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A low power miniaturized monitoring system of six human physiological parameters based on wearable body
sensor network
Congcong Zhou Chunlong Tu Jian Tian Jingjie Feng Yun Gao Xuesong Ye
Article information:
To cite this document:
Congcong Zhou Chunlong Tu Jian Tian Jingjie Feng Yun Gao Xuesong Ye , (2015),"A low power miniaturized monitoring
system of six human physiological parameters based on wearable body sensor network", Sensor Review, Vol. 35 Iss 2 pp. 210 -
218
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http://dx.doi.org/10.1108/SR-08-2014-687
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Abstract
Purpose – The purpose of this paper is to design a low-power human physiological parameters monitoring system which can monitor six vital
parameters simultaneously based on wearable body sensor network.
Design/methodology/approach – This paper presents a low-power multiple physiological parameters monitoring system (MPMS) which comprises
four subsystems. These are: electrocardiogram (ECG)/respiration (RESP) parameters monitoring subsystem with embedded algorithms; blood oxygen
(SpO2)/pulse rate (PR)/body temperature (BT)/blood pressure (BP) parameters monitoring subsystem with embedded algorithms; main control
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subsystem which is in charge of system-level power management, communication and interaction design; and upper computer software subsystem
which manipulates system function and analyzes data.
Findings – Results have successfully demonstrated monitoring human ECG, RESP, PR, SpO2, BP and BT simultaneously using the MPMS device. In
addition, the power reduction technique developed in this work at the physical/hardware level is effective. Reliability of algorithms developed for
monitoring these parameters is assessed by Fluke Prosim8 Vital Signs Simulators (produced by Fluke Corp. USA).
Practical implications – The MPMS device provides long-term health monitoring without interference from normal personal activities, which potentially allows
applications in real-time daily healthcare monitoring, chronic diseases monitoring, elderly monitoring, human emotions recognization and so on.
Originality/value – First, a power reduction technique at the physical/hardware level is designed to realize low power consumption. Second, the
proposed MPMS device enables simultaneously monitoring six key parameters. Third, unlike most monitoring systems in bulk size, the proposed
system is much smaller (118 ⫻ 58 ⫻ 18.5 mm3, 140 g total weight). In addition, a comfortable smart shirt is fabricated to accommodate the portable
device, offering reliable measurements.
Keywords Body sensor network, Healthcare monitoring, Low power, Smart shirt, Wearable
Paper type Research paper
Nomenclature 1. Introduction
Abbreviation Health monitoring systems have drawn more and more
ECG ⫽ Electrocardiogram attention, as people suffering from age-related diseases are
RESP ⫽ Respiration increasing and the aging process is speeding up in many
SpO2 ⫽ Blood oxygen countries. And the cost of hospitalization and patient care
PR ⫽ Pulse rate continuously rises worldwide. Health monitoring system
BT ⫽ Body temperature which works out of hospitals may assist residents and
BP ⫽ Blood pressure caregivers by providing non-invasive or invasive continuous
MPMS ⫽ Multiple physiological parameters monitoring health monitoring with minimum interaction of doctors and
system patients, and thus helps to reduce hospitalization and
BSN ⫽ Body sensor network healthcare costs (Baig and Gholamhosseini, 2013).
RA ⫽ Right arm
Body sensor network (BSN) is widely used in health
LA ⫽ Left arm
monitoring systems due to an easy integration of both sensors
LL ⫽ Left leg
and sensor interconnections. Within the progress in network
RL ⫽ Right leg
communication, wireless systems make it possible to provide
AFE ⫽ Analog front-end
MCU ⫽ Main control unit long-term continuous sensing without activity restriction and
behavior modification.
The current issue and full text archive of this journal is available on
Emerald Insight at: www.emeraldinsight.com/0260-2288.htm
This work is supported by National Key Technology R&D Program in the
12th Five-Year Plan of China (No. 2012BAH06F00) and National
Science and Technology Major Project of the Ministry of Science and
Technology of China (No. 2013ZX03005008).
