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Few Listing on the ability of ECP

IECP initially developed to treat coronary artery disease has over a few decades developed into
a complete Anti-aging rejuvenating modality that has taken the medical field to a new level.
IECP is the Ultimate Preventive Health Maintenance Tool With Unparalleled Longevity and Anti-
Aging Potential. As circulation plays an important part in wellbeing IECP or ECP has no parallel
to it. IECP is a brand name that developed machines that are better than any other
manufacturer in the world and ECP or EECP is the modality.

The most notable degenerative process is aging, which can be defined as a reduction in
circulating stem cells. IECP has been proven to increase the level of circulating stem cells.
Therefore, it is likely to slow the effects of aging.

IECP offers unparalleled therapeutic benefits, as well as amazing potential to prevent or slow
the onset of many conditions, including aging. As we age, our microcirculation diminishes. This
affects the flow of blood, oxygen and nutrients to our cells. Without adequate oxygen and
nutrients, cells gradually become less effective and die.

During IECP reversed force (from legs to heart) of oxygenated blood flow increases. Important
hormones, gases and cells are secreted within the entire arterial system. Nitric oxide (NO) is a
molecule that contributes to dilation (widening) of the artery wall to increase blood flow
throughout the body and all organs increasing VEGF.

Vascular endothelial growth factor (VEGF) is a hormone that has been shown to stimulate
growth of new collaterals and improved arterial function. VEGF is critical to the process of
angiogenesis during treatment when new pathways form and naturally bypass blockages.

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Progenitor cells and hematopoietic cells are dislodged from arterial walls and enter circulation.
The new stem cells replace old cells and repair damaged tissue while promoting regeneration of
the arterial system and organs throughout the body. Circulating stem cells restore, repair,
recover and regenerate damaged tissue in the heart and all other organs. Inflammation within
the body decreases, inflammation is known to be the balance between health and disease.
Increasing circulating stem cells is a component of regenerative therapy. In the process, ECP
develop new pathway around blocked arteries in the heart and other parts of the body by
expanding network of tiny blood vessels (collaterals) that help increase and normalize blood
flow to not only the heart muscle but many other organs. For this reason, it is often called the
NATURAL BYPASS.

IECP treatment for Stroke.

What is a Stroke?

A stroke is more popularly known as a ‘heart attack of the brain.’ It is caused by a sudden
blockage of an artery in the brain, just as a heart attack is caused by a sudden blockage in an
artery in the heart. The most common ones are called ‘Ischemic Strokes’, as they are a result of
lack of blood and oxygen in the brain.

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This blockage is caused by blood clots in the arteries that deliver blood to the brain. The blood
clots could develop due to the development of fatty deposit in the lining of the blood vessels,
which narrows the arteries. Loss of blood to the brain results in a loss of oxygen and the brain
cells become injured or die, resulting in progressive brain damage, permanent disability or
death. Ischemic stroke is a heterogeneous disease and constitutes 80% of all strokes. The main
problem of stroke is that there is not enough blood getting to the focal cerebral region, strategies
to improve cerebral blood flow (CBF) can play an important role in acute stroke management

IECP Treatment not only improves blood circulation in the heart, it also improves blood flow to
the brain. This majorly helps in stroke management and recovery. The treatment leads to
increased cerebral blood flow and the improved cardiovascular health. There is accumulating
evidence that IECP therapy improves cerebral blood flow (CBF). A study showed that the mean
carotid flow velocity integral increased by 22% during ECP, with an average peak carotid
diastolic flow velocity of 56 cm/sec, which is 75% as high as the systolic wave.

ECP for Erectile dysfunction treatment

IECP is considered a wonder treatment for patients suffering from erectile dysfunction ( ED ).

The European Male Aging Study defined “late-onset hypogonadism” as reduced sex drive,
erectile dysfunction (ED), and decreased frequency of morning erections, coupled with a lower
testosterone level.

