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A Novel Approach on Automatic Detection of Optic Disc and Optic

Cup Segmentation

Kavyashree M Dr P V Rao
IV SEM, M Tech (DEC) Professor and R& D Head,
Dept of Electronics and Communication Engg. Dept of Electronics and Communication Engg.
Rajarajeswari College of Engg. Rajarajeswari College of Engg.
Bangalore-74, India Bangalore-74, India
mkavyashree149@gmail.com pachararao@rediffmail.com

Abstract— This paper proposed a novel approach on


Automatic detection of optic disc and optic cup Thus, an automated system will be very beneficial to
segmentation glaucoma assessment by combined the public so that they can do early screening easily
analysis of fundus eye image and patient data. Fundus
image feature extraction and ocular parameter through the online system. Cup-to-disc ratio (CDR) is
evaluation are carried out for image level analysis. The a method that utilized fundus camera modality to
techniques used for feature extraction include color capture the back wall of the retina so that the ratio
model analysis, morphological processing, filtering and between cup disc and optics disc can be measured.
thresholding. Ocular parameters considered are Cup to
Disc Ratio (CDR), Rim to Disc Ratio (RDR), cup to disc The size of the optic disc will remain relatively stable
area ratio and Inferior Superior Nasal Temporal(ISNT) for both healthy and glaucoma patient but the cup disc
ratio of blood vessels in disc region. The CDR, RDR and size will increase proportionally to the severity of the
cup to disc area ratio based on optic disc, cup and rim
are calculated using image measuring techniques.
glaucoma disease. Thus, optic disc size needs to be
determined before the ratio can be calculated.
Keywords- CDR, RDR, ISNT, SVM Classify, Glaucoma
cup to disc ratio, morphological operation. Furthermore, Glaucoma is a chronic eye disease
that leads to vision loss. As it cannot be cured,
I. INTRODUCTION detecting the disease in time is important. Current
This paper described a novel approach towards tests using intraocular pressure (IOP) are not sensitive
automatic glaucoma assessment. The efforts taken to enough for population based glaucoma screening.
develop an automatic glaucoma assessment technique Optic nerve head assessment in retinal fundus images
have an integration of fundus image analysis and is both more promising and superior. This paper
patient data analysis. Finally a combined glaucoma proposes optic disc and optic cup segmentation using
risk analysis is performed and a risk class is labelled super pixel classification for glaucoma screening. In
for each set of input. In fundus image analysis fundus optic disc segmentation, histograms, and center
image is preprocessed and features are extracted. The surround statistics are used to classify each super pixel
feature extraction involves optic disc segmentation, as disc or non-disc. A self-assessment reliability score
optic cup segmentation, optic rim segmentation and is computed to evaluate the quality of the automated
blood vessel extraction. An array centroid method is optic disc segmentation. For optic cup segmentation,
proposed to segment the extracted features into ISNT in addition to the histograms and center surround
quadrants. Then ocular parameters such as CDR, cup statistics, the location information is also included into
to disc area ratio, Inferior RDR, Superior RDR and the feature space to boost the performance. [3]
ISNT Ratio are calculated. [1]

Optic disc segmentation is one of the most


important pre-processing steps in building an accurate
automated glaucoma detection system. Glaucoma is
one of the major causes for blindness, which cannot
be reversed back. Once the nerves are damaged, it
cannot be reconstructed back with our current level of
technology. However, early screening will allow the
ophthalmologist to identify the disease during the
early stages. A prevention step can be taken to limit
the damage and save the remainder healthy nerves. Fig 1. Medical Diagram of an Eye
II. LITERATURE SURVEY enhanced vein region using graph nets and finally
display the segmented result.[4,5]
Gayathri.R et.al [1] this paper proposed a method
Glaucoma is an eye disease which damages the optic A. Pre-Processing:
nerve of the eye and becomes severe over time. It is
caused due to buildup of pressure inside the eye. Pre-processing is an initial stage where the input
Glaucoma tends to be inherited and may not show up MRI image will be taken and resized to 256X256 and
until later in life. The detection of glaucomatous convert it to gray image for further processing.
progression is one of the most important and most
challenging aspects of primary open angle glaucoma Input Retinal Image Pre-Processing
Disc
Cup Segmentation
Segmentation
(OAG) management.

Gopal Datt Joshi et.al [2] described a depth


discontinuity (in the retinal surface)-based approach to
estimate the approach shifts focus from the cup region
Disc to Cup Ratio
used by existing approaches to cup boundary. The Glaucoma Analysis Output Result
Calculation
given sets of images, acquired sequentially, are related
via a relative motion model and the depth
discontinuity at the cup boundary is determined from Figure 2: Architecture of Proposed Architecture
cues such as motion boundary and partial occlusion.
A. Disc Segmentation
Mohd Asyraf Zulkifley et.al [3] proposed Optic
disc segmentation is a crucial step in automated In optic disc segmentation, adaptive histogram
glaucoma detection system through Cup-to-Disc ratio equalization technique is used to improve the contrast
measurement. Recent approaches focus on of a colour image and Gabor filters are used for
deterministic algorithm of RGB or grey model only. texture feature extraction. Combination of these two
In this paper, we proposed a statistically integrated parameters is very useful for classification of each
approach by combining various colour models. The super pixel as disc or non-disc super pixel.
driving motivation is the ability of each colour model t
work accurately in certain environments or cases. B. Cup Segmentation