Sensor Review
35/2 (2015) 210 –218 Received 18 August 2014
© Emerald Group Publishing Limited [ISSN 0260-2288] Revised 24 October 2014
[DOI 10.1108/SR-08-2014-687] Accepted 1 December 2014
210
Low power miniaturized monitoring system Sensor Review
Congcong Zhou et al. Volume 35 · Number 2 · 2015 · 210 –218
Researchers have developed integrated carrier products, control subsystem 3 and smart shirt in detail. In Section 3,
such as smart clothing, pieces of jewelry, wristwatches, rings experiments are conducted to evaluate the performance of the
(Wu et al., 2009), shoes (Bamberg et al., 2008), glasses system. In Section 4, test results are discussed. Finally, this paper
(Coughlin, 2007), gloves (Simone et al., 2007) and so on, to is concluded in Section 5.
allow sensors to be worn as accessories by users. Among the
location of sensing technology systems mentioned above, 2. System design and algorithms
smart clothing has the ability to monitor more vital signs than
Different physiological parameters are classified into
others. The Georgia Tech Smart Shirt characterized as a
subsystems based on the detection principles and system
“wearable motherboard”, allowing a variety of vital parameters to
resources for power consumption management. Distributed
be incorporated into the vest which could be worn by the
and flat design methods are applied here to miniaturize the
soldiers. But, blood pressure (BP) was not considered in their
monitoring system. The multiple physiological parameters
vest (Gopalsamy et al., 1999).
monitoring system (MPMS) device is mainly composed of
A wearable medical monitoring and alert system (AMON)
four subsystems. They are ECG/RESP parameters monitoring
targeting high-risk cardiac/respiratory patients was developed
subsystem 1 with embedded algorithms; SpO2/PR/BT/BP
under grants from the European Union FP5 IST program.
parameters monitoring subsystem 2 with embedded algorithms;
The wearable monitor consisted of a wrist-worn device which
main control subsystem 3 which is in charge of system-level
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Figure 2 The block diagram of ECG/RESP monitoring subsystem 1 determined by following equation (1), whereindicates the
first-order differential signal of peak position n:
Peaknumbers
Respiration_rate ⫽ 600 ⫻ (2)
Peakposition
circuit. Then, data are fed to MCU1 via SPI at the baud rate filter with a cutoff frequency of 100 Hz and a high-pass filter
of 500,000 Hz and transmitted through UART1 at the baud with the corner frequency of 0.5 Hz to filter unnecessary signal
rate of 115,200 to the main MCU3 of main control subsystem components. Second, a five point’s average algorithm is
3. An RC filter acts as an electromagnetic interference filter applied to smooth ECG signals and attenuate 50 Hz noise in
with the ⫺3dB bandwidth of 1 MHz at the input is applied. real time. After that, ECG signals are stored in data arrays and
Also, a RL drive circuit is designed to reduce interference sent to upper compute every second.
generated by surrounding electromagnetic devices. The detection of the QRS complex is important in ECG
Impedance pneumography technique to measure respiration monitoring. But it is difficult because it has a time-varying
rate is realized here. RA and LA leads which work as both drive morphology and is subject to physiological variations due to
the patients. In our work, a QRS detection algorithm based on
electrodes and receive electrodes for RESP monitoring are
wavelet transform is designed in the upper computer. The
multiplexed with ECG monitoring. The high-frequency AC
mother wavelet which possesses appropriate high vanishing
current source (32 kHz, square wave) which works as a modulate
rules used to detect the signal singularity is Mexican Hat
signal is generated by the MCU1. Then, signals obtained are
(Mexh) wavelet. The Mexh wavelet is a second-order
amplified by INA321 (Texas Instruments), which provides
derivative Gaussian function whose shape is like a Mexican
low-noise amplification of differential signals with 40 A current.
hat, as described by Lee et al. (1998). The time domain and
The analog front end has a basic gain of 15 and a high common
frequency domain characters are shown in Figure 3(a). The
mode rejection radio of ⫺94 dB. After the signals are amplified, standard Mexh wavelet and its Fourier transform can be
an infinite gain multiple feedback (MFB) band-pass filter circuit expressed as follows:
is designed with the central frequency at 32 kHz and passband
bandwidth of 6.5 kHz, then it is followed by a detection circuit to 2
t
here is OPA348 (Texas Instruments) with supply current of 45 () ⫽ 兹2 ⫻ a ⫻ 2 ⫻ e 2 (4)
A. The demodulated and filtered outputs are then digitized by
analog-to-digital converter (ADC) of MCU1. At last, respiration where:
waves are sent to the main MCU3 of main control subsystem 3
at the baud rate of 115,200. 2 1
a⫽ 4.
2.1.1 RESP algorithm 兹3
The respiration waves are converted by ADC from analog to
The main steps of QRS detection are as follows:
digital, then respiration rate is computed by the following ● Step 1: Preprocess ECG signals with low-pass digital
algorithm.
