INTERNATIONAL ISLAMIC UNIVERSITY MALAYSIA

COURSE OUTLINE

Kulliyyah Centre for Foundation Studies

Department BIOLOGY

Programme BIOLOGICAL SCIENCE, PRE MEDICAL, PRE DENTISTRY, PRE

PHARMACY, PRE ALLIED HEALTH SCIENCE, PRE NURSING
Course Title Biology I

Course Code SHF 1415

Status Core
Level One
Credit Hours 5
Contact Hours 6
Pre-requisites NIL
(if any)

Co-requisites NIL
(if any)

Instructional LECTURE , TUTORIAL, QUIZZES, ASSIGNMENTS AND

Strategies LABORATORY PRACTICALS

Course
LO Method %
Assessment
State weightage 1,2,3,4,5 Lab reports 5
of each type of
assessment. 1,2,3,4,5 Quizzes/Tutorials/Assignments 15

1,2,3,4,5 Mid-Semester Examination 30

1,2,3,4,5 End-of-Semester Examination 50

Total 100
Instructor(s) TBD
Semester Semester I
Offered
Course Synopsis The course will provide coverage of the following topics: the origin of life,
the chemistry of life, introducing important organic compounds, their
structures and roles in the living organism; Ultra structure and functions of
cell components; Activities across the cell membrane; Concepts of cell
division ; The variety of tissues within the animal and plant body; cellular
respiration, the concepts and mechanism of heredity and genetics;
population genetics; concepts of protein synthesis, gene regulation and
application of recombinant DNA technology; The accompanying
laboratory sessions will provide hands-on experience and illustration of the
theories learnt.

Course To enable students:

Objectives 1. The syllabus aims to develop an understanding of biological facts
and principles with an appreciation of their significance.

2. To expose the biological systems as a manifestation of divine

wisdom with a purpose in creation, as opposed to the unifying
approach of blind forces of nature in the epistemology of evolution.

3. To encourage respect for all forms of life

4. To provide a suitable foundation for the study of Biology or related

courses in further higher education, and for professional courses
which require students to have knowledge of Biology when
admitted.

Learning Upon completion of this course, the student should be able to:
Outcomes

1. demonstrate the use of biological facts, concepts and principles at

higher level of education.
2. interpret, analyse, evaluate and apply biological information and
ideas for students to carry out theoretical and experimental activities.
3. develop a proper Islamic attitude and values relating to social
technological, and environmental issues relating to current biology.
4. analyse, evaluate, and to deal with biological information and ideas
logically and critically.
5. demonstrate the use and management of biological materials
according to proper and safe procedures

Content Outlines Weeks Topics Task/Reading

1 Origin of Life
Campbell 8th
Epistemology from the Secular and Islamic edition
perspectives, Hypotheses about the origin of Chapter 4
life, Big Bang Theory, Formation of the solar (pg 59)
system and planet earth, Chemical evolution- Chapter 25
Miller Urey Experiment, Idea about the origin (pg 507-533)
of cells.

1-3 Chemical Foundation of Life

Campbell 8th
Properties of water, The chemistry of carbon, edition
Carbohydrates, Lipid, Protein, Nucleic acid Chapter 2
Technique of analysis: Electrophoresis, (pg 30-45)
Centrifugation, Microscopy. Chapter 3
(pg 46-57)
Chapter 4
(pg 58-67)
Chapter 5
Experiment 1: MICROSCOPY I (pg 68-91)

4 Ultrastructure and Function of the Cell

Campbell 8th
The Cell: Characteristics of cells, The cell edition Chapter
theory, Prokaryotic cell, Eukaryotic cells, 6
Organelles: Structures and functions. (page 94-124)

5 Biological Membranes
Campbell 8th
Properties and components of the cell edition Chapter
membrane, Fluid Mosaic Model, Passive 7
transport, Active transport: Sodium-potassium (page 125-141)
pump and coupled transport, Bulk transport:
Endocytosis and exocytosis.

Experiment 2: MICROSCOPY II

5-6 Enzymes and Kinetics

Campbell 8th
Enzymes, Properties of enzyme, Catalysis and edition Chapter
activation energy, Mechanism of enzyme action 8
and kinetics, Factors affecting enzyme activity, (pg 142-161)
Michaelis- Menton Theory, Inhibitors,
Cofactors, Nomenclature of enzymes, Enzyme
technology.
6 Control of cell cycle
Campbell 8th
The Cell Cycle, Control of cell cycle: edition Chapter
Component of cell cycle control system, 12
Mechanism of cell cycle control. (pg 228-245)
Chapter 18
(pg 373-377)
Experiment 3: WATER POTENTIAL

7-8 Tissue Organization

Campbell 8th
General body architecture: Tissues, organ and edition Chapter
organ system, Epithelial Tissues: Squamous, 40
cuboidal, columnar, stratified, pseudostratified, (pg 852-858)
and transitional, Connective Tissues: Proper
and special connective tissues, Muscles Tissues:
Skeletal, smooth and cardiac, Nervous Tissues:
Neurons and supporting cells.

