About Us ICSCC 2011

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SPEAKERS

Dr. Sushanta Banerjee, Professor, Division of Hematology/Oncology, University of Kansas Medical Center and Research Director, Cancer Research Unit, VA Medical Center, Kansas City, USA Dr. Sharmila Bapat, Scientist D, National Centre for Cell Science (NCCS), Pune India Dr. Chris Bartholomew, Professor, Department of Biological & Biomedical Sciences, Glasgow Caledonian University, Glasgow, UK Dr. Stefan Bohlander, Professor of Molecular Hematology and Oncology, LMU University of Munich, and Laboratory of Leukemia Diagnostics, Dept. of Medicine III, Klinikum Grosshadern, Munich, Germany Dr. Dana Branzei, F.I.R.C. Institute of Molecular Oncology, Milan, Italy Dr. Miranda Buitenhuis, Dept. of Hematology, Erasmus University Medical Center, Rotterdam, The Netherlands Dr. Christian Buske, Professor & Director, Institute of Experimental Cancer Research of the Comprehensive Cancer Center, University of Ulm, and Clinic for Internal Medicine III, Ulm, Germany Dr. Samit Chattopadhyay, Scientist F, National Centre for Cell Science (NCCS), Pune India Dr. Arun Dharmarajan, Winthrop Professor and Associate Dean (South Asia Research Initiatives), Faculty of Life and Physical Sciences, School of Anatomy & Human Biology, The University of Western Australia, Australia Dr. Amit Dutt, Advanced Centre for Treatment, Research and Education in Cancer (ACTREC), Mumbai, India Dr. Shilpee Dutt, Advanced Centre for Treatment, Research and Education in Cancer (ACTREC), Mumbai, India Dr. Dirk Eick, Professor, Institute of Clinical Molecular Biology and Tumor Genetics, GSF National Research Center, Munich, Germany Dr. John Eriksson, Professor, Department of Biology, Turku Centre for Biotechnology, Turku, Finland Dr. Laxman Gangwani, Associate Professor, Department of Biomedical Sciences, Paul L. Foster

