Inhibitor a substance which slows down or prevents a particular chemical reaction or other

process or which reduces the activity of a particular reactant, catalyst, or enzyme.

Irreversible inhibitor they check or stop the chemical reaction by occupying active site or
destroying the globular site

Reversible inhibitor they have weak bond with enzymes and can proceed to both direction they can also
neutralized the effect of substrate concertration

Competitive inhibition occurs when substrate (SS) and inhibitor (II) both bind to the same site on the enzyme. In
effect, they compete for the active site and bind in a mutually exclusive fashion. And only true enzyme can be
product

The other type of inhibition is noncompetitive inhibition . In noncompetitive inhibition, a molecule binds to an enzyme
somewhere other than the active site. This changes the enzyme's three-dimensional structure so that its active site can still bind
substrate with the usual affinity, but is no longer in the optimal arrangement to stabilize the transition state and catalyze the reation

ENZYMES a substance produced by a living organism which acts as a catalyst to bring about a
specific biochemical reaction

ENERGY OF ACTIVATION IN BIOLOGY, activation energy is the minimum energywhich must be

available to a chemical system with potential reactants to result in a chemical reaction. ... The activation
energy of a reaction is usually denoted by Ea and given in units of kilojoules per mole (kJ/mol) or
kilocalories per mole (kcal/mol). OR

ENERGY ACTIVATION reactants must collide with some energy for starting of reaction this energy is
called energy activation

COFACTOR a substance (other than the substrate) whose presence is essential for the activity
of an enzyme

ACTIVATOR this type of cofactor change the shape of enzyme or mold the enzyme which
cause the increase the rate of particular enzyme

For eg amalase enzyme present in sliva increase its activity in the presence of chloride ions

These chloride ions are activator

PHOSTETIC GROUP this type of cofactor thightly permenetly attach with enzyme

For eg FAD HAEME(iron carrier of electron to chtochrome)

COENZYME if cofactor is organic in nature then it is called as coenzyme

For eg NADH VITAMINS

Active site a region on an enzyme that binds to a protein or other substance during a reaction
.