Pregnancy Affectations

- Women with CF may have a higher risk of getting gestational diabetes. Diabetes is
when you have too much sugar in your blood. Too much sugar in your blood can
damage organs in your body, including blood vessels, nerves, eyes and kidneys.
Diabetes must be treated during pregnancy for the health of the mother and the
baby, and after pregnancy for the health of the mother.
- There are two types of tests that can tell you if you have CF or if you’re a carrier.
Both are safe to take during pregnancy. Your partner can have the tests, too.

 A blood test
 A swab of cells inside your mouth. This means your
provider rubs a cotton swab against the inside of your
cheek to get some cells.

If you or your partner has CF or is a CF carrier, you can have a prenatal test to find
out if your baby has the condition or is a carrier.

TESTS:

 Chorionic villus sampling (also called CVS). This test checks

tissue from the placenta for birth defects and genetic
conditions. You can get CVS at 10 to 13 weeks of pregnancy.

 Amniocentesis (also called amnio). This test checks amniotic

fluid from the amniotic sac around your baby for birth defects
and genetic conditions. You can get this test at 15 to 20 weeks
of pregnancy.

Physiological Impact

Cardiac output, blood volume and resting ventilation all increase during pregnancy.
Static lung volumes including total lung capacity and residual volume are reduced
as a result of upward displacement of the diaphragm.. For healthy women, spirometry is
generally preserved throughout pregnancy, although some series have noted reductions
in both forced expiratory volume in 1 s (FEV1) and forced vital capacity as pregnancy
progresses. The extent of change in spirometry during pregnancy in women with CF is
variable. Elevations in pulmonary artery pressure are common in CF and hemodynamic
may be significantly worsened in those with advanced lung disease and severe
pulmonary hypertension. Therefore, patients with severe airflow limitation and/or
markedly impaired gas exchange are at risk of respiratory decompensation as
pregnancy progresses.
Can you pass CF to your children?
Yes. But it depends on both you and your partner. If you and your partner both have CF,
your baby will have CF.

If you and your partner are both CF carriers, there is a:

 3-in-4 chance (75 percent) that your baby won’t have CF

 1-in-2 chance (50 percent) that your child won’t have CF but will be a CF carrier
 1-in-4 chance (25 percent) that your child will have CF
 1-in-4 chance (25 percent) that your child will not have CF and not be a carrier

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4934991/

http://www.pregnancybirthbaby.org.au/cystic-fibrosis

http://www.marchofdimes.org/complications/cystic-fibrosis-and-pregnancy.aspx