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About Us ICSCC 2011

http://www.icscc.in/speakers.html

School of Medicine, Texas Tech University Health Sciences Center, El Paso, USA Dr. Keith Humphries, Director, Terry Fox Laboratory, BC Cancer Agency, Vancouver, Canada Dr. Sirpa Jalkanen, Professor of Immunology, Director of the Center of Excellence in Host Defense Research, MediCity Research Laboratory, University of Turku, Finland Dr. Philipp Kaldis, Principal Investigator, Cell Division and Cancer Laboratory, Institute of Molecular and Cell Biology, Singapore Dr. Aly Karsan, Medical Director, Cancer Genetics Laboratory, Pathology and Laboratory Medicine, BC Cancer Agency, Vancouver, Canada Dr. D. Karunagaran, Professor of Cancer Biology, Dept. of Biotechnology, Indian Institute of Technology, Chennai, India Dr. Petra Knaus, Professor and Group Leader, Institute for Biochemistry, FU Berlin, Germany Dr. Prasanna Kolatkar, Group Leader, Genome Institute of Singapore, Singapore Dr. Priti Kumar, Assistant Professor, Yale School of Medicine, Department of Internal Medicine/Section for Infectious Diseases, Yale University, New Haven, USA Dr. Gopal Kundu, Scientist F, National Centre for Cell Science (NCCS), Pune India Dr. Rajkumar Lakshmanaswamy, Director Basic Science Research, Center of Excellence in Cancer Research,Paul L. Foster School of Medicine, Texas Tech University Health Sciences Center, El Paso, USA Dr. Bachchu Lal, Department of Neurology, Johns Hopkins University, Neuro-Oncology Laboratory, Kennedy Krieger Institute, Baltimore, USA Dr. Girdhari Lal, Scientist D, National Centre for Cell Science (NCCS), Pune India Dr. Sujata Law, Stem Cell Research and Application Unit, Department of Biochemistry & Medical Biotechnology, Calcutta School of Tropical Medicine, Kolkata, India Dr. Lucio Miele, Ergon Professor of Medicine and Pharmacology, Director, University of Mississippi Cancer Institute, University of Mississippi Medical Center, Jackson, USA Dr Mahendra Mishra, Chief Consultant Pathology, Dr Lal Laboratory, New Delhi, India Dr. Laxminarain Misra, Scientist G and Head, Phytochemistry Department, Central Institute of Medicinal and Aromatic Plants (CSIR), Lucknow, India Dr. Nagaraj Nagathihalli, Division of Surgical Oncology, Vanderbilt University School of Medicine, Nashville, USA Dr. Rao Papineni, Senior Principal Investigator, Research and Development, Carestream Molecular Imaging, Carestream Health Inc., Woodbridge, USA Dr. Anu Raghunathan, Scientist, National Chemical Laboratory (NCL), Pune, India Dr. Vijay Rawat, Junior Professor, Institute of Experimental Cancer Research of the Comprehensive Cancer Center, University of Ulm, and Clinic for Internal Medicine III, Ulm, Germany Dr. Deodatta Roy, Professor & Chair, Dept. of Environmental and Occupational Health, Robert Stempel School of Public Health, Florida International University, Miami, USA Dr. Ashok Saluja, Professor and Vice Chair, Department of Surgery, University of Minnesota, Minneapolis, USA Dr. Dhiman Sarkar, National Chemical Laboratory (NCL), Pune, India Dr. Sudip Sen, Department of Biochemistry, University College of Medical Sciences, Delhi, India Dr. Karan Singh, Professor & Chair, Department of Biostatistics, School of Public Health, Center for BioHealth, UNT Health Science Center at Fort Worth, USA Dr. Shree Ram Singh, Stem Cell Regulation and Animal Aging Group, National Cancer Institute, Frederick, USA Dr. Asoke Talukder, Chief Scientific Officer, Geschickten Biosciences, Bangalore, India

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About Us ICSCC 2011

http://www.icscc.in/speakers.html

Dr. Arun Kumar Trivedi, Drug Target Discovery and Development Division, Central Drug Research Institute, Lucknow, India Dr. Sudha Warrier, Assistant Professor, Manipal Institute of Regenerative Medicine, Manipal University, Bangalore, India

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2nd International Conference on Stem Cells and Cancer (ICSCC-2011): Proliferation, Differentiation and Apoptosis 15 - 18 October, 2011 YASHADA Auditorium Rajbhavan Complex, Pune, India

Confirmed Speakers List:

Dr. Sharmila Bapat, Scientist D, National Centre for Cell Science (NCCS), Pune India Ovarian cancer stem cells and transformation-associated pathways Dr. Dana Branzei, F.I.R.C. Institute of Molecular Oncology, Milan, Italy Regulatory mechanisms controlling recombination-mediated damage tolerance events throughout the cell cycle Dr. Miranda Buitenhuis, Dept. of Hematology, Erasmus University Medical Center, Rotterdam, The Netherlands Signal transduction pathways involved in regulation of myelopoiesis Dr. Christian Buske, Professor & Director, Institute of Experimental Cancer Research of the Comprehensive Cancer Center, University of Ulm, and Clinic for Internal Medicine III, Ulm, Germany CDX2: a class III mutation in AML Dr. Samit Chattopadhyay, Scientist F, National Centre for Cell Science (NCCS), Pune India Regulation of CD44 gene splicing and its Implication in cancer Dr. Shilpee Dutt, Advanced Centre for Treatment, Research and Education in Cancer (ACTREC), Mumbai, India p53 and Myelodysplastic Syndrome: A Pre-Leukemic Disorder Dr. Dirk Eick, Professor, Institute of Clinical Molecular Biology and Tumor Genetics, GSF National Research Center, Munich, Germany Modifications of the carboxy-terminal domain of RNA polymerase II (CTD): function of threonine-4 phosphorylation Dr. Laxman Gangwani, Associate Professor, Department of Biomedical Sciences, Paul L. Foster School of Medicine, Texas Tech University Health Sciences Center, El Paso, USA Function of the zinc finger protein ZPR1 in cell proliferation Dr. Keith Humphries, Director, Terry Fox Laboratory, BC Cancer Agency, Vancouver, Canada Unraveling and targeting leukemic stem cell self-renewal function Dr. Philipp Kaldis, Principal Investigator, Cell Division and Cancer Laboratory, Institute of Molecular and Cell Biology, Singapore Loss of Cdk2 and Cdk4 induces a switch from proliferation to differentiation in neural stem cells

