Professional Documents
Culture Documents
Pre-requisites
BIOC 212, ANAT 262; one of PHGY 201, PHGY 209 or BIOL 205; one of BIOC 312 or ANAT 365; and BIOC 311 or permission of
instructors. RESTRICTIONS: Students with credit for BIOC 458 may not take ANAT 458, and vice versa.
Course Description
The course presents an integrated treatment of the properties of biological membranes and of intracellular signaling, including
the major role that membranes play in transducing and integrating cellular regulatory signals. Biological membrane
organization and dynamics: membrane transport; membrane receptors and their associated effectors; mechanisms of
regulation of cell growth, morphology, differentiation and death.
Recommended Textbook
There is no assigned text for this course; readings will be posted on myCourses.
© Instructor generated course materials (e.g., handouts, notes, summaries, exam questions, etc.) are protected by law and may NOT be copied or
distributed in any form or in any medium without explicit permission of the instructor. Note that infringements of copyright can be subject to follow up
by the University under the Code of Student Conduct and Disciplinary Procedures.
Evaluation Method
10 % In-class problem solving (lectures #1-15)
30 % Midterm exam (covers material up to and including lectures #1-15, 19)
20 % Oral (or video) presentation
40 % Final exam (covers lectures #16-39 inclusive)
Please Note: Calculators are permitted in examinations as long as they are not programmable and do not have
alphanumeric memory.
Medical Notes
Students unable to attend the midterm exam for medical reasons must bring a valid medical note within 1 week of the
scheduled midterm to: Undergraduate Affairs Administrator
McIntyre Medical Building Room 905A
undergrad.biochem@mcgill.ca
A make-up deferred midterm will be scheduled after the 2 weeks. If a legitimate doctor’s note is not provided, you will
receive a zero on the midterm.
Grading:
The department will NOT revise/upgrade marks except on sound academic grounds. Once computed, the marks in this
course will NOT be altered/increased. Decimal points will be “rounded of” as follows: if the final aggregate mark is
computed to be 79.5%, the mark will be reported as 80% (an A-); a final aggregate mark of 79.4% will be reported as 79%
(a B+). These marks are FINAL and NON-NEGOTIABLE.
Oral presentations
1. In teams of 3-4 students (team size varies upon enrollment), choose a topic among:
M. Denis Aquaporin 1-2, Nav vs Kv channels, Glut 4, Caveolin1, CFTR, ABCA1, SREBP/SCAP, LDLR, Dynamin,
CD-36, Perilipin-1, Hepatitis C, Hyaluronidase-2, Glutamate receptor, A, LeuT, SERT
N. Lamarche-Vane Insulin receptor, EGFR, RhoA, p190RhoGAP, DOCK180, GSK-3, ERK1/2, Smad4, TGFDLL4, WASP
D. Reinhardt Cannabinoid receptor, μ-opioid receptors, Integrin β1, Integrin β4, laminin 332, collagen VII, Focal
adhesion kinase, dystroglycan, DDR receptor, CD44.
C. Autexier phospholipase C (PLC)-gamma 1, atypical protein kinase C (PKC) zeta and/or iota, Class III
PI3K Vps34p, SH2 domain-containing inositol phosphatase(SHIP) 1 and/or 2, scaffold protein
Par6
Useful resources
Student Rights and Responsibilities
https://www.mcgill.ca/students/srr/academicrights
McGill University values academic integrity. Therefore, all students must understand the meaning and consequences of cheating , plagiarism and
other academic offences under the Code of Student Conduct and Disciplinary Procedures (see http://www.mcgill.ca/students/srr/honest/ for
more information).
Time management
https://www.mcgill.ca/osd/student-resources/learningresources/time-management
Stress management
https://www.mcgill.ca/osd/student-resources/learningresources/stress-management