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Medico Research Chronicles


“Nanobiotechnology in modern medicine”

ISSN No. 2394-3971

Original Research Article


NANOBIOTECHNOLOGY IN MODERN MEDICINE

Peredkov K.Ya.

National Medical University,


Ukraine, Kyiv

Submitted on: December 2018


Accepted on: December 2018
Email:

Nanomedicine-trend in modern technology, which consists of a combination


medicine, based on the use of the unique of theoretical study and practical research
capabilities of nanomaterials and nano- methods, analysis and synthesis, as well as
objects for the selection, design, and methods of production and application
changes in biological systems on the human products with a given atomic structure by
low-molecular level. controlled manipulation of individual atoms
Nanotechnology- an interdisciplinary and molecules.
field of fundamental and applied science and

Medico Research Chronicles, 2018

Cooperation of biocomposite with bone-оsteointegration, dense fitting closely of bone.

Artificial bone (biocomposites), metals and nonmetals), similar in


bioactive inorganic multiphase composite composition to natural bone mineral and
material (synthesized on the basis of intended to restore it with different
nanocrystals gidroksilappatit, tricalcium- pathologies.
phosphate, bioactive glass, mixed oxides of

Peredkov K. Ya., Med. Res. Chron., 2018, 5 (6), 539-543 539


DOI No. 10.26838/MEDRECH.2018.5.6.472
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Medico Research Chronicles
“Nanobiotechnology in modern medicine”

Possible forms of bioceramics.


The system of artificial bone is multifunctional materials, as they have the ability to
osseointegration, osteoconduction, osteoinduction, osteostimulation, and osteogenesis.

In the complement of biocomposite to be a possibility to add antiseptic preparations.

After the occurrence of the bone- The mechanism, the nature, and rate
ceramic complex in the body, the material is of resorption is planned and managed Medico Research Chronicles, 2018
partially or completely resorbed at the composition and structure of complex
planned time-from 1,5-2 months- to several artificial bone.
years, being replaced by bone tissue, which
consists of products of resorption and
synthesis.

Osteointegration plates in a bone with bioceramics сovering and without.

Peredkov K. Ya., Med. Res. Chron., 2018, 5 (6), 539-543 540


DOI No. 10.26838/MEDRECH.2018.5.6.472
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Medico Research Chronicles
“Nanobiotechnology in modern medicine”

Selection of nonresolution of the immune reactions, and inorganic


complex, which firmly holds the specified bactericidal supplements, obstruction
shape and volume, such as alveolar jaw. inflammatory complications. Due to the
Biocomposite contains only the absence of organic components is possible
highest biocompatibility of inorganic multi sterilization of reusable material.
constituents, which do not cause abnormal

Experimental application of bioceramics in the defects of different bones.

The using of autologous bone-may be biological properties. Using biocomposites


Medico Research Chronicles, 2018

replaced and supplemented by using modern in oral and maxillofacial surgery is possible:
bioactive ceramics with the planned -For replacement elements maxillo-facial
bones and joints.

Peredkov K. Ya., Med. Res. Chron., 2018, 5 (6), 539-543 541


DOI No. 10.26838/MEDRECH.2018.5.6.472
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Medico Research Chronicles
“Nanobiotechnology in modern medicine”

-To fill the bone cavities after capsulotomy - For bone grafting in plastic surgery.
and cystectomy, treatment of osteomyelitis. -To fill bone defects.
-To form the bone wall with perforated
sinusitis.
Medico Research Chronicles, 2018

-For a sinus-lift.
-Аt chronic sinusitis

Peredkov K. Ya., Med. Res. Chron., 2018, 5 (6), 539-543 542


DOI No. 10.26838/MEDRECH.2018.5.6.472
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Medico Research Chronicles
“Nanobiotechnology in modern medicine”

In stomatology: diseases of the maxillofacial area /


-For the filling of periodontal defects. Rybachuk A.V., Rieznichenko L.S.,
-To fill the holes removed teeth. Dybkova S.N. // Ukrainian Scientific
-When you atrophy of alveolar bone in the Medical Youth Journal. Special edition.
jaw bone for augmentation. – 2014. – P. 42-47.
-For obturating dentinal canals. 4. Rybachuk A.V. Silver nanoparticles and
-In a deep root canal fillings, including extra their combination with gold
pix therapy. nanoparticles as new effective
Thus, modern biocomposites antimicrobial substances for
represent the latest concept in the maxillofacial surgery and dental
development of bioactive inorganic implantology / Rybachuk A.V.,
materials for reconstruction of bone tissue. Rieznichenko L.S., Malanchuk V.A. et
References al. // E-MRS Spring Meeting 11-15 May
1.Drexler K.E.Unbundling the future: The 2015, Lille, France. – 2015.
nanotechnology revolution. New York: 5. Rieznichenko L.S. Silver nanoparticles: Medico Research Chronicles, 2018
William Morrow // Quill Books.- 1991.- synthesis, effectiveness in the treatment
225 of purulent inflammatory diseases of the
2. Roco M.C International strategy for maxillofacial area, development of
nanotechnology research and dosage forms / Rieznichenko L.S.,
development // J. Nanoparticle Res.- Rybachuk A.V., Bilous S. B. et al. //
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