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ADJUSTMENT PROBLEMS OF WOMEN IN

CITY LIFE

Miss Bakhtawar Muneer

Miss Aysha Anum

xxxx/KMU/IBMS/MPhil/xx/x

xxxx/KMU/IBMS/MPhil/xx/x

MA Thesis

Institute of Social Sciences

University of Peshawar
25th October, 2018
ADJUSTMENT PROBLEMS OF WOMEN IN
CITY LIFE

A thesis submitted in the partial fulfillment of the requirement for the


degree of

Master of Arts in Social Work

Miss Bakhtawar Muneer

Miss Aysha Anum

xxxx/KMU/IBMS/MPhil/xx/x

xxxx/KMU/IBMS/MPhil/xx/x

MA Thesis
Institute of Social Sciences

University of Peshawar

25th October, 2018


CERTIFICATE
This thesis by Dr. xxxxxxxx is accepted in its present form, by the Department of
Anatomy, Institute of Basic Medical Sciences, Khyber Medical University Peshawar,
as satisfying thesis requirements for award of degree of Master of Philosophy in
Anatomy.

Supervisor: ____________________

(Dr. xxxxxxx)

Internal Examiner: ____________________

(Dr. xxxxx)

External Examiner: ____________________

(Dr. xxxxxxxx)

Director: ____________________

(Drxxxxxxx)

Date: Jxxxx 30, 2018

i
DEDICATION
I dedicate my work to my support system,
xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx

ii
DECLARATION
I, Dr. xxxxxxx, hereby affirm solemnly that the whole research process and its output
presented in this thesis draft is my own accomplishment carried out in the IBMS KMU
(Institute of Basic Medical Sciences, Khyber Medical University), Peshawar. I have
myself compiled and scribed this thesis draft.

This material is an original work and has never been previously presented for any
degree awarding examination. Also, nothing has been just copied and used from any
other available resources hence abiding by the international copyright law.

I also affirm that I have a complete understanding of the terms ‘copyright’ and
‘plagiarism’. I take complete accountability of the consequences for any desecration of
the rules and guidelines of research writing in case they are caught in my thesis.
Software ‘Turnitin’ was used to check the thesis for plagiarism.

Name: Dr. xxxxxxxxx

Signature: _____________

xxxxxxxxx, 2018

iii
ACKNOWLEDGMENT
Before all else, I truly thank Allah Subhanahu wa ta'ala for everything so far, especially
for enabling me to achieve the goal of completing this research work.

The completion of my MPhil program is largely because of my supervisor,


xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.

I am also grateful to
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xxxxxxxxxxxxxxxxxxx

Not forgetting my team, xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx as preparing study


chemicals.

Special thanks to xxxxxxxxxxxxxxxxxxxxxxxx Statistics Department and


xxxxxxxxxxxxxxxxxxx Peshawar University for helping me through thesis results.

I also express gratitude to


xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
xxxxxxxxxxxxxxxxxxxxxxxxxxx help at different stages.

I also owe gratefulness to my husband,


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xxxxxxxxxxxxxxxxxxxxxxx Jawad Tariq for proof reading it.

Finally, a lasting tribute


xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
xxxxxxxxxxxxxxxx.

Dr. xxxxxxxxxxxxxxxxxx

iv
ABSTRACT
Background
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Methods
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Results
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Conclusion
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v
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Keywords
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vi
TABLE OF CONTENTS