Butterworth filter, high-pass filter and average algorithm
The RESP algorithm is applied to the data buffer of 20 described above. After ECG signals are stored in data
seconds. First, the signals pass through a low-pass digital arrays and sent to upper compute, the data are
Butterworth filter with a cutoff frequency of 1.5 Hz to filter standardized by using discrete wavelet transform.
high-frequency signal components. Second, the data are ● Step 2: Calculate the positive maximum detection signals
sorted every 1 second and the respiration rate is calculated (Pmax) and the minimum detection signals (Pmin),
every 5 seconds. Third, the peak positions of signals are determine the threshold of R(ThR) wave by:
detected with the indirect derivative calculation method along
冉兺 冊
with peak numbers. The sample rate here is 10 Hz, which n m
means 200 data during the detection period of 20 seconds.
The values and peak positions of respiration signals are
ThR ⫽ b ⫻
1
1
P ⫺
n max 兺 m1 P
1
min (5)
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Congcong Zhou et al. Volume 35 · Number 2 · 2015 · 210 –218
● Step 3: Set an absolute un-detection during time which can temperature from 32°C to 42°C by placing the sensor in one
be set as 200 to 400 ms according to the physiological arm of the bridge circuit. The CCS circuit which outputs
characteristics of different situations. constant current of 400 A consists of LM334M and
● Step 4: Detect the QRS feature points, such as Q wave and 1N4148. The temperature sensor used here is Platinum
S wave. Thermistor (PT100) which has a resolution of 0.1 per cent.
Figure 3(b) depicts the results of QRS complex detection. In The results of temperature are digitized by ADC of MCU2
our future work, real-time QRS detection algorithm used for a and then sent to the main MCU3 after algorithm.
low-power embedded system will be studied. The SpO2/PR monitoring block in subsystem 2 is based
on Langbert – Bill laws. Red light with 660 nm central
2.2 Design of SpO2/PR/BT/BP parameters monitoring wavelength and near-infrared light with 940 nm central
subsystem 2 wavelength irradiate finger tips alternately. SpO2 is calculated by
Figure 4 depicts the block diagram of SpO2/PR/BT/BP measuring periodical changes of the two types of light, while PR
monitoring subsystem 2. The temperature monitoring block is calculated at the same time. The results are fed to MCU2 via
in subsystem 2 consists of a calibration circuit, a constant UART0 and then sent to the main MCU3.
current source (CCS) circuit and a high-precision gain Non-invasive BP measurement method is applied here. The
amplifier INA321 with the gain of 15. The calibration circuit BP monitoring block in subsystem 2 consists of two functional
consists of a bridge circuit which is calibrated to read parts, one is detection circuits and the other is protection
circuits. The BP detection circuits consist of preamplifier with
the gain of 15, MCU3, band pass filter circuits with the
Figure 4 The block diagram of SpO2/PR/BT/BP monitoring bandwidth of 0.1-30 Hz and control circuits of pump. The
subsystem 2
protection circuits consist of a comparator and control circuits
of valves, these circuits will automatically work as soon as the
pressure detected is above the threshold (260 mmHg). The
detected signals are digitized by ADC of MCU2 and then sent
to the main MCU3 after algorithms.
2.2.1 BP algorithm
After the BP waves digitized by ADC of MCU2, the peak
numbers and peak positions are recorded in two data arrays,
respectively.
The measurement of BP in this thesis is based on the
oscillometric method. First, detect the peak points of BP
waveform, according to which the best Gaussian fitting curve
which fits the contour line of the waveform is matched. Restrict
to the limitation of MCU2 resources, the peak points used to
calculate the fitting curve are limited. Second, calculate the
locations of diastolic blood pressure (DBP) and systolic blood
pressure (SBP) by the proposed coefficients which are statistics
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Congcong Zhou et al. Volume 35 · Number 2 · 2015 · 210 –218
results from massive experiments based on the prototypes of the and cotton. Figure 6 illustrates the integration sites of sensors
MPMS device. At last, DBP, SBP and mean BPs are calculated. and electrodes in the shirt.
There is evidence indeed that emotional states have their
2.3 Design of main control subsystem 3 corresponding specific physiological parameters that can be
The main control subsystem 3 mainly consists of battery mapped, respectively (Lisetti and Nasoz, 2004); our MPMS
management circuits, peripherals such as keyboards and LCD device with smart shirt provides another option to real-time
screen, main MCU3 (MSP430FG5438) with four monitor six vital physiological parameters for emotions
communication modules, power management module and computing without interfering with the normal activities of a
wireless module, as depicted in Figure 5. person, which makes it more reliable.
