Professional Documents
Culture Documents
DRUG STUDY
Nursing Responsibilities:
1. Check Doctor’s orders and therapeutic sheet to avoid error in giving the drug.
2. Inform client about the procedure (skin testing) and the purpose of the drug to gain his cooperation and to
increase his awareness.
3. Do skin testing aseptically to check hypersensitivity to the drug.
4. Assess and record baseline data necessary for detection of adverse effects of penicillin derivatives.
5. Prepare the drug aseptically to prevent the introduction of microorganisms.
6. Check the patency of the heplock for infiltration before administration.
7. Administer the drug slowly to prevent vein irritation.
8. Monitor drug reaction after administration of first dose.
9. Use cautiously in client with other drug allergies, especially to cephalosphorins, because of possible cross
allergenicity.
10. Administer penicillins on schedule to ensure stable steady-state concentrations for the duration of therapy.
11. Provide ready access to bathroom and interventions directed at symptom relief if diarrhea occurs.
12. Monitor parenteral administration site for signs of local drug reaction.
13. Observe patient closely. With large doses and prolonged therapy, bacterial or fungal superinfection may
occur.
14. Inform client that stomatitis, upset stomach, nausea, vomiting, diarrhea, and discomfort at injection sites are
typical side effects.
15. Encourage client to eat nutritious foods to boost immune system.
16. Encourage the client to have enough sleep and rest.
17. Educate the client and parents about the different side and adverse effects of the drug and encourage them
to report if they occur.
Frequency: in early AM
Route: rectal
Mechanism of Action:
Unknown. Stimulant laxative that increases peristalsis, probably by direct effect on smooth muscle of the
intestine. Thought to either irritate the musculature or stimulate the colonic intramural plexus. Drug also promotes
fluid accumulation in colon and small intestine.
Desired Effect: This drug is given to the client as a part of the SOP’s for Ultrasound for easier visualization of
the kidneys.
Side Effects:
Nausea, abdominal cramps
Adverse Effects:
CNS: muscle weakness with excessive use, dizziness, faintness.
GI:, vomiting, diarrhea with high doses, burning sensation in rectum with suppositories, laxative
dependence with long term or excessive use, protein-losing enteropathy with excessive use.
Metabolic: alkalosis, hypokalemia, fluid and electrolyte imbalance
Musculoskeletal: tetany.
Nursing Responsibilities:
1. Check Doctor’s orders to avoid error.
2. Inform client and parents on the insertion of the suppositories to gain his cooperation.
3. Use cautiously in patients with hypersensitivity with the drug or its components and in those with
rectal bleeding, gastroenteritis, intestinal obstruction, abdominal pain, nausea, vomiting, or other
symptoms of appendicitis.
4. Insert suppositories as high as possible into the rectum, and try to position suppository against the
rectal wall for easier absorption.
5. Avoid embedding the suppository within fecal material because doing so may delay onset of
action or absorption.
6. Provide ready access to bathroom.
Nursing Responsibilities:
1. Administer ANST.
To prevent hypersensitivity reaction.
2. Do divertional activities according to patient’s personal preference such as reading books
and magazines, listening to music, or socializing with significant others.
To lessen the perception of pain
3. Encourage patient to do relaxation techniques like the use of imagery and deep breathing
technique.
To reduce perception of pain by stimulating descending control system resulting in
reduced pain felt.
4. Eliminate additional stressor/source of discomfort whenever possible.
Patient may experience an exaggeration of pain / a decrease ability to tolerate
painful stimuli of environmental factors is further stressing them.
5. Apply cold/hot compress on the affected part.
Cold may apply on the 4 days post op. Decrease prostaglandins, which intensify the
sensitivity of pain receptors. Hot increasing blood flow to an area and would possibly
contribute to pain production by speeding healing.
6. Instruct patient to notify health care professional if headache, dizziness, somnolence,
tinitus, dry mucous membrane, nausea, GI pain, diarrhea, and bleeding occur.
To anticipate the side effects of drugs.