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Because testosterone is the driver of sexual desire, low levels of this hormone are intimately
linked with loss of libido. However, it is not the primary cause of ED as more often this vexing
problem is related to vascular disease.

NO = Nitric Oxide

(Nitric oxide is made by the blood vessels’ lining, or endothelium. The endothelium is exquisitely
sensitive to the physical and chemical conditions inside our blood vessels. When the
endothelium senses heart-healthy conditions, such as physical activity and low cholesterol, it
releases more nitric oxide. And that’s a very good thing. Nitric oxide expands the blood vessels,
increasing blood flow and decreasing plaque growth and blood clotting. )

Erections occur when nitric oxide (NO), a messenger molecule in the endothelial cells lining the
arteries, signals the smooth muscles of the penile arteries to dilate, which engorges the penis
with blood. If blood flow is compromised—as it is in individuals with heart disease, hypertension,
peripheral artery disease, and diabetes—you’re obviously more likely to have problems. In fact,
Australian researchers recently discovered that ED is strongly predictive of future heart attacks
and other cardiovascular events, especially when it occurs in younger men.

ED – Erectile Dysfunction

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( Erectile dysfunction (ED) is the inability to get or keep an erection firm enough to have sexual
intercourse. It’s also sometimes referred to as impotence. )

Many prescription drugs make matters worse. For example, beta blockers and diuretics, often
given to men with hypertension, can make it difficult to achieve an erection, and SSRI
antidepressants cause ED in up to one-quarter of men who take them. Other popular drugs that
impair sexual function include statins, antihistamines, and tranquilizers.

IECP = Increased External Counter Pulsation

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( Increased external counter pulsation (IECP) is a noninvasive treatment modality which can
increase arterial blood flow in peripheral and coronary arterial disease. Several studies have
demonstrated an increase in the flow of the internal iliacal artery and in carotid and renal
perfusion during IECP treatment. )

Increased external counter pulsation (IECP) is a noninvasive treatment modality which can
increase arterial blood flow in peripheral and coronary arterial disease. Several studies have
demonstrated an increase in the flow of the internal iliacal artery and in carotid and renal
perfusion during IECP treatment.

The effects of IECP on ED were discovered serendipitously when men undergoing this therapy
for heart disease had unexpected improvements in erectile function. This outcome, which has
since been confirmed in clinical studies, makes perfect sense—IECP increases NO levels,
improves blood flow, and stimulates the formation of new blood vessels.

The benefits of IECP for treating heart disease and diabetic neuropathy are undeniable.
Additionally, IECP benefits virtually any condition in which poor circulation plays a role. These
include, but are not limited to: erectile dysfunction, kidney disease, memory disorders,
Parkinson’s disease, peripheral vascular disease, vision problems, and more.

ECP for Alzheimer’s disease

Alzheimer’s is the most common cause of dementia among older adults. Dementia is the loss of
cognitive functioning—thinking, remembering, and reasoning—and behavioral abilities to such
an extent that it interferes with a person’s daily life and activities. Dementia ranges in severity
from the mildest stage, when it is just beginning to affect a person’s functioning, to the most
severe stage, when the person must depend completely on others for basic activities of daily
living.

The causes of dementia can vary, depending on the types of brain changes that may be taking
place. Other dementias include Lewy body dementia, frontotemporal disorders, and vascular
dementia. It is common for people to have mixed dementia—a combination of two or more
disorders, at least one of which is dementia. For example, some people have both Alzheimer's
disease and vascular dementia.

There is a strong correlation between Alzheimer’s disease (AD) and poor Cerebral Blood Flow
(CBF). Cognitive decline occurs naturally with age, however a more severe decline, as in Mild
Cognitive Impairment (MCI), is a precursor to AD. Observational studies have shown that the

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treatment of vascular risk factors including: hypertension, diabetes, cerebrovascular diseases,

and hypercholesterolemia, decrease the risk of dementia progression.