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Congcong Zhou et al. Volume 35 · Number 2 · 2015 · 210 –218
Figure 7 Prototype of the developed MPMS device with wireless 2012). An energy-efficient MAC protocol which was designed
module integrated specifically for a star topology composed of clusters was also
presented (Omeni et al., 2008). Nabi et al. (2010) proposed a
multi-hop protocol for human body health monitoring. Li and
Tan (2010) proposed a novel time division multiple access-based
MAC protocol designed for BSNs. These studies all focused on
MAC layer to reduce power consumption during wireless
transmission.
Some other works did not describe how to realize low power
consumption. Li (2010) presented a wireless sensor network
system whose main board was a low-power consumption main
board with the “H8” micro controllers, and extended to be
available for external usages.
A power reduction technique at the physical/hardware level
compared to existing research works is designed. Different
physiological parameters are classified into subsystems based
Figure 8 Remote monitoring station and MPMS device with smart on the detection principles and system resources. In system
shirt
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wireless data communications, the power consumption (active collection accuracy of standard ECG signals was above 99 per
mode) of ECG module was 67 mW, and Bluetooth module cent, which showed that the ECG monitoring block could
was 89.1 mW. Compared to present research, our power monitor the ECG parameter reasonably.
reduction technique at the physical/hardware level and The accuracy of respiration rate measurements was ⫾1
efficient operating procedure developed here were effective. times per minute at the range of 15 to 40 times per minute, as
shown in Figure 11.
4.2 Results of ECG/RESP parameters test
The MPMS device was tested for safety issues according to
Medical electrical equipment-Part 1: General requirements 4.3 Results of SpO2/PR/BT/BP parameters test
for safety (GB 9706.1-2007/IEC 60601-1) standards; the The systolic pressure range tested was from 80 to 160 mmHg
patient leakage current, auxiliary leakage current and and diastolic pressure range was from 50 to 120 mmHg. BP
enclosure leakage current measured were all below 1 A, test results at the PR of 80 bpm and pulse volume of 1 mL are
while maximum permitted was 10 A for each. shown in Table II. The dynamic error of both systolic pressure
The proposed MPMS device was estimated by Fluke Prosim8 and diastolic pressure was below 8 mmHg.
Vital Signs Simulators (produced by Fluke Corp. USA). Setting Fluke Platinum Resistance thermometer was used to
the ECG and RESP parameters of ProSim8 and connecting the calibrate the BT module. The measurement accuracy of BT
MPMS device to the lead sites as shown in Figure 9, the were: ⫾0.3°C at the range of 32-35.2°C and 41.1-42.0°C,
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measured ECG/RESP parameter waves are shown in Figure 10. ⫾0.2°C at the range of 35.3-36.9°C and 39.1-41.0°C and ⫾
There were obvious T waves, P waves and QRS complex waves 0.1°C at the range of 37.0-39.0°C, as shown in Figure 12.
in ECG curves, as shown in Figure 10, in I, III, aVR leads, the
Figure 9 Experiment platform of ECG/RESP parameters test Figure 11 Experiment results of RESP rate
Figure 10 The real-time standard ECG/RESP parameter waves displayed on the upper computer
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Table II Dynamic blood pressure test results (systolic pressure/diastolic physiological parameters, and reliable results were estimated
pressure mmHg) by Fluke Prosim8 Vital Signs Simulators (produced by Fluke
Corp. USA). The MPMS device is a smart monitoring device
Fluke Prosim8 160/120 140/100 135/95 130/90 126/80
which provides real-time feedback to remote monitoring
MPMS device 158/126 136/104 137/98 130/93 122/76
station and can be operated both by remote terminals and
Fluke Prosim8 117/75 110/70 100/65 90/60 80/50
local keyboards. The smart shirt proposed here is comfortable
MPMS device 118/75 111/75 100/65 90/61 79/55
to wear and convenient to use. Although progresses have been
made in some way, there are still problems that need to be
solved. In future, as the source is limited in embedded system,
Figure 12 Body temperature test results
higher-level medical algorithms will be implemented to
classify the results in real time. Current results have
demonstrated the feasibility of the solutions to the
technological and scientific issues. Although there are many
studies that focus on health monitoring systems, to the best of
our knowledge, we cannot find a low-power system which
monitors these six physiology parameters at the same time and
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