A.Murthi et.al [4] this method Proposed a method Optic cup segmentation, thresholding and
The optic cup-to-disc ratio (CDR) in retinal fundus binarization can be used. In binarization, depending
images is one of the principle physiological upon the mean value of the entire pixel, each pixel in
characteristics in the diagnosis of glaucoma. The least an image is assigned the value as „1‟or „0‟. If it is
square fitting algorithm aims to improve the accuracy greater than the mean value then it is '1' else it is
of the boundary estimation. The technique used here is '0'.From a gray scale image, thresholding process is
a core component of ARGALI (Automatic cup-to-disc used to create binary images. In this process, if pixel
Ratio measurement system for Glaucoma detection value is greater than some threshold value then that
and Analysis), a system for automated glaucoma risk particular pixel in an image is marked as "object"
assessment. pixels or else it will be considered as "background"
pixels [8]. Typically, an object pixel is assigned a
III. PROPOSED SYSTEM value of “1” whereas a background pixel is assigned a
value of “0.”[6, 7]
The block diagram of the proposed architecture is
shown in fig1. First we collect the retinal images from Normal and abnormal retinal images are collected
the medical data base. Then in the pre-processing from different hospital of different patients for
system retinal images are converted into red glaucoma analysis, early detection of glaucoma
component, green component. Red component is used helpful for slow down the progression of disease.
to extract optic disc and cup areas for detecting Input image is stored in the JPEG image format. Input
Glaucoma. Then extracted optic disc is segmented in RGB image is resize to 256x256 and double the
disc segmentation, by using the segmented disc image for higher precision then converted to
enhance the vein region of retina. And divide the grayscale image by eliminating hue and saturation
and retaining luminance. Green channel is used for
further processing and which contain more Images are stored in JPEG format .The original
information compared to the other blue and red (RGB and NTSC) image is transformed into
channel. Green channel image is used for optic cup appropriate color space for further processes. Optic
and red channel is used for the optic disc cup and disc is segmented by using morphological
segmentation. operations, Hough transform and water shed
segmentation. [8, 9]
Green channel image is applied to the median
filter which removes the noise and smoothens the
edge. Filtered output image is applied to the Start
morphological operations which contain closing,
opening, dilation and erosion operation. Close
operation is a dilation followed by erosion which fill
the gap in that area and by smoothing their edges. RGB to gray Scale Image
Image open operation is erosion followed by dilation.
Output image of morphological operation is applied
to watershed segmentation to extract the boundaries.
Adaptive Histogram
Equalization Technique
Start

Hough Transform
Input Image

RGB to NTSC
Cup Area Disc area

Segmentation Green Morphological


Channel Operation
CDR

Cup Area Disc Area

yes
Abnormal CDR>0.3

Cup to Disc Ratio No

yes
Normal
Normal CDR>03
No
Fig 4.Flowchart 2 of Hough transform

Abnormal
IV. RESULTS

Images are stored in JPEG format .The original (RGB


Stop
and NTSC) image is transformed into appropriate
color space for further processes. Optic cup and disc
Fig 3.Flowchart 1 of Morphological operation
is segmented by using morphological operations, Table 3:Glaucoma analysis
Hough transform and water shed segmentation. SL.N VC VD CDR=VCD/V Glauco
O D D DD ma
analysis
1 59 148 0.3986 Yes
2 65 146 0.4452 Yes
3 40 91 0.4396 Yes
4 39 78 0.500 Yes
5 30 80 0.260 No
6 31 80 0.3875 Yes
(a) (b) (c) 7 29 75 0.3867 Yes
8 48 135 0.3555 Yes
Fig.2.(a)Original image (b)Optic disk (c)Optic cup 9 49 107 0.4579 Yes
Table 1: CDR measurement for normal data base
V CONCLUSION
SL.NO Cup Disc Cup Data Result
Area Area to Base
Disc The cup to disc ratio is an important indicator of
Ratio the risk of the presence of glaucoma in diabetes
1 295.625 884.3750 0.3343 N N patients. In this paper the segmentation of optic disc,
2 366.75 1133.9 0.3234 N N optic cup and smooth their boundaries by
3 264.875 759.6250 0.3487 N N morphological operations will be used. The
morphological operations are efficient to detect the
4 260.870 794 0.3286 N N
cup to disc ratio in glaucoma patients and normal
5 577.25 1230.8 0.4690 N Abn patients and then check the level of disease. If the cup
6 291.25 924.875 0.3149 N N to disc ratio is more 0.3 then those patients are
7 287.625 944 0.3047 N N glaucoma patients and if the disc ratio is less than
8 284.875 1044.8 0.2727 N N
those are normal patient .This operations has been
tested on a different images. Flow chart 1 of
9 273.25 1264.6 0.2761 N N
morphological operation achieved 93.33% accuracy.
10 189.625 939.625 0.2018 N N Flow chart 2 of Hough transform achieved 85%
11 321.50 1192.5 0.2696 N N accuracy.
12 206.5 982.25 0.2102 N N
13 187.625 1106.3 0.1696 N N REFERENCE
14 199.750 1055 0.1893 N N
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