Answers

Nerve stimulate i.e., action potential generated

1)       ACh dissociates from binding sites a)  (23)  Na+ influx to create action potential

2)       ACh in synaptic cleft b)   (8)Ca2+ binds to troponin

3)       AChE fragments neurotransmitter c)    (28) RMP goes from –90mV to +75mV

4)       action potential to muscle fiber ceases d)   (24) nerve stimulus proceeds    

Action potential at Varicosity

5)       ATP bound to myosin heads is hydrolyzed to e)   (29) synaptic end bulbs also called
ADP by ATPase varicosity    

6)       binding of neurotransmitter to ligand-gated f)   (12)   Ca2+ released    

ion channels

7)       binding sites on the actin are exposed g)  (31)   to stimulate ACh filled vesicles to be
released   

8)       Ca2+ binds to troponin h)  (2)    ACh in synaptic cleft   

9)       Ca2+ lost from troponin i)   (6)   binding of neurotransmitter to ligand-

gated ion channels    

Action potential stimulate the muscle fiber

10)    Ca2+ pumped back into SR (ATP used) j) (35) wave of action potentials spreads in all

directions along membrane      

11)    Ca2+ released k)   (30)  T tubules stimulated to open voltage-

regulated ion gates   

12)    Ca2+ released l)   (34)  voltage-gated calcium channels open  

13)    calsequestrin binds Ca2+ m) (11)  Ca2+ released     

14)    contraction over n)  (17)  from the SR into the cytosol   

15)    crossbridges are formed o)  (1) ACh dissociates from binding sites        

16)    fragments are reabsorbed p)  (3)  AChE fragments neurotransmitter     

17)    from the SR into the cytosol q) (16) fragments are reabsorbed      

Muscle contraction started

18)    K+ diffuses outward r)   (8) Ca2+ binds to troponin     

19)    muscle fiber excited s)   (33) troponin-tropomyosin shifts

20)    muscle fibrils relax t)   (7)  binding sites on the actin are exposed

21)    myosin head cocks and attaches to actin u) (19)   muscle fiber excited     

22)    myosin releases actin v)  (5) ATP bound to myosin heads is hydrolyzed to

ADP by ATPase     

23)    Na+ influx to create action potential w)  (21)  myosin head cocks and attaches to
actin   

24)    nerve stimulus proceeds x)  (15) crossbridges are formed      

25)    nerve stimulus stops y)  (27)   power stroke   

26)    new ATP added z)  (22)    myosin releases actin    

27)    power stroke aa)   (26)  new ATP added

28)    RMP goes from –90mV to +75mV bb)  (25)  nerve stimulus stops

29)    synaptic end bulbs cc) (4) action potential to muscle fiber ceases    

Contraction over due to the cease of action potential

30)    T tubules stimulated to open voltage- dd)  (14) contraction over 

regulated ion gates

31)    to stimulate ACh filled vesicles to be released ee)   (13) calsequestrin binds Ca2+ 

32)    tropomyosin slides back over the myosin ff)  (10) Ca2+ pumped back into SR (ATP used)    
binding sites on actin

33)    troponin-tropomyosin shifts gg)  (9)  Ca2+ lost from troponin

34)    voltage-gated calcium channels open hh)  (32)   tropomyosin slides back over the

myosin binding sites on actin

35)    wave of action potentials spreads in all ii)  (20)   muscle fibrils relax

directions along membrane