Dr. Aly Karsan, Medical Director, Cancer Genetics Laboratory, Pathology and Laboratory Medicine, BC Cancer Agency, Vancouver, Canada Role of microRNAs and innate immune signaling in the myelodysplastic syndromes Dr Aparna Khanna, Dean, School of Science, SVKM's Narsee Monjee Institute of Management Studies (Deemed University), Mumbai, India Stem Cells in Drug discovery Dr. Prasanna Kolatkar, Group Leader, Genome Institute of Singapore, Singapore Towards Synthetic Stem Cell Biology Dr. Priti Kumar, Assistant Professor, Yale School of Medicine, Department of Internal Medicine/Section for Infectious Diseases, Yale University, New Haven, USA RNA Interference-based Cancer Therapy: Promises and Challenges Dr. Gopal Kundu, Scientist F, National Centre for Cell Science (NCCS), Pune India Stroma and tumor-derived osteopontin: role in inflammation, angiogenesis and cancer Dr. Rajkumar Lakshmanaswamy, Director Basic Science Research, Center of Excellence in Cancer Research,Paul L. Foster School of Medicine, Texas Tech University Health Sciences Center, El Paso, USA Pregnancy and Breast Cancer Risk Dr. Girdhari Lal, Scientist D, National Centre for Cell Science (NCCS), Pune India Stem cell transplantation and its therapeutic importance in future medicine Dr. Sujata Law, Stem Cell Research and Application Unit, Department of Biochemistry & Medical Biotechnology, Calcutta School of Tropical Medicine, Kolkata, India Stem Cell Receptor Expression, Bone Marrow Stem Stromal imbalance and apoptosis pattern in ENU induced MDS mice Dr. Lucio Miele, Ergon Professor of Medicine and Pharmacology, Director, University of Mississippi Cancer Institute, University of Mississippi Medical Center, Jackson, USA Targeting cancer stem cells through the Notch signaling pathway Dr Mahendra Mishra, Chief Consultant Pathology, Dr Lal Laboratory, New Delhi, India HLA in Organ Transplantation Dr. Nagaraj Nagathihalli, Division of Surgical Oncology, Vanderbilt University School of Medicine, Nashville, USA Targeting STAT3 to Target Pancreatic Cancer Stem Cells Dr. Rao Papineni, Senior Principal Investigator, Research and Development, Carestream Molecular Imaging, Carestream Health Inc., Woodbridge, USA Advances in Molecular Imaging of Cell and Tissue Based Therapies Dr. Anu Raghunathan, Scientist, National Chemical Laboratory (NCL), Pune, India A Systems Approach To Metabolic Modeling In Cancer: The Warburg Effect Revisited

