Professional Documents
Culture Documents
2 Hazards identification
· Classification of the substance or mixture
· Classification according to Regulation (EC) No 1272/2008
GHS07
Xi; Irritant
R36: Irritating to eyes.
· Information concerning particular hazards for human and environment: Not applicable.
· Label elements
· Labelling according to Regulation (EC) No 1272/2008
The substance is classified and labelled according to the CLP regulation.
· Hazard pictograms
GHS07 GHS08
37.0
Page 2/7
Safety data sheet
according to 1907/2006/EC, Article 31
Printing date 02.10.2013 Version number 2 Revision: 02.10.2013
3 Composition/information on ingredients
· Chemical characterization: Substances
· CAS No. Description
73-31-4 Melatonin
· Identification number(s) -
· EC number: 200-797-7
· RTECS: AC5955000
5 Firefighting measures
· Extinguishing media
· Suitable extinguishing agents:
CO2, powder or water spray. Fight larger fires with water spray or alcohol resistant foam.
· Special hazards arising from the substance or mixture
Formation of toxic gases is possible during heating or in case of fire.
(Contd. on page 3)
GB
37.0
Page 3/7
Safety data sheet
according to 1907/2006/EC, Article 31
Printing date 02.10.2013 Version number 2 Revision: 02.10.2013
37.0
Page 4/7
Safety data sheet
according to 1907/2006/EC, Article 31
Printing date 02.10.2013 Version number 2 Revision: 02.10.2013
37.0
Page 5/7
Safety data sheet
according to 1907/2006/EC, Article 31
Printing date 02.10.2013 Version number 2 Revision: 02.10.2013
11 Toxicological information
· Information on toxicological effects
· Acute toxicity:
· LD/LC50 values relevant for classification:
Oral LD50 >3200 mg/kg (rat)
· Primary irritant effect:
· on the skin: No irritating effect.
· on the eye: Irritating effect.
· Sensitization: No sensitizing effects known.
· CMR effects (carcinogenity, mutagenicity and toxicity for reproduction)
Oral Reproductive 27 mg/kg (rat)
Repr. 1B
12 Ecological information
· Toxicity
· Aquatic toxicity: No further relevant information available.
· Persistence and degradability No further relevant information available.
· Behaviour in environmental systems:
· Bioaccumulative potential No further relevant information available.
· Mobility in soil No further relevant information available.
· Additional ecological information:
· General notes:
Water hazard class 1 (German Regulation) (Self-assessment): slightly hazardous for water
Do not allow undiluted product to reach ground water, water course or sewage system.
· Results of PBT and vPvB assessment
· PBT: Not applicable.
· vPvB: Not applicable.
· Other adverse effects No further relevant information available.
13 Disposal considerations
· Waste treatment methods
· Recommendation
Must not be disposed of together with household garbage. Do not allow product to reach sewage system.
(Contd. on page 6)
GB
37.0
Page 6/7
Safety data sheet
according to 1907/2006/EC, Article 31
Printing date 02.10.2013 Version number 2 Revision: 02.10.2013
14 Transport information
· UN-Number
· ADR, ADN, IMDG, IATA Not applicable
· ADR, ADN, IMDG, IATA Not applicable
· Transport hazard class(es)
· ADR, ADN, IMDG, IATA
· Class Not applicable
· Packing group
· ADR, IMDG, IATA Not applicable
· Environmental hazards:
· Marine pollutant: No
· Special precautions for user Not applicable.
· Transport in bulk according to Annex II of
MARPOL73/78 and the IBC Code Not applicable.
· UN "Model Regulation": -
15 Regulatory information
· Safety, health and environmental regulations/legislation specific for the substance or mixture
· Philippines Inventory of Chemicals and Chemical Substances Substance is listed.
· Australian Inventory of Chemical Substances Substance is listed.
· Standard for the Uniform Scheduling of Drugs and Poisons Substance is not listed.
· Chemical safety assessment: A Chemical Safety Assessment has not been carried out.
16 Other information
The information in this safety data sheet (SDS) has been prepared with due care and is true and accurate to
the best of our knowledge. The user must determine the suitability of the information for its particular
purpose, ensure compliance with existing laws and regulations, and be aware that other or additional safety
or performance considerations may arise when using, handling and/ or storing the material. The information
in this SDS does not purport to be all inclusive or a guarantee as to the properties of the material supplied,
and should be used only as a guide. British Pharmacopoeia Commission Office makes no warranties or
representations as to the accuracy and completeness of the information contained herein, shall not be held
responsible for the suitability of this information for the user's intended purposes or the consequences of such
use, and shall not be liable for any damage or loss, howsoever arising, direct or otherwise.
· Abbreviations and acronyms:
RID: Règlement international concernant le transport des marchandises dangereuses par chemin de fer (Regulations Concerning the
International Transport of Dangerous Goods by Rail)
ICAO: International Civil Aviation Organization
ADR: Accord européen sur le transport des marchandises dangereuses par Route (European Agreement concerning the International
Carriage of Dangerous Goods by Road)
IMDG: International Maritime Code for Dangerous Goods
IATA: International Air Transport Association
GHS: Globally Harmonized System of Classification and Labelling of Chemicals
(Contd. on page 7)
GB
37.0
Page 7/7
Safety data sheet
according to 1907/2006/EC, Article 31
Printing date 02.10.2013 Version number 2 Revision: 02.10.2013
37.0