Nursing Responsibilities
Nursing Responsibilities:
Nursing Responsibilities:
Nursing Responsibilities:
2. Check Doctor’s order.
3. Observe the 10 R’s.
4. Teach patient to perform oral inhalation correctly.
Clear nasal passages and throat.
Breathe out, expelling as much air from lungs as possible.
Place mouthpiece well into mouth as dose from inhaler is released, and inhales
deeply.
Hold breath for several seconds, and exhale slowly.
5. Tell patient to wash inhaler every after used.
6. Do bronchial clapping after nebulization.
7. Instruct patient to do deep breathing and coughing exercise.
8. Warn patient about possibility of paradoxical bronchospasm. Tell him to stop drug
immediately if it occurs.
Nursing Responsibilities:
1. Tell patient to take drug as prescribed, even if symptoms disappear.
2. Advise patient to take drug with plenty of fluids and to avoid antacids, sucralfate,
and products containing iron or zinc for at least 2 hours before and after each dose.
3. Warn patient to avoid hazardous tasks until adverse CNS effects of drug are
known.
4. Advise patient to avoid excessive sunlight, use sunblock, and wear protective
clothing when outdoors.
5. Instruct patient to stop drug and notify doctor if rash or other signs or symptoms
of hypersensitivity develop.
6. Tell patient to notify doctor if he experiences pain or inflammation; tendon
rupture can occur with drug.
7. Instruct patient to notify doctor if loose stools or diarrhea occurs. Inspect
patient’s skin for petechiae.
Nursing Responsibilities:
2. Administer on an empty stomach, one hour before or two hour after meals, with a
full glass of water but with gastric problems take it with meals to facilitate faster
absorption.
3. Do not take the drug with milk and yogurt because milk and yogurt decreases the
absorption of ciprofloxacin.
4. Do not supplement therapy with OTC remedies for infection and physician’s
order to prevent interactions with drugs (e.g. administration of antacids, iron salts,
sucralfate and zinc salts ecreases absorption of ciprofloxacin)
5. Complete full course of medication, even if he feels better to make sure that the
desired effect of the drug is achieved.
6. Emphasize small frequent meals and frequent mouth care to prevent nausea and
vomiting and dry mouth as adverse reaction.
7. Encourage the patient’s family to report any adverse effect of the drug like
tremors, seizures, drowsiness, chest pain, abdominal pain and hallucinations to be able to
give prompt intervention thereby preventing further complications.
8. Encourage the patient not to engage himself to potentially hazard activities that
may require alertness to prevent accident because this drug causes dizziness.
Nursing Responsibilities
1. Instruct patient not to take in drug with milk or antacid, instead take it in with fruit juices
to enhance absorption of the drug.
2. Instruct patient to notify physician if signs and symptoms of anaphylaxis (rash, pruritus,
laryngeal edema, wheezing) occur for immediate interventions to prevent further
complications.
3. Encourage patient to comply with medication regiment to achiev therapeutic effect of the
drug.
4. Tell patient that stools may become dark, green or black as an effect of the drug to avoid
anxiety and for patient not to feel alarmed.
6. Instruct patient to report any adverse reactions such as nausea, epigastric pain, vomiting,
constipation, diarrhea and anorexia to be able to perform immediate actions thereby
preventing further complications.
Nursing Responsibilities:
1. Tell the patient to take the drug recommended schedule and not to skip doses to ensure
the effectiveness and to avoid untoward side effects.
2. Assess patient for profound sedations To be able to provide safety precaution as indicated
(side rails up, bed in low position, call bell within reach, supervision of amputation and
transfer).
4. Instruct patient to avoid concurrent use of alcohol or other CNS depressants to prevent
excess sedation, ataxia, weakness, headache, and paradoxical agitation.
5. Instruct the patient to perform careful mouth care with frequent rinsing, sucking hard
candy, chewing sugarless gums, and increased fluid intake to relieve signs and symptoms
of dry mouth.