Dr. Vijay Rawat, Junior Professor, Institute of Experimental Cancer Research of the Comprehensive Cancer Center, University of Ulm, and Clinic for Internal Medicine III, Ulm, Germany The role of the Hox gene associated microRNA 196 in normal and malignant hematopoiesis Dr. Dhiman Sarkar, National Chemical Laboratory (NCL), Pune, India Dr. Sudip Sen, Department of Biochemistry, University College of Medical Sciences, Delhi, India Stem cells for ocular surface reconstruction: from bench to bedside to intellectual property rights an interesting journey in translational research Dr. Karan Singh, Professor & Chair, Department of Biostatistics, School of Public Health, Center for BioHealth, UNT Health Science Center at Fort Worth, USA The effect of external beam radiation therapy on acute myeloid leukemia and myeloma among patients with prostate adenocarcinoma: A competing-risk approach Dr. Asoke Talukder, Chief Scientific Officer, Geschickten Biosciences, Bangalore, India Discovery of Biomarkers for Cancer Prognosis Dr. Arun Kumar Trivedi, Drug Target Discovery and Development Division, Central Drug Research Institute, Lucknow, India Functional inactivation of C/EBPalpha in myeloid leukemia Dr. Sudha Warrier, Assistant Professor, Manipal Institute of Regenerative Medicine, Manipal University, Bangalore, India Cancer Stem Cell from Human Gliomas - Study of Drug Resistance and Role of WNT antagonists Dr. Alexander Kukharchuk, Director, EmProCell Clinical Research Pvt. Ltd., Mumbai, India, Induction of immunologic tolerance and geroprotector effects of embryonic progenitor cell transplantation in rats and mice Dr. Anant Bagul, Chaitanya, Chaitanya Stem cell Therapy Center, Chaitanya Hospital, 133, Parvati Pune Sinhagad road, Pune, India Efficacy of Stem Cell Therapy in Hypoxic Brain Damage leading to cerebral palsy Results : Study of 25 cases

Confirmed Oral Presentations List:

Blocking Akt and NFB Pathways in conjunction with HN gene of Newcastle Disease Virus and TNF- potentiates apoptosis A new strategy to fight cancer Rajmani R.S., Saxena L., Singh P.K., Kumar Rajiv., Saxena S., Chaturvedi U., Sahoo A.P., Ravi Kumar., Sudesh Kumar, Chittlangia R.K., Verma P.C., Tiwari A. K.* Molecular Biology Lab, Division of Animal Biotechnology, Indian Veterinary Research Institute, Izatnagar-243122, India

EXPRESSION OF MMP2 AND MMP9 (GELATINASES A AND B) IN HUMAN COLON CANCER CELLS 1 Ravikumar. G, 2Umadevi.D and 1Dr. C.Uma 1 Department of Biochemistry, Karpagam University, Coimbatore, Tamilnadu 2 Department of Biochemistry, Karpagam Arts and Science College, Coimbatore, Tamilnadu Isolation, Characterization and Gene Expression Analysis of Whartons Jelly-derived Mesenchymal Stem Cells under Xenofree Culture Conditions Parvathy Venugopal and Malancha Ta Stempeutics Research Pvt. Ltd, Manipal Hospital, Bangalore, India. Non-targeted cells need protection against chemotherapeutic drugs. Can Tea be a solution? Debjani Ghosh*, Sandip Pal, Chabita Saha#, Subrata Kumar Dey, School of Biotechnology and Biological Sciences, West Bengal University of Technology, Kolkata, India PATENTING STEM CELL RESEARCH PRODUCTS: ETHICS AND COMMERCE IN STEM CELL RESEARCH Athira P S Research Scholar, UGC Junior Research Fellow, Department of Law, University of Kerala. India Modulatory effects of Crataeva nurvala bark against Testosterone and MNU induced oxidative damage in prostate of male wistar rats D. Guru Kumar1, P. Deepa2, P. Meenakshi1 M.A. Rathi1 and V.K. Gopalakrishnan1, 2 * 1 Department of Biochemistry, Karpagam Arts and Science College, Coimbatore-641021, Tamil Nadu, India. 2 Department of Biochemistry, Karpagam University, Coimbatore-641021, Tamil Nadu, India IDENTIFICATION AND SELF-RENEWAL OF HEMATOPOIETIC STEM CELLS Miss.Gauri S.Patil Research Associate, Intox PVT.LTD, 375 Urawade, Tal.Mulshi, Dist. Pune, Maharashtra, 411042, India Mutational analysis, Drug binding studies and ADME studies of p21 ras protein which is associated with cancer- An in Silico analysis B. HemaLatha Bioinformatics and Biotechnology, SRM University, India Methylation of the APAF-1 and DAPK-1 Promoter Region Correlate with Progression of Renal Cell Carcinoma in North Indian Population Shiekh Tanveer Ahmad1, Wani Arjumand1, Amlesh Seth2, Sana Nafees1, Sumaya Rashid1, Nemat Ali1 and Sarwat Sultana1* 1* Section of Molecular Carcinogenesis and Chemoprevention, Department of Medical Elementology and Toxicology, Faculty of Science, Jamia Hamdard (Hamdard University), Hamdard Nagar, New Delhi 110062, India. 2 Department of Urology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India -110029