Physical exercise is the most basic and efficient way to improve blood flow. Physical exercise
has been shown to increase cardiac output, which in turn leads to an increase in CBF. Studies
have shown that elderly patients who partake in physical activity are less likely to develop
dementia and experience cognitive decline. Due to cognitive or physical decline, patients with
signs of dementia are not always able to exercise. The External Counter pulsation (ECP)
therapy system is a non-invasive device. Traditionally, ECP is used to treat patients with chronic
angina and Congestive Heart Failure (CHF) by increasing cardiac output and reducing the
workload of the heart. ECP increases cardiac output by improving systolic unloading and
venous return. Patients with CHF have an increased risk of cognitive dysfunction presumably
because of decreased CBF.

ECP therapy resulted in improvement in all cognitive domains except visual and verbal memory
tests in patients with CHF. Thus, ECP may be used as an exercise alternative to increase CBF.
The effects of ECP may act similarly to exercise therapy and are explored for patients with MCI.

ECP for Hearing disorders and Tinnitus.

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The established therapeutic principle for sudden deafness and tinnitus is based on the
stimulation of the inner ear perfusion by infusion therapy using vaso-active or hemodilutive
agents.

Concerning a mechanically induced increase of the inner ear's blood supply, the technique of
External Counterpulsation (ECP) is performed. Due to an ECG-guided pneumatic compression
of the lower extremities during diastole an increase of arterial perfusion of the extracranial
supplying brain vessels can be obtained by ECP-treatment.

The determination of a positive correlation between vascular flow increase in the extracranial
brain-supplying vessels during ECP-treatment and the encouraging therapeutic results obtained
by audiometry seem to make this new and promising therapeutic option effective, practicable
and easy to handle. These preliminary results of the ECP technique should be validated in
further studies featuring larger numbers of patients suffering from therapy-resistant inner ear
disorders.

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ECP for Peripheral Vascular Disease

Do you have pain and cramping in your calf or thigh muscles after walking or climbing stairs?
Does one leg or foot feel numb, weak, or colder than the other? Have you experienced hair loss
or slow-healing sores in your lower extremities?

These are the signs and symptoms of peripheral artery disease (PAD), a common and
potentially serious condition that affects one in 20 middle-aged person and one in five people
over age 70. PAD is to the legs what coronary artery disease is to the heart. Diseased,
narrowed arteries (atherosclerosis) compromise blood supply to the lower extremities, and the
pain that comes with exercise, called intermittent claudication, is essentially angina of the legs.

Conventional physicians treat PAD like they treat coronary artery disease—with drugs,
angioplasty, stents, and bypass of blockages in the arteries of the legs. But as with heart
disease, this approach is foolhardy and shortsighted. It may relieve symptoms, but it does not
tackle the underlying problem. It’s simply an invasive, expensive, temporary fix.

Atherosclerosis is a systemic disorder, and it needs to be treated as such by addressing

underlying risk factors, making lifestyle changes, improving nutritional status, and, if necessary,
using noninvasive treatments to improve circulation and arterial health.

External Counterpulsation (ECP) is a mechanical therapy that rhythmically squeezes the lower
extremities, forcing blood up through the legs and dramatically enhancing circulation. ECP
works on multiple levels to heal diseased blood vessels. It reduces stiffness of the arteries and
makes them more flexible and responsive, boosts the release of nitric oxide (a potent

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vasodilator), and stimulates the growth of new vessels around blocked arteries. Consequently,
this therapy produces improvements in chest and leg pain, increases in exercise capacity, and
often results in reduction of medications.

Although ECP has been studied primarily as a treatment for coronary artery disease, it benefits
the entire vascular system. PAD patients who are treated with ECP have predictable
improvements in circulation in the legs that allow them to walk longer before pain sets in.
Although ECP may not be suitable for some patients with extremely severe disease, but it will
become a routine treatment for PAD in the near future.

