Professional Documents
Culture Documents
Leukocyte Emigration
Adhesion ▪ TNF and IL-1 ➔ Cellular adhesion ICAM and VCAM Integrins (CD18)
molecules (ICAM and VCAM)
▪ C5a ➔ Integrins
Resolution Neutrophils undergo apoptosis and disappear within 24 hours after resolution of
the inflammatory stimulus
Chediak-Higashi syndrome
Introduction/Epidemiology
▪ Catalase + organisms (All bacteria produce H2O2. Catalase- can’t degrade accumulated
H2O2 which is used by host cells to generate HOCl- even in absence of NAPH Oxidase.
Catalase + can degrade H2O2 produced by themselves)
a) Staphylococcus aureus
b) Burkholderia Cepacia
c) Pseudomonas cepacia
d) Serratia marcescens
e) Nocardia