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Not Every Gene Transcribes mRNA

At present time it is commonly known that not every gene transcrines mRNA that will be
translated to procedure polypeptide. It was known that several genes transcribe tRNA, rRNA as
well as snRNA. Those RNA are not translated to produce any polypeptide, although involved
directly in the synthesis of the polypeptide.

There are many genes detected in various organisms functioning to trancribe so many
types of tRNA pairing with the genetic codes related in translation proces. It is estimated too that
there are 60-63 types of the genetic codes (Lewin, 2000). Therefore it is estimated too that there
are 60-63 types of tRNA and the quantity of tRNA genes are likewise.

There are also several genes detected in various organisms functioning to trancribe
rRNA, although its quantity is not so much like the quantity of tRNA gene. For example in
prokaryotic organisms, there are separate genes transcribing 5S rRNA, 16S rRNA, as well as
23srRNA but in mammalian there are also another gene transcribing 5SrRNA, 5.8SrRNA, 18S
rRNA, and 28S rRNA. On the other hand, in eukaryotic organisms there are too several genes
transcribing snRNA.

Review of One Gene Polypeptide Hypothesis

Based on the explanation related to the paradigm of “one-gene-one enzyme hypothesis”


as well as “ one gene one polypeptide hypothesis” discussed before, it is vey clear that the two
paradigms had been formulated at the era in which a gene was interpreted as a continous DNA
sequence. On the other hand, such gene interpretation right now is debatable. Review of one
gene-one polypeptide hypothesis will be carried out within the bounds of the two dimensions.

Tidak Setiap Gen Menranskripsi mRNA


Saat ini sudah umum diketahui bahwa tidak setiap gen mentransplantasikan mRNA yang akan
diterjemahkan ke prosedur polipeptida. Diketahui bahwa beberapa gen mentranskripsikan tRNA,
rRNA serta snRNA. RNA tersebut tidak diterjemahkan untuk menghasilkan polipeptida apa pun,
meskipun terlibat langsung dalam sintesis polipeptida. Ada banyak gen yang terdeteksi di
berbagai organisme berfungsi untuk trancribe begitu banyak jenis tRNA pasangan dengan kode
genetik yang terkait dalam proses terjemahan. Diperkirakan juga bahwa ada 60-63 jenis kode
genetik (Lewin, 2000). Oleh karena itu diperkirakan juga bahwa ada 60-63 jenis tRNA dan
kuantitas gen tRNA juga sama. Ada juga beberapa gen yang terdeteksi di berbagai organisme
yang berfungsi untuk trancribe rRNA, meskipun jumlahnya tidak lebih seperti kuantitas gen
tRNA. Sebagai contoh dalam organisme prokariotik, ada gen terpisah yang mentranskrip 5S
rRNA, 16S rRNA, serta 23srRNA tetapi di mamalia ada gen lain yang mentransendens 5SrRNA,
5.8SrRNA, 18S rRNA, dan 28S rRNA. Di sisi lain, pada organisme eukariotik ada terlalu banyak
gen yang menyalin SNRNA.

Ulasan Hipotesis Satu Hipotesis Gene


Berdasarkan penjelasan yang berkaitan dengan paradigma "satu gen-enzim hipotesis satu" serta
"satu gen satu hipotesis polipeptida" dibahas sebelumnya, itu jelas bahwa kedua paradigma telah
dirumuskan pada era di mana gen diartikan sebagai urutan DNA kontinyu. Di sisi lain,
interpretasi gen seperti itu sekarang masih bisa diperdebatkan. Tinjauan satu polipeptida gen-satu
hipotesis akan dilakukan dalam batas-batas dua dimensi.