1
1 LITERATURE REVIEW 11

1.1 Preface 11

1.2 yyyyyy 11

1.2.1 nnnnnnnnnnn 11

1.2.2 cccccccccccccccccccc 13

1.2.3 eeeeeeeeeeeee 13

1.2.4 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx 13

1.2.5 cccccccccccccccccccccccccccccccccccccc 14

1.2.6 ppppppppppppppppppp 16

1.3 ddddd 16

1.3.1 ccccccccccccccccccccccccccccc 16

1.3.2 Mxxxxxxxxxxxxxx 16

1.4 Scope of Study 19

1.5 Objectives 20

2 MATERIAL AND METHODS 21

2.1 Study Approval and Setting 21

2.1 Study Sample 21

2.2 Study Chemicals – Details and Doses 22

2.3 Research Study Design 26

2.4 Research Study Period 28

2.4.1 Specimen Collection and Fixation 28

2.5 Processing 29

2.5.1 Tissue Samples Arrangement and Grouping 29

vii
2.5.2 Tissue Processing – Setting 29

2.5.3 vvvvvvvvvvvvvvvvvvvvvvv: 30

2.6 Lggggggggggggggggggggggg 30

2.6.1 hhhhhhhhhhhhhhhhhhhhhhhhhhhhhhh 30

2.7 Statistical Analysis of Data 34

2.7.1 Hypothesis based results methodology 34

2.7.2 Statistical tests 36

3 RESULTS 38

3.1 Results as per Study Objectives 38

3.2 Study Parameters (Dependent Variables) for Results: 38

3.2.1 General Observations 38

3.3 ddddddddddddddddddddd 41

3.3.1 Objective based results for hypothesis testing 42

4 DISCUSSION 43

4.1 Overview 43

4.2 gggggggggggggggggggggggggggggg 43

4.3 Objective 1: dddddddddddddddddddddddddddddddddddd 44

4.4 Objective 2: 44

4.5 Objective 3: dnnnnnnnnnnnnnnnnnnnnnnnnnnnnn 44

4.6 Limitations 44

5 CONCLUSION 46

6 REFERENCES 47

APPENDICES 71

viii
LIST OF TABLES
Table 1-1: Chemical Classification of Pesticides2,3,6–8 12

Table 2-1: Details of the study chemicals administered to treatment groups 23

Table 2-2: Details of laboratory chemicals used in the study procedures 23

Table 2-3: ffffffffffffffffffffffffs29,30 26

ix
LIST OF ABBREVIATIONS
IBMS Institute of Basic Medical Sciences

KMU Khyber Medical University

b.w. Body weight

DLM Deltamethrin

WHO World Health Organization

UNCETDG United Nations Committee of Experts on the Transport of


Dangerous Goods

GHS Globally Harmonized System

FAO/WHO Food and Agriculture Organization/World Health Organization

JMPR Joint Meeting on Pesticide Residues

MRL Maximum Residual Level

LD50 Lethal Dose

ADI Acute Daily Intake

RfD Reference Dose

GAP Good Agriculture Practice

STP Societies of Toxicologic Pathology

INHAND International Harmonization of Nomenclature and Diagnostic

Criteria for Lesions in Rats and Mice

IUPAC International Union of Pure and Applied Chemistry

FDA Food and Drug Administration

DMSO Dimethylsulphoxide

x
1 LITERATURE REVIEW

1.1 Preface

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1.2 yyyyyy
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xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
xxxxxxxxxxxxxxxxxxxxxxxxxxxxx 2–5

1.2.1 nnnnnnnnnnn

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11
LITERATURE REVIEW

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xxxxxxxxxxxxxxxxxxxxxxxxxxxxx.1,2

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Table 1-1: Chemical Classification of Pesticides2,3,6–8

No. CHEMICAL FAMILY EXAMPLES

1 Pyrethroid (Botanical)8 Bioallethrin, Deltamethrin, Cypermethrin, Rotenone, Pyrethrins

2 Carbamates Aldicarb, Bendiocarb, Carbaryl, Carbofuran

3 Organophosphate Chlorpyrifos, Parathion, Diazinon, Dichlorvos (DDVP)

4 Organochlorine Dichlorodiphenyltrichloroethane (DDT), Dieldrin

5 Carbamates fungicides Maneb, Mancozeb, Butylate, EPTC

6 Dichlorophenylethanes Cyclodienes, Chlordane, Chlorobenzilate

7 Triazines and Triazoles Amitrole, Atrazine, Cyanazine, Propazine

8 Benzoic acid and Phenoxy 2,4-D, 2,4-DB, DCPA

12
LITERATURE REVIEW

9 Urea compounds Diflubenzuron, Diuron

10 Inorganic compounds Sulfur, Copper, Arsenic, Lead

11 Others Paraquat, Captan

1.2.2 cccccccccccccccccccc

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xxxxxxxxxxxxxxxxxxxxxxxxxxxx.6 as follows6,7:

 ddddddddddddddddddddddddddd

dddddddddddddddddddddddddddddddd been shown in the Table 1-1.2,3,6–8

1.2.3 eeeeeeeeeeeee

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xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.9