6. Instruct patient to report any adverse reactions such as drowsiness, involuntary motor
activity, dry mouth and constipation to be able to perform prompt intervention thereby
preventing further complications.
Nursing Responsibilities:
1. Monitor the vital signs before and after drug administration to have a baseline
data and note changes signifying drug’s effect.
2. Administer the drug as directed by the physician. The drug maybe taken with or
without food to be more effective and to avoid untoward side effects.
3. Emphasize the need for the patient to comply with the diet (low salt, low fat) to
prevent water-attracting sodium that would increase blood volume increasing pressure.
4. Be at the patient’s side or let the watcher look after the patient or do precautionary
measures (raising side rails up) after administering the drug the drug may cause
hypertension, being with the patient will prevent fall.
5. Avoid tasks that require mental alertness until drug effects takes place the drug
may cause dizziness or drowsiness.
Nursing Responsibilities:
1. Instruct the patient to carry medical identification at all times to be able to give proper
medication.
2. Instruct patient about disease and importance of following therapeutic regimen, including
adhering to diet, weight reduction, exercise and personal hygiene programs and avoiding
infection to promote compliance of patient for effective drug therapy.
3. Tell patient to carry candy or any simple sugars to treat mild hypoglycemic episodes.
4. Instruct patient not to change drug without doctor’s consent and to report abnormal blood
or urine glucose test result to monitor effectiveness of the drug therapy and to give
prompt intervention.
5. Tell patient to avoid alcohol to prevent excess sedation, ataxia, weakness, headache, and
paradoxical agitation.
Nursing Responsibilities:
1. Administer the drug as directed by the physician. The drug maybe taken with or without
food to ensure the effectiveness and to prevent stomach upset.
2. Emphasize the need for the patient to comply with the diet low salt, low fat to prevent
water-attracting sodium that would increase blood volume increasing pressure.
3. Tell the patient to take the drug recommended schedule and not to skip doses to ensure
the effectiveness and to avoid untoward side effects.
4. Tell patient to avoid alcohol to prevent excess sedation, ataxia, weakness, headache, and
paradoxical agitation.
5. Instruct patient to avoid driving, doing other tasks or activities that require alertness
because the drug may cause dizziness and lightheadedness.
6. Encourage patient to continue taking drug even when feeling better to ensure that the
desired effect of the drug is achieved.
7. Monitor the vital signs of the patient especially blood pressure during the course of
therapy to evaluate the effectiveness of the drug.
1. Perform drug skin testing before starting course of therapy to determine any allergic
reaction to drug.
2. After mixing the diluents to the vial, shake it carefully. Foaming should dissipate upon
standing. Administer only clear solutions to attain its fullest therapeutic effect.
3. Administer drug not less than 1 hour after dilution to ensure drug absorption.
5. Administer drug slowly because the drug can cause irritation on the veins if rapidly
administered.
6. Inform and instruct client to report to any members of the health team any untoward or
hypersensitivity reaction such as rash, stomatitis, nausea and vomiting, fever or chill so
that they can immediately do necessary interventions and to minimize anxiety to the
client if these reactions will manifest.
7. Hold client in ambulatory care for at least 20 minutes after administration to avoid
possible injury since the drug can cause dizziness and seizure.
8. Instruct client to report any discomfort at the infusion site to detect early signs and
symptoms or complications and for proper nursing intervention.
Nursing Responsibilities
1. Assess fluid balance (I and O, daily wt., edema, lung sounds) throughout therapy. Notify
physician if symptoms of fluid overload (HPN, edema, dyspnea, rales/crackles, frothy
sputum) occur to have a baseline data and prevent complications.
3. Encourage patient to take medication as directed. A missed dose should be taken as soon
as remembered unless almost time for next dose to maintain the therapeutic level of the
drug.
4. Encourage patient not to take milk products because it may decrease the absorption of the
drug.
Nursing Responsibilities
1. Instruct the patient not to take enteric-coated tablets within 1 hour of Calcium Carbonate
to prevent premature dissolution of the tablet.
