Professional Documents
Culture Documents
c
>
Is readily absorbed from the GIT and peak plasma >Treatment of >Rifampicin: Patients >careful
Brand Name: concentrations of about 7-10 mcg/mL have been reported 2-4 hrs after pulmonary & w/ jaundice. monitoring of
FIXCOM a dose of 600 mg, although there may be considerable interindividual extra-pulmonary >Pyrazinamide: Liver hepatic function.
Generic Name: variation. Food may reduce and delay absorption. Rifampicin is TB. damage, acute gout or
Rifampicin approximately 80% bound to plasma proteins. It is widely distributed hyperuricemia. >check hepatic
150mg in body tissues and fluids and diffusion into the CSF is increased when >Ethambutol: Optic function before
the meninges are inflamed. neuritis. and during
Isoniazid treatment.
75mg >
Is readily absorbed from the GIT. Peak concentrations of
about 3-8 mcg/mL appear in blood 1-2 hrs after a fasting dose of 300 >monitor liver
mg by mouth. The rate and extent of absorption of isoniazid is reduced function and
Pyrazinamide by food. Isoniazid is not considered to be bound appreciably to plasma serum uric acid
400mg proteins and diffuses into all body tissues and fluids, including the regularly.
CSF. The plasma half-life for isoniazid ranges from about 1-6 hrs,
Ethambutol those who are fast acetylators having shorter half-lives. >caution when
275mg assessing visual
>
Is readily absorbed from the GIT. Peak serum acuity in patients
concentrations occur about 2 hrs after a dose by mouth and have been with cataracts to
reported to be about 35 mcg/mL after 1.5 g and 66 mcg/mL after 3 g. make sure that
Pyrazinamide is widely distributed in the body fluids and tissues and changes are not
diffuses into the CSF. The half-life has been reported to be about 9-10 due to the
hrs. It is metabolized primarily in the liver by hydrolysis to the major underlying causes
active metabolite pyrazinoic acid which is subsequently hydroxylated .
to the major excretory product 5-hydroxypyrazinoic acid.
c
c
Brand name: Anti-inflammatory, Relief of mild to moderate Contraindicated with allergy to Administer drug with
Motrin analgesic, and antipyretic pain ibuprofen, salicylates, or other food or after meals if GI
activities largely related to NSAIDs upset occurs.
Generic name: inhibition of prostaglandin >Fever reduction
Ibuprofen synthesis; exact >Use cautiously with CV >Avoid OTC drugs. Many
mechanisms of action are >Prevention and treatment of dysfunction, for impaired renal of these drugs contain
Classes: not known. migraine headache function similar medication, and
serious overdosage can
Inhibits both occur.
5-10mg/kg PO every 6-8 cyclooxygenase(COX) 1
hours; do not exceed 40 and 2. >You may experience
mg/kg/day these side effects:
Constipation, Nausea, GI
upset, dizziness