PROGRAM EHA2018

Pre-conference cocktail

Wednesday November 7th, 7 PM - 10 PM

Muntpunt Grand Café (next to the Venue), Rue Léopold 2, 1000 Brussels

THURSDAY NOVEMBER 8th

Day chair: Sven Bulterijs
09:00 – 09:45 Registration
09:45 – 10:00 Welcome address

Victor Björk
Director, Heales vzw
1. Extracellular matrix aging
10:00 – 10:20 The mortar between the bricks: Damage to the ECM causes
aging phenotypes

Sven Bulterijs
Heales vzw, Belgium
2. Cellular senescence
10:20 – 10:40 Modulation of the senescence response to delay accelerated
aging in cancer therapy

Marco Demaria
University of Groningen, The Netherlands
European Research Institute for the Biology of Aging, The
Netherlands
10:40 – 11:00 Coffee pause and networking
11:00 – 11:20 Targeting STING in senescence with small-molecule inhibitors

Andrea Ablasser
Swiss Federal Institute of Technology, Switzerland
11:20 – 11:40 Unraveling heterogeneity in cellular senescence to target signs
of aging and cancer

Peter de Keizer
University Medical Center Utrecht, The Netherlands
11:40 – 12:00 A versatile drug delivery system targeting senescent cells

Daniel Muñoz-Espín
University of Cambridge, UK
12:00 – 13:30 Lunch

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13:30 – 14:30 Anti-senescence interventions to improve healthspan in mice
Keynote 1
Thomas von Zglinicki
Newcastle upon Tyne, UK
3. Bioinformatics
14:30 – 14:50 Drugs, genes and databases for healthy ageing

João Pedro de Magalhães

University of Liverpool, UK
14:50 – 15:10 Coffee pause and networking
4. Stem cell aging
15:10 – 15:30 Muscle stem cell function is impaired during aging

Julia von Maltzahn

Fritz-Lipmann Institute, Germany
5. Short talks
15:30 – 15:45 A research pipeline for the discovery of bioactive small
molecules with healthy ageing-promoting activity from the
marine mesophotic zone

Eleni-Dimitra Papanagnou
University of Athens, Greece
15:45 – 16:00 6-bromo-indirubin-3’-oxime (6BIO), a Glycogen synthase
kinase-3β inhibitor, activates cytoprotective cellular module
and suppresses cellular senescence-mediated biomolecular
damage in human fibroblasts

Aimilia Sklirou
University of Athens, Greece
16:00 – 16:15 Why measuring your aging will help you live longer

Guihem Velve Casquillas

ELVESYS SAS, France
Darwin Microfluidics SAS, France
16:15 – 16:30 Comparative transcriptomics of longevity: methods of
interspecies RNA-seq analysis

Anton Kulaga
Romanian Academy, Romania
6. Natural Products
16:00 – 16:20 AISA can control the inflammatory facet of SASP

Patrizia D'Alessio
University Paris Sud-11, France

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16:20 – 16:40 Frailty in 6XFAD mouse model of Alzheimer’s disease: The
influence of age and proteasome activation

Aleksandra Mladenovic Djordjevic

University of Belgrade, Serbia
7. Inflammaging
16:40 – 17:00 New implications of the inflammasomes in aging and age-
related diseases

Mario D. Cordero
University of Granada, Spain
1. DNA damage and repair (1)
17:00 – 17:20 Systemic DNA damage responses in aging and disease

Björn Schumacher
University of Cologne, Germany
19:00 – 22:00 Informal meeting: Café A La Mort Subite (second floor), rue
Montagne-aux-Herbes Potagères 7

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 FRIDAY NOVEMBER 9th
Day chair: Vincent Fagot
1. Bioinformatics
09:30 – 09:50 Pathways and Terms for Health, Aging, Senescence and
Rejuvenation

Georg Fuellen
University of Rostock, Germany
2. Proteostasis
09:50 – 10:10 Proteasome activation delays aging and progression of age-
related diseases

Efstathios Gonos
National Hellenic Research Foundation, Greece
10:10 – 10:30 A conserved mito-cytoplasmic translational balance links two
longevity pathways

Georges Janssens
University Medical Center Amsterdam, The Netherlands
10:30 – 10:50 Coffee pause and networking
10:50 – 11:10 Nature-Made Catalytic Antibody Platform: From Heisenberg’s
Uncertainty Principle to the Brink of Medical Interventions

