic) 7, Comeation of@ehsnation ‘Ketoeidosis tesiment principles ( coneet ramed by order) 5. eortestion o A Si ase cometon sd pl <6 3. Hypeslyesenie coma Sympioms acne ea _ | aera Hemor lei one 3 Sweeny is L . shel 7) Cascio oe Raf 7 Easy (ool games alos Ca) - ear ees of ger rs on ea oa miv ctor, g/mol 2tx 5. | festaid treatment of Severe hypoglycemia, cca Amy nl eye Layee a b-9 10 = Ze oss doves ml ghore Slat BO6 & When shold you suspect ler patents wih Iyperosmolar condion? ‘resiment with oa Thame at east signs) Hyperglyoonia > 33 mmol T s ; there [esteremicn hacbie aadsis Phere is nasevidence of ketoacidosis ‘Accompanying comorbidity (infos process, © ne kelrntien fewtatacl siete, panei) oF [elloty Seu dehy (Lic EEE, 7s mttaer Diabetic rinopl, newOpay: Rep | ‘complications pod | Diabetio macrovaseu ‘Rehan caniovascular disease —CNSTEUPTEED| complain Cigna | shemiversbroasardinewe 9, | Target HATE in Lithuania WATE SOR sontza) tobod ra] The. contr. 2 3] 4 1 TS a 7 ST fuces lame lest ions in ao 4 T. Noma diabetic retinopathy 2 Prprlierating diabetic retinopathy 5. daet nay Diabetic maculopathy 16 | When tore ape dels patent” wer bss has bese dagnoned to anophihalmologist? (7) TF.) Wien oer ape ables paves | HIE er Tabs as bee diagonal to an ophthalmologist? 18, | nephropathy? ‘What i an gary sign of dios | MigaTbuminaria (30 (mapa val) 15 [aR meseaoninara | ZOO mg 20, | How many times should albumin in | Tass times, vo ofghighleyaed albumin willbe Tse in tern e monte fe foun ‘What ests areeariod gut to as in diabetic GrnUrea nm or, \ 22, | Group of drugs that act primarily on or BRE s relcung disheie nephrpathy - } ‘23. | Diabetic neuropathy classification (localized ) neuropathy ‘eo “onl cabamic ———=. -reigccucpeif eine Comm | RE neeraky es reunepatty Ti Sady (at pients boltie), wich | ORonats ood pears meauraneat 7 JA thant be eo ov ion of ‘utononis neuropathy, 25, | a cused by sensory neuropathy? | risk of legaton of EEE WY Clinically significant autonomic Cardiovascular ‘neuropathy lesions of intestinal oy Eiernary . — — NYA) 27. | Seg amputation ik determinants of |(Remopati hes infetion WA labs litus FE, | What heals achat (Doppler | Syste Wood prewar at adonae pes oF Index tibialis posterior and aati aia v 25, | fesdone to confi the diagnosis oF wl ‘neon sent ES eo, PF 30, | When does leg angiography need ‘Whey ec £S)~ be done? QB tus LO Of Bloal_fresuHe ct tre anidle © He Bicol Pestue In He Upper arm. LD Egor weeDiabetes Melitus treatment FINAL Evalda Egle Eil Nr Klausimas ‘Atsakymas Kotial geriamyjyantidiabetiny vaisty gru i priklguso Metforminas? Which oral anidabetic medication Metfor- min belongs to @ graup? Mad © —_ a Prieé kok tyrima ir po jo reiki lakinal nx traukt! metformino vartojima ir Kode? Before any investigation and after tempora- ily withhold metformin and why? Bator shih text cy ater vrebrectin, omnes} Grou Le SOR”, rie bet kur radologinjodo Kontrastin) ‘prima ir po jo ~ gai pablogint inks fnk- cia, suklt latacingacidace, Before ' and may ‘ = on Kontraindikacios Metformino skyrimut CContraindications for