Survival and differentiation of Hippocampal Stem Cell Grafts in the epileptic rat brain Kiranmai S. Rai*, M. M. Acharya and A. K. Shetty *Presenting author- Department of Physiology, KMC International Center, Manipal University, Manipal, Karnataka, India A study of breast cancer stem cells isolated from BRCA1 mutated cell lines in comparison to those isolated from cell lines carrying a wild type BRCA1 Mrs. Veena Somasundaram Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, Kerala, India Molecular mechanism of cigarette smoke induced unregulated cell proliferation of human lung cells Neekkan Dey, Dhrubajyoti Chattopadhyay and Indu B. Chatterjee. Department of Biotechnology and Dr. B. C. Guha Centre for Genetic Engineering & Biotechnology, Calcutta University College of Science, Kolkata, India Isolation and characterization of mesenchymal stem cells from menstrual fluid Srividhya, R., Sangeetha Kandoi, O., Karthiklal, T.S., Reena, R., Ajit Kumar, N. R&D Unit, LifeCell International Private Limited, Chennai Assessment of the depletion of fetal bovine serum proteins in mesenchymal stem cell cultures Malini, V., Srividhya, R., Sangeetha Kandoi, O., Karthiklal, T.S., Ajit Kumar, N. R&D Unit, LifeCell International Private Limited, Chennai Examination of the Differentiation Capacity of Bone Marrow Derived- Human Mesenchymal Stem Cells in Early and Late Passages Mahdi Eskandarian Boroujeni a,b, Purushothama Gowda a, Jyothsna Rao, Hamed Hemati Chahardeh Sri Raghavendra Biotechnologies Pvt. Ltd. (SRB), Bangalore, India Pooyagene biotech Co., Science and Technology Park of Shahrekord University, Shahrekord, Iran Marrow Donor Registry India Strategies and Data Leenam Dedhia, Manasi Vijapurkar-Valluri, Shruti Panchpute, Akriti Jain Marrow Donor Registry India, Department of transfusion medicine, Tata memorial hospital, parel, Mumbai, India STRATEGISING PATENTS IN STEMCELL RESEARCH: A MANAGEMENT PERSPECTIVE Rajeev G, Assistant Professor, Co-operative Institute of Management and Technology, Kerala, India WOUND INDUCED EMT SIGNALING: A LIVE CELL APPROACH Krupa Ann Mathew, 1, 2 Srividya S, 1, 2, 3 Santhosh Kumar T R, 1 Radhakrishna Pillai M1 1 Integrated Cancer Research Programme, Rajiv Gandhi Centre for Biotechnology, Thycaud P.O., Poojappura, Thiruvananthapuram 695014, Kerala, India. 2 Indian Academy of Sciences, C. V. Raman Avenue, Post Box No. 8005, Sadashivanagar, Bangalore, Karnataka, India. 3 Department of Biochemistry and Molecular Biology, Pondicherry University, Kalapet, Puducherry, India