IECP Treatment for Diabetes

In addition to the improved blood circulation in the heart and the body, the ECP Treatment has
an additional positive effect on diabetics – improved blood sugar control. As blood flow to the
pancreas increases, the insulin production is enhanced, thus improving the overall blood sugar
control. This will lead to long term management of diabetes.

A recent study published in the Journal of Applied Physiology showed marked improvement in
several functions in a group of type 2 diabetic patients. The randomized controlled study was
designed to evaluate the effects of Enhanced Counterpulsation ECP on fasting glucose and
insulin levels, glucose tolerance, arterial function and capillary density in patients with abnormal
glucose control.

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The results were quite remarkable. The authors demonstrated that ECP therapy (35 sessions)
did the following:

 Lowered fasting glucose

 Insulin sensitivity increased
 Decreased markers of insulin resistance
 Lowered plasma glucose after oral glucose tolerance testing
 Muscle biopsies showed increased capillary density
 Increased plasma nitric oxide levels
 Decreased levels of lipid peroxides (free radicals)
 Increased Vascular Endothelial Growth Factor (VEGF), which creates new healthy blood
vessels.
 Increase in glucose transporter 4 protein expression (GLUT 4), which facilitates transport
of glucose into cells.

The author's conclusion- "Our findings provide novel evidence that ECP has a beneficial effect
on peripheral arterial function and glucose tolerance in subjects with abnormal glucose
tolerance". All these remarkable changes occurred without changing diet, medication or level of
exercise!

The improvements appear to be as good as, if not better than medication, exercise or diet by
themselves. Until now medication, diet and exercise have been the only treatments available for
type 2 diabetes, but now there is another proven and effective option that is completely risk and
drug-free ECP. The researchers who designed and published this study are to be congratulated
not only for excellence of this well-done study, but for their highly innovative and breakthrough
thinking as to the potential uses of ECP. The basic function of ECP is to deliver blood, oxygen
and nutrients to every cell and organ in the body, which in this case positively impacted the
pancreas, vascular system and insulin receptors among others.

IECP for Diabetic Neuropathy.

What is diabetic neuropathy?

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Diabetic neuropathy is the term used to describe the usually chronic damage to nerves that
occurs as a result of untreated, or inadequately treated, high blood sugar. It results from a
complex sequence of events that leads to damage and destruction of the minute blood vessels
that nourish nerves along their course to the region of the body they serve after leaving the
spinal canal. Each such nerve is a single cell. The longest nerves, much like long chains, are
the most susceptible to damage. If a peripheral nerve (i.e., a nerve cell not contained in the
brain or spinal column) emerging from the spinal column and traveling to the toes were the
thickness of a piece of string, it would be 3 miles in length at frequent intervals along its length,
each peripheral nerve receives nourishment from tiny blood vessels. If any of these tiny blood
vessels are irreversibly damaged, that part of the nerve dies and no signals are conducted in
Peripheral Nerve Diabetic neuropathy.

IECP increases blood flow to the extremities and reduces symptoms of diabetic and peripheral
neuropathy. During 35 one-hour sessions, pressurized cuffs are placed around the lower
extremities. With each beat of the heart, the cuffs contract, squeezing blood up toward the heart
and throughout the body, increasing circulation. This creates new blood vessels that go around
or “bypass” existing blockages. It does this by releasing VEGF, which is a growth factor for
blood vessels. It also stimulates the bone marrow to produce stem cell endothelial progenitor
cells, which stimulate the growth of new blood vessel cells that line your arteries.

ECP was initially developed to treat patients suffering from blockages due to heart disease.
However, it is important to understand that heart disease is not just about blockages. Heart
disease is a systemic condition that affects the entire vascular system. Thus, we need to
address the entire system, not simply open up one or two vessels. ECP treats the entire
vascular system as it bypasses blockages. Thus, benefiting the Diabetic neuropathy patient.

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