metformin eee Inksty funkeios nepakankamumas (GFG60mI/min) Galinéos salygothipoksija bokles (apsinuodifimas, anemia, plavcy- liges ark.) -Kepen funkejos nepakankamumas Didetio laipsnio, amus sirdies nep- -enkarumes fnoec ooenc ame” emi, Mere 3 4Diabetes Melitus treatment FINAL Evalda Egle ‘Biguanidy veikimo mechanizmas (3) Biguanides mechanism (3) 4 cooalin, gersemurhy (Gplesrme geese coments! [Parcrrecyores_w lver sh | 90 y Rgtucaee waprerer LMWH 1. Maina kepeny gluhoztsgamyb, Hopi likonogenes fit. senolcg 2, Didinajaurmg nsdn ere lakes pestsvinimas rpaaudo- jimas perYerintuose audininose 8 Letina glukses passat maizarnyno. Decreases hepatic icose production by ini hasan ong gngenatsis Didinajautrums insulin, Improving gluco- 'e uptake and utiizaton In peripheral tissues ‘Slows glucose maiézamyno of appro- priation. Kokiu geriaruju antighabetniy vosty gr pes matin rezistentiskurn insulin? Which oral antidiabetic group reduces insu Uincesistance? Biguanidal,tiazolidinedionai | ‘vardnkte 3 sulfonlharbamidypreparts, da icsianaejaqns CD sxchm Lis the 3 he most commonly aed inte treatment of CD Giiicidas, glimepiride, lps, gividonas Gliclacite, glimepiride, eid, gions ontraindikacijos sulfonitkarbamidy skyrimui \isvardinkite bent keturias) patrgndlcations of uiphonytes st at — fegpeNEy ~ face Liver 2 bea fertave ® Dyyylst ) Rowden Nestumes, Laktaie moses (nfekcinétigo, {raumos, chiurnesintervencioe) 4 Sinks inti ir kepeny fnkesoe repakankamimas lpn? 5, ipo cunrins dabetas (teeton, waums, sus Exlinterventions) ns “Pagrindinis sulfonitkarbamidy po veikis ‘The main effect of the sulfonylureas ‘gina insuno skyrimg Kokiy geriamyjy antidiabetiniy vaisty gru pes didina Insulin skyrima? ‘Sulfonikarbamidai, einai, GLP Sulphonylureasglinidal GLP wir tic rou IBS the ss a Reeeperad alel ha Diabetes Mellitus treatment FINAL Evalda Egle 10 Rhos waiving? -Teas DPP ba Wt rh 0 gogo mie bse on Derbi te een eee BL mei 7H [enna iy is mechs | ce pio Fam eigenen, PES BiplaSnecanim cut” [eds te al of cs ne ue | OPP bores Bots DPP-t inhibitors effect Binaerin penser Sheng al ipetlpptace-4)DPP-A) i prin en- ‘dogenniy mbsing king 1. | Prin mechanzneh no are pritiwo | nolo i glkagono selrcia glagono sakes homeonae pros toro wey "The man mechanioms tha aft glucose homes ond "H.| Kia kardovatline poole yr Konrad | Nastya res nepalankenmas or Hes eta piogttazono syria eatin nef NYELA LIT ‘What's cardovasalar diese i contrandtg- {ion for plogltazone appoinonent? Th and a nistervleehear 0) (NYHA class HIV) 15. | Kok Sot era mal oid ta, pri us aniazolidine ony raped?” Resins "hat you know oral andes depends taza inedione grow? CC2O f 16. | aip vino dame iran harmon, okt ( glakagonqpanaies ppd rin svarbig king pluhozeshomeasace?1- eth portant sca hmgosasts? Enumerate hen guise hernoasiag( (GLP-1) 1 gstroitestnais pptas (GIP) Seer ere LP TF | Kode grea cudynio daber kool, slant GLP-iir DPP-t grupos prawns yisus? Why improves dabetes contol tthe GLP-L an Pat drugs belonging tthe gross? ‘Skatinamagliakagonosupresiiarinsalinsohrci. lie | “Kolas gripes geriamwasasanidiaboininsvis- tu