8-9 Cellular Respiration

Campbell 8th
The ATP molecule. Aerobic respiration: edition
Glycolysis, Pyruvate oxidation, Citric Acid Chapter 9
cycle, Electron transport chain, Calculation of (pg 162-184)
total ATP production by cellular respiration.
Anaerobic respiration: Ethanol fermentation,
Lactic acid fermentation. Metabolism of fat and
protein.

Experiment 4: ENZYME

9 GENETICS
Campbell 8th
Mendel and Laws of Inheritance: Segregation edition
and independent assortment, Test Cross, Back Chapter 14
Cross, and Reciprocal Cross, Allelic (pg 262-285)
Interaction: Codominant , Incomplete Chapter 15
dominant , Polygenes, Epistasis, Multiple (pg 286-303)
Alleles, Lethal Genes, Linkage: Linked genes
and genetic recombination, Genetic mapping,
Pedigree Analysis, Sex-linked genes.
 10 DNA AND PROTEIN SYNTHESIS
Campbell 8th
DNA as the carrier of genetic material: Griffith edition Chapter
experiment and Avery experiment, DNA 16
Replication: The Meselson-Stahl experiment, (pg 305-324)
The process of replication, One-Gene/One- Chapter 17
Polypeptide Hypothesis: Beadle and Tatum (pg 325-350)
experiment, Protein synthesis: Overview of
gene expression, The genetic code,
Transcription, RNA Splicing, Translation,
Differences between bacterial and eukaryotic
gene expression

Experiment 5: TISSUES

10-11 CONTROL OF GENE EXPRESSION Campbell 8th

edition Chapter
Operon: Description of repressible and 18
inducible operons, Trp operon: structure, (pg 351-355)
function, and mechanism, Lac operon:
structure, function, and mechanism.

11 GENETIC CHANGE AND VARIATION

Campbell 8th
Types of variation: Discontinous and continous edition Chapter
variation, Sources of variation, Gene mutation: 17
substitution , insertion, deletion , and inversion, (pg 344-345)
Chromosomal mutation : change in Chapter 24
chromosomal number – aneuploidy and (pg 495-496)
polyploidy, change in chromosome structure-
deletion, inversion, duplication, translocation.

Experiment 6: GENETICS

12-13 POPULATION GENETIC AND

EVOLUTION Campbell 8th
edition Chapter
Gene pool concept, Hardy-Weinberg Law, 23
Selection: Natural and artificial, Reproductive (pg 468-482)
isolating mechanism: Pre-zygotic barriers and Chapter 24
post-zygotic barriers, Speciation: Sympatric and (pg 487-498)
allopatric.
 13-14 BIOTECHNOLOGY
Campbell 8th
Recombinant DNA Technology : Restriction edition Chapter
Endonuclease, vector and host, Gene cloning, 20
Identifying clones carrying gene of interest, (pg 396-423)
Genomic and cDNA library/bank, Polymerase
chain reaction, Restriction Fragment Length
Polymorphisms, Southern blotting, Sequencing
DNA, Applications of DNA Technology,
Important safety and ethical issues.

References Required
1. Campbell N.A., Biology. Pearson Benjamin Cummings, 8th Edition,
2008.
Recommended
1. Audesirk T., Audesirk G., Byers B.E., Biology life on earth.
Pearson Prentice Hall Inc. , 8th Edition, 2008.
2. Brum G., McKane L., Karp G., Biology Exploring Life, John Wiley
& Sons. Inc. 2nd Edition, 1994.
3. Green N.P.O., Stout G.W., Taylor P.J., Soper R., Biological
Science 1 & 2, Cambridge University Press. 3rd Edition, 1998.
4. Kent, M.,(2000), Advanced Biology. Oxford University Press.
5. Raven P.H., Johnson G.B., Losos J.B., Mason K.A., Singer S.R.,
Biology. McGraw-Hill. 8th Edition, 2008.
6. Solomon E. P., Berg L. R., Martin D. W., Biology. Brooks/Cole
Thomson Learning Inc. ,8th Edition, 2008.

Proposed Start OCTOBER 2010 (SEMESTER 2)

Date (Semester)

Batch of Intake 2010/2011 onwards

Students to be
Affected

NOTE:
1. The course outlines should reflect the course description/synopsis and Islamic mission of the
university as well as to provide the room for Islamic critique.
2. Latest editions of textbooks and references should be used unless otherwise necessary or if
the course is classical in nature. Please check with the library to ensure that the books are
up-to-date and incorporating the latest edition.
3. The reference lists shall be presented in accordance with APA bibliographic practices and in
alphabetical order.
4. The reference title shall be italicised or underlined or bold. If in doubt, please consult the
Librarian.
5. Proposed course outlines should be presented to Senate for approval at least two Senate
meetings prior to the course offering.