HAAD Poison & Drug Information Center ANTIDOTE CHART

Antidote Black widow spider antiserum Atropine sulfate

Indications Black widow spider envenomations Alpha-2 agonists, antimyesthenic agents, bradyarrhythmia-producing agents, cholinergic agonists, muscarine-containing mushrooms, nerve agents, organophosphate and carbamate insecticides food-borne botulism, wound, or interstinal colonization in children or adults( not recommended for infant botulism) Medications causing neuroleptic malignant syndrome Lead, zinc salts poisoning

Botulinum Antitoxin

Bromocriptine mesylate Calcium disodium EDTA Calcium gluconate gel Calcium gluconate INJ

Hydrofluoric acid skin exposure Calcium channel blockers, fluoride salts, hyperkalemia (not digoxin-induced), hypermagnesemia Cyanide antidote kit Cyanide poisoining Cyproheptadine Serotonin syndrome Dantrolene sodium Malignant hyperpyrexia or muscular rigidity Deferoxamine mesylate Iron poisoning Diazepam Digoxin immune Fab Chloroquine and related antimalarial drugs Cardiac glycoside-containing plant ,digitoxin, digoxin Dimercaprol (BAL) Arsenic, copper, gold, lead, lewisite, mercury Diphenhydramine HCL Drug-induced extrapyramidal symptoms Ethanol Ethylene glycol, methanol Flumazenil Benzodiazepines poisoning Folinic acid Methanol, methotrexate, trimetrexate, (Leucovorin Calcium) pyrimethamine, trimethoprim Fomepizole Ethylene glycol, methanol
Glucagon Beta blockers, calcium channel blockers HAAD-PDIC 2008-2009 Page 1

HAAD Poison & Drug Information Center ANTIDOTE CHART

Insulin (Reglular Insulin) L-Carnitine

Beta blockers, Calcium channel blockers

Valproic acid (hyperammonemia, encephalopathy, liver failure) Methylene blue Methemoglobin N-Acetylcysteine Acetaminophen, carbon tetrachloride, other hepatotoxins Naloxone Opioids,alpha-2 agonists, imidazoline decongestants Octreotide acetate Sulfonylurea hypoglycemic agents Phentolamine mesylate Catecholamine extravasation, intradigital epinephrine injection Physostigmine Anticholinergic alkaloid-containing plants, salicylate antihistamines, atropine and other anticholinergic, intrathecal baclofen Phytonadione (vitamin Coumarin and Indandione derivatives, long-acting K1) anticoagulant rodenticides ,warfarin Potassium iodide Prevents thyroid uptake of radioactive iodine tablet Pralidoxime chloride Organophosphate poisning Protamine sulfate Heparin, Low-Molecular -Weight heparin (LMWH) Prussian blue Radioactive cesium (Cs-137), radioactive thallium (Tl-201), and non-radioactive thallium Pyrdoxine Isoniazide, Adjunct to therapy for ethylene glycol intoxication. Scorpion Anti-serum Scorpion Sting Snake Antivenom Snakes bites Sodium bicarbonate Chlorine gas, Hyperkalemia, Serum Alkalinization, Urine Alkalinization: Thiamine Ethanol, Ethylene glycol
Expert advice regarding use of antidotes is available from the PDIC Call us at

800 424
Adapted From Olson, KR (Ed): Poisoning & Drug Overdose. 5th Edition. Note: List is not all-inclusive but reflects agents used more exclusively as antidotes or

antidotal agents used infrequently

HAAD-PDIC 2008-2009

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