Sudhir Paul
University of Texas, USA
Covalent Bioscience Inc, USA
3. Metabolism
11:10 – 11:30 Michael Ristow
ETH Zurich, Switzerland
4. Neurobiology
11:30 – 11:50 The importance of the blood-cerebrospinal fluid barrier in
maintaining optimal brain function in aging and age-related
diseases

Roos Vandenbroucke
University of Ghent, Belgium
5. Short talks
11:50 – 12:00 AgeCurve and age-associated protein patterns

Attila Csordas
AgeCurve, UK
12:10 – 13:30 Lunch
13:30 – 14:30 Andrea Maier
Keynote 2 VU University Amsterdam, The Netherlands
University of Melbourne, Australia

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 6. Rejuvenation strategies
14:30 – 14:50 An overview of recent progress in projects performed or
funded by SENS Research Foundation

Aubrey de Grey
SENS Research Foundation, USA
14:50 – 15:10 Coffee pause and networking
7. DNA damage and repair (2)
15:10 – 15:30 Insilico biomarkers and interventions in aging

Alexey Moskalev
Komi Scientific Centre, Russian Federation
Syktyvkar State University, Russian Federation
15:30 – 15:50 Exploring the phenotypical landscape of aging

Morten Scheibye-Knudsen
University of Copenhagen, Denmark
15:50 – 16:10 Genomic deletion of GIT2 induces a premature age-related
thymic dysfunction and systemic immune system disruption

Stuart Maudsley
University of Antwerp, Belgium
16:10 – 16:30 Preventive medicine: Hope versus hype

Sven Bulterijs
Heales vzw, Belgium
16:30 – 17:30 Can preventive medicine and screening contribute to
Panel session 1 extending healthy lifespan?

Moderator: Sven Bulterijs

Panel members: Kris Verburgh, Jian Fransén, Laurens
Eeckhout
19:00 – 22:00 Informal meeting: Café A La Mort Subite (second floor), rue
Montagne-aux-Herbes Potagères 7

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 SATURDAY NOVEMBER 10th
Day chair: Alex Tietz-Latza
09:30 – 09:50 Accelerating the availability of rejuvenation therapy

Michael Greve
Forever Healthy, Germany
09:50 – 10:10 The Open Longevity Project

Anastasia Egorova
Open Longevity, Russian Federation
Science for Life Extension Foundation, Russian Federation
10:10 – 10:30 Aging fits the disease criteria of the International Classification
of Disease

Daria Khaltourina
International Longevity Alliance
Council for Public Health and Demography, The Russian
Federation
10:30 – 10:50 Coffee pause and networking
10:50 – 11:10 Why are so few people in favour of life extension, and what
can we do to change that?

Nicola Bagalà
LEAF, USA
11:10 – 11:30 How to be more effective in activism for longevity?

Attila Csordas
Cambridge, UK
11:30 – 11:50 Prospects of practically shattering the ceiling of human
longevity

Victor Björk
Heales vzw, Belgium
11:50 – 12:10 Lifespan.io’s outreach experience: How to reach millions
instead of hundeds?

Elena Milova
LEAF, USA
12:10 – 13:30 Lunch
13:30 – 14:00 Investing in longevity
Panel session 2
Moderator: Peter Wicks
Panel members: Alexandra Sharon Bause, Michael Greve,
Elena Milova

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14:00 – 14:20 An European campaign for longevity/amortality/immortality

José Cordeiro
Singularity University, USA
14:20 – 14:40 Coffee pause and networking
14:40 – 15:00 How to organize clinical trials on longevity

Didier Coeurnelle
Heales VZW, Belgium
15:00 – 16:00 How to favor clinical tests on longevity. Legal aspects,
scientific aspects, technical aspects, political aspects.

Moderator: Didier Coeurnelle

Panel members: Guilhem Velve Casquillas, Sebastian
Sethe, Edouard Debonneuil
16:00 – 16:40 General discussion and conclusion of the conference

Moderator: Alexander Tietz

16:40 – 17:00 Closing ceremony / Goodbye speech

Sven Bulterijs
Heales VZW, Belgium

Didier Coeurnelle
Heales VZW, Belgium
17:30 – 19:00 Debriefing and perspectives meeting in the Café A La Mort
Subite (second floor), rue Montagne-aux-Herbes Potagères 7