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xxxxxxxxxx (Figure 1-1).3,4
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1.2.4 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx

xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxFigure 1-2.2–4
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xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.1,2

13
LITERATURE REVIEW

xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.9

1.2.5 cccccccccccccccccccccccccccccccccccccc

ccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccc
ccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccc
ccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccc
cccccccc.6
ccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccc
cccccccccccccccccccccccccccccccccccccccccccccccccccc.3
ccccccccccccccccccccccccccccccccccccccc
vvvvvvvvvvvvvvvvvvvvvvvvvvvvvvvvvvvvvvvvvvvvvvvvvvvvvvvvvvvvvvvvv.1,9

Chlorinated
Carbamates[4
hydrocarbons
%
9%
Pyrethroids
47%

Organophospha
tes[40%

Common Pesticides

Figure 1-1: Percentages of common registered pesticides

14
LITERATURE REVIEW

Figure 1-2: Pesticide percentage usage depending upon the target population2–4

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xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
xxxxxxxxxxx.10,11

15
LITERATURE REVIEW

1.2.6 ppppppppppppppppppp

oooooooooooooo
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1.3 ddddd

1.3.1 ccccccccccccccccccccccccccccc

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xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.41

.44

1.3.2 Mxxxxxxxxxxxxxx

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xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.45–49

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16
LITERATURE REVIEW

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xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.53

Gross aaaaaaaaaaa

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xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.43,54–56,57

ssssssssssssssssssssssssssssssssssssss:

 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
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xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxsssssssssssssssssssssss
sss.52,54

17
LITERATURE REVIEW

Figure 1-4: Porta hepatis cross-section showing


Figure 1-3: Rat liver in situ during dissection
the structures of portal triad of the liver
(With due acknowlegment, taken from:
(Reproduced with acknowledgement from “Gray’s
http://www.auckland.ac.nz/theinsideword/wp-
anatomy: the anatomical basis of clinical practice54)
content/uploads/2013/07/rat-upper.jpg63)

18
LITERATURE REVIEW

1.4 Scope of Study


sssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssbbbbbbbbbbbbbbbbbbb
bbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbb
bbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbb
bbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbb
bbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbb
bbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbb
bbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbb
bbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbbb.

n plus curcumin simultaneously and curcumin following deltamethrin on rat liver.

19
LITERATURE REVIEW

This aim was achieved by:

1. ssssssssssssssssssssssssssssssssssssssssssssss.

2. ssssssssssssssssssssssssssssssssssss.

3. sssssssssssssssssssssssssssssssssssssssssssssssssssss.

1.5 Objectives

The objectives of this study were:

1. ggggggggggggggggggggggggggggggggggggggggggggggggggggggggggggggg
gggggggggggggggggggggggg

2. ggggggggggggggggggggggggggggggggggggggggggggggggggggggggggggggg
ggggggggggggggggggggggggggggg.

3. .