ANTIPROLIFERATIVE AND PROAPOTOTIC EFFECTS OF METHANOLIC EXTRACT OF THE LEAVES OF Nyctanthes arbor-tristis Sumathi,S*.,Sowmini,C.M.,Hamsa,D.,Dharani,B.,Sivaprabha,J and Padma,P.R. DEPARTMENT OF BIOCHEMISTRY, BIOINFORMATICS AND BIOTECHNOLOGY AVINASHILINGAM INSTITUTE FOR HOMESCIENCE AND HIGHER EDUCATION FOR WOMEN UNIVERSITY, COIMBATORE 641 043, TAMILNADU, INDIA Pterostilbene induces autophagy and cellular differentiation in MCF 7 cells via ROS dependent pathway Ajanta Chakraborty 1, Naganjaneyulu Bodipati 2, Marija Krstic Demonacos 3, Ramakrishna Peddinti 2, Kaushik Ghosh2, Partha Roy 1, 1Molecular Endocrinology Laboratory, Department of Biotechnology, 2Department of Chemistry, Indian Institute of Technology Roorkee, Roorkee 247 667, Uttarakhand, India, 3Faculty of Life Sciences, Michael Smith Building, University of Manchester, Oxford Road,Manchester,M13 9PT, United Kingdom Molecular Mechanism of a Novel Metastasis Suppressor Gene Lisam Shanjukumar Singh Department of Biotechnology, Manipur University, Canchipur, Manipur, India EpCAM+ cells of HCC and Cirrhosis show equivalent expression levels of stemness genes Ritu Khosla, Nirupma TrehanPati, Binayak Kumar, Shiv Sarin Institute of Liver and Biliary Sciences, Delhi, India TARGETING CANCER STEM CELLS USING INDIAN MEDICINAL PLANTS BEARING SESQUITERPENE LACTONES Naseer Maliyakkal 1, 2 Asmy A.B 1, 2, Annapoorni Rangarajan2, KSR Pai1, Udupa Nayanabhirama1 1 Manipal College of Pharmaceutical Sciences, Manipal University, Manipal, Karnataka, India 2 Department of Molecular Reproduction, Development and Genetics, Indian Institute of Science, Bangalore, Karnataka, India ISOLATION, CULTURE AND CHARACTERISATION OF EMBRYONIC STEM CELL IN BUFFALO Sadhan Bag, B C Das and Gopal Puri Center of Advance Faculty Training, Division of Physiology & Climatology Indian Veterinary Research Institute, Deemed University, Izzatnagar, Bareilly, UP, INDIA CHARACTERISATION OF CANCER STEM CELLS IN HUMAN EPITHELIAL CANCER CELLS Asmy A.B 1, 2, Naseer Maliyakkal1, 2, Annapoorni Rangarajan2, KSR Pai1, Udupa Nayanabhirama1 1 Manipal College of Pharmaceutical Sciences, Manipal University, Manipal, Karnataka 576104, India. 2 Department of Molecular Reproduction, Development and Genetics, Indian Institute of Science, Bangalore 560012, Karnataka, India

Ex vivo Expansion of Hematopoietic Stem/ Progenitor Cells from Human Umbilical Cord Blood on Acellular Scaffolds Prepared from Heterologous Stromal Cell Matrices Abhilasha Tiwari, B.Tech.1,2, Mark A. Kirkland, Ph.D.2 and Gopal Pande, Ph.D.1 1 CSIR-Centre for Cellular and Molecular Biology (CCMB), Hyderabad 500 007, India 2Deakin University, Waurn Ponds, Geelong, VIC 3217, Australia MicroRNA-128 induces apoptosis in human embryonic kidney cells in a p53-dependent manner Neeru Saini and Yogita K. Adlakha Functional Genomics Unit, Institute of Genomics and Integrative Biology, Mall Road, Delhi, India A study to investigate the response of human CD34+ hematopoietic stem and progenitor cells from umbilical cord blood as potent targets of ionizing radiation Angshuman Biswas, Asiti Sarma *, Subrata Kumar Dey Stem Cell Research Laboratory, School of Biotechnology and Biological Sciences ,West Bengal University of Technology, Kolkata, West Bengal, India, *Radiation Biology Lab, Inter University Accelerator Centre (IUAC), Aruna Asaf Ali Marg, New Delhi, India Regulation of DNA double strand break repair by nuclear matrix protein SMAR1 Nidhi Chaudhary and Kiran K Nakka, Samit Chattopadhyay National Centre for Cell Science (NCCS), Ganeshkhind, Pune, India