dabatinkadernt brit DP al. ‘ha group of oral anidabai drugs mos su bajo combining onthe DPP-4inhibitor?Diabetes Malus weatment FINAL EvalaEGIe 155...) Wberene en: 720 = fre! é 1 Pirmasis DPP-+ inhibitory grapel prikawants ‘its pradtan rat 2 po CD gycha First of DPP-4 inhibitors member drug trod. ced in the Weament ge? aabetes joe ‘Ar DPP-tnhibioriasgulomas Tipo CD? 1s itpossible DP inhibitors o pet pe I dio. ete? Diepelomar Unread YE 2h | Koknstinore DPP-+4 inhibitory rape prio nis meitomentes? then {ou know what the DEP-4 obo belonging to aeaeeeee mere ‘Shgliptnas, Saksagipinas 2 pe] e “Kaa reiki matin Sg gant rin dob Gansd RRL Gl fein When the nee to reduce the dose of sitagliptn in the treatment of diabetes? (GLP-1velkimo mechantzmal GLP} mechanism of ation (4) al igyuln Secteur, Tego apendert mamer @ queeS\ppresior Kept qkese ped action Ease. ompsty » etabey, 1.Shatna glukagonosiprsia maja kepeny lakers gamybo, 2 sata inuling sere, Prideusomel mo glikastskoneentracts, Setna mast evakuaig sand, {frcikiatsotama i pet conus pagumbry- |e ede soraman ats petites Kia glomeral recor majo ‘omtmin Narechite GLP-1 vary grup pitas Choosing GLP-1 drug growp, the mene Bscnatidas raga, Eissentdavar ht) lepeiite iatie,isisenatias, ee) Kolpetiasvor| GLP prdawsantsvastal? How does the weight ofthe GLP-1 belonging to the medicines? Dales matin Sr Sees gm | BES eo ickocing Shock int ‘Kokiw yas rekomenduojama prader yeh 2 ‘ipo eutrin| diaeny? What product is recommended o start the net: <—Ke @ Diabetes Melitus treatment FINAL Evalda Egle > [28 [bias ilo suling sere atin antsy iain Baa nena insutne pompa) Most physotgial insulin secretion con dng fo the gy sn tray ns amp Seton nt iis) agin insulin ines inten ising evap) femmes ete "a ‘Kade 2 tipo CD gydomasinsaliu? When ype 2 diabetes, reament with insulin? BOB tromtes wn eal, ‘season esa urges bi tens nation of the panes condition in argent 30. | Koki po eukrini daben sergantrekomendvo- fre En ans ein eer [ess gat haateer Gy oh 9 Wht os of dts i recowmended csi miceacting ns? aa OST 2 tipo cubriniu dade ‘ype 2aaeter mele ‘Kip shirstomi insulin pagal veikino ig? Hw classified by he fanctioning of lin Tg, the vets ie pepe to) veih into ine hey, tte (ee Why not commonly used nthe neatment of ‘man insu and insu analogues? Wha are the advantages of analog? ten Lang, nermeditcinglomgend short as) peat E02, | Kat doch maja ox | Labo oink og newb ising in ino uno ontop Rote ao verbal? ori wit te solos sc io ae 33. 34 Roa coin = tage te canes shot aduny knee. ontiny Neaof 3D CD diagnostika ir prevencija J ce ar 1. Carini PSO. 1. The defisition of according to the WHO. ito apibresimas pagal etes Iretedbelt disease sbtlaclene Cains diabeis ra metaborniysuvikimy vison, Kars mot stebima ltnéhipeglikemija su angliavandeni, reba i baltymy apykaito surikimais,atsrandant del daugybés paveldimy it insiamy etiolowiniy priezascy,sukelianiyinsulino sekrecjos Infra jo vekimo sutikimus Diabetes melts isa metabolic disorder asa whole that is ‘monitored with chronfe hypersyeemfa of carbohydats, fat and protein metabolism disones arising from a numberof Sd aoquited aetiological factors ous ali seven eo iasulin section and / or alfuntions. 