20
2 MATERIAL AND METHODS

2.1 Study Approval and Setting

After review and approval by Graduate Study Committee (GSC), this research proposal
was approved by the Advanced Study and Research Board (ASRB) under: DIR/KMU-
AS&RB/HE/xxxxxxxxxxx, and Ethical Board under: DIR/KMU-
EB/HE/xxxxxxxxxxxxx. The study was carried out in the Institute of Basic Medical
Sciences (IBMS) of Khyber Medical University (KMU) Peshawar, Pakistan.
xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
xxxxxxxxxThe xxx.46–49,134–136

2.1 Study Sample

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xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.58,137

Figure 2-1: dddddddddddddddddddddddIBMS KMU

21
MATERIAL AND METHODS

Figure 2-2: AdddddddddddddddddddddddIBMS KMU

sssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssss
sssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssss
ssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssss as appendix
A.137,139–143

2.2 Study Chemicals – Details and Doses

ddddddddddddddddddddddddddddddddddddddddddddddddddddddddddddddddddddd
ddddddddddddddddddddddddddddddddddddddddddddddddddddddddddddddddddddd
ddddddddddddddddddddddddddddddddddddddddddddddddddddddddddddddddddddd
ddddddddddddddddddddddddddddddddddddddddddddddddddddddddddddddddddddd
ddddddddddddddddddddddddddddddddddddddddddddddddddddddddddddddddddddd
ddddddddddddddddddddddddddddddddddddddddddddddddddddddddddddddddddddd
ddddddddddddddddddddddddddddddddddddddddddddddddddddddddddddddddddddd
dddddddddddddddddddddddddddddddddddddhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhh
hhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhh (Figure 2-3, Figure 2-4 and Error!
Reference source not found.). The important chemical details have been given in Table
2-1 and Table 2-2.

22
MATERIAL AND METHODS

Table 2-1: Details of the study chemicals administered to treatment groups

Chemical Physical Concent- Supplier Use Dose calculation


state ration

Table 2-2: Details of laboratory chemicals used in the study procedures

Chemical Physical Concent- Supplier Use Dose calculation


state ration

23
MATERIAL AND METHODS

Figure 2-3:
ccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccccc, IBMS
KMU

24
MATERIAL AND METHODS

Figure 2-4: ggggggggggggggggggggggggggggggggggggggggggggggggggggggggggggggg

25
MATERIAL AND METHODS

2.3 Research Study Design

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xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
xxxxxxxxxxxxxxxxxxxxxxxxxx12,38,144
xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.118,121,125,126,145
xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
xxxxxxxxxxxxxxTable 2-3, which shows
xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
xxxxxxxxxxxxxxxx.29,30

xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
xxxxxxxxxxxxxxxxxxxxxxxxxxx (Figure 2-9).29,30
xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
xxxxxxxxxxxxxxxxxxxxxxxxxxxx).146–148

Table 2-3: ffffffffffffffffffffffffs29,30

26
MATERIAL AND METHODS

Figure 2-5: Concept map cccccccccccccccccccccccccccccccccccccccccccccccccccccccccccc

Figure 2-6: ggggggggggggggggggggggggggggggggggggg

Scheme for the 2-Phase Subacute Study

27
MATERIAL AND METHODS

2.4 Research Study Period

ggggggggggggggggggggggggggggggggggggggggggggggggggggggggggggggggggggg
ggggggggggggggggggggggggggggggggggggggggggggggggggggggggggggggggggggg
gggggggggggg.138,149,51

Figure 2-7: Process of preparation ggggggggggggggggggggggggggggggggggggggggggg, IBMS


KMU

2.4.1 Specimen Collection and Fixation

dddddddddddddddddddddddddddddddddddddddddddddddddddddddddddddddddddddd
ddddddddddddddddddddddddddddddd in appendix B.152,153

28
MATERIAL AND METHODS

2.5 Processing

2.5.1 Tissue Samples Arrangement and Grouping

Figure 2-8: fffffffffffffffffffffffffffffffffffffff

2.5.2 Tissue Processing – Setting

ddddddddddddddddddddddddddddddddddddddddddddddddddddddddddddddddddddd
ddddddddddddddddddddddddddddddddddddddddddddddddddddddddddddddddddddd
dddddd (Error! Reference source not found., Error! Reference source not found. an
d Error! Reference source not found.).

29
MATERIAL AND METHODS

2.5.3 vvvvvvvvvvvvvvvvvvvvvvv:

i. ggggggggn:

Thhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhh
hhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhh
hhhhhhhhhhhhhhhhhhhh.

ii. Dhhhhhhhhhhhhhon:

hhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhh
hhhhhhhhhhhhhhhhhhhhhhh.