2. Do not administer with milk to avoid alkali syndrome ( nausea and vomiting, confusion,
and headache).
Nursing Responsibilities
1. Explain therapeutic value of medication prior to administration to enhance the analgesic
effect.
2. Tell the client not to perform activities that require mental alertness to prevent injury
because the drug may cause drowsiness and dizziness and may impair mental or physical
performance.
3. Take the drug only as directed by the physician. May be taken without regard to meals to
ensure the effectiveness of the drug and avoid untoward side effects.
4. Instruct client to report lack of response, and side effects such as nausea, dizziness,
constipation, somnolence, and pruritus to render immediate proper nursing interventions
thus preventing further complications.
1. Inform client that management should include diet control (weight loss, caloric
restrictions and exercise) to help make the drug therapy effective.
conversion to active metabolites it interferes with the synthesis of DNA and also RNA. It
acts by blocking the conversion of deoxyridylic acid to thymidylic acid by inhibiting the
Desired Effect: This drug was given to our client as palliative management for colon
effects like: nausea, vomiting, loss of appetite, effects of the drug given and to inform the
decreased vision, tearing, double vision, client of possible effects so that he could have
cover.
Mechanism of Action:
Active reduced form of folic acid, required for nucleoprotein synthesis and
Desired Effect:
This drug was given to our client in combination with 5 – Fluorouracil for
sores.
* No other side effects have been reported from the use of leucovorin alone. But since it
makes 5-FU more powerful, adding it to a chemotherapy regimen can sometimes result in
Mechanism of Action:
wall. They increase the muscle contractions that move along the stool mass.
Desired Effect:
This drug was given to evacuate the bowel for diagnostic procedures
only for short term therapy. cause electrolyte imbalance and dependency of
bowel tone
2). Advise the patient to take on an empty For rapid effect since results are slowed if
frequent passage of stool as a result of taking in effects of the drug given and to inform the
5). Instruct the client to report if he experience In order to avoid possible injury and to manage
or weakness.
6). Provide thorough patient teaching regarding To enhance patient’s knowledge about drug
drug regimen.
Classification: Laxative
Mechanism of Action:
smooth muscle of the intestine. Thought to either irritate the musculature or stimulate
Desired Effect:
This drug was given to evacuate the bowel for diagnostic procedures
position. suppository.
2). Insert suppository as high as possible into For better stimulation of the smooth muscles
adverse effects such as nausea, vomiting, effects of the drug given and to inform the
abdominal cramps, diarrhea and burning client of possible effects so that he could have
only for short term therapy. cause electrolyte imbalance and dependency of
bowel tone.
Nursing Responsibilities:
1. Encourage patient to wash and clean the wound before applying the
cream to prevent further infection.
2. Instruct patient to only apply on the affected part sparingly to prevent
maceration.
3. Encourage patient to apply carefully and properly on the affected part to
avoid irritation on the surrounding skin and this drug can stain fabric,
hair and the skin.
4. Instruct patient to apply a small amount to cover affected area
completely and avoid use of occlusive wrapping or dressing to ensure
that the applied cream is in tact on the affected area.
5. Encourage patient to report increase skin irritation and lack of response
to therapy, itching, redness, pain and local hypersensivity reactions to
give immediate interventions.
daily activities for 25- 30 mins until and not to interfere with the activies
minor adverse effects such as transient local regarding the side effects of the drug
Nursing Responsibilities:
1. Check the doctor’s order to protect self from illegal actions.
2. Observe the 10 R’s before administration for an effective treatment
regimen.
3. Assess patient for abdominal pain. Note presence of blood in emesis,
stool, or gastric aspirate.
4. Advise patient to report abdominal pain and blood in stool or emesis.
5. Instruct patient to report angioneurotic edema, blurred vision, vertigo,
malaise. burning and itching at injection site.
6. Look out for hematologic side effects like reversible leucopenia and
pancytopenia.
7. Consider Lab Results:
>May increase creatinine and ALT levels.
>May decrease WBC count.
facilitates easy expectoration of the mucus present and cough and volume of