DRUG DOSAGE MECHANISM OF INDICATION & SIDE EFFECTS & ADVERSE EFFECTS NURSING CONSIDERATION

ACTION CONTRAINDICATION
Diphenhydramine 50 mg H1-receptor Indication: CNS: Drowsiness, dizziness,  Monitor cardiovascular
PRN antagonist and Treatment of headache, fatigue, disturbed status especially with pre-
antihistamine intractable insomnia coordination, tingling, heaviness existing cardiovascular
with significant and weakness of hands, tremors, disease.
anticholinergic Contraindication: euphoria, nervousness,  Monitor for adverse effects
activity. High Hypersensitivity to restlessness, insomnia; confusion; especially in children and the
incidence of antihistamines of (especially in children): excitement, older adult.
drowsiness, but similar structure; fever.  Supervise ambulation and
GI side effects are lower respiratory CV: Palpitation, tachycardia, mild use side-rails as necessary.
minor. Effects in tract symptoms hypotension or Drowsiness is most
parkinsonism and (including acute hypertension, cardiovascular prominent during the first
drug-induced asthma); narrow- collapse. few days of therapy and
extrapyramidal angle glaucoma; Special Senses: Tinnitus, vertigo, often disappears with
symptoms are prostatic dry nose, throat, nasal stuffiness; continued therapy.
apparently hypertrophy, bladder blurred vision, diplopia,  Older adults are especially
related to its neck obstruction; GI photosensitivity, dry eyes. likely to manifest dizziness,
ability to suppress obstruction or GI: Dry mouth, nausea, epigastric sedation, and hypotension
central cholinergic stenosis; pregnancy distress, anorexia, vomiting,
activity and to (category C), constipation, or diarrhea.
prolong action of lactation, premature Urogenital: Urinary frequency or
dopamine by neonates, and retention, dysuria.
inhibiting its neonates; use as Body as a Whole: Hypersensitivity
reuptake and nighttime sleep aid (skin rash, urticaria,
storage. in children <12 y. photosensitivity, anaphylactic
shock).
Respiratory: Thickened bronchial
secretions, wheezing, sensation of
chest tightness.