Eleazar, Elysa Mae S. 302N/Grp.

Aug. 8, 2011 Ms. L. Soriano R.N., M.A.N

Drug Study

Name of Drug
Generic Name: Citicholine Sodium Brand Name: Zynapse, Somazine, Cholinerve Drug Class: CNS Stimulant, Peripheral Vasodilators, Cerebr alActivators, Neurotropics Dosage: 40mg/tab OD Route: Oral

Indication & Contraindication

Indications: Citicholine is indicated in CVD in acute recovery phase in severe s/sx of cerebrovascular insufficiency and incranial traumatism and their sequellae. Citicholin e in CVA, stimulates brain function. Contraindications: Any allergy or hypersensitivity to the drug Hypertonia of the parasympathetic nervous system Use cautiously for pregnancy and lactation Conscious use for patient with renal and hepatic damage

Mechanism of Action
Citicholine increases blood flow and O2 consumption in the brain. It is also involved in the biosysntehsis action.

Adverse Effect
Fleeting and discrete hypotension effect, increased parasympathetic affects, low blood pressure Itching or hives, swelling in face or hands, chest tightness, tingling in mouth and throat

Nursing Responsibilities
Take Citicholine as prescribed Take Citicholine on time Monitor patients neurologic status Note if there are signs of slurring of speech Note for adverse reactions Titter medication when discontinuing Teach patient on how to take the drug

Arrange for regular

follow-ups

Eleazar, Elysa Mae S.

Aug. 8, 2011

302N/Grp.1

Ms. L. Soriano R.N., M.A.N

Drug Study

Name of Drug
Generic Name: Chlorpheniramine Maleate Brand Name: Atarax, ChlorTrimeton, Dimetane, Dimetapp, Dramamine, Optimine, Periactin, Polaramine, PBZ, Vistaril Drug Class: Antihistamines

Indication & Contraindication

Indications: Temporary relief of sneezing, itchy, watery eyes, itchy nose or throat, and runny nose caused by hay fever (allergic rhinitis), or other respiratory allergies. Contraindications: Hypersensitivity to antihistamines; narrow-angle glaucoma; stenosing peptic ulcer; symptomatic prostatic hypertrophy; asthmatic attack; bladder neck obstruction; pyloroduodenal obstruction; MAO therapy; use in newborn or premature infants and in breastfeeding mothers.

Mechanism of Action
Completely blocks the effects of histamine at H1receptor sites; has atropine-like, antipruritic, & sedative effects.

Adverse Effect
Cardiovascular: Bradycardia; extrasystoles; orthostatic hypotension; palpitations; reflex tachycardia; tachycardia. CNS: Confusion; convulsions; disturbed coordination; dizziness; drowsiness; euphoria; excitation; faintness; fatigue; headache; hysteria; insomnia; irritability; nervousness; neuritis; paresthesias; restlessness; sedation; tremor; vertigo. EENT: Acute labyrinthitis; blurred vision; diplopia; dry nose and throat; nasal stuffiness; sore throat; tinnitus. GI: Anorexia; constipation; diarrhea; dry mouth; epigastric distress; nausea; vomiting. Genitourinary: Difficult urination; dysuria; early menses; urinary frequency or retention.

Nursing Responsibilities
Caution patient using
OTC chlorpheniramine that each product has specific dosing instructions and to read package label before using and not to exceed dose or frequency of administration instructions. Advise patient to take each dose without regard to meals, but to take with food if stomach upset occurs. Advise patient or caregiver using oral syrup to measure and administer prescribed dose using dosing syringe, dosing spoon, or dosing cup. Advise patient that if a dose is missed, to take it as soon as possible unless it is nearing time for the next scheduled dose. If it is nearing time for next scheduled dose, advise patient to skip the missed dose and take the next dose at the regularly scheduled time. Caution patient not to double the dose to catch up. Advise patient that if allergy symptoms are not controlled, not to increase the dose of medication or frequency of use but to inform health care provider. Caution patient that larger doses or more frequent dosing does not increase efficacy and may cause excessive drowsiness or other adverse reactions.

Dosage: 40mg/tab OD Route: Oral

Eleazar, Elysa Mae S.

Aug. 8, 2011

302N/Grp.1

Ms. L. Soriano R.N., M.A.N

Drug Study

Name of Drug
Generic Name: Atorvastatin Calcium Brand Name: Lipitor Drug Class: Antihyperlipidemic, HMG-CoA Reductase inhibitor Dose: 40mg/tab OD Route: Oral

Indication & Contraindication

Indication: Adjunct to diet in treatment of elevated total cholesterol, serum triglycerides, & LDL cholesterol & to increase HDL-C in patients with primary hypercholesterolemia & mixed dyslipidemia & primary dysbetalipoproteinem ia, whose response to dietary restriction of saturated fat & cholesterol & other nonpharmacologic measures has not been adequate. Adjunct to diet treat elevated serum triglyceride levels. Contraindication: Allergy to atorvastatin, fungal byproducts, active hepatic disease, or unexplained & persistent elevations of transaminase levels, pregnancy, lactation.

Mechanism of Action
Inhibits HMG-CoA reductase, the enzyme that catalyzes the first step in the cholesterol synthesis pathway, resulting in a decrease in serum cholesterol, serum LDLs & increases serum HDLs; increases hepatic LDL recapture sites, enhances reuptake & catabolism of LDL; lowers triglyceride levels.

Adverse Effect

Nursing Responsibilities

CNS: Headache, Tell patient to take asthenia drug at the same GI: Flatulence, time abdominal pain, each day to cramps, maintain its effects. constipation, nausea, dyspepsia, Instruct patient to heartburn, liver take a missed dose failure as Respiratory: soon as possible. If Sinusitis, pharyngitis its almost time for Other: his next dose, he Rhabdomyolysis should skip the with acute renal missed dose. failure, arthralgia, myalgia Instruct patient to consult prescriber before taking OTC niacin because of increased risk of rhabdomyolysis. Advise patient to notify prescriber immediately if he develops unexplained muscle pain, tenderness, or weakness, especially if accompanied by fatigue or fever.