2 Roki oa eke dakes | Gikemyja nevalgis S70" mmoU arb padjus 2 val po 7S ignosinat Kite aieant|gliondskrvio==111 mmol, abu abu teri GTM alikemig. rodmenys | Glcemy (ot xt MG om ‘eninge plazmoje)? i i or “ae 2 Mit we dai al. fr dabei in GIM (gloomy it ‘venous plasma)? MA 3. Kokie yra_gliukoz’s tolerancijos sutrikimo diagnostinii krtenji (likemijy veningie plazmoje)? 0 5. What is hepecose tolerance “Glikemija nevalgius Ge ita) 7.0 mmol ie pragjus2 val. po 738 aliukozés keivio->7.8 ir 11,1 mmol Glucose (aot ested) (if checked) <7.0 mmol /1 and 2 hours. 65] mmol iL. let = fest Qeere THO mmmst gmr of disorder diagnostic ~~ criteria Giyemte aireeinas| core Worse PIF chs plasma)? ca ah aber oa T okie ya AR | OMkonia neal SOT WD mal pa Zw po TSE nevalgius diagnostnial kniteiai (elikemijy rodmenys veningje plazmoje)? 7 What is impaired “glucose Giagnostic _ccitena_(eyeeny in enous pla} eliukozts kravio--<78 moll. Glucose 267 and<7.0 mmol || and 2 hours. after 75 g glucose {oad 28 mmol/L Tee Fasting gljenia PHO 261¢30 EAr_ salina diognozoodoaktah Giahetgradas pikozug puesta kena eplariname kraj? 1s it possible to diagnose diabetes by findings of glycosuria and slevatod bload glucose capil loos? ah 14 gluse ex ‘Ne. J = co © Trumpal apraiykitekalpalickamas G™, 7. Deseribe shorty! glucose toleranse SSL peasy ie ao be of Usont 3 Robie yr nt coke dite CTW alicamas iq (TE val pref méainfnegalina valgoa, emus hau (aikemia ii) bevaliusiam paientu,doodama $Sge 78 glukows iSrpintos 180-300 ml vandns per 5 min, po 120 min vel tama glokows Kekis kaise mevinio metsiD ‘Simpfomai susirgus 1 Spo eokrinia diaborw? ‘What are the typical symptoms of. Pagren's eR Y G w e a es Siipnumas, beadras nuowargis, —mieguistumas, —pablogeies reg8jimas, pangs odosligos, motes vulvovaginita,pykinimas, ‘vémimas, pilvo skausmai,acctono kvapas if burmos, Kusmatlio loegerines, Senos 5. Kokie 72 pik eukrinio dabsto simptomai susrgus 2 tipo eukrniy diabetw? ‘What are the typical symptoms of diabetes develop Type 7 diabetes? padedantys.atskind I ir 2 ipo diabeta? What are the main cites to distinguish type 1 and 2 dfBetes? Samos Vern sere en Gali iti bent vienas | tipo cukrinioGiabetoSmpeomas GToSKUys, «danas. Slapinimasis, svorio krtimas, bends siipnumas, ova), ners ayes, leah gyantys odos sumesimal at injovimai,” ranky ir Koja” tipimas™ bet laioimas” paskartojantios os, danteny "it slapimo tak ‘infkejos el Persistjantis mili gry be ‘here may be at lest ogg bype 1 dabets symptoms (it, ‘weakness, fatigue), Sh slow healing cats oF Bruises on the skin ofthe hande and fect numbness "and" pins and necdles ", recuming skin, gum and trary tat nfton and perssenc yest onus aie ELEY “Amdia, ios cig, Kano stoi, nsiskuninal, ora Ses. Ntoryof the disease, bydeiat, compl, Pereich aye yowery vein inpuerrenh , wernt TT, Ivardinkite 2 tipo _cukrinio ‘iabetorzikos veiksniue (bent 7). List te type 2 diabetes risk factors (at ‘one ~famiy 9 ~ Obes 3 . Gi 10 Omega