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What is Rabies?
Rabies is a viral disease that causes acute inflammation of
the brain in humans and other warm-blooded animals.
Wolves
Cattle
Sheep / Goats
Mongoose Pigs
Donkeys
Horses
Dogs
Cats
3 – 5% of
Cause > 90% of the Human Human cases
cases
FACTS ON RABIES
50% of the deaths due to Rabies are among children under
15 years age.
Transmission: Bite
Aerosol
Ingestion
Transplantation
Rabies Transmission
Saliva from bite of infected animal
Scratch
Theoretical risk
• Weeks to months
Furious Rabies
•Serology
• Human diagnosis
– Several tests required for ante-mortem diagnosis
– Saliva, serum, cerebrospinal fluid, hair follicle
from nape of neck
DIFFERENTIAL DIAGNOSIS
Landry/Guillan-barre syndrome
Poliomyelitis
Pre-exposure Prophylaxis
Post-exposure Prophylaxis
Primary Vaccinations
Purified Chick
Pre-exposure or
Embryo Cell Vaccine RabAvert® Intramuscular
Postexposure
(PCEC)
PPT- 22
Rabies— Vaccination
• Previously unvaccinated persons get 4 doses
– Days 0, 3, 7, and 14
– 5th dose dropped from vaccine schedule last year
– Intramuscular injections
Primary Vaccination
PPT-
Booster Doses
Continuous Risk
• People who work with rabies virus in research
laboratories or vaccine production facilities are
at the highest risk for unapparent exposures
• Such persons should have a serum sample
tested for rabies antibody every six months.
• Vaccinated livestock
– Rabies booster vaccine immediately
– 45 day observation
– Multiple rabid animals in a single herd is unusual
• Restriction of entire herd usually not necessary
– Coordinate with WV Dept. of Agriculture
Management of Animals Potentially
Exposed to Rabies
• Unvaccinated livestock
– Euthanasia
– Confined under close observation for 6 months
• Any signs of illness should be reported and animal
euthanized and tested for rabies
– Vaccination during confinement can be done
– Coordinate with WV Dept. of Agriculture