2.6 Lggggggggggggggggggggggg

2.6.1 hhhhhhhhhhhhhhhhhhhhhhhhhhhhhhh

ggggggggggggggggggggggggggggggggggggggggggggggggggggggggggggggggggggg
ggggggggggggggggggggggggggggggggggggggggggggggggggggggggggggggggggggg
gggggggggggggggggggggggggggggggggggggggggggg.

30
MATERIAL AND METHODS

31
MATERIAL AND METHODS

32
MATERIAL AND METHODS

33
MATERIAL AND METHODS

2.7 Statistical Analysis of Data

ggggggggggggggggggggggggggggggggggggggggggggggggggggggggggggggggggggg
ggggggggggggggggggggggggggggggggggggggggggggggggggggggggggggggggggggg
ggggggggggggggggggggggggggggggggggggggggggg Figure 2-38.

2.7.1 Hypothesis based results methodology

Based on research question and objectives of this study, the alternate hypothesis (Ha)
was as follows;

Ha =
ddddddddddddddddddddddddddddddddddddddddddddddddddddddddddddddddddddd

34
MATERIAL AND METHODS

ddddddddddddddddddddddddddddddddddddddddddddddddddddddddddddddddddddd
ddddddddddddddddddddddd

The details related to study hypothesis, indicators, result methodology and type of
statistics applied have been elaborated in the Error! Reference source not found..

Independent Dependent
Variable X Variable Y

CAUSE RESPONSE

Categorical/ i) Ordinal
Nominal ii) Continuous

Figure 2-9: Concept map showing the levels of


measurements of the study variables in general

35
MATERIAL AND METHODS

Figure 2-10: Classification hierarchy for the variables of this research study in particular

2.7.2 Statistical tests

During the whole study duration all different important data were consistently recorded
in Microsoft Excel. After obtaining, organizing and coding all the results in Excel, they
were finally imported into SPSS for applying the proper statistical analysis tests.

2.7.2.1 Descriptive statistics

Descriptive statistical analysis was conducted in SPSS to describe all the qualitative
and quantitative variables included in this study. Variables were represented by
mean ± standard deviation (SD) (Error! Reference source not found.).

The quantitative data was also analyzed for independence, normality and
homoscedasticity (homogeneity of variance) by applying the required tests to meet the
assumptions of parametric statistical tests.

36
MATERIAL AND METHODS

37
3 RESULTS

This experimental study was designed to


xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx. The results which have been achieved show
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xxxx.

xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.

3.1 Results as per Study Objectives


The results were structured on the study objectives as follows:

1. Xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx

2. xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
x

3.2 Study Parameters (Dependent Variables) for Results:

1. Sssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssss
sss

2. Ssssssssssssssssssssssssssssssssssssssssssssssssss

3. sssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssssss

3.2.1 General Observations

ggggggggggggggggggggggggggggggggggggggggggggggggggggggggggggggggggggg
ggggggggggggggggggggggggggggggggggggggggggggggggggggggggggggggggggggg
ggggggggggggggggggggggggggg.
38
DISCUSSION

ffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffffff
fffffffffffffffffffffffffffffffffffffffff

Figure 3-1: Comparison oddddddddddddddddddddddddddddddddddddddddddddddddddddds

39
DISCUSSION

Figure 3-2: Mean absolute liver weights of the rat subgroups based on mean ± standard
deviation
Bar chart showing group wise means of the absolute liver weights in the form of column bars
(blue) along with the standard deviation error bars (red).

40
DISCUSSION

3.3 ddddddddddddddddddddd
ddddddddddddddddddddddddddddddddddddddddddddddd (section Error! Reference s
ource not found.).
ddddddddddddddddddddddddddddddddddddddddddddddddddddddddddddddddddddd
dddddd (section Error! Reference source not found.) and finally processed for s
tatistical analysis using SPSS. The significant results thus obtained as well as the
comparisons among various treatment groups (independent variables) based on the
observed histological outcomes (dependent variables) have been presented in this
section.