thiol, poi -byehtin Pacidehi kano mase (KMI=25 Kaimd) ar Hemens apimtis yma > 102 em, motery >88em), cukriniu diabetu serga pirmos eles ‘imints, padidejes arterinis kraujo spaudimas (214090 mH), padidejes wiliceridy 2.2 mmolA infar sumazéjgs DTL<1.0 ‘mmol vyrams ir <1,3 mmol moteims kiekis, mas fzinis aktyvumas, bo ar yra GTS ar SGN, Birdies i krajagysliy igos (kardiomiopatia, ifemine Sedies liga), moterys gimdziusis 4 ke, je didesnius ‘nayjagimius arba srgusios gstacinia diahets, policistniskiusidzy sindromas, akantoze nigricans. Increased body weight (BMI225 kg / m2) or waist circumference (xen 2 102 em for women 288m), diabetes melitus affects fist ‘degree relatives, high blood pressure (2140 / 90 mm), increased trglyeerides>2,2 mmol / and /or low HDL <1,0 mmol /1in men and <3 mmol / in women, low level of physical activity, has ‘been oF is GTS or PGI, cardiovascular disease (cardiomyopathy, ischemic heart disease) women giving a birt o4 kg and higher rnewbom or a history of gestational diabetes, polyeystc ovary syndrome, gkantor® nigricans, 2. Kokie/iyrimal_padeda (veri ‘Cpepido ir insulino (yrimal (nevalgus/po valgio ar GTM). ‘cukriniodiabeto )/"endogeninioinsulino atsrzas? | C=peptie ancinsulintexts (before food / after food or GT. Qf What kind _of research se to Oe ms alvin Kasos saleliy Tasieliyantiktnai, glutamine rigites ckarboksilazés antkinai, inslino "autoantikinai,iozino siagnore? (lvardinti 4-5 tyrimus) {osftazts baltymo anikGna genetinaityrimai GLA),iar eae atin eg 1 diabetes sgtoiogeal diagnosis? 30kg/m2; iakozurjapirmo prenatlinio vizio metu;ankstesiy nest -metu gime Ktdikia, kuriy svoris 4.0; ankstiau nutayta SGN arGTS; ankstesni ncsaiskint persileidimal ar kodikiy apsigimimai (nepalankiakuseriné anamneze);poicstiniy kiusidziy Sindromas; moter, kluisio 8 etniniggrupiy, kur yradidesnis 2 ‘ipo CD daanis; dabartinis GKK naudojimas; vyresnés ne 25m. amdiaus moter: rySki hipertenij a neStumo salygota hipertenzija. CD fanily history (first-degree relatives); gestational diabetes history of previous pregnancies; BMI> 30k /m2;glycosuta rst prenatal visi; previous pregnancies babies weighing 40; previously established PGI arGTS; previous undisclosed ‘miscarriage or birth defects for babies (reproductive history), polveystic ovary syndrome; women come from ethnic groups, Where there is higher incidence of type 2 diabetes; current use of the DCC; older than 25m. Women; bright hypertension or hypertension caused pregsaney. TS. Koka ya pacientiy, sergantig gestacinindiabet, tolimesné {yrimo taktka po giméymo? ‘What i the proportion of patients ‘with gestational diabetes, futher research tates afer giving birth? Po gindymo pradjus 6—12 savaitiy visoms moterims, kurioms ‘buvo diagnozuotas GD, tui but patikslintadiagnozé ailiekant 2val. 758 GTM, ‘Aft 6-12 weeks of bit forall women who have been diegnosed TD, Apibidinkite 2 tipo eukrinio ‘iabotopirmines profilaktikos smctodus (kokisi popula wi used wo the diagnosis Tou T5ECTT.— _ eae. avg asmeny oeaisietgane| Konkrti hast sled informa [vias dais svi mii, iin aliyvumo svat lina! zis