TUTORIAL 3 BIO 310

MARCH 2013

1. Explain the gametogenesis in

a) male (5 marks)

b) female (5 marks)

2. Define the following terms:

a) phenotype (1 mark)

b) dominant allele (1 mark)

3. Hemophilia is an X-linked recessive gene. Two normal parents produce a child suffering from
hemophilia.

a) Draw a Punnett square representing the cross between the parents. (5 marks)

b) If a father and a son are both suffering from hemophilia and the mother is normal, is it likely that the
son inherited the hemophilia gene from his father? Explain your answer. (3 marks)

SEPTEMBER 2013

1. Describe the spermatogenesis process. (10 marks)

2. Explain an example of codominance in human. (4 marks)

3. Define the following terms:

a) phenotype (2 marks)

b) genotype (2 marks)

c) non-disjunction (2 marks)

4.

a) Define sex-linked inheritance. (2 marks)

b) Based on situations given below, answer the following questions:

John has Jacob’s syndrome.

He is also suffering hemophilia.

His father is normal for both traits.

His mother is a carrier for hemophilia.

i) Predict the genotype of John. (1 mark)

ii) Determine the probability of John’s brother who will suffer from hemophilia. (2 marks)

c) A color blind female marries a normal male.

i) Construct a Punnett square for the above couple. (3 marks)

ii) Determine the probability for the above couple to have a color blind son. (1mark)

iii) Determine the probability for the above couple to have a color blind daughter. (1 mark)

MARCH 2014

1. Explain the processes involved in semen production from the starting of sperm formation to
ejaculation. (10 marks)

2. a) Differentiate between dominant and recessive allele.(6 marks)

b) Determine and explain the genotypes of these three persons. Normal man marries an albino woman
and their first child is an albino. (4 marks)

3. A man with blood type B marries a woman with blood type A. both of them have one of their own
parents with blood type O.

a) Analyse the above situation,

i) state the genotype of the man. (1 mark)

ii) state thegenotype of the woman.(1 mark)

b) Determine whether it is possible for this couple to have child with

i) blood type AB. (1 mark)

ii) blood type O. (1mark)

c) Show your answers in b(i) and b (ii) by using Punnett square. (4 marks)

d) From your Punnett square, calculate the probability for this couple to have a child with

i) blood type A (1 mark)

ii) blood type B (1 mark)

SEPTEMBER 2014

1. Describe the pathway of sperm from the production point in the testes to its ejaculation point at the
penis. Mention all glands that are involved in this process. (10 marks)
2. a)Differentiate between incomplete dominance and codominance. (4 marks)

b) A man and a woman each carry the allele for phenylketonuria (autosomal recessive disorder);
an inborn error of metabolism, while neither of them has this disease themselves.

i) Construct a Punnett square for the above couple.(4 marks)

ii) Determine the probability for their child to have the disease. (1 mark)
iii) If the couple has a normal child, without phenylketonuria, predict the probability that this
child is a carrier of the disease. (1 mark)
3. a) Explain the non-disjunction of autosomal chromosomes that lead to Down syndrome. (3
marks)
b) Both mother and father of a male hemophilia appear to be normal.

i) Predict from whom he inherits the allele for hemophilia. (1 mark)

ii) Determine the genotypes of his mother, father and himself. (3marks)
c) A woman is colour blind.
i) Predict the chances that her sons will be colour blind. (1 mark)
ii) If she is married to a man with normal vision, predict the chances that her daughters will be
colour blind and the probability of them becoming carrier.(2 marks)

MARCH 2015
1. Describe the ovarian cycle in human. (10 marks)
2. a) Define phenotype, genotype, dominant trait, recessive trait and test cross respectively. (5
marks)
b) Explain and give one example of polygenic inheritance in human. (5 marks)
3.
a) Earlobe is controlled by complete dominant-recessive inheritance. The phenomenon of having
unattached earlobes is a dominant trait whereas having attached earlobes is a recessive trait. A
woman who has attached earlobes marries a man having unattached earlobes with heterozygous
alleles. Analyze the above situation, by using Punnett square, show the genotypic ratio and
phenotypic of their children. (5 marks)
b) Colour blindness is an X-linked recessive disorder. John has colour blindness, but his sister,
Mary has normal colour vision. John’s mother has normal colour vision whereas John’s father
has colour blindness. Analyze the above situation, by using Punnett square, show the genotypes
of these four persons and indicate from which of the parent that John received the colour
blindness allele. (5 marks)

SEPTEMBER 2015
1. Illustrate with a chart and describe the process of spermatogenesis. (10 marks)
2. Differentiate between phenotype, genotype, alleles, F1 generation and F2 generation.
(5 marks)
3.
a. Mr. Abu has no history of albinism in his family. He marries an albino woman and they have
four children. Construct a Punnett square to show the phenotype and genotype of their children.
(5 marks)

b. A child has blood type O. If the father has blood type A and mother has blood type B, predict
the genotypes of the parents and the possible genotypes of the other offsprings by using a
Punnett square. (5 marks)