41
DISCUSSION

Figure 3-3: Severity grades of the treatment groups derived from the “Modified scoring criteria
for liver grading”
Normal = Grade 0 (-, 0%); Minimal = Grade 1 (+, 25%); Mild = Grade 2 (++, 50%); Moderate=
Grade 3 (+++, 75%); Marked= Grade 4 (++++, 100%) (Error! Reference source not f
ound.)

3.3.1 Objective based results for hypothesis testing

As explained earlier, overall histological scoring and the statistical analysis of all the
study parameters and the comparisons among all the study subgroups had been
assembled to test the study hypothesis. The results for each objective are as follows:

Objective 1:

3.3.1.1 ggggggggggggggggggggggggggggggggggggggggggg?

 Ggggggggggggggggggggggggggggggggggggggggggggggggggggggg

 gggggggggggggggggggggggggggggggggggggggg)

42
4 DISCUSSION

4.1 Overview

SSSSSSSSSSSSSSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN
nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnn
nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnn.67
nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnn
nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnn
nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnn
nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnkkkkkkkkkk
kkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkk
kkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkk.95,108
hhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhh
hhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhh
hhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhh.100,101

The crux of our


jjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjj
jjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjj.

4.2 gggggggggggggggggggggggggggggg

hhhhhhhhhhhhhhhhhhhh

hhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhh.45,158
jjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjj
jjjjjjjjjjjjjjjjjjjjjjjjjjjjjjjj,27 l.,160
kkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkk
kkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkkk
kkkkkkkkk

43
DISCUSSION

4.3 Objective 1: dddddddddddddddddddddddddddddddddddd

ddddddddddddddddddddddddddddddddddddddddddddddddddddddddddddddddddddd
dddddddddddddddddddddddddddd.27,159,164–171
dddddddddddddddddddddddddddddddddddddddddd.27

4.4 Objective 2:

fffffffffffffffffffffffffffffffffffffffffffffffffffffffffggggggggggggggggggggggggggggggg
gggggggggggggggggggggggggggggggggggggggggggggggggggg.178

4.5 Objective 3: dnnnnnnnnnnnnnnnnnnnnnnnnnnnnn

).

nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnn
nnnnnnnnnnnnnnnnnnnnnnnnn.180–184

hhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhhh.98,118,121,145,185,186
xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.

4.6 Limitations

Like most of the scientific works which face one or the other type of limitations namely;
study design limitation, impact limitation and statistical/data limitation, our study also
had certain constraints, some already stated above, that might had an impact on the
interpretation of our research findings to some extent.191,192

i. The main study design limitation


xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.

Another possible constraint


xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
xxxxxxxxxxxxx.

44
DISCUSSION

ii. Regarding impact limitation,


ddddddddddddddddddddddddddddddddddddddddddddddddddddddddddddddddddddd
dddddddddddddddddddddddddd

iii. Regarding data and statistical


limitationddddddddddddddddddddddddddddddddddddddddddddddddddddddddddddd
ddddddddddddddddddddddddddddddddddddddddddddddddddddddddddddddddddddd
dddd

45
5 CONCLUSION

Conclusions

 dddddddddddddddddddddddddddddddd.

 dddddddddddddddddddddddddddddddddddddddddddddd period.

 ddddddddddddddddddddddddddddddd

 ddddddddddddddddddddddddddddddddddddddddddddddddddddd.

Recommendations

 Further research needs


ddddddddddddddddddddddddddddddddddddddddddddddddxxxxxxxxxxxxxxxxxx
xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.

 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx.

 xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx

To sum it up, it is recommended to further explore


ccccccccccccccccccccccccccccccccccccxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
xxxxxxxxxxxxxxxxxxx

All the findings of the study


ccccccccxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
xxxxxxxxxxxxxxxxxxxxxxxxx

46
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APPENDICES
